The Fall of Teotihuacan

In this project I present a survey of multiple theories regarding the dissolution of the ancient Mesoamerican city of Teotihuacan. This complex city-state was established around 100 BCE and became one of the largest and most powerful sites in Mesoamerica. Located about 25 miles northeast of what is today known as Mexico City, Teotihuacan was home to many advanced technological and social structures, including a pyramid called The Pyramid of the Sun that boasted a base as large as the Great Pyramid of Giza’s. At some time between the 7th and 8th century CE, Teotihuacan went into decline. On this poster, I highlight a few of the most prominent theories regarding the cause of this decline and then conclude with my own observations.https://scholarscompass.vcu.edu/uresposters/1119/thumbnail.jp

Evaluation of Yield of Wells in Ado-Ekiti, Nigeria

Pumping tests were conducted on twenty selected boreholes and five hand-dug wells cut across Ado Ekiti Metropolitan (AEM) area, with the view to ascertain yield of the wells. Constant rate pumping test and recovery method test were carried out. It was revealled that discharge is directly proportional to the yield of the boreholes and hand-dug wells at a constant drawdown, hence the discharge rate  gives the yield of each of the selected boreholes. The borehole depth ranges between 40 – 120 m while hand-dug well ranges between 3 – 15m. Borehole yield in the AEM area ranged between 0.267 l/s and 2.0 l/s. The yield was not totally dependent on the depths, but also on such parameters as porosity and permeability.  The potential of groundwater in AEM as it relates to quantity is high as all wells yielded water. The average water consumption in litres per person per day for high class income earners was estimated at 196 l/d, while that of low class income earners was 119 l/d. Most residence in AEM depend on ground water for domestic water demand. Possible improvement strategies to groundwater exploitation were highlighted. These improvement strategies and remedies are predrilling geophysical survey before siting of boreholes, monitoring groundwater exploration to avert depletion of groundwater potential zones encouraging sufficient recharge period and conducting regular laboratory tests. Keywords: yield, boreholes, hand-dug wells, recharge, Ado Ekiti

Comparison between unipolar and bipolar single phase grid-connected inverters for PV applications

An inverter is essential for the interfacing of photovoltaic panels with the AC network. There are many possible inverter topologies and inverter switching schemes and each one will have its own relative advantages and disadvantages. Efficiency and output current distortion are two important factors governing the choice of inverter system. In this paper, it is argued that current controlled inverters offer significant advantages from the point of view of minimisation of current distortion. Two inverter switching strategies are explored in detail. These are the unipolar current controlled inverter and the bipolar current controlled inverter. With respect to low frequency distortion, previously published works provide theoretical arguments in favour of bipolar switching. On the other hand it has also been argued that the unipolar switched inverter offers reduced switching losses and generates less EMI. On efficiency grounds, it appears that the unipolar switched inverter has an advantage. However, experimental results presented in this paper show that the level of low frequency current distortion in the unipolar switched inverter is such that it can only comply with Australian Standard 4777.2 above a minimum output current. On the other hand it is shown that at the same current levels bipolar switching results in reduced low frequency harmonics

Occurrence and assemblage composition of intertidal non-native species may be influenced by shipping patterns and artificial structures

Habitat modification coupled with the spread of non-native species (NNS) are among the top threats to marine biodiversity globally. Species are known to be transported to new locations via international shipping and secondarily spread via regional vessels and artificial structures. Rapid Assessment Surveys (RAS) combining quantitative and semi-quantitative methods compared NNS richness and assemblage composition on intertidal natural rocky shores and artificial structures in harbours in different regions along the south coast of England. Quantitative data showed that artificial habitats supported higher richness than natural habitats, while semi-quantitative data found no difference in richness among habitat types. This result was attributed to additional species found in rock pools during searches of complex microhabitats in natural habitats. Assemblages on artificial structures differed among regions, with regions and harbours with greater numbers of vessels supporting greater richness. Results highlight the importance of shipping and artificial structures for NNS introduction and spread

Multivariate moment closure techniques for stochastic kinetic models.

Stochastic effects dominate many chemical and biochemical processes. Their analysis, however, can be computationally prohibitively expensive and a range of approximation schemes have been proposed to lighten the computational burden. These, notably the increasingly popular linear noise approximation and the more general moment expansion methods, perform well for many dynamical regimes, especially linear systems. At higher levels of nonlinearity, it comes to an interplay between the nonlinearities and the stochastic dynamics, which is much harder to capture correctly by such approximations to the true stochastic processes. Moment-closure approaches promise to address this problem by capturing higher-order terms of the temporally evolving probability distribution. Here, we develop a set of multivariate moment-closures that allows us to describe the stochastic dynamics of nonlinear systems. Multivariate closure captures the way that correlations between different molecular species, induced by the reaction dynamics, interact with stochastic effects. We use multivariate Gaussian, gamma, and lognormal closure and illustrate their use in the context of two models that have proved challenging to the previous attempts at approximating stochastic dynamics: oscillations in p53 and Hes1. In addition, we consider a larger system, Erk-mediated mitogen-activated protein kinases signalling, where conventional stochastic simulation approaches incur unacceptably high computational costs

Early time course of major bleeding on antiplatelet therapy after TIA or ischemic stroke

Objective: To study the early time course of major bleeding and its subtypes in patients with cerebral ischemia on dual and single antiplatelet therapy. Methods: We performed a post hoc analysis on individual patient data from 6 randomized clinical trials (Clopidogrel Versus Aspirin in Patients at Risk of Ischaemic Events [CAPRIE], Second European Stroke Prevention Study [ESPS-2], Management of Atherothrombosis With Clopidogrel in High Risk Patients [MATCH], Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management, and Avoidance [CHARISMA], European/Australasian Stroke Prevention in Reversible Ischaemia Trial [ESPRIT], and Prevention Regimen for Effectively Avoiding Second Strokes [PRoFESS]) including 45,195 patients with a TIA or noncardioembolic ischemic stroke. We studied incidence rates of bleeding per antiplatelet regimen stratified by time from randomization (≤30, 31–90, 91–180, 181–365, >365 days). We calculated incidence rates per trial and pooled estimates with random-effects meta-analysis. We performed Poisson regression to assess differences between time periods with adjustment for age and sex. Results: The incidence of major bleeding on aspirin plus clopidogrel and aspirin plus -dipyridamole was highest in the first 30 days, 5.8 and 4.9 per 100 person-years, respectively, and was significantly higher than at 31 to 90 days (rate ratio 1.98, 95% confidence interval 1.16–3.40 for aspirin plus clopidogrel; rate ratio 1.94, 95% confidence interval 1.24–3.03 for aspirin plus dipyridamole). Incidence rates on aspirin and clopidogrel monotherapy were 2.8 and 2.5 per 100 person-years, respectively, in the first 30 days, with no significant change over time. The time course was similar for gastrointestinal bleeds. There was no early excess of intracranial hemorrhage in patients on either dual or single antiplatelet therapy. Conclusion: Dual antiplatelet therapy is associated with high early risks of major and gastrointestinal bleeding that decline after the first month in trial cohorts

Postcolonial town planning in Commonwealth nations: A case study of the Solomon Islands - an agenda for change

This is the author's PDF version of an article published in The Round Table: The Commonwealth Journal of International Affairs© 2007. The definitive version is available at www.informaworld.comThe principal argument advanced in this paper is that spatial planning in the Solomon Islands has failed to deliver any substantive benefits and is therefore in urgent need of reform. The present model of planning, derived from a combination of colonial practice and legislation originating in the UK, does not add much, if any, value to the development process. The poor quality of planning in the Solomons cannot be seen in isolation. There are similar systems in use throughout much of the Commonwealth and anecdotal evidence suggests that the failings are widely duplicated. The Solomon Islands only appear exceptional in the extent to which other government systems have demonstrably broken down, following the 'Ethnic Tension' of 2000 - 03. The Regional Assistance Mission to the Solomon Islands (RAMSI) provides a unique opportunity for a review of the way in which planning operates. A number of issues are identified which any reformed system must address

Hate speech and hate crimes: a data-driven study of evolving discourse around marginalized groups

This study explores the dynamic relationship between online discourse, as observed in tweets, and physical hate crimes, focusing on marginalized groups. Leveraging natural language processing techniques, including keyword extraction and topic modeling, we analyze the evolution of online discourse after events affecting these groups. Examining sentiment and polarizing tweets, we establish correlations with hate crimes in Black and LGBTQ+ communities. Using a knowledge graph, we connect tweets, users, topics, and hate crimes, enabling network analyses. Our findings reveal divergent patterns in the evolution of user communities for Black and LGBTQ+ groups, with notable differences in sentiment among influential users. This analysis sheds light on distinctive online discourse patterns and emphasizes the need to monitor hate speech to prevent hate crimes, especially following significant events impacting marginalized communities

Extent of hypoattenuation on CT angiography source images in Basilar Artery occlusion: prognostic value in the Basilar Artery International Cooperation Study

<p><b>Background and Purpose:</b> The posterior circulation Acute Stroke Prognosis Early CT Score (pc-ASPECTS) quantifies the extent of early ischemic changes in the posterior circulation with a 10-point grading system. We hypothesized that pc-ASPECTS applied to CT angiography source images predicts functional outcome of patients in the Basilar Artery International Cooperation Study (BASICS).</p> <p><b>Methods:</b> BASICS was a prospective, observational registry of consecutive patients with acute symptomatic basilar artery occlusion. Functional outcome was assessed at 1 month. We applied pc-ASPECTS to CT angiography source images of patients with CT angiography for confirmation of basilar artery occlusion. We calculated unadjusted and adjusted risk ratios (RRs) of pc-ASPECTS dichotomized at ≥8 versus <8. Primary outcome measure was favorable outcome (modified Rankin Scale scores 0–3). Secondary outcome measures were mortality and functional independence (modified Rankin Scale scores 0–2).</p> <p><b>Results:</b> Of 158 patients included, 78 patients had a CT angiography source images pc-ASPECTS ≥8. Patients with a pc-ASPECTS ≥8 more often had a favorable outcome than patients with a pc-ASPECTS <8 (crude RR, 1.7; 95% CI, 0.98–3.0). After adjustment for age, baseline National Institutes of Health Stroke Scale score, and thrombolysis, pc-ASPECTS ≥8 was not related to favorable outcome (RR, 1.3; 95% CI, 0.8–2.2), but it was related to reduced mortality (RR, 0.7; 95% CI, 0.5–0.98) and functional independence (RR, 2.0; 95% CI, 1.1–3.8). In post hoc analysis, pc-ASPECTS dichotomized at ≥6 versus <6 predicted a favorable outcome (adjusted RR, 3.1; 95% CI, 1.2–7.5).</p> <p><b>Conclusions:</b> pc-ASPECTS on CT angiography source images independently predicted death and functional independence at 1 month in the CT angiography subgroup of patients in the BASICS registry.</p&gt