An Analysis of Holdings of Selected Works of Seamus Heaney from 1965 to 1995 in the University of North Carolina at Chapel Hills Rare Book Collection

The Rare Book Collection (RBC) at the University of North Carolina at Chapel Hill has a strong collection of materials of the renowned Irish poet Seamus Heaney. This paper is an analysis of selected works from the beginning of Heaney's career to when he won Nobel Prize in 1995 that are held by the RBC. It includes a brief biography of Seamus Heaney, a detailed bibliography spanning the years 1965-1995, an assessment and high spots of the collection, and a desiderata list. The paper concludes with recommendations for the future development of the collection

Computationally Modelling Cholesterol Metabolism and Atherosclerosis

Cardiovascular disease (CVD) is the leading cause of death globally. The underlying pathological driver of CVD is atherosclerosis. The primary risk factor for atherosclerosis is elevated low-density lipoprotein cholesterol (LDL-C). Dysregulation of cholesterol metabolism is synonymous with a rise in LDL-C. Due to the complexity of cholesterol metabolism and atherosclerosis mathematical models are routinely used to explore their non-trivial dynamics. Mathematical modelling has generated a wealth of useful biological insights, which have deepened our understanding of these processes. To date however, no model has been developed which fully captures how whole-body cholesterol metabolism intersects with atherosclerosis. The main reason for this is one of scale. Whole body cholesterol metabolism is defined by macroscale physiological processes, while atherosclerosis operates mainly at a microscale. This work describes how a model of cholesterol metabolism was combined with a model of atherosclerotic plaque formation. This new model is capable of reproducing the output from its parent models. Using the new model, we demonstrate how this system can be utilized to identify interventions that lower LDL-C and abrogate plaque formation

Body Composition Assessment in Masters Level Swimmers

Body composition of collegiate swimmers has been extensively studied; however, there are limited reports of body composition among Masters swimmers. This study compared the accuracy of air displacement plethysmography (ADP) and bioelectrical impedance (BIA) to the gold standard method of underwater weighing (UWW) in Masters level swimmers. The relationship between percent body fat (%BF) and body mass index (BMI) was also assessed. Recruitment (n = 6 females, 11 males) occurred at two Masters swim clubs. Pearson correlation coefficients revealed no significant differences between ADP, BIA, and UWW (p \u3e 0.05). For both female and male Masters swimmers, the mean %BF was in the healthy range (30.4 ± 11.7% female, 21.3 ± 8.0% male); however, BMI was in the overweight range (27.0 ± 7.2 kg/m2 female, 26.4 ± 4.8 kg/m2 male). These findings suggest that while ADP, BIA, and UWW were comparable methods for assessing %BF in Masters swimmers, BMI did not adequately represent body composition and health risk for Masters swimmers

The Role of Lower Leg Muscle Activity in Blood Pressure Maintenance of Older Adults

Purpose. Age-associated muscle weakness, postural instability, and orthostatic hypotension have been identified as contributing factors to falls , but the relationships among them are not clear. Therefore, the purpose of this study, a two-way factorial design, was to investigate the differences in lower extremity (LE) muscle activity, blood pressure (BP), and heart rate (HR) between young and older individuals in an upright position. Methods. Ten young males (20-24 yrs.) and 10 older males (65-82 yrs.) stood for 15 minutes while BP, HR, and LE electromyography (EMG) were recorded at one minute intervals . A two-way ANOVA was used for data analysis , p=.05. Results. Mean arterial pressure of both groups significantly increased from supine values within one minute of standing (young = 86.5±1.68 to 96.9±3.16 mmHg, old = 100.3±4.42 to 114.0±5.40 mmHg). BP variables remained elevated during the 15 minutes of standing despite a significantly attenuated HR response in the older group (young = 85±4.51 bpm, old = 73±3.98 bpm). Standing EMG activity of the older group was significantly greater than the young group. Conclusion. This study suggests that increased LE muscle activity may play a role in the ability of older individuals to maintain BP in the standing position

Coarse-graining protein energetics in sequence variables

We show that cluster expansions (CE), previously used to model solid-state materials with binary or ternary configurational disorder, can be extended to the protein design problem. We present a generalized CE framework, in which properties such as energy can be unambiguously expanded in the amino-acid sequence space. The CE coarse grains over nonsequence degrees of freedom (e.g., side-chain conformations) and thereby simplifies the problem of designing proteins, or predicting the compatibility of a sequence with a given structure, by many orders of magnitude. The CE is physically transparent, and can be evaluated through linear regression on the energies of training sequences. We show, as example, that good prediction accuracy is obtained with up to pairwise interactions for a coiled-coil backbone, and that triplet interactions are important in the energetics of a more globular zinc-finger backbone.Comment: 10 pages, 3 figure

The Story of Josie: From Involvement to Influence

This is a personal account of the author’s journey through involvement with learning communities (LCs). She began college with little exposure to mentoring and research. Six years later, she graduated with a master’s degree, a trove of experience from LCs, and the confidence to take on a research role in her profession. The author’s personal roles in LCs over the years have taken many forms, but mainly relate to the mental health of college students. LCs have served as a vehicle for launching the author’s career by helping her gain valuable experience in peer mentoring, research projects, and student poster presentations as well as providing opportunities to network, engage in professional development, and hone leadership skills. Student involvement is valuable throughout the LC experience to foster growth and development of not only the student, but the LC as well. The author witnessed firsthand the benefits of a partnership between students and LC team, demonstrating how much LCs benefit from integrating student input

Assessing Fecal Contamination in Groundwater from the Tulum Region, Quintana Roo, Mexico

The Yucatan Peninsula’s groundwater is experiencing increases in degradation due to swelling population and tourism; yet little is known about sources and transport of contaminants in drinking water supplies. The karst allows for rapid transport of microbial and chemical contaminants to the subsurface, resulting in significantly increased potential for pollution of groundwater. The objective of this research is to determine the occurrence, source, and extent of fecal con- tamination in the Tulum region of the Peninsula. A multi-analytical approach was undertaken in impacted and unim- pacted groundwater locations; measurements included physicochemical parameters, total coliform and E. coli, Bacter- oides (human vs total) and caffeine. The results indicate a variation in geochemistry from impacted to protected sites. The total coliform and E. coli show fecal contamination is wide spread. However, the presence of human Bacteriodes and caffeine in the water in the Tulum well field indicates that the recent human activities next to the well field are im- pacting the drinking water supply. This project is an assessment of the area’s current water quality conditions and the probable impact that the aforementioned growth would have on the area’s water supply. By applying multiple source parameter measurements, including molecular microbiology and chemical indicators it was confirmed the extent of fe- cal contamination of human origin covered the entire sampling region.Funding for this research was provided by Northern Illinois University’s Center for Latino and Latin American Studies, the Geology and Environmental Geosciences de- partment, and Library. This work was also funded by the United States Department of Agriculture, Agricultural Re- search Service, Water Management Conservation and Re- search Program. This article is made openly accessible in part by an award from the Northern Illinois University Libraries’ Open Access Publishing Fund

Comparison of Methods to Assess Adiposity in Middle-to-Older Adult Women

Poster from the 2015 Food & Nutrition Conference & Expo. Poster Session: Professional Skills; Nutrition Assessment; Medical Nutrition Therapy

Assessment of Cardiovascular Risk in First-Semester College Students

Poster from the 2019 Food & Nutrition Conference & Expo. Poster Session: Wellness and Public Health