The relevance of point defects in studying silica-based materials from bulk to nanosystems

The macroscopic properties of silica can be modified by the presence of local microscopic modifications at the scale of the basic molecular units (point defects). Such defects can be generated during the production of glass, devices, or by the environments where the latter have to operate, impacting on the devices’ performance. For these reasons, the identification of defects, their generation processes, and the knowledge of their electrical and optical features are relevant for microelectronics and optoelectronics. The aim of this manuscript is to report some examples of how defects can be generated, how they can impact device performance, and how a defect species or a physical phenomenon that is a disadvantage in some fields can be used as an advantage in others

DELAMINAZIONE INTERLAMINARE DI COMPOSITI CFRP AL VARIARE DELLE CONDIZIONI DI CURA DELLA MATRICE

In questo lavoro si è condotto uno studio sperimentale del comportamento a delaminazione interlaminare in Modo I di laminati compositi unidirezionali in fibra di carbonio e matrice epossidica (CFRP), al variare delle condizioni di cura della matrice. Tutti i sistemi analizzati hanno utilizzato lo stesso tessuto e lo stesso monomero epossidico DGEBA. Variando il processo di cura (cura termica o mediante radiazioni), gli agenti di cura (ammine o anidridi per i sistemi curati termicamente), e l’impiego di additivi tenacizzanti (es. il PES per i sistemi irradiati), è stato possibile controllare e modificare sia il grado di adesione fibra/matrice, che il grado di fragilità della matrice (monitorato attraverso il Fattore Critico di Intensificazione degli Sforzi KIC). Il lavoro quindi propone una analisi critica dei meccanismi di resistenza alla delaminazione controllati dalla tenacità della matrice e dalla resistenza dell’interfaccia fibra-matrice, mediante la determinazione delle Curve di Resistenza e dei valori di GIC di Innesco e di Propagazione ottenuti per i diversi sistemi presi in esame

The durability of carbon fiber/epoxy composites under hydrothermal ageing

Studies on fibre reinforced composites are now receiving greater attention. Industrial applications have been successful in areas like aerospace, automobile, marine, construction and sporting goods. The first generation of epoxy resins for use in carbon fibre composites are able to achieve optimized high stiffness modules and high heat resistance by a high crosslink density, reached through thermal curing. However, these formulations can be very toxic and brittle with low crack resistance, which was a major disadvantage for structural applications. In the last years the use of ionizing radiation as alternative to thermal curing has been proposed as an environmentally friendly process. Furthermore, in order to enhance toughness mechanical requirements for their applications, the formulation generally consists of blends of epoxy resins and engineering thermoplastics. In terms of durability (service life and reliability), in these materials it depends on different environmental conditions (temperature, moisture, etc.), and it is very important to know how their properties are modified after the exposure to different temperature and moisture absorption cycles. In this work carbon fibre composites produced by ionizing radiation induced curing of the epoxy based matrices have been subjected to thermal and moisture absorption ageing and the influence of these treatments on the thermal and mechanical properties has been investigated through dynamic mechanical thermal analysis and mechanical fracture toughness tests

Role of the Recoil Ion in Single-Electron Capture and Single-Ionization Processes for Collisions of Protons with He and Ar Atoms

In this work the single-electron capture and single-ionization processes are studied for proton collisions with He and Ar atoms at impact energies in the range 25–100 keV. Classical trajectory Monte Carlo simulations are benchmarked against experimental data obtained at the reaction microscope in Bariloche, Argentina, which employs the cold target recoil-ion momentum spectroscopy technique. Special emphasis is placed on describing the momentum transfer to the recoil ion for these collision systems

Studies of network organization and dynamics of e-beam crosslinked PVPs: From macro to nano

In this work the influence of poly(N-vinylpyrrolidone)(PVP)concentration in water on the organization and dynamics of the corresponding macro-/nanogel networks has been systematically investigated. Irradiation has been performed at the same irradiation dose(within the sterilization dose range)and dose rate. In the selected irradiation conditions, the transition between macroscopic gelation and micro/nanogels formation is observed just below the critical overlap concentration(1 wt%),whereas the net prevalence of intramolecular over intermolecular crosslinking occurs at a lower polymer concentration(below 0.25 wt%). Dynamic\u2013mechanical spectroscopy has been applied as a classical methodology to estimate the network mesh size for macrogels in their swollen state, while 13C NMR spin\u2013lattice relaxation spectroscopy has been applied on both the macrogel and nanogel freeze dried residues to withdraw interesting information of the network spatial organization in the passage of scale from macrotonano

RADIATION CROSSLINKED HYDROGELS WITH EGG WHITE PROTEINS FOR WOUND HEALING

The wound healing process is a complex and dynamic interaction among cytokines, growth factors, blood, and the extracellular matrix. [1] Due to the influence of potential physiological conditions, such as diabetes, any disorder of these factors will lead to chronic wound healing. In chronic wounds, an excessive inflammatory response prevents the proliferation of the healthy tissue, causing a serious infection which can also result in an amputation. If not treated properly, chronic wound might even be life-threatening. [2] Egg white proteins, such as ovoalbumin, ovotransferrin and lysozyme, are attracting interest especially because of their demonstrated antioxidant and antibacterial activities. [3] These bioactive proteins can then be used to enrich advanced wound dressing films that can help control wound oxidative stress and thereby accelerate wound healing and/or prevent bacterial infection. Wound dressing films can be easily produced crosslinking polymers, such as polyvinyl alcohol (PVA) or polyvinyl pyrrolidone (PVP), by high-energy radiation. [4] This technique does not require expensive initiators and catalysts and it can guarantee simultaneous product sterilization, depending on the irradiation doses. PVA hydrogels obtained by irradiation are also transparent, a desirable property for wound dressings. When PVA is mixed with selected polysaccharides, the hydrogel wound dressings have shown faster healing rates and scarless healing, probably due to antioxidant properties of polysaccharide fragments produced upon irradiation. [4] The aim of this work is to develop novel hydrogel formulations, based on blends of synthetic polymers and polysaccharides, and incorporating egg white proteins and/or their peptides, to investigate their applicability as advanced wound dressings

Design and performance of a Martian autonomous navigation system based on a smallsat constellation

Deciphering the genesis and evolution of the Martian polar caps can provide crucial understanding of Mars' climate system and will be a big step forward for comparative climatology of the terrestrial planets. The growing scientific interest for the exploration of Mars at high latitudes, together with the need of minimizing the resources onboard landers and rovers, motivates the need for an adequate navigation support from orbit. In the context of the ARES4SC study, we propose a novel concept based on a constellation that can support autonomous navigation of different kind of users devoted to scientific investigations of those regions. We study two constellations, that differ mainly for the semi-major axis and the inclination of the orbits, composed of 5 small satellites (based on the SmallSats design being developed in Argotec), offering dedicated coverage of the Mars polar regions. We focus on the architecture of the inter-satellite links (ISL), the key elements providing both ephemerides and time synchronization for the broadcasting of the navigation message. Our concept is based on suitably configured coherent links, able to suppress the adverse effects of on-board clock instabilities and to provide excellent range-rate accuracies between the constellation's nodes. The data quality allows attaining good positioning performance for both constellations with a largely autonomous system. Indeed, we show that ground support can be heavily reduced by employing an ISL communication architecture. Periodic synchronization of the clocks on-board the constellation nodes with terrestrial time (TT) is enabled through the main spacecraft (the mother-craft), the only element of the constellation enabling radio communication with the Earth. We report on the results of numerical simulations in different operational scenarios and show that a very high-quality orbit reconstruction can be obtained for the constellation nodes using a batch-sequential filter or a batch filter with overlapping arcs, that could be implemented on board the mother-craft, thus enabling a high level of navigation autonomy. The assessment of the achievable positioning accuracy with this concept is fundamental to evaluate the feasibility of a future positioning system providing a global coverage of the red planet

Role of Interleukin 17 in arthritis chronicity through survival of synoviocytes via regulation of synoviolin expression

Background: The use of TNF inhibitors has been a major progress in the treatment of chronic inflammation. However, not all patients respond. In addition, response will be often lost when treatment is stopped. These clinical aspects indicate that other cytokines might be involved and we focus here on the role of IL-17. In addition, the chronic nature of joint inflammation may contribute to reduced response and enhanced chronicity. Therefore we studied the capacity of IL-17 to regulate synoviolin, an E3 ubiquitin ligase implicated in synovial hyperplasia in human rheumatoid arthritis (RA) FLS and in chronic reactivated streptococcal cell wall (SCW)-induced arthritis.<p></p> Methodology/Principal Findings: Chronic reactivated SCW-induced arthritis was examined in IL-17R deficient and wild-type mice. Synoviolin expression was analysed by real-time RT-PCR, Western Blot or immunostaining in RA FLS and tissue, and p53 assessed by Western Blot. Apoptosis was detected by annexin V/propidium iodide staining, SS DNA apoptosis ELISA kit or TUNEL staining and proliferation by PCNA staining. IL-17 receptor A (IL-17RA), IL-17 receptor C (IL-17-RC) or synoviolin inhibition were achieved by small interfering RNA (siRNA) or neutralizing antibodies. IL-17 induced sustained synoviolin expression in RA FLS. Sodium nitroprusside (SNP)-induced RA FLS apoptosis was associated with reduced synoviolin expression and was rescued by IL-17 treatment with a corresponding increase in synoviolin expression. IL-17RC or IL-17RA RNA interference increased SNP-induced apoptosis, and decreased IL-17-induced synoviolin. IL-17 rescued RA FLS from apoptosis induced by synoviolin knockdown. IL-17 and TNF had additive effects on synoviolin expression and protection against apoptosis induced by synoviolin knowndown. In IL-17R deficient mice, a decrease in arthritis severity was characterized by increased synovial apoptosis, reduced proliferation and a marked reduction in synoviolin expression. A distinct absence of synoviolin expressing germinal centres in IL-17R deficient mice contrasted with synoviolin positive B cells and Th17 cells in synovial germinal centre-like structures.<p></p> Conclusion/Significance: IL-17 induction of synoviolin may contribute at least in part to RA chronicity by prolonging the survival of RA FLS and immune cells in germinal centre reactions. These results extend the role of IL-17 to synovial hyperplasia.<p></p&gt

New catalogue of optically visible open clusters and candidates

We have compiled a new catalogue of open clusters in the Galaxy which updates the previous catalogues of Lynga (1987) and of Mermilliod (1995) (included in the WEBDA database). New objects and new data, in particular, data on kinematics (proper motions) that were not present in the old catalogues, have been included. Virtually all the clusters (1537) presently known were included, which represents an increment of about 347 objects relative to the Lynga (1987) catalogue. The catalogue is presented in a single table containing all the important data, which makes it easy to use. The catalogue can be accessed on line either at http://www.iagusp.usp.br/~wilton/ or as an electronic table which will be made available at the CDS.Comment: 3 pages, submitted to A&

A Motivating Exploration on Lunar Craters and Low-Energy Dynamics in the Earth -- Moon System

It is known that most of the craters on the surface of the Moon were created by the collision of minor bodies of the Solar System. Main Belt Asteroids, which can approach the terrestrial planets as a consequence of different types of resonance, are actually the main responsible for this phenomenon. Our aim is to investigate the impact distributions on the lunar surface that low-energy dynamics can provide. As a first approximation, we exploit the hyberbolic invariant manifolds associated with the central invariant manifold around the equilibrium point L_2 of the Earth - Moon system within the framework of the Circular Restricted Three - Body Problem. Taking transit trajectories at several energy levels, we look for orbits intersecting the surface of the Moon and we attempt to define a relationship between longitude and latitude of arrival and lunar craters density. Then, we add the gravitational effect of the Sun by considering the Bicircular Restricted Four - Body Problem. As further exploration, we assume an uniform density of impact on the lunar surface, looking for the regions in the Earth - Moon neighbourhood these colliding trajectories have to come from. It turns out that low-energy ejecta originated from high-energy impacts are also responsible of the phenomenon we are considering.Comment: The paper is being published in Celestial Mechanics and Dynamical Astronomy, vol. 107 (2010