175 research outputs found
Creación de un corpus audiovisual para el aprendizaje de la Interpretación consecutiva
Memoria ID-0202. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2014-2015
Fully Textile-Integrated Microstrip-Fed Slot Antenna for Dedicated Short-Range Communications
Evaluación y selección de recursos web: una propuesta de calidad para la sección de referencia de la Biblioteca Universitaria de León
Se propone un método de evaluación para medir la calidad de los recursos web de referencia (diccionarios y enciclopedias) que la Biblioteca Universitaria de León ofrece en su apartado “Recursos en Internet”, dentro de la Biblioteca digital. El proyecto planteado por el Grupo de Trabajo de Recursos Electrónicos de la biblioteca, consiste en evaluar todos los recursos web incluidos en cada una de las categorías, siguiendo unos parámetros concretos, para determinar su grado de adecuación. Los resultados obtenidos tras la evaluación, nos ayudarán a seleccionar, entre la lista propuesta en un principio, aquellos materiales de referencia en formato electrónico, que sean más útiles para la comunidad universitaria, desechar aquellos que no alcancen la nota mínima exigida y recomendar otros que cumplan al cien por cien los parámetros expuesto
Evaluación y selección de recursos web: Una propuesta de calidad para la sección de referencia de la Biblioteca Universitaria de León
The purpose of this paper is to propose an evaluation method for measuring the quality of World Wide web reference resources (dictionaries and encyclopaedias) that Library of University of León make available through its Digital Library under the heading of “Resources on the internet”. The project, undertaken by the Library Working Group on Electronic Resources, consists on evaluating all web resources included in each of the mentioned categories in order to determine their suitability. The results obtained after the quality assessment, will help us to select, among the list of proposals submitted at the beginning, those electronic reference resources that are more useful for the university community members, discarding those which fail to achieve the scoring proposed and recommending other that fulfill the parameters outlined.Se propone un método de evaluación para medir la calidad de los recursos web de referencia (diccionarios y enciclopedias) que la Biblioteca Universitaria de León ofrece en su apartado “Recursos en Internet”, dentro de la Biblioteca digital. El proyecto planteado por el Grupo de Trabajo de Recursos Electrónicos de la biblioteca, consiste en evaluar todos los recursos web incluidos en cada una de las categorías, siguiendo unos parámetros concretos, para determinar su grado de adecuación. Los resultados obtenidos tras la evaluación, nos ayudarán a seleccionar, entre la lista propuesta en un principio, aquellos materiales de referencia en formato electrónico, que sean más útiles para la comunidad universitaria, desechar aquellos que no alcancen la nota mínima exigida, y recomendar otros que cumplan al cien por cien los parámetros expuestos
Experiencia de evaluación formativa en una asignatura del grado en Enfermería
pp. 375-381Se presenta la experiencia de incluir la evaluación formativa, empleada para la
competencia “aplicar el Proceso de Enfermería para proporcionar y garantizar el
bienestar, la calidad y seguridad a las personas atendidas”, que se está realizando en la
asignatura de Enfermería del Adulto, de Grado en Enfermería de la Universidad de
León, durante el curso 2016-2017. El trabajo refleja las actividades diversas y
multimétodo de los procesos de evaluación llevados a cabo, tanto a nivel de adquisición
de conocimientos, metodología científica aplicada, como en las prácticas de laboratorio.
Incluye los instrumentos utilizados y posterior evaluación de los estudiantes. Los
resultados preliminares están siendo muy positivos tanto para los profesores como para
los estudiantes y un buen reflejo de ello son los resultados del rendimiento académico
que se están obteniendo y las valoraciones positivas de los procesos de formación.S
Endothelial Progenitor Cells: Relevant Players in the Vasculopathy and Lung Fibrosis Associated with the Presence of Interstitial Lung Disease in Systemic Sclerosis Patients
Endothelial progenitor cells (EPC), which are key effectors in the physiologic vascular network, have been described as relevant players in autoimmune diseases. We previously showed that EPC frequency may help to identify the presence of interstitial lung disease (ILD) in rheumatoid arthritis patients. Given that ILD constitutes the main cause of mortality in systemic sclerosis (SSc) patients, we aimed to determine the EPC contribution to the pathogenic processes of vasculopathy and lung fibrosis in SSc-ILD+. EPC quantification was performed by flow cytometry on blood from 83 individuals: 21 SSc-ILD+ patients and subjects from comparative groups (20 SSc-ILD- and 21 idiopathic pulmonary fibrosis (IPF) patients and 21 healthy controls (HC)). EPC were considered as CD34+, CD45low, CD309+, and CD133+. A significant increase in EPC frequency was found in SSc-ILD+ patients when compared to HC (p < 0.001). SSc-ILD+ patients exhibited a higher EPC frequency than SSc-ILD- patients (p = 0.012), whereas it was markedly reduced compared to IPF patients (p < 0.001). EPC frequency was higher in males (p = 0.04) and negatively correlated to SSc duration (p = 0.04) in SSc-ILD+ patients. Our results indicate a role of EPC in the processes of vasculopathy and lung fibrosis in SSc-ILD+. EPC frequency may be considered as a biomarker of ILD in SSc patients.V.P.-C. is supported by a pre-doctoral grant from IDIVAL [PREVAL 18/01]. S.R.-M. is supported by funds from the RETICS Program [RD16/0012/0009, Instituto de Salud Carlos III (ISCIII), co-funded by the European Regional Development Fund (ERDF)]. B.A.-M. is a recipient of a ‘López Albo’ Post-Residency Programme funded by Servicio Cántabro de Salud. L.L.-G. is supported by funds from INNVAL20/06 (IDIVAL). R.P.-F. is supported by funds from the START project [FOREUM18/34]. O.G. is staff personnel of Xunta de Galicia (Servizo Galego de Saude (SERGAS) through a research-staff stabilization contract (ISCIII/SERGAS), and his work is funded by ISCIII and the ERDF [grants RD16/0012/0014 (RIER) and PI17/00409]. He is a beneficiary of project funds from the Research Executive Agency (REA) of the European Union in the framework of MSCA-RISE Action of the H2020 Programme, project 734899—Olive-Net. R.L.-M. is a recipient of a Miguel Servet type I fellowship [ISCIII, co-funded by the European Social Fund, ‘Investing in your future’, CP16/00033]
Endothelial Progenitor Cells as a Potential Biomarker in Interstitial Lung Disease Associated with Rheumatoid Arthritis
Interstitial lung disease (ILD) increases morbidity and mortality in patients with rheumatoid arthritis (RA). Although the pathogenesis of ILD associated with RA (RA-ILD+) remains poorly defined, vascular tissue is crucial in lung physiology. In this context, endothelial progenitor cells (EPC) are involved in endothelial tissue repair. However, little is known about their implication in RA-ILD+. Accordingly, we aimed to investigate the potential role of EPC related to endothelial damage in RA-ILD+. EPC quantification in peripheral blood from 80 individuals (20 RA-ILD+ patients, 25 RA-ILD? patients, 21 idiopathic pulmonary fibrosis (IPF) patients, and 14 healthy controls) was performed by flow cytometry. EPC were considered as CD34+, CD45low, CD309+ and CD133+. A significant increase in EPC frequency in RA-ILD+ patients, as well as in RA-ILD? and IPF patients, was found when compared with controls (p < 0.001, p = 0.02 and p < 0.001, respectively). RA-ILD+ patients exhibited a higher EPC frequency than the RA-ILD? ones (p = 0.003), but lower than IPF patients (p < 0.001). Our results suggest that EPC increase may represent a reparative compensatory mechanism in patients with RA-ILD+. The degree of EPC frequency may help to identify the presence of ILD in RA patients and to discriminate RA-ILD+ from IPFThis work was partially supported by the European Regional Development Fund (ERDF) and ‘Fondo de Investigación Sanitaria’ [PI18/00043] from Instituto de Salud Carlos III (ISCIII), Health Ministry, Spain. VP-C is supported by a pre-doctoral grant from IDIVAL [PREVAL 18/01]. SR-M is supported by funds of RETICS Program [RD16/0012/0009, ISCIII, co-funded by ERDF]. BA-M is a recipient of a ‘López Albo’ Post-Residency Programme funded by Servicio Cántabro de Salud. LL-G is supported by funds of ISCIII, co-funded by ERDF [PI18/00042]. OG is beneficiary of a grant funded by Xunta de Galicia, Consellería de Educación, Universidade Formación Profesional and Consellería de Economía, Emprego e Industria (GAIN), GPC IN607B2019/10. RL-M is a recipient of a Miguel Servet type I fellowship [ISCIII, co-funded by European Social Fund—ESF, CP16/00033]
Impact of regulated and emerging pollutants and microplastics in marine ecosystems (IMPACTA project)
Marine ecosystems are nowadays subjected to a massive input of synthetic chemicals from everywhere. Unfortunately only a small portion of them is being monitored, and it is necessary to identify which pollutants can produce adverse impacts in the marine environment. IMPACTA project (CTM2013-48194-C3) is characterizing the distribution of regulated and emerging contaminants and microplastics in marine sediments, and evaluating the biological effects that they can cause (sing sublethal embryotoxicity tests, endocrine disruption and biomarkers). Sensitive and selective analytical methods are being developed and validated for pharmaceuticals, perfluorinated compounds, organophosphorus pesticides, triazines, personal care products, nonylphenols and alkylated PAHs in sediments. Thus, relevant pollutants present in coastal and offshore areas will be identified. Furthermore potential toxic effects of the contaminants present in coastal sediments are being assessed through embryotoxicity bioassays and also the biological effects on different marine species as a consequence of their exposition to specific compounds.
Another relevant contribution of this project will be the assessment of the impact of micro-plastics, first time in the Spanish coastal areas. Their potential toxic effects and their role in the transference of pollutants in the marine environment are being assessed. The concentration and composition of microplastics in sediments and demersal fish stomachs are being characterized, and their potential biological effects on marine invertebrates are also being investigated
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