Predictive complication factors for ct‐guided fine needle aspiration biopsy of pulmonary lesions

OBJECTIVE: Distinct aspects can influence the complication rates of computed tomography-guided percutaneous fine needle aspiration biopsy of lung lesions. The purpose of the current study is to determine the influence of radiological techniques and clinical characteristics in predicting complications from this procedure. SUBJECTS AND METHODS: A retrospective study was developed involving 340 patients who were submitted to a consecutive series of 362 computed tomography-guided fine needle aspiration biopsies of lung lesions between July 1996 and June 2004, using 22-gauge needles (CHIBA). Variables such as the radiological characteristics of the lesions, secondary pulmonary radiological findings, co-morbidities, and aspects concerning the procedure were studied. RESULTS: The diameters of the lung lesions varied from 9 to 140 mm, with a mean of 51.5 ± 24.3 mm and median of 40mm. The depth of the lesions varied from 10 mm to 130 mm, with a mean of 44 ± 20.9mm, and median median of 52 mm. Complications occurred in 52 (14.4%) cases, pneumothorax being the most frequent, with 40 (11.1%) cases, followed by hemoptisis with 7 (1.9%) cases, and hematoma with 4 (1.1%) cases. Lesions that did not contact the pleura, with normal pulmonary tissue interposition between lesion and pleura, had higher complication rates, with 22 (22%) cases, than lesions that contact the pleura, with 6 (9%) cases, with a statistically significant difference (p = 0.03). CONCLUSIONS: CT-guided percutaneous fine needle aspiration biopsy of lung lesions had a lower rate of complications in our study and presented more rates of complications on lesions that lack pleural contact

Predictive complication factors for ct-guided fine needle aspiration biopsy of pulmonary lesions

OBJECTIVE: Distinct aspects can influence the complication rates of computed tomography-guided percutaneous fine needle aspiration biopsy of lung lesions. The purpose of the current study is to determine the influence of radiological techniques and clinical characteristics in predicting complications from this procedure. SUBJECTS AND METHODS: A retrospective study was developed involving 340 patients who were submitted to a consecutive series of 362 computed tomography-guided fine needle aspiration biopsies of lung lesions between July 1996 and June 2004, using 22-gauge needles (CHIBA). Variables such as the radiological characteristics of the lesions, secondary pulmonary radiological findings, co-morbidities, and aspects concerning the procedure were studied. RESULTS: The diameters of the lung lesions varied from 9 to 140 mm, with a mean of 51.5 ± 24.3 mm and median of 40mm. The depth of the lesions varied from 10 mm to 130 mm, with a mean of 44 ± 20.9mm, and median median of 52 mm. Complications occurred in 52 (14.4%) cases, pneumothorax being the most frequent, with 40 (11.1%) cases, followed by hemoptisis with 7 (1.9%) cases, and hematoma with 4 (1.1%) cases. Lesions that did not contact the pleura, with normal pulmonary tissue interposition between lesion and pleura, had higher complication rates, with 22 (22%) cases, than lesions that contact the pleura, with 6 (9%) cases, with a statistically significant difference (p = 0.03). CONCLUSIONS: CT-guided percutaneous fine needle aspiration biopsy of lung lesions had a lower rate of complications in our study and presented more rates of complications on lesions that lack pleural contact

Ranking contrasting genotypes of forage peanut based on nutritive value and fermentation kinetics

AbstractThe objective of this study was to evaluate the nutritional divergence of perennial peanut genotypes through chemical characteristics as well as in vitro fermentation and degradation kinetics. The experiment was conducted at The Brazilian Agricultural Research Corporation (Embrapa Cerrados). The treatments consisted of 10 accessions of Arachis spp., 6 accessions of A. pintoi (Ap 8, Ap 19, Ap 20, Ap 24, Ap 31, Ap 65) and the cultivar Belmonte, 2 accessions of Arachis repens (Ar 5, Ar 26) and an interspecific hybrid (Ap×Ar) 9. The experimental design was a completely randomised block with four replications. Forage evaluations were made at a stubble height of 5cm from the soil surface with fixed cutting intervals of 42 days during the rainy season. Nutritional divergence was assessed using canonical variate analysis and hierarchical agglomerative clustering including the variables crude protein, neutral detergent fibre, lignin(sa), potential DM degradation at 48h, the insoluble but potentially degradable DM fraction and the degradation rate of the insoluble but potentially degradable DM fraction. Variables with higher contribution to discrimination of accessions were: rate of degradation, crude protein and potential DM degradation at 48h. Four distinct nutritional groups were identified: Group I (Ap 8, Ap 19, Ap 31, cv. Belmonte), Group II (Ap 20, Ap 24, Ap 65), Group III (Ar 5. Ar 26) and Ggroup IV (Ap×Ar 9). The nutritional divergence of the Arachis evaluated show great variability relative to the parameters analysed, which may impact genetic improvement programs which focus on chemical composition and in vitro fermentation characteristics. Group IV (hybrid Ap×Ar 9) had the highest nutritional quality as ruminant feeds

Hearing preservation and cochlear implants according to inner ear approach: multicentric evaluation

AbstractIntroductionElectroacoustic stimulation is an excellent option for people with residual hearing in the low frequencies, who obtain insufficient benefit with hearing aids. To be effective, the subject's residual hearing should be preserved during cochlear implant surgery.ObjectivesTo evaluate the hearing preservation in patients that underwent implant placement and to compare the results in accordance with the approach to the inner ear.Methods19 subjects underwent a soft surgical technique, and the electrode MED-EL FLEX™ EAS, designed to be atraumatic, was used. We evaluated pre- and postoperative tonal audiometric tests with an average of 18.4 months after implantation, to measure the rate of hearing preservation.Results17 patients had total or partial preservation of residual hearing; 5 had total hearing preservation and two individuals had no preservation of hearing. The insertion of the electrode occurred through a cochleostomy in 3 patients, and in 2 of these there was no hearing preservation; the other 16 patients experienced electrode insertion through a round window approach. All patients benefited from the cochlear implant, even those who are only using electrical stimulation.ConclusionThe hearing preservation occurred in 89.4% of cases. There was no significant difference between the forms of inner ear approach

Infestação de Diatraea spp. (LEPIDOPTERA: CRAMBIDAE) em variedades RB (República do Brasil) de cana-de-açúcar

O objetivo deste trabalho foi avaliar o comportamento de variedades RB (República do Brasil) de cana-de-açúcar em relação ao ataque de Diatraea spp. Foram utilizados os sistemas de cultivo de sequeiro e irrigado. As variedades estudadas foram: RB72454, RB867515, RB971755, RB951541, RB931003, RB92579, RB863129 e RB93509. Para o cultivo irrigado, incluiu-se a RB98710. As avaliações da porcentagem de intensidade de dano interno foram realizadas por ocasião da colheita, em 15 colmos de cada parcela. Todos os colmos foram abertos no sentido longitudinal, obtendo-se assim a porcentagem de entrenós danificados pelo complexo broca/podridão. As médias foram comparadas pelo teste de Tukey a 5% de probabilidade. No primeiro ano de avaliação, no cultivo de sequeiro, a variedade RB971755 apresentou maior média de infestação de Diatraea spp. quando comparada com as demais variedades. No segundo ano a variedade RB931003 foi a mais atacada pela praga e nos dois anos subsequentes as variedades não diferiram entre si em relação ao ataque da praga. No cultivo irrigado, em cana planta, a variedade RB867515 apresentou maior infestação por Diatraea spp. e nos dois anos seguintes não houve diferenças significativas entre as variedades testadas. Em ambos os sistemas de cultivo, houve um decréscimo na produtividade da cultura durante as avaliações anuais. Os valores de % de infestação não apresentaram correlações significativas com os parâmetros agroindustriais avaliados em ambos os sistemas de cultivo. Infestation OF Diatraea spp. (Lepidoptera: Crambidae) in varieties of sugar caneAbstractThe aim of this study was to evaluate the variation of infestation Diatraea spp. in different varietiesRB (Republic of Brazil) of cane sugar in cropping systems for dryland and irrigated four and threeyears, respectively. The varieties studied were as follows: RB72454, RB867515, RB971755, RB951541,RB931003, RB92579, RB863129 and RB93509. For the irrigated system, the variety RB98710 was alsoincluded. Assessments of the percentage of intensity of internal damage were carried out at harvest,in 15 stalks in each plot. All stalks were opened longitudinally, thus obtaining the percentage ofinternodes damaged by the complex borer/rottenness. The results were submitted to analysis ofvariance and means were compared by Tukey test at 5% probability. In the first year of assessment,in rainfed crop, the variety RB971755 showed the highest average of infestation by Diatraea spp.when compared with all other varieties. In the second year the variety RB931003 was the mostattacked by the pest and for the subsequent two years the varieties did not differ in relation topest attack. In the first year, for the irrigated system, the most infested variety was RB867515. In thefollowing two years it was not possible to identify a variety with striking characteristic of preferenceby the sugar cane borer. In both systems, there was a decrease in crop productivity during annualassessment. The values of % infestation showed no significant correlations with the agroindustrialparameters evaluated in the two systems of cultivation

Linear Epidermal Nevus Of The Oral Cavity: A Rare Diagnosis.

Linear epidermal nevus is an uncommon diagnosis of benign lesions of the oral cavity. It is characterized by a congenital malformation arising from the ectoderm cells, which are arranged according to a typical linear configuration known as Blaschko's lines. We report a case of linear epidermal nevus of oral cavity in a 51-year-old lady or woman. The linear epidermal nevus of the oral cavity, although rare, can be considered a differential diagnosis of oral papillomatosis (OP). The histopathological studies and detailed description are the center of the diagnostic and clinical evolution.201220683

Efeito de três formulações de Bacillus amyloliquefaciens ICBB200 sobre o crescimento de plantas de alface (Lactuca sativa L.) em cinco condições edafoclimáticas

Conventional vegetable production is based on the use of chemical fertilizers and pesticides, which contribute to increased food production. However, excessive and inappropriate use of these products can cause several problems to health and the environment. The use of bacteria promoting plant growth, such Bacillus amyloliquefaciens ICBB200 is an alternative, since they act directly on the plant growth due to changes in hormonal levels and increased intake of nutrients such as phosphorus and iron, and also act indirectly by suppressing diseases. Field tests with three different formulations of B. amyloliquefaciens ICBB200 were conducted in lettuce growing areas, in five different soils and climatic conditions in the city of Porto Alegre, Rio Grande do Sul State. After 34 days of cultivation, the plants were collected and evaluated for circumference and fresh weight of aerial part. B. amyloliquefaciens ICBB200 promoted shoot growth of lettuce plants in any of their formulations tested, at all the different conditions tested.A produção convencional de hortaliças se baseia no uso de fertilizantes e defensivos químicos, os quais contribuem para o aumento da produção de alimentos. Porém, o uso exagerado e inadequado desses produtos pode causar vários problemas à saúde e ao meio ambiente. O uso de bactérias promotoras de crescimento de plantas, como Bacillus amyloliquefaciens, surge como uma alternativa, já que as mesmas atuam diretamente no crescimento vegetal por alterações nas concentrações hormonais e maior aporte de nutrientes, como nitrogênio, fósforo e ferro, além de também atuar indiretamente pela supressão de doenças. Com isso, este trabalho objetiva avaliar o efeito da bactéria B. amyloliquefaciens ICBB200, apresentada em três diferentes formulações, sobre o crescimento de plantas de alface, em cinco condições edafoclimáticas diferentes. Ensaios em campo com três diferentes formulações de B. amyloliquefaciens ICBB200 foram conduzidos em áreas de cultivo de alface, em cinco condições edafoclimáticas distintas, na cidade de Porto Alegre, RS. Após 34 dias de cultivo, as plantas foram coletadas e avaliadas quanto à circunferência e peso de massa fresca de parte aérea. B. amyloliquefaciens ICBB200 promoveu o crescimento de parte aérea de plantas de alface, em qualquer uma de suas formulações testadas, em todas diferentes condições edafoclimáticas testadas

Effect of three formulations of Bacillus amyloliquefaciens ICBB200 on lettuce growth (Lactuca sativa L.) in five soil and climate conditions

A produção convencional de hortaliças se baseia no uso de fertilizantes e defensivos químicos, os quais contribuem para o aumento da produção de alimentos. Porém, o uso exagerado e inadequado desses produtos pode causar vários problemas à saúde e ao meio ambiente. O uso de bactérias promotoras de crescimento de plantas, como Bacillus amyloliquefaciens, surge como uma alternativa, já que as mesmas atuam diretamente no crescimento vegetal por alterações nas concentrações hormonais e maior aporte de nutrientes, como nitrogênio, fósforo e ferro, além de também atuar indiretamente pela supressão de doenças. Com isso, este trabalho objetiva avaliar o efeito da bactéria B. amyloliquefaciens ICBB200, apresentada em três diferentes formulações, sobre o crescimento de plantas de alface, em cinco condições edafoclimáticas diferentes. Ensaios em campo com três diferentes formulações de B. amyloliquefaciens ICBB200 foram conduzidos em áreas de cultivo de alface, em cinco condições edafoclimáticas distintas, na cidade de Porto Alegre, RS. Após 34 dias de cultivo, as plantas foram coletadas e avaliadas quanto à circunferência e peso de massa fresca de parte aérea. B. amyloliquefaciens ICBB200 promoveu o crescimento de parte aérea de plantas de alface, em qualquer uma de suas formulações testadas, em todas diferentes condições edafoclimáticas testadas.Conventional vegetable production is based on the use of chemical fertilizers and pesticides, which contribute to increased food production. However, excessive and inappropriate use of these products can cause several problems to health and the environment. The use of bacteria promoting plant growth, such Bacillus amyloliquefaciens ICBB200 is an alternative, since they act directly on the plant growth due to changes in hormonal levels and increased intake of nutrients such as phosphorus and iron, and also act indirectly by suppressing diseases. Field tests with three different formulations of B. amyloliquefaciens ICBB200 were conducted in lettuce growing areas, in five different soils and climatic conditions in the city of Porto Alegre, Rio Grande do Sul State. After 34 days of cultivation, the plants were collected and evaluated for circumference and fresh weight of aerial part. B. amyloliquefaciens ICBB200 promoted shoot growth of lettuce plants in any of their formulations tested, at all the different conditions tested

Alcohol Abuse Promotes Changes in Non-Synaptic Epileptiform Activity with Concomitant Expression Changes in Cotransporters and Glial Cells

Non-synaptic mechanisms are being considered the common factor of brain damage in status epilepticus and alcohol intoxication. the present work reports the influence of the chronic use of ethanol on epileptic processes sustained by non-synaptic mechanisms. Adult male Wistar rats administered with ethanol (1, 2 e 3 g/kg/d) during 28 days were compared with Control. Non-synaptic epileptiform activities (NEAs) were induced by means of the zero-calcium and high-potassium model using hippocampal slices. the observed involvement of the dentate gyrus (DG) on the neurodegeneration promoted by ethanol motivated the monitoring of the electrophysiological activity in this region. the DG regions were analyzed for the presence of NKCC1, KCC2, GFAP and CD11b immunoreactivity and cell density. the treated groups showed extracellular potential measured at the granular layer with increased DC shift and population spikes (PS), which was remarkable for the group E1. the latencies to the NEAs onset were more prominent also for the treated groups, being correlated with the neuronal loss. in line with these findings were the predispositions of the treated slices for neuronal edema after NEAs induction, suggesting that restrict inter-cell space counteracts the neuronal loss and subsists the hyper-synchronism. the significant increase of the expressions of NKCC1 and CD11b for the treated groups confirms the existence of conditions favorable to the observed edematous necrosis. the data suggest that the ethanol consumption promotes changes on the non-synaptic mechanisms modulating the NEAs. for the lower ethanol dosage the neurophysiological changes were more effective suggesting to be due to the less intense neurodegenertation.Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Univ Fed Sao Joao del Rei, Dept Engn Biossistemas, Lab Neurociencia Expt & Computac, Sao Joao Del Rei, MG, BrazilUniversidade Federal de São Paulo, Escola Paulista Med, Disciplina Neurol Expt, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Ciencia & Tecnol, Sao Jose Dos Campos, SP, BrazilUniversidade Federal de São Paulo, Escola Paulista Med, Disciplina Fisiol, São Paulo, BrazilUniversidade Federal de São Paulo, Escola Paulista Med, Disciplina Neurol Expt, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Ciencia & Tecnol, Sao Jose Dos Campos, SP, BrazilUniversidade Federal de São Paulo, Escola Paulista Med, Disciplina Fisiol, São Paulo, BrazilWeb of Scienc