Isenção e equilíbrio nos diários desportivos: análise diacrónica de primeiras páginas dos jornais A Bola, Record e O Jogo (1970-2015)

Dissertação apresentada à Universidade Fernando Pessoa como parte dos requisitos para a obtenção do grau de Mestre em Ciências da Comunicação, ramo de JornalismoO presente trabalho identifica as evoluções, que se registaram no tratamento do desporto, por parte da imprensa desportiva portuguesa. Desde o ano 1970, é feita uma análise comparativa entre as principais publicações, que abordam o desporto. Numa primeira fase, apenas, o jornal desportivo A Bola e o Record e, mais tarde, o O Jogo. Estes três jornais são, hoje, uma referência no jornalismo desportivo e, ao longo dos anos, foram crescendo e evoluindo, seja através de inovações gráficas ou no tratamento do desporto, quer do futebol, quer dos outros desportos em si. Os principais objetivos, deste trabalho, são, assim, perceber qual ou quais as modalidades desportivas em que recai um maior destaque, por parte dos jornais desportivos portugueses, bem como as equipas, que, igualmente, merecem maior destaque nas primeiras páginas. Para isso, foi, então, escolhido um período de análise. Assim, a época escolhida para este estudo de caso foi o mês de abril, que, também, proporciona e exige a presença do futebol, de forma mais reforçada. A sociedade atual é, na sua maioria, uma grande consumidora de futebol e, portanto, numa altura em que, se começam a fazer contas para a conquista do título nacional, em abril, há uma, ainda, maior necessidade de divulgar o desporto nas primeiras páginas. Desta feita, uma das principais conclusões retiradas, neste trabalho, trata-se da maior presença do futebol enquanto ‘desporto-rei’. O futebol ultrapassa, assim, qualquer modalidade desportiva, no que diz respeito à presença nas primeiras páginas dos jornais desportivos. Outra conclusão importante é, também, a quantidade de notícias referentes aos três grandes clubes da I Liga portuguesa de futebol. O SL Benfica, o Sporting CP e o FC Porto são, claramente, os clubes que se destacam nas primeiras páginas destes jornais desportivos, ganhando, então, uma vantagem significativa relativamente aos restantes clubes da I Divisão e das restantes, bem como ao internacional.This paper attempts to identify the changes which occurred in the treatment of sport in the Portuguese sports press. Since 1970 there is a comparative analysis among the leading publications dealing the sport. Initially, only the sports paper A Bola, and Record and, later, O Jogo. These three newspapers are now the benchmark in sports journalism and over the years have been growing and evolving, either through graphic innovations in sport or treatment of either the football or other sports too. The main objectives of this work are realize what or which sports where lies a more prominent by the Portuguese sports papers as well as the teams that also deserve greater emphasis on the headlines. To this it was chosen an age of analysis. Thus, the period chosen for analysis was the month of April that also provides and requires the presence of football in the spotlight. Portugal is a major consumer of football and therefore at a time when they begin to reckon the champions, in April, there is an even greater need to spread the sport on the paper covers. This time, one of the main conclusions drawn in this work, it is the much greater presence of football as 'beautiful game'. Football exceeds any sport with regard to the presence it has on the covers of newspapers. Another important conclusion is also the amount of news for the three big teams of the I Liga soccer. The SL Benfica, Sporting CP and FC Porto are clearly teams that stand out on the front pages of the sports newspapers, earning then a significant advantage over other clubs of Division I and the other, as well as international

Tumor de Colisão de Odd – Dermatofibroma e Nevo

A cutaneous collision or contiguous tumor occurs when two or more cutaneous tumors coexist in a single lesion. These tumors usually have misleading clinical and histological presentations, making them a diagnostic challenge. Although several different combinations of collisions have been described we report an unusual case of a cutaneous collision tumour on the back of the patient involving an intradermal naevus and a dermatofibroma. To the best of our knowledge, this is the first time such combination is reported.Um tumor de colisão ou tumor contiguo ocorre quando dois ou mais tumores cutâneos coexistem numa lesão única. Estes tumores têm habitualmente características clinicas e histológicas atípicas, dificultando o diagnóstico. Apesar de terem sido descritas diferentes combinações de tumores de colisão, descrevemos um caso raro de um tumor de colisão localizado no dorso com associação de um nevo intradérmico a um dermatofibroma. Julgamos que se trata da primeira publicação desta combinação

Evaluation of the individual phenolic compounds of regional cultivars of pears (Pyrus communis L.) by Liquid Chromatography combined with High Resolution Mass Spectrometry

Pear (Pyrus communis L.) is a fruit of great interest because their consumption offers nutritional as well as medicinal advantages [1]. The most well-known and studied properties associated with pears are antioxidant and anti-inflammatory properties [2] these are associated with the presence of phenolic compounds, mainly in the peels but also, in smaller amounts, in its mesocarp (pulp) [3]. In this work, an Ultra-High Performance Liquid Chromatography combined with Time-of-Flight Mass Spectrometry (UHPLC-ToF-MS) method was optimized and validated for the determination of individual phenolics in the pulp and by-products of fruits. The main phenolic compounds found in the studied regional pear cultivars (6 cultivars from Alcobaça region) were catechin, epicatechin, caffeic acid, chlorogenic acid, and vanillic acid. The pear by-products (peels and seeds) presented higher phenolic content than mesocarp, mainly peels samples. One example of this is the Carapinheira Roxa cultivar, wherein the peels had the highest concentration of chlorogenic acid (26.26 ± 0.65 g/g) and lower levels were found in the seeds (3.11 ± 0.19 g/g) and in the pulp (4.27 ± 0.03 g/g). Other very well recognized pear phenolics, were quantified in all the pear cultivars, at different levels. For example, in the peels portion, the level of epicatechin varied between 0.19 g/g in the Torres Novas cultivar and 37.30 g/g in the Lambe-os-Dedos cultivar. The studied regional pear cultivars, in particular their by-products, presented high levels of phenolic compounds, showing potential to be valorized.This study was carried out in the frame of the clabel+ project: Innovative Natural, Nutritious and Consumer Oriented “Clean Label” Foods with the reference POCI-01-0247-FEDER-046080 financed by the Competitiveness and Internationalization Thematic Operational Programme (POCI), under the COMPETE2020, PORTUGAL2020 Partnership Agreement, through the co-financing of European Regional Development Fund (FEDER). The work was supported by UIDB/00211/2020 with funding from FCT/MCTES through national funds. J. D.T. would like to thank to clabel+ project for his fellowship (28/2021/BI). The authors thank Patricia Vicente for her support in the field work. C. Almeida also acknowledges the financial support by LA/P/0045/2020 (ALiCE), UIDB/00511/2020 and UIDP/00511/2020 (LEPABE), funded by national funds through FCT/MCTES (PIDDAC).info:eu-repo/semantics/publishedVersio

Antioxidant capacity and phenolics profile of portuguese traditional cultivars of apples and pears and their by-products: on the way to newer applications

Pears (Pyrus communis L.) and apples (Malus domestica Borkh.) are two of the most popular fruits worldwide. The phenolic compounds they offer are associated with human health benefits due to their antioxidant properties. Since these fruits’ by-products are not yet fully exploited, it is important to characterize them, especially in terms of their antioxidant properties. The aim of this study was to determine the antioxidant properties of old traditional cultivars, six regional pear cultivars and five regional apple cultivars grown in the Alcobaça region (Portugal). Antioxidant capacity assays were used to evaluate the antioxidant properties. Generally, the antioxidant capacity, total phenolics content (TPC), and total flavonoids content (TFC) of fruit byproducts (both seeds and peels) were higher than the corresponding mesocarp, indicating their potential as sources of beneficial antioxidant compounds. Moreover, a UHPLC-ToF-MS method was optimized and validated in order to quantify 21 distinct phenolics in these fruit samples. The analytical method’s suitability for quantifying phenolic compounds was demonstrated by an evaluation of linearity, limit of detection, limit of quantification, precision and accuracy. This method was used to determine the phenolic composition of samples of regional (local) cultivars. The phenolics in the fruit samples with the highest concentrations were phlorizin and chlorogenic acid. Principal component analysis (PCA) was used to separate distinct fruit species while emphasizing their similarities and differences.This research was funded by the clabel+ project: Innovative Natural, Nutritious and Consumer Oriented “Clean Label” Foods with the reference POCI-01-0247-FEDER-046080 financed by the Competitiveness and Internationalization Thematic Operational Programme (PO CI), under the COMPETE2020, PORTUGAL2020 Partnership Agreement, through the co-financing of European Regional Development Fund (FEDER). J.D. Teixeira is grateful for his fellowship in the frame of clabel+ project. The work was supported by UIDB/00211/2020, LA/P/0045/2020 (ALiCE), UIDB/00511/2020 and UIDP/00511/2020 (LEPABE), UIDB/04551/2020 (GREEN-IT—Bioresources for Sustainability) funded by national funds through FCT/MCTES, UIDB/04469/2020 (CEB) and by LA/P/0029/2020 (LABBELS), Centre of Chemistry (UID/QUI/0686/2020) and project BioTec Norte (operation NORTE-01-0145-FEDER-000004), supported by the Northern Portugal Regional Operational Programme (NORTE 2020), under the Portugal 2020 Partnership Agreement, through the European Regional Development Fund (ERDF)

The impact of imprisonment on individuals’ mental health and society reintegration: study protocol

Background Prison sentences are a particular type of penalty that aim to reintegrate individuals into society. Nonetheless, research suggests that prison sentences have a null or a criminogenic effect on recidivism and a critical impact on inmates’ mental health, negatively interfering with their successful reintegration into society and recidivism. Prevalence rates of mental health disorders among individuals who commit crimes are high, but little is known about how incarceration perpetuates and/or worsens mental health symptoms. In the Portuguese context, no studies focused on understanding the impact of imprisonment on prisoners’ mental health. Thus, this project aims to understand incarceration’s mental health and well-being impact on male and female individuals convicted to prison, both while incarcerated and after release. Methods The study will follow a quantitative cross-sectional design of male and female individuals in prison and parole, aiming to assess different samples at different moments of the prison sentence. It will also follow a longitudinal design in a subsample of male and female individuals sentenced to prison and on parole who will be followed for one year. Discussion This study intends to have a meaningful impact on the understanding of imprisonment effects, giving important clues for developing and implementing evidence-based prevention and intervention strategies to address prisoners’ and ex-prisoners’ mental health and improve their ability to successfully reintegrate into society and reduce recidivism.This work was funded by the Foundation for Science and Technology – FCT (Portuguese Ministry of Science, Technology and Higher Education), under the grant UIDB/05380/2020

Medicine on the work of Amadeo de Souza-Cardoso

Copyright © Ordem dos Médicos 2014Amadeo de Souza-Cardoso, one of the pivotal figures of the Portuguese Modernist movement, studied painting and began his work in Paris where he arrived at the age of 19. Interestingly, Amadeo cemented strong friendships with some physicians from his time. The first was Manuel Laranjeiro, physician, poet and essayist, who has been a major influence on his choice of studying visual arts. In 1909, the painter met the dermatologist Paul Alexander and later Dr. Martins, who diagnosed him with a dermatosis, which led the painter to have to interrupt his work. Described as an eczema, which affected his face and hands, probably an allergic contact dermatitis to paints or other products that did not become clarified, with the artist's early death at age of 30 by pneumonic fever. Occupational diseases affect the practice of many professions and artists, including painters, who constitute an important risk group. Contact with several components of paints and solvents are associated with the contact sensitization. However, allergens responsible for allergic contact dermatitis change over the time according to the usage trends and products' composition.Amadeo de Souza-Cardoso (1887-1918), vulto do movimento do Modernismo em Portugal, estudou e iniciou a sua obra em Paris para onde partiu aos 19 anos de idade. Curiosamente, Amadeo consolidou fortes relações de amizade ao longo da sua vida com alguns médicos, seus contemporâneos. O primeiro foi Manuel Laranjeira, médico, poeta e ensaísta, que terá sido determinante na escolha do caminho dos estudos artísticos aos 17 anos de idade. Em 1909, contactou com o dermatologista Paul Alexander e posteriormente o Dr. Martins, que acompanhou o pintor nas Termas das Taipas, por uma dermatose que o impediu de pintar nos últimos tempos de vida. Descrita como um eczema que comprometia as mãos e a face, provavelmente uma dermite de contacto alérgica a tintas ou outros produtos que não chegou a ser esclarecida, com a morte precoce do artista aos 30 anos por ‘febre pneumónica’. As doenças profis-sionais comprometem a prática de muitas profissões e os artistas plásticos, nomeadamente os pintores, constituem um dos grupos de risco. O contacto com diversos componentes de tintas, diluentes e produtos de limpeza está associado à sensibilização por contacto e os alergenos responsáveis por dermites de contacto alérgicas vão mudando, de acordo com os padrões de utilização e composição dos produtos.info:eu-repo/semantics/publishedVersio

Infliximab therapy for Netherton syndrome: a case report

© 2017 by the American Academy of Dermatology, Inc. Published by Elsevier, Inc. This is an open access article under the CC BY- NC-ND license (http://creativecommons.org/licenses/by-nc-nd/ 4.0/).A 19-year-old white woman was referred to our outpatient dermatology clinic with an undiagnosed skin eruption since early childhood. She was born from normal delivery after an uneventful pregnancy from healthy nonconsanguineous parents and did not present any cutaneous lesions at birth. Her sister has a similar dermatosis, which also appeared during childhood.info:eu-repo/semantics/publishedVersio

O Impacto do Campo de Cancerização no Desenvolvimento de Cancro Cutâneo

The concept of field cancerization, described in various types of cancer, has been intensely studied in skin cancer. It can be defined as the process in which the cells in a tissue or organ are transformed, with genetic modifications, but with normal clinical and histologic features, prior to neoplastic development or coexisting with malignant cells, independently of clonality. Applying this concept to clinical practice could have potentially important implications in early diagnosis, risk stratification, primary and secondary chemoprevention, definition of resection margins, and approach to local and distance recurrences. This paper presents a literature review on the concept of field cancerization, with emphasis on the potential implications for daily clinical practice.O conceito de campo cancerização, descrito em vários tipos de cancro, tem sido investigado de forma cada vez mais aprofundada no cancro cutâneo, podendo ser definido como o processo em que as células num determinado tecido ou órgão estão transformadas, com alterações genéticas, mas de aspeto clínico e histológico normal, numa fase prévia ao desenvolvimento de neoplasia ou coexistindo com células malignas, independentemente da clonalidade. A aplicação deste conceito na prática clínica poderá ter implicações potencialmente importantes no diagnóstico precoce, na estratificação de risco, na quimioprevenção primária e secundária, na definição de margens tumorais para tratamento e na abordagem das recidivas locais ou à distância. Este artigo apresenta uma revisão da literatura no que respeita ao conceito de campo de cancerização, destacando as suas implicações na prática clínica diária

PIGMENTED VULVAR BASAL CELL CARCINOMA – RELEVANCE OF THE DIFFERENTIAL DIAGNOSIS IN OTHER PIGMENTED VULVAR LESIONS

Introdução: Os basaliomas são os tumores malignos mais frequentemente encontrados na raça humana e com uma incidência cada vez maior nas últimas décadas. Neste tipo de neoplasias, a vulva é uma localização atípica, provavelmente porque os fatores etiológicos são diferentes dos de outras áreas anatómicas. Têm uma clínica monótona e inespecífica. Caso Clínico: Mulher de 69 anos, que surge com uma placa erosionada com cerca de 3cm de eixo maior, fundo duro com pequenas áreas pigmentadas na periferia do grande lábio direito. A histologia revelou tratar-se de um basalioma pigmentado. Foi submetida a exérese cirúrgica alargada da lesão, não se tendo verificado recidiva após três anos de seguimento. Conclusão: Os basaliomas pigmentados da vulva são muito raros. Salienta-se a importância do diagnóstico diferencial com outras lesões pigmentadas nesta região, que podem ser neoplasias de maior gravidade, que requerem outros tratamentos mais invasivos. Como a taxa de recidiva dos basaliomas é elevada o seguimento periódico é obrigatório. PALAVRAS-CHAVE – Basaliomas; Neoplasias da pele; Neoplasias da vulva. Introduction: Basal cell carcinoma is the most common malignant tumors found in the human race, with an increasing incidence in recent decades. The vulva is an atypical location for this type of neoplasm, probably because the etiological factors are different from other anatomical areas. It has a non-specific and monotonous symptomatology. Case Report: A 69-year-old woman attended with a 3cm eroded plaque with small pigmented areas on the edge of the right labia majora. Histology revealed a pigmented basal cell carcinoma. The patient underwent to wide excision. After three years of follow-up there was no recurrence. Conclusion: Pigmented vulva basal cell carcinoma is a rarity. We emphasize how important is the differential diagnosis with other pigmented lesions in this area which may be neoplasm with a worst prognosis and require other kind of treatments. Periodic follow-up is required because the high rate of recurrence. KEYWORDS – Pigmentation disorders; Skin neoplasms; Vulvar neoplasms.