Validation of a knee angle measurement system based on imus

Inertial Measurements Unit (IMU) based systems are a purposeful and alternative tool to monitor human gait mainly because they are cheaper, smaller and can be used without space restrictions compared to other gait analysis methods. In the scientific community, there are well-known studies that test the accuracy and efficiency of this method compared to ground truth systems. Gait parameters such as stride length, distance, velocity, cadence, gait phases duration and detection, or joint angles are tested and validated in these studies in order to study and improve this technology. In this article, knee joint angles were calculated from IMUs’ data and they were compared with DARwIn OP knee joint angles. IMUs were attached to the left leg of the robot and left knee flexion-extension (F-E) was evaluated. The RMSE values were less than 6 when DARwIn OP was walking, and less than 5 when the robot kept the left leg stretched and performed an angle of-30 . ◦ ◦ ◦This work is supported by the FCT Fundação para a Ciência e Tecnologia - with the scholarship reference SFRH/BD/102659/2014, the reference project UID/EEA/04436/2013, by FEDER funds through the COM PETE 2020 - Programa Operacional Competitividade e Internacionalização (POCI) - with the reference project POCI-01-0145-FEDER-006941; and the LIACC Project PEst/UID/CEC/00027/2015

In-season microcycle quantification of professional women soccer players—external, internal and wellness measures

Although data currently exists pertaining to the intensity in the women’s football match, the knowledge about training is still scarce. Therefore, the aim of this study was to quantify external (locomotor activity) and internal (psychophysiological) intensities, as well as the wellness profile of the typical microcycle from professional female soccer players during the 2019/20 in-season. Ten players (24.6 ± 2.3 years) from an elite Portuguese women soccer team participated in this study. All variables were collected in 87 training session and 15 matches for analysis from the 2019–2020 in-season. Global positioning variables such total distance, high-speed running, acceleration, deceleration and player load were recorded as intensity while Rated Perceived Exertion (RPE) and session-RPE were recorded as internal measures. The Hooper Index (HI) was collected as a wellness parameter. The results showed that internal and external intensity measures were greater in matches compared to trainings during the week (match day minus [MD-], MD-5, MD-4, MD-2), p < 0.05 with very large effect size (ES). In the same line, higher internal and external intensity values were found in the beginning of the week while the lowest values were found in MD-2 (p < 0.05, with very large ES). Regarding wellness, there was no significant differences in the HI parameters between the training days and match days (p > 0.05). This study confirmed the highest intensity values during MD and the lowest on the training session before the MD (MD-2). Moreover, higher training intensities were found in the beginning of the training week sessions which were then reduced when the MD came close. Wellness parameters showed no variation when compared to intensity measures. This study confirmed the hypothesis regarding internal and external intensity but not regarding wellness.info:eu-repo/semantics/publishedVersio

Different infective forms trigger distinct immune response in experimental Chagas disease.

Although metacyclic and blood trypomastigotes are completely functional in relation to parasite-host interaction and/or target cell invasion, they differ in the molecules present on the surface. Thus, aspects related to the variability that the forms of T. cruzi interacts with host cells may lead to fundamental implications on the immune response against this parasite and, consequently, the clinical evolution of Chagas disease. We have shown that BT infected mice presented higher levels of parasitemia during all the acute phase of infection. Moreover, the infection with either MT or BT forms resulted in increased levels of total leukocytes, monocytes and lymphocytes, specifically later for MT and earlier for BT. The infection with BT forms presented earlier production of proinflammatory cytokine TNF-α and later of IFN-γ by both T cells subpopulations. This event was accompanied by an early cardiac inflammation with an exacerbation of this process at the end of the acute phase. On the other hand, infection with MT forms result in an early production of IFN-γ, with subsequent control in the production of this cytokine by IL-10, which provided to these animals an immunomodulatory profile in the end of the acute phase. These results are in agreement with what was found for cardiac inflammation where animals infected with MT forms showed intense cardiac inflammation later at infection, with a decrease in the same at the end of this phase. In summary, our findings emphasize the importance of taking into account the inoculums source of T. cruzi, since vectorial or transfusional routes of T. cruzi infection may trigger distinct parasite-host interactions during the acute phase that may influence relevant biological aspects of chronic Chagas disease

In-Season Internal Load and Wellness Variations in Professional Women Soccer Players: Comparisons between Playing Positions and Status

The internal intensity monitoring in soccer has been used more in recent years in men’s football; however, in women’s soccer, the existing literature is still scarce. The aims of this study were threefold: (a) to describe the weekly variations of training monotony, training strain and acute: chronic workload ratio through session Rated Perceived Exertion (s-RPE); (b) to describe weekly variations of Hooper Index [stress, fatigue, Delayed Onset Muscle Soreness (DOMS) and sleep]; and (c) to compare those variations between playing positions and player status. Nineteen players (24.1 ± 2.7 years) from a Portuguese BPI League professional team participated in this study. All variables were collected in a 10-week in-season period with three training sessions and one match per week during the 2019/20 season. Considering the overall team, the results showed that there were some associations between Hooper Index categories and s-RPE like stress or fatigue (0.693, p < 0.01), stress or DOMS (0.593, p < 0.01), stress or s-RPE (−0.516, p < 0.05) and fatigue or DOMS (0.688, p < 0.01). There were no differences between all parameters in playing positions or player status. In conclusion, the study revealed that higher levels of fatigue and DOMS occur concurrently with better nights of sleep. Moreover, any in-season variations concerning internal load and perceived wellness seems independent of position or status in outfield players. The data also showed that the higher the players’ reported stress, the lower the observed s-RPE, thus possibly indicating a mutual interference of experienced stress levels on the assimilation of training intensity by elite women soccer players.Portuguese Foundation for Science and Technology, I.P., Grant/Award Number UIDP/04748/2020FCT–Fundação para a Ciência e Tecnologia (UID04045/2020)Fundação para a Ciência e Tecnologia/ Ministério da Ciência, Tecnologia e Ensino Superior through national funds and when applicable co-funded EU funds under the project UIDB/50008/202

Supervisão clínica de alunos de enfermagem

info:eu-repo/semantics/publishedVersio

Bilateral occipital calcification, epilepsy and coeliac disease: case report

We report a case of a six-year-old girl with frequent diarrhea episodes associated with ferroprive anemia from 6 months of age, normal neuromotor development and partial seizures initiated in her 3rd year which was controlled with carbamazepine. CT scan in her 5th year of age demonstrated gyral calcifications in the occipital and posterior parietal regions bilaterally. MRI has shown low signal areas in the axial T2 sequences corresponding to the gyral calcifications evident on the CT. Blood investigation for coeliac disease with antigliadin, endomysial and transglutaminase antibodies was positive and the intestinal biopsy has showed villous atrophy associated with an increased number of intraepithelial lymphocytes and hypertrophic criptae compatible with coeliac disease.Relatamos o caso de uma menina com 6 anos de idade que apresentava episódios recorrentes de diarréia desde os 6 meses de vida associada a anemia ferropriva com desenvolvimento neuromotor normal. Aos 3 anos de idade começou a apresentar crises parciais que foram controladas com carbamazepina. Tomografia computadorizada de crânio aos 5 anos demonstrou calcificações girais grosseiras nas regiões occipital e parietal posterior bilateralmente. A ressonância magnética de crânio evidenciou áreas de hipossinal em T2 na região parieto-occipital bilateralmente. Realizou investigação para síndrome de mal absorção incluindo estudo da função digestivo/absortiva (teste D-xilose), avaliação sorológica (anticorpos antigliadina, antiendomísio e antitransglutaminase) e biopsia de intestino delgado que demonstrou intensa atrofia de vilosidades com infiltrado linfoplasmocitário no córion compatível com doença celíaca.Universidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Setor de Neurologia InfantilUniversidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Departamento de PatologiaUNIFESP, EPM, Setor de Neurologia InfantilUNIFESP, EPM, Depto. de PatologiaSciEL

Tecnologias Informacionais e Comunicacionais no Ensino de Matemática: a produção de atividades investigativas num curso de Mestrado Profissional em Educação Matemática.

O presente trabalho traz uma reflexão sobre a utilização de Tecnologias Informacionais e Comunicacionais no ensino de Matemática como uma tendência de pesquisa e prática em Educação Matemática que implica numa mudança do cenário atual da sala de aula e do papel de seus principais atores: o professor, que passa a ser um mediador na construção do ensino, e os alunos, que devem assumir uma postura de agentes ativos na construção de seu conhecimento. A seguir, apresentamos atividades investigativas elaboradas e testadas por alunos do Mestrado Profissional em Educação Matemática da Universidade Federal de Ouro Preto, envolvendo alguns conteúdos de Geometria e Álgebra trabalhados nos Ensinos Fundamental e Médio, sob a forma de seqüências para a sala de aula que podem ser utilizadas por Professores de Matemática. Com isso, buscamos contribuir para o desenvolvimento profissional desses docentes e destacar o papel das tecnologias na sala de aula de Matemática, redirecionando o seu processo de ensino, visando uma aprendizagem significativa