26th Annual Computational Neuroscience Meeting (CNS*2017): Part 3 - Meeting Abstracts - Antwerp, Belgium. 15–20 July 2017

This work was produced as part of the activities of FAPESP Research,\ud Disseminations and Innovation Center for Neuromathematics (grant\ud 2013/07699-0, S. Paulo Research Foundation). NLK is supported by a\ud FAPESP postdoctoral fellowship (grant 2016/03855-5). ACR is partially\ud supported by a CNPq fellowship (grant 306251/2014-0)

Toward Atmospheric Correction Algorithms for Sentinel-3/OLCI Images of Productive Waters

Atmospheric correction of remote sensing imagery over optically complex waters is still a challenging task. Even algorithms showing a good accuracy for moderate and extremely turbid waters need to be tested when being used for eutrophic inland basins. Such a test was carried out in this study on the example of a Sentinel-3/OLCI image of the productive waters of the Gorky Reservoir during the period of intense blue-green algal bloom using data on the concentration of chlorophyll a and remote sensing reflectance measured from the motorboat at many points of the reservoir. The accuracy of four common atmospheric correction (AC) algorithms was examined. All of them showed unsatisfactory accuracy due to incorrect determination of atmospheric aerosol parameters and aerosol radiance. The calculated aerosol optical depth (AOD) spectra varied widely (AOD(865) = 0.005 − 0.692) even over a small area (up to 10 × 10 km) and correlated with the measured chlorophyll a. As a result, a part of the high water-leaving signal caused by phytoplankton bloom was taken as an atmosphere signal. A significant overestimation of atmospheric aerosol parameters, as a consequence, led to a strong underestimation of the remote sensing reflectance and low accuracy of the considered AC algorithms. To solve this problem, an algorithm with a fixed AOD was proposed. The fixed AOD spectrum was determined in the area with relatively “clean” water as 5 percentiles of AOD in all water pixels. The proposed algorithm made it possible to obtain the remote sensing reflectance with high accuracy. The slopes of linear regression are close to 1 and the intercepts tend to zero in almost all spectral bands. The determination coefficients are more than 0.9; the bias, mean absolute percentage error, and root-mean-square error are notably lower than for other AC algorithms

Toward Atmospheric Correction Algorithms for Sentinel-3/OLCI Images of Productive Waters

Atmospheric correction of remote sensing imagery over optically complex waters is still a challenging task. Even algorithms showing a good accuracy for moderate and extremely turbid waters need to be tested when being used for eutrophic inland basins. Such a test was carried out in this study on the example of a Sentinel-3/OLCI image of the productive waters of the Gorky Reservoir during the period of intense blue-green algal bloom using data on the concentration of chlorophyll a and remote sensing reflectance measured from the motorboat at many points of the reservoir. The accuracy of four common atmospheric correction (AC) algorithms was examined. All of them showed unsatisfactory accuracy due to incorrect determination of atmospheric aerosol parameters and aerosol radiance. The calculated aerosol optical depth (AOD) spectra varied widely (AOD(865) = 0.005 − 0.692) even over a small area (up to 10 × 10 km) and correlated with the measured chlorophyll a. As a result, a part of the high water-leaving signal caused by phytoplankton bloom was taken as an atmosphere signal. A significant overestimation of atmospheric aerosol parameters, as a consequence, led to a strong underestimation of the remote sensing reflectance and low accuracy of the considered AC algorithms. To solve this problem, an algorithm with a fixed AOD was proposed. The fixed AOD spectrum was determined in the area with relatively “clean” water as 5 percentiles of AOD in all water pixels. The proposed algorithm made it possible to obtain the remote sensing reflectance with high accuracy. The slopes of linear regression are close to 1 and the intercepts tend to zero in almost all spectral bands. The determination coefficients are more than 0.9; the bias, mean absolute percentage error, and root-mean-square error are notably lower than for other AC algorithms

Aerosol Optical Properties above Productive Waters of Gorky Reservoir for Atmospheric Correction of Sentinel-3/OLCI Images

The main challenge that one has to face during the atmospheric correction (AC) of productive inland waters is the inability to correctly separate aerosol radiance from water-leaving radiance in the near-infrared range (NIR) bands. This leads both to incorrect estimates of the aerosol parameters and the remote-sensing reflectance (Rrs). For the Gorky Reservoir, where we are developing regional bio-optical models, the situation is complicated by the lack of field measurements of aerosol optical properties due to the significant remoteness of AERONET stations. The standard AC algorithms, as shown earlier, greatly overestimated the aerosol radiance in all spectral bands up to red bands during the period of intense cyanobacteria blooms, while the algorithm with a fixed aerosol optical depth (AOD) obtained in a clean water area gave encouraging results. Therefore, it was important to investigate the characteristics of the atmosphere above the reservoir and validate the proposed approach for regular use of Sentinel-3 imagery of the Gorky Reservoir. To solve these issues, regular in situ aerosol measurements using the handheld sun photometer SPM were performed. The measured AOD and the Angstrom exponent were compared with the estimates of these parameters from two Sentinel-3/OLCI Level-2 products, namely, Synergy (SYN) and Water Full Resolution products (OL_2_WFR). It was found that AOD and the Angstrom exponent from these standard products were overestimated by 2–3 times and almost 2 times in all cases. Atmospheric correction with fixed AOD, defined by measurements, allows us to completely get rid of negative Rrs, and its shapes and values became typical for the Gorky Reservoir. Despite the overestimation of AOD in traditional AC and its large variations in general, it was found that the minimum AOD spectrum is close to the measured spectrum. Therefore, the AOD spectra, which correspond to the two percentiles of the distribution, can be used for preliminary AC with a fixed AOD of the Sentinel-3/OLCI imaginary. The relative errors of the Rrs retrievals using the two percentile AOD compared to the measured AOD were 3–35% in the green and red bands of Sentinel-3/OLCI

Prospective observational cohort study on grading the severity of postoperative complications in global surgery research

Background The Clavien–Dindo classification is perhaps the most widely used approach for reporting postoperative complications in clinical trials. This system classifies complication severity by the treatment provided. However, it is unclear whether the Clavien–Dindo system can be used internationally in studies across differing healthcare systems in high- (HICs) and low- and middle-income countries (LMICs). Methods This was a secondary analysis of the International Surgical Outcomes Study (ISOS), a prospective observational cohort study of elective surgery in adults. Data collection occurred over a 7-day period. Severity of complications was graded using Clavien–Dindo and the simpler ISOS grading (mild, moderate or severe, based on guided investigator judgement). Severity grading was compared using the intraclass correlation coefficient (ICC). Data are presented as frequencies and ICC values (with 95 per cent c.i.). The analysis was stratified by income status of the country, comparing HICs with LMICs. Results A total of 44 814 patients were recruited from 474 hospitals in 27 countries (19 HICs and 8 LMICs). Some 7508 patients (16·8 per cent) experienced at least one postoperative complication, equivalent to 11 664 complications in total. Using the ISOS classification, 5504 of 11 664 complications (47·2 per cent) were graded as mild, 4244 (36·4 per cent) as moderate and 1916 (16·4 per cent) as severe. Using Clavien–Dindo, 6781 of 11 664 complications (58·1 per cent) were graded as I or II, 1740 (14·9 per cent) as III, 2408 (20·6 per cent) as IV and 735 (6·3 per cent) as V. Agreement between classification systems was poor overall (ICC 0·41, 95 per cent c.i. 0·20 to 0·55), and in LMICs (ICC 0·23, 0·05 to 0·38) and HICs (ICC 0·46, 0·25 to 0·59). Conclusion Caution is recommended when using a treatment approach to grade complications in global surgery studies, as this may introduce bias unintentionally

The surgical safety checklist and patient outcomes after surgery: a prospective observational cohort study, systematic review and meta-analysis

© 2017 British Journal of Anaesthesia Background: The surgical safety checklist is widely used to improve the quality of perioperative care. However, clinicians continue to debate the clinical effectiveness of this tool. Methods: Prospective analysis of data from the International Surgical Outcomes Study (ISOS), an international observational study of elective in-patient surgery, accompanied by a systematic review and meta-analysis of published literature. The exposure was surgical safety checklist use. The primary outcome was in-hospital mortality and the secondary outcome was postoperative complications. In the ISOS cohort, a multivariable multi-level generalized linear model was used to test associations. To further contextualise these findings, we included the results from the ISOS cohort in a meta-analysis. Results are reported as odds ratios (OR) with 95% confidence intervals. Results: We included 44 814 patients from 497 hospitals in 27 countries in the ISOS analysis. There were 40 245 (89.8%) patients exposed to the checklist, whilst 7508 (16.8%) sustained ≥1 postoperative complications and 207 (0.5%) died before hospital discharge. Checklist exposure was associated with reduced mortality [odds ratio (OR) 0.49 (0.32–0.77); P\u3c0.01], but no difference in complication rates [OR 1.02 (0.88–1.19); P=0.75]. In a systematic review, we screened 3732 records and identified 11 eligible studies of 453 292 patients including the ISOS cohort. Checklist exposure was associated with both reduced postoperative mortality [OR 0.75 (0.62–0.92); P\u3c0.01; I2=87%] and reduced complication rates [OR 0.73 (0.61–0.88); P\u3c0.01; I2=89%). Conclusions: Patients exposed to a surgical safety checklist experience better postoperative outcomes, but this could simply reflect wider quality of care in hospitals where checklist use is routine

Critical care admission following elective surgery was not associated with survival benefit: prospective analysis of data from 27 countries

This was an investigator initiated study funded by Nestle Health Sciences through an unrestricted research grant, and by a National Institute for Health Research (UK) Professorship held by RP. The study was sponsored by Queen Mary University of London