The Baryonic Phase in Holographic Descriptions of the QCD Phase Diagram

We study holographic models of the QCD temperature-chemical potential phase diagram based on the D3/D7 system with chiral symmetry breaking. The baryonic phase may be included through linked D5-D7 systems. In a previous analysis of a model with a running gauge coupling a baryonic phase was shown to exist to arbitrarily large chemical potential. Here we explore this phase in a more generic phenomenological setting with a step function dilaton profile. The change in dilaton generates a linear confining $\bar{q}q$ potential and opposes the screening effect of temperature. We show that the persistence of the baryonic phase depends on the step size and that QCD-like phase diagrams can be described. The baryonic phase's existence is qualitatively linked to the existence of confinement in Wilson loop computations in the background.Comment: 21 pages, 7 figure

FIRE BEHAVIOUR IN DIFFERENT PERIODS AND CONFIGURATIONS OF A LANDSCAPE IN NORTHEASTERN PORTUGAL

Neste trabalho aborda-se a import\ue2ncia do planejamento do uso e ocupa\ue7\ue3o do solo, e do manejo dos sistemas florestais na redu\ue7\ue3o do perigo de inc\ueandio, analisando-se o comportamento do fogo em rela\ue7\ue3o \ue0s altera\ue7\uf5es na paisagem da Deil\ue3o, nordeste de Portugal. Foram utilizadas cadeias de Markov e modelos de aut\uf4matos celulares como metodologia para projetar a paisagem no futuro. FlamMap foi utilizado para simular o comportamento do fogo. De acordo com as m\ue9tricas da paisagem obtidas no Fragstats, observouse que os cen\ue1rios e proje\ue7\uf5es em Deil\ue3o t\ueam uma tend\ueancia \ue0 simplifica\ue7\ue3o da paisagem, o que pode facilitar a ocorr\ueancia de inc\ueandios maiores e mais graves. A an\ue1lise dos resultados indicou uma tend\ueancia ao aumento do perigo de inc\ueandios na regi\ue3o, em grande parte, ocasionado pela expans\ue3o de planta\ue7\uf5es cont\uednuas de florestas. Para evitar tais impactos, o manejo florestal e ordenamento da paisagem devem ser modificados a fim de se reduzir o ac\ufamulo de materiais combust\uedveis.In this study, we discuss the importance of land use, land cover planning and forest stand management in fire hazard reduction, through the analysis of fire behavior in relation to landscape changes in Deil\ue3o, northeastern Portugal. Markov chains and cellular automata model were used to project future landscapes whose structures were quantified by landscape metrics. The FlamMap model was used to simulate fire behavior. According to landscape metrics from Fragstats, we observed that scenarios and projections in Deil\ue3o have a trend towards landscape simplification, which may facilitate the occurrence of larger, more severe fires. The analyses indicate an increased fire hazard trend in the region, largely caused by the continuity of forest cover. To avoid such impacts, forest management and landscape plannig should be modified in order to reduce the accumulation of combustible materials

Strategic framework for unmanned aerial systems integration in public organisations in the Dominican Republic disaster management context

This is an accepted manuscript of an article published by Elsevier in International Journal of Disaster Risk Reduction, available online at: https://doi.org/10.1016/j.ijdrr.2021.102088 The accepted version of the publication may differ from the final published version.In the Caribbean region, there is a significant yearly number of natural events incidents. The impact of those events has affected the well-being, social and economic structures of the countries in this region. The investment in disaster management strategies is a fundamental decision to the region for improving capabilities, understanding the liabilities, dealing with the disaster stages, and integrating systems and tools to obtain greater results in resilience strategies. Therefore, information technology and robotics have played an effective role bringing innovation to the traditional approaches by improving the capabilities of personnel and serves as a catalyst to rapid data collection tools for effective decision-making during disastrous situation, as has been the case of the Dominican Republic. The organic adoption process of Unmanned Aerial System (UAS) has represented a large step forward regarding this matter. Examples of the adoption process occurs based on their flexibility in their regulatory context, funding investments in testing the applications of UAS, such as surveying, delivering medical samples and spray disinfection during the COVID-19 pandemic. However, there are only some mature applications that address a future-proofing concept as well as the integration into a typical institutional workflow. Therefore, this paper aims to be an introductory guide for decision and policymakers, educators and technicians to reduce the scepticism, lack of knowledge and know-how in the adoption of reliable, practical and effective tools by providing a combination of theories from socio-technical systems (socio-technical change impact model (SCI)) and organizational level (technology-organizational-environmental) frameworks of the UAS adoption process for natural events, tasks and critical roles in disaster management taking into account the Dominican Republic context. Qualitative cases of studies were evaluated from nine (9) professionals related to disaster management in the Dominican Republic, and a semi-structured interview were used to approach the adoption process of Unmanned Aerial System (UAS) in these organisations

Fludarabine, cytarabine, granulocyte colony-stimulating factor, and idarubicin with gemtuzumab ozogamicin improves event-free survival in younger patients with newly diagnosed aml and overall survival in patients with npm1 and flt3 mutations

Purpose To determine the optimal induction chemotherapy regimen for younger adults with newly diagnosed AML without known adverse risk cytogenetics. Patients and Methods One thousand thirty-three patients were randomly assigned to intensified (fludarabine, cytarabine, granulocyte colony-stimulating factor, and idarubicin [FLAG-Ida]) or standard (daunorubicin and Ara-C [DA]) induction chemotherapy, with one or two doses of gemtuzumab ozogamicin (GO). The primary end point was overall survival (OS). Results There was no difference in remission rate after two courses between FLAG-Ida + GO and DA + GO (complete remission [CR] + CR with incomplete hematologic recovery 93% v 91%) or in day 60 mortality (4.3% v 4.6%). There was no difference in OS (66% v 63%; P = .41); however, the risk of relapse was lower with FLAG-Ida + GO (24% v 41%; P < .001) and 3-year event-free survival was higher (57% v 45%; P < .001). In patients with an NPM1 mutation (30%), 3-year OS was significantly higher with FLAG-Ida + GO (82% v 64%; P = .005). NPM1 measurable residual disease (MRD) clearance was also greater, with 88% versus 77% becoming MRD-negative in peripheral blood after cycle 2 (P = .02). Three-year OS was also higher in patients with a FLT3 mutation (64% v 54%; P = .047). Fewer transplants were performed in patients receiving FLAG-Ida + GO (238 v 278; P = .02). There was no difference in outcome according to the number of GO doses, although NPM1 MRD clearance was higher with two doses in the DA arm. Patients with core binding factor AML treated with DA and one dose of GO had a 3-year OS of 96% with no survival benefit from FLAG-Ida + GO. Conclusion Overall, FLAG-Ida + GO significantly reduced relapse without improving OS. However, exploratory analyses show that patients with NPM1 and FLT3 mutations had substantial improvements in OS. By contrast, in patients with core binding factor AML, outcomes were excellent with DA + GO with no FLAG-Ida benefit

Systematic Approach to Engineer Decentralized Self-adaptive Systems

status: Published onlin