53 research outputs found
Sample-based motion planning in high-dimensional and differentially-constrained systems
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2010.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Cataloged from student submitted PDF version of thesis.Includes bibliographical references (p. 115-124).State of the art sample-based path planning algorithms, such as the Rapidly-exploring Random Tree (RRT), have proven to be effective in path planning for systems subject to complex kinematic and geometric constraints. The performance of these algorithms, however, degrade as the dimension of the system increases. Furthermore, sample-based planners rely on distance metrics which do not work well when the system has differential constraints. Such constraints are particularly challenging in systems with non-holonomic and underactuated dynamics. This thesis develops two intelligent sampling strategies to help guide the search process. To reduce sensitivity to dimension, sampling can be done in a low-dimensional task space rather than in the high-dimensional state space. Altering the sampling strategy in this way creates a Voronoi Bias in task space, which helps to guide the search, while the RRT continues to verify trajectory feasibility in the full state space. Fast path planning is demonstrated using this approach on a 1500-link manipulator. To enable task-space biasing for underactuated systems, a hierarchical task space controller is developed by utilizing partial feedback linearization. Another sampling strategy is also presented, where the local reachability of the tree is approximated, and used to bias the search, for systems subject to differential constraints. Reachability guidance is shown to improve search performance of the RRT by an order of magnitude when planning on a pendulum and non-holonomic car. The ideas of task-space biasing and reachability guidance are then combined for demonstration of a motion planning algorithm implemented on LittleDog, a quadruped robot. The motion planning algorithm successfully planned bounding trajectories over extremely rough terrain.by Alexander C. Shkolnik.Ph.D
Adaptive Response to DNA-Damaging Agents in Natural Saccharomyces cerevisiae Populations from “Evolution Canyon”, Mt. Carmel, Israel
BACKGROUND:Natural populations of most organisms, especially unicellular microorganisms, are constantly exposed to harsh environmental factors which affect their growth. UV radiation is one of the most important physical parameters which influences yeast growth in nature. Here we used 46 natural strains of Saccharomyces cerevisiae isolated from several natural populations at the "Evolution Canyon" microsite (Nahal Oren, Mt. Carmel, Israel). The opposing slopes of this canyon share the same geology, soil, and macroclimate, but they differ in microclimatic conditions. The interslope differences in solar radiation (200%-800% more on the "African" slope) caused the development of two distinct biomes. The south-facing slope is sunnier and has xeric, savannoid "African" environment while the north-facing slope is represented by temperate, "European" forested environment. Here we studied the phenotypic response of the S. cerevisiae strains to UVA and UVC radiations and to methyl methanesulfonate (MMS) in order to evaluate the interslope effect on the strains' ability to withstand DNA-damaging agents. METHODOLOGY/PRINCIPAL FINDINGS:We exposed our strains to the different DNA-damaging agents and measured survival by counting colony forming units. The strains from the "African" slope were more resilient to both UVA and MMS than the strains from the "European" slope. In contrast, we found that there was almost no difference between strains (with similar ploidy) from the opposite slopes, in their sensitivity to UVC radiation. These results suggest that the "African" strains are more adapted to higher solar radiation than the "European" strains. We also found that the tetraploids strains were more tolerant to all DNA-damaging agents than their neighboring diploid strains, which suggest that high ploidy level might be a mechanism of adaptation to high solar radiation. CONCLUSIONS/SIGNIFICANCE:Our results and the results of parallel studies with several other organisms, suggest that natural selection appears to select, at a microscale, for adaptive complexes that can tolerate the higher UV radiation on the "African" slope
Asymptotically-optimal path planning for manipulation using incremental sampling-based algorithms
A desirable property of path planning for robotic manipulation is the ability to identify solutions in a sufficiently short amount of time to be usable. This is particularly challenging for the manipulation problem due to the need to plan over high-dimensional configuration spaces and to perform computationally expensive collision checking procedures. Consequently, existing planners take steps to achieve desired solution times at the cost of low quality solutions. This paper presents a planning algorithm that overcomes these difficulties by augmenting the asymptotically-optimal RRT* with a sparse sampling procedure. With the addition of a collision checking procedure that leverages memoization, this approach has the benefit that it quickly identifies low-cost feasible trajectories and takes advantage of subsequent computation time to refine the solution towards an optimal one. We evaluate the algorithm through a series of Monte Carlo simulations of seven, twelve, and fourteen degree of freedom manipulation planning problems in a realistic simulation environment. The results indicate that the proposed approach provides significant improvements in the quality of both the initial solution and the final path, while incurring almost no computational overhead compared to the RRT algorithm. We conclude with a demonstration of our algorithm for single-arm and dual-arm planning on Willow Garage's PR2 robot
Characterizing the Habitable Zones of Exoplanetary Systems with a Large Ultraviolet/Visible/Near-IR Space Observatory
Understanding the surface and atmospheric conditions of Earth-size, rocky
planets in the habitable zones (HZs) of low-mass stars is currently one of the
greatest astronomical endeavors. Knowledge of the planetary effective surface
temperature alone is insufficient to accurately interpret biosignature gases
when they are observed in the coming decades. The UV stellar spectrum drives
and regulates the upper atmospheric heating and chemistry on Earth-like
planets, is critical to the definition and interpretation of biosignature
gases, and may even produce false-positives in our search for biologic
activity. This white paper briefly describes the scientific motivation for
panchromatic observations of exoplanetary systems as a whole (star and planet),
argues that a future NASA UV/Vis/near-IR space observatory is well-suited to
carry out this work, and describes technology development goals that can be
achieved in the next decade to support the development of a UV/Vis/near-IR
flagship mission in the 2020s.Comment: Submitted in response to NASA call for white papers: "Large
Astrophysics Missions to Be Studied by NASA Prior to the 2020 Decadal Survey
Near-ultraviolet Excess in Slowly Accreting T Tauri Stars: Limits Imposed by Chromospheric Emission
Young stars surrounded by disks with very low mass accretion rates are likely in the final stages of inner disk evolution and therefore particularly interesting to study. We present ultraviolet (UV) observations of the ~5-9 Myr old stars RECX-1 and RECX-11, obtained with the Cosmic Origins Spectrograph and Space Telescope Imaging Spectrograph on the Hubble Space Telescope , as well as optical and near-infrared spectroscopic observations. The two stars have similar levels of near-UV emission, although spectroscopic evidence indicates that RECX-11 is accreting and RECX-1 is not. The line profiles of H_ and He I _10830 in RECX-11 show both broad and narrow redshifted absorption components that vary with time, revealing the complexity of the accretion flows. We show that accretion indicators commonly used to measure mass accretion rates, e.g., U -band excess luminosity or the Ca II triplet line luminosity, are unreliable for low accretors, at least in the middle K spectral range. Using RECX-1 as a template for the intrinsic level of photospheric and chromospheric emission, we determine an upper limit of 3 _ 10 –10 M _ yr –1 for RECX-11. At this low accretion rate, recent photoevaporation models predict that an inner hole should have developed in the disk. However, the spectral energy distribution of RECX-11 shows fluxes comparable to the median of Taurus in the near-infrared, indicating that substantial dust remains. Fluorescent H 2 emission lines formed in the innermost disk are observed in RECX-11, showing that gas is present in the inner disk, along with the dust.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90770/1/0004-637X_743_2_105.pd
Fluid-structure interaction in abdominal aortic aneurysms: effects of asymmetry and wall thickness
BACKGROUND: Abdominal aortic aneurysm (AAA) is a prevalent disease which is of significant concern because of the morbidity associated with the continuing expansion of the abdominal aorta and its ultimate rupture. The transient interaction between blood flow and the wall contributes to wall stress which, if it exceeds the failure strength of the dilated arterial wall, will lead to aneurysm rupture. Utilizing a computational approach, the biomechanical environment of virtual AAAs can be evaluated to study the affects of asymmetry and wall thickness on this stress, two parameters that contribute to increased risk of aneurysm rupture. METHODS: Ten virtual aneurysm models were created with five different asymmetry parameters ranging from β = 0.2 to 1.0 and either a uniform or variable wall thickness to study the flow and wall dynamics by means of fully coupled fluid-structure interaction (FSI) analyses. The AAA wall was designed to have a (i) uniform 1.5 mm thickness or (ii) variable thickness ranging from 0.5 – 1.5 mm extruded normally from the boundary surface of the lumen. These models were meshed with linear hexahedral elements, imported into a commercial finite element code and analyzed under transient flow conditions. The method proposed was then compared with traditional computational solid stress techniques on the basis of peak wall stress predictions and cost of computational effort. RESULTS: The results provide quantitative predictions of flow patterns and wall mechanics as well as the effects of aneurysm asymmetry and wall thickness heterogeneity on the estimation of peak wall stress. These parameters affect the magnitude and distribution of Von Mises stresses; varying wall thickness increases the maximum Von Mises stress by 4 times its uniform thickness counterpart. A pre-peak systole retrograde flow was observed in the AAA sac for all models, which is due to the elastic energy stored in the compliant arterial wall and the expansion force of the artery during systole. CONCLUSION: Both wall thickness and geometry asymmetry affect the stress exhibited by a virtual AAA. Our results suggest that an asymmetric AAA with regional variations in wall thickness would be exposed to higher mechanical stresses and an increased risk of rupture than a more fusiform AAA with uniform wall thickness. Therefore, it is important to accurately reproduce vessel geometry and wall thickness in computational predictions of AAA biomechanics
Molecular Characterization of a Strawberry FaASR Gene in Relation to Fruit Ripening
BACKGROUND: ABA-, stress- and ripening-induced (ASR) proteins have been reported to act as a downstream component involved in ABA signal transduction. Although much attention has been paid to the roles of ASR in plant development and stress responses, the mechanisms by which ABA regulate fruit ripening at the molecular level are not fully understood. In the present work, a strawberry ASR gene was isolated and characterized (FaASR), and a polyclonal antibody against FaASR protein was prepared. Furthermore, the effects of ABA, applied to two different developmental stages of strawberry, on fruit ripening and the expression of FaASR at transcriptional and translational levels were investigated. METHODOLOGY/PRINCIPAL FINDINGS: FaASR, localized in the cytoplasm and nucleus, contained 193 amino acids and shared common features with other plant ASRs. It also functioned as a transcriptional activator in yeast with trans-activation activity in the N-terminus. During strawberry fruit development, endogenous ABA content, levels of FaASR mRNA and protein increased significantly at the initiation of ripening at a white (W) fruit developmental stage. More importantly, application of exogenous ABA to large green (LG) fruit and W fruit markedly increased endogenous ABA content, accelerated fruit ripening, and greatly enhanced the expression of FaASR transcripts and the accumulation of FaASR protein simultaneously. CONCLUSIONS: These results indicate that FaASR may be involved in strawberry fruit ripening. The observed increase in endogenous ABA content, and enhanced FaASR expression at transcriptional and translational levels in response to ABA treatment might partially contribute to the acceleration of strawberry fruit ripening
Estimating the Ultraviolet Emission of M dwarfs with Exoplanets from Ca II and H
M dwarf stars are excellent candidates around which to search for exoplanets,
including temperate, Earth-sized planets. To evaluate the photochemistry of the
planetary atmosphere, it is essential to characterize the UV spectral energy
distribution of the planet's host star. This wavelength regime is important
because molecules in the planetary atmosphere such as oxygen and ozone have
highly wavelength dependent absorption cross sections that peak in the UV
(900-3200 ). We seek to provide a broadly applicable method of
estimating the UV emission of an M dwarf, without direct UV data, by
identifying a relationship between non-contemporaneous optical and UV
observations. Our work uses the largest sample of M dwarf star far- and near-UV
observations yet assembled. We evaluate three commonly-observed optical
chromospheric activity indices -- H equivalent widths and log
L/L, and the Mount Wilson Ca II H&K S and R indices
-- using optical spectra from the HARPS, UVES, and HIRES archives and new HIRES
spectra. Archival and new Hubble Space Telescope COS and STIS spectra are used
to measure line fluxes for the brightest chromospheric and transition region
emission lines between 1200-2800 . Our results show a correlation
between UV emission line luminosity normalized to the stellar bolometric
luminosity and Ca II R with standard deviations of 0.31-0.61 dex
(factors of 2-4) about the best-fit lines. We also find correlations
between normalized UV line luminosity and H log
L/L and the S index. These relationships allow one to
estimate the average UV emission from M0 to M9 dwarfs when UV data are not
available.Comment: 34 pages, 12 figures, 5 tables (one machine readable table available
online). Accepted to AAS Journal
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