Dental Age Estimation of 6-15 Year Old Indian Children Using Demirjian Method

Objective: Assessment of tooth development to estimate the age of living subjects isrequired in various disciplines including pediatric dentistry, orthodontics, and forensicdentistry. The most widely used method is the one given by Demirjian et al. in 1973.This method has been tested only a few times in North Indian children, thus the needfor present study.Methodology: Seven left mandibular teeth were assessed from 215orthopantomograms (OPGs) belonging to healthy children aged 6–15 years randomlyselected and were staged according to Demirjian method. Univariate quantitativeanalysis was performed.Results: A general over-estimation of 0.61 years was observed (0.66 years – males and0.56 years – females) (p 0.05). Also, younger age groups had a higher amount of overestimation.Conclusion: The present results support the need for refinement of the populationspecificstandards in Demirjian method, for its further application

Human Rights and the Global Fund to Fight AIDS, Tuberculosis and Malaria: Meeting Report

On March 3-4, 2011, UN staff, donors, and civil society representatives met in New York to discuss how the Global Fund to Fight AIDS, Tuberculosis and Malaria might best operationalize the promotion of human rights and equitable access as one of its five strategic objectives.The meeting covered the following human rights issues related to the Global Fund's 2012-2016 strategy:Scope and content of the Global Fund's human rights commitment and obligation;Promoting human rights in Global Fund-supported programs and advocacy;Oversight and monitoring and evaluation of the Global Fund's portfolio according to human rights criteria;Addressing human rights risks and violations associated with Global Fund grants.Discussion papers on each of these issues, as well as a paper exploring the relationship between human rights and equity, were prepared for the meeting

A feasible route for the design and manufacture of customised respiratory protection through digital facial capture

The World Health Organisation has called for a 40% increase in personal protective equipment manufacturing worldwide, recognising that frontline workers need effective protection during the COVID-19 pandemic. Current devices suffer from high fit-failure rates leaving significant proportions of users exposed to risk of viral infection. Driven by non-contact, portable, and widely available 3D scanning technologies, a workflow is presented whereby a user’s face is rapidly categorised using relevant facial parameters. Device design is then directed down either a semi-customised or fully-customised route. Semi-customised designs use the extracted eye-to-chin distance to categorise users in to pre-determined size brackets established via a cohort of 200 participants encompassing 87.5% of the cohort. The user’s nasal profile is approximated to a Gaussian curve to further refine the selection in to one of three subsets. Flexible silicone provides the facial interface accommodating minor mismatches between true nasal profile and the approximation, maintaining a good seal in this challenging region. Critically, users with outlying facial parameters are flagged for the fully-customised route whereby the silicone interface is mapped to 3D scan data. These two approaches allow for large scale manufacture of a limited number of design variations, currently nine through the semi-customised approach, whilst ensuring effective device fit. Furthermore, labour-intensive fully-customised designs are targeted as those users who will most greatly benefit. By encompassing both approaches, the presented workflow balances manufacturing scale-up feasibility with the diverse range of users to provide well-fitting devices as widely as possible. Novel flow visualisation on a model face is presented alongside qualitative fit-testing of prototype devices to support the workflow methodology

II Congreso Latinoamericano Jurídico sobre derechos reproductivos, 28, 29 y 30 Noviembre de 2011

El II Congreso Latinoamericano Jurídico sobre Derechos Reproductivos se llevó a cabo en Costa Rica en el año 2011, el mismo buscó generar, además de situaciones de reflexión, debate y participación, espacios de capacitación donde los participantes pudieron, a través de la transmisión de experiencias y mediante actividades concretas, conocer herramientas conceptuales y metodológicas que puedan replicar y difundir en sus respectivos países.http://promsex.org/images/docs/Publicaciones/RelatoriaIICJCosta%20Rica.pd

Lipidomics Reveals Multiple Pathway Effects of a Multi-Components Preparation on Lipid Biochemistry in ApoE*3Leiden.CETP Mice

Background: Causes and consequences of the complex changes in lipids occurring in the metabolic syndrome are only partly understood. Several interconnected processes are deteriorating, which implies that multi-target approaches might be more successful than strategies based on a limited number of surrogate markers. Preparations from Chinese Medicine (CM) systems have been handed down with documented clinical features similar as metabolic syndrome, which might help developing new intervention for metabolic syndrome. The progress in systems biology and specific animal models created possibilities to assess the effects of such preparations. Here we report the plasma and liver lipidomics results of the intervention effects of a preparation SUB885C in apolipoprotein E3 Leiden cholesteryl ester transfer protein (ApoE*3Leiden.CETP) mice. SUB885C was developed according to the principles of CM for treatment of metabolic syndrome. The cannabinoid receptor type 1 blocker rimonabant was included as a general control for the evaluation of weight and metabolic responses. Methodology/Principal Findings: ApoE*3Leiden.CETP mice with mild hypercholesterolemia were divided into SUB885C-, rimonabant- and non-treated control groups. SUB885C caused no weight loss, but significantly reduced plasma cholesterol (-49%, p <0.001), CETP levels (-31%,

Problematic internet use in Bangladeshi students: the role of socio-demographic factors, depression, anxiety, and stress

Problematic Internet Use (PIU) has become a concern for public mental health across the globe. However, there are few studies assessing PIU in Bangladesh. The present cross-sectional study estimated the prevalence rate of PIU and its associated risk factors among 405 university students in Bangladesh between June and July 2018. The measures included sociodemographic questions, internet and health-related variables, the Internet Addiction Test (IAT) and the Depression, Anxiety and Stress Scale (DASS-21). The prevalence of PIU was 32.6% among the respondents (cut-off score of ≥50 on the IAT). The prevalence of PIU was higher in males in comparison to females, although the difference was not statistically significant. Internet-related variables and psychiatric comorbidities were positively associated with PIU. From the unadjusted model, more frequent use of the internet and more time spent on the internet were identified as strong predictors of PIU, whereas the adjusted model showed depressive symptoms and stress only as strong predictors of PIU. It is hoped this preliminary study will facilitate further study on PIU along with other psychiatric disorders in Bangladesh