24 research outputs found
Note prĂ©liminaire sur lâhabitat de Quinquiris (Castelnaudary, Aude) Ă la fin du premier Ăąge du Fer
La troisiĂšme tranche du projet du PRAE Nicolas Appert au sud de Castelnaudary (Aude) a donnĂ© lieu Ă une fouille prĂ©ventive au printemps 2012. Le site de Quinquiris a livrĂ© des vestiges nĂ©olithiques, protohistoriques et gallo-romains. Seule lâoccupation de la fin du premier Ăąge du Fer est ici prĂ©sentĂ©e. Elle correspond Ă un ensemble structurĂ© de plans de bĂątiments sur poteaux et parois en torchis, de silos et fosses de rejet attribuables au Ve s. av. J.âC., concentrĂ© au nord de lâemprise de fouille.South of Castelnaudary (Aude), the third phase of the project of the PRAE Nicolas Appert has led to archaeological survey excavations in spring 2012. The neolithic, protohistoric and Gallo-Roman periods are represented on the site of Quinquiris. Only the end of the First Iron Age (5th century BC) is related in this article. It is characterized by a settlement with postholes and claywall defining several buildings, silos and some refuse pits, concentrated in the north of the excavations
Note prĂ©liminaire sur lâhabitat de Quinquiris (Castelnaudary, Aude) Ă la fin du premier Ăąge du Fer
La troisiĂšme tranche du projet du PRAE Nicolas Appert au sud de Castelnaudary (Aude) a donnĂ© lieu Ă une fouille prĂ©ventive au printemps 2012. Le site de Quinquiris a livrĂ© des vestiges nĂ©olithiques, protohistoriques et gallo-romains. Seule lâoccupation de la fin du premier Ăąge du Fer est ici prĂ©sentĂ©e. Elle correspond Ă un ensemble structurĂ© de plans de bĂątiments sur poteaux et parois en torchis, de silos et fosses de rejet attribuables au Ve s. av. J.âC., concentrĂ© au nord de lâemprise de fouille.South of Castelnaudary (Aude), the third phase of the project of the PRAE Nicolas Appert has led to archaeological survey excavations in spring 2012. The neolithic, protohistoric and Gallo-Roman periods are represented on the site of Quinquiris. Only the end of the First Iron Age (5th century BC) is related in this article. It is characterized by a settlement with postholes and claywall defining several buildings, silos and some refuse pits, concentrated in the north of the excavations
Toulouse Saint-Roch : village dâartisans et dâĂ©changes. Premiers rĂ©sultats de la fouille 2009-2011 sur la ZAC Niel (Haute-Garonne)
National audienc
Une maison Ă cour centrale sur le site de Saint-Roch (ZAC Niel) Ă Toulouse (Haute-Garonne)
International audienc
Une maison Ă cour centrale sur le site de Saint-Roch (ZAC Niel) Ă Toulouse (Haute-Garonne)
International audienc
La sépulture de Pessac (Gironde) : un lot de céramique singulier au sein du campaniforme atlantique et européen
International audienc
New data on Late NeolithicâEarly Bronze Age occupation in the Bordeaux MeÌtropole area
Nouvelles donnĂ©es sur lâoccupation du sol du NĂ©olithique final Ă lâĂąge du Bronze ancien sur le territoire de Bordeaux MĂ©tropole.
Depuis la crĂ©ation en 2013 du Centre archĂ©ologie prĂ©ventive de Bordeaux MĂ©tropole, de nombreuses fouilles ont Ă©tĂ© rĂ©alisĂ©es dans lâintercommunalitĂ©. Plusieurs de ces opĂ©rations ont permis lâidentification dâindices archĂ©ologiques se rapportant au NĂ©olithique final et Ă lâĂąge du Bronze ancien. Cet article prĂ©sente un bref compte-rendu des rĂ©sultats obtenus sur les trois principaux points de dĂ©couverte de tels vestiges : le secteur Jean PrĂ©vĂŽt Ă Bassens, la Place RoumĂ©goux Ă Gradignan et lâavenue Roger Chaumet Ă Pessac. Ces dĂ©couvertes constituent de nouveaux points de rĂ©fĂ©rence venant enrichir nos connaissances sur des pĂ©riodes qui demeurent mal cernĂ©es Ă lâĂ©chelle rĂ©gionale.Alcantara AurĂ©lien, BĂ©hague Bertrand, Dumas Antoine. Nouvelles donnĂ©es sur lâoccupation du sol du NĂ©olithique final Ă lâĂąge du Bronze ancien sur le territoire de Bordeaux MĂ©tropole.. In: Aquitania : une revue inter-rĂ©gionale d'archĂ©ologie, tome 36, 2020. pp. 13-24
CAR-T cells and BiTEs in solid tumors: challenges and perspectives
International audienceChimeric antigen receptor (CAR)-modified T cells and BiTEs are both immunotherapies which redirect T cell specificity against a tumor-specific antigen through the use of antibody fragments. They demonstrated remarkable efficacy in B cell hematologic malignancies, thus paving the way for their development in solid tumors. Nonetheless, the use of such new drugs to treat solid tumors is not straightforward. So far, the results from early phase clinical trials are not as impressive as expected but many improvements are under way. In this review we present an overview of the clinical development of CAR-T cells and BiTEs targeting the main antigens expressed by solid tumors. We emphasize the most frequent hurdles encountered by either CAR-T cells or BiTEs, or both, and summarize the strategies that have been proposed to overcome these obstacles
Eysses avant <i>Excisum</i> : une agglomération gauloise prÚs de Villeneuve-sur-Lot (Lot-et-Garonne)
International audienceEysses, located in Villeneuve-sur-Lot, at the North of Agen, was, until recently, mainly known for its vicus: Excisum, mentioned in the itinerary of Antoninus and the Table of Peutinger. For about ten years now, many investigations have been conducted by the Inrap, the Archaeology and History Society of Villeneuve-sur-Lot and the Regional Service of Archaeology of Aquitaine. They have revealed a dense and extended occupation of the final Tene at the east of the roman monumental center. Thus, the six preventive excavations made by the Inrap between 2005 and 2009 have enabled to study larger areas and to identify more precisely the different aspects of the occupation of the 2nd century BC. Therefore, some domestic and artisanal areas have been identified. They are particularly characterized by the presence of buildings, wells and pottery kilns. Moreover, the important amount of italic imports reveals there were some important contacts with the Mediterranean world