22 research outputs found

    Amelia Pride Book Club of Rock Hill Records - Accession 112

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    The Amelia Pride Book Club of Rock Hill Records consist of a historical file, minutes, constitution and bylaws, correspondence, photographs, program notes, newspaper clippings, yearbooks, Winthrop publications and a scrapbook all pertaining to the origin, growth, and literary activities of the club.https://digitalcommons.winthrop.edu/manuscriptcollection_findingaids/1132/thumbnail.jp

    Relationships Between Stigma and Intimate Partner Violence Among Female Sex Workers Living with HIV in Santo Domingo, Dominican Republic

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    Background: Intimate partner violence (IPV) victimization is associated with numerous adverse health outcomes, including suboptimal HIV treatment. Violence against female sex workers (FSW) perpetrated by intimate partners outside of sex work (e.g. boyfriends or husbands) has received little attention. Stigma negatively influences economic resources, social relationships, and psychological and behavioral outcomes of the stigmatized, which may increase IPV risk. Informed by stigma, economic, and alcohol use motivation theories, I assessed relationships between HIV and sex work stigma and IPV among FSW living with HIV, including indirect effects via income, savings, and alcohol use. Methods: I analyzed cross-sectional and longitudinal survey data from a cohort of FSW living with HIV in Santo Domingo, Dominican Republic (n=266). I used multivariable logistic regression to assess relationships between enacted, anticipated, and internalized HIV and sex work stigma and recent IPV victimization (Aim 1), and path analysis to examine mediated relationships between stigma and IPV via income, savings, and alcohol use (Aim 2). Results: Participants reporting HIV-related job loss had 5.6-times the odds of IPV compared to others (95% CI: 1.9, 16.2). A higher level of fear of family exclusion due to HIV was associated with a 1.8-fold increase in IPV odds (95% CI: 1.12, 2.82), and a higher level of fear of colleagues taking your clients if you revealed your status was associated with a 1.7-fold increase in IPV odds (95% CI: 1.2, 2.6). Indirect effects were insignificant. Social HIV discrimination was negatively associated with income, and alcohol use and savings were positively associated with IPV.Conclusions: HIV stigma may undercut economic resources, social ties, and mental health, creating barriers to ending abusive relationships, or causing stress and couple conflict leading to IPV. Stigma-driven economic precarity may heighten the importance of maintaining intimate partner relationships, despite violence. Fears of family rejection may discourage HIV disclosure, diminishing social support that protects against IPV, or create a specter of isolation that hampers ending abusive relationships. Curbing workplace HIV discrimination could reduce IPV vulnerability by protecting against economic losses and precarity. Community mobilization interventions could address IPV by increasing peer support and providing the experience of supportive community.Doctor of Philosoph

    Social networks, social participation, and health among youth living in extreme poverty in rural Malawi

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    Extensive research documents that social network characteristics affect health, but knowledge of peer networks of youth in Malawi and sub-Saharan Africa is limited. We examine the networks and social participation of youth living in extreme poverty in rural Malawi, using in-depth interviews with 32 youth and caregivers. We describe youth’s peer networks and assess how gender and the context of extreme poverty influence their networks and participation, and how their networks influence health. In-school youth had larger, more interactive, and more supportive networks than out-of-school youth, and girls described less social participation and more isolation than boys. Youth exchanged social support and influence within their networks that helped cope with poverty-induced stress and sadness, and encouraged protective sexual health practices. However, poverty hampered their involvement in school, religious schools, and community organizations, directly through lack of required material means, and indirectly by reducing time and emotional resources and creating shame and stigma. Poverty alleviation policy holds promise for improving youth’s social wellbeing and mental and physical health by increasing their opportunities to form networks, receive social support, and experience positive influence

    Finishing the euchromatic sequence of the human genome

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    The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
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