Brexit is finally going ahead. Is it the wrong answer to the right question?

In this blog for the LSE, I examine the socio-political causes of the Brexit vote

Innovation and the Evidence Base

Innovation has been a persistent theme in probation reform and probation practice over recent years. At a system level, when the Coalition government’s ‘rehabilitation revolution’ was first articulated, it encompassed innovation by frontline staff, by organisations working within a mixed economy and even social entrepreneurs. Under Transforming Rehabilitation, innovation remained a stated aim of probation reform, although the scope of innovation envisaged appeared to have narrowed. Innovation is also integral to ideas of evidence-based and evidence-led practice and there are numerous examples of innovative practice developing within probation and the wider criminal justice system. Applying the ‘innovation lens’ to evidence-based practice also raises interesting questions for the future development of such practice

The role of the arts, humanities and social sciences in forming and informing responses to contemporary social change

Modern, liberal societies face a number of overarching challenges: demographic changes, increasing inequality, unemployment and under-employment, political instability, austerity and ecological, social and economic unsustainability are challenging established paradigms of political-economy. Current political discourse emphasises market-based approaches to these stressors: we contend it is rather the disciplines of the social sciences, arts and humanities that have more to say about the resolution of these externalities. In the following we seek to broaden the discourse regarding the role of these disciplines in interpreting and beginning to address social challenges. Our consideration of human values as a complement of monetary values is illustrated practically by three indicative projects conducted by the authors. In each case, we focus on the qualitative impact of these disciplines’ approaches on the participants and their environment. We suggest these activities have transformative potential through providing a platform for reflexion, collaboration and the building of communities

Nested levels of adaptive divergence: the genetic basis of craniofacial divergence and ecological sexual dimorphism

Exemplary systems for adaptive divergence are often characterized by their large degrees of phenotypic variation. This variation represents the outcome of generations of diversifying selection. However, adaptive radiations can also contain a hierarchy of differentiation nested within them where species display only subtle phenotypic differences that still have substantial effects on ecology, function, and ultimately fitness. Sexual dimorphisms are also common in species displaying adaptive divergence and can be the result of differential selection between sexes that produce ecological differences between sexes. Understanding the genetic basis of subtle variation (between certain species or sexes) is therefore important for understanding the process of adaptive divergence. Using cichlids from the dramatic adaptive radiation of Lake Malawi, we focus on understanding the genetic basis of two aspects of relatively subtle phenotypic variation. This included a morphometric comparison of the patterns of craniofacial divergence between two ecologically similar species in relation to the larger adaptive radiation of Malawi, and male–female morphological divergence between their F2 hybrids. We then genetically map craniofacial traits within the context of sex and locate several regions of the genome that contribute to variation in craniofacial shape that is relevant to sexual dimorphism within species and subtle divergence between closely related species, and possibly to craniofacial divergence in the Malawi radiation as a whole. To enhance our search for candidate genes we take advantage of population genomic data and a genetic map that is anchored to the cichlid genome to determine which genes within our QTL regions are associated with SNPs that are alternatively fixed between species. This study provides a holistic understanding of the genetic underpinnings of adaptive divergence in craniofacial shape

Modularity of the Oral Jaws Is Linked to Repeated Changes in the Craniofacial Shape of African Cichlids

The African cichlids of the East-African rift-lakes provide one of the most dramatic examples of adaptive radiation known. It has long been thought that functional decoupling of the oral and pharyngeal jaws in cichlids has facilitated their explosive evolution. Recent research has also shown that craniofacial evolution from radiations in lakes Victoria, Malawi, and Tanganyika has occurred along a shared primary axis of shape divergence, whereby the preorbital region of the skull changes in a manner that is, relatively independent from other head regions. We predicted that the preorbital region would comprise a variational module and used an extensive dataset from each lake that allowed us to test this prediction using a model selection approach. Our findings supported the presence of a preorbital module across all lakes, within each lake, and for Malawi, within sand and rock-dwelling clades. However, while a preorbital module was consistently present, notable differences were also observed among groups. Of particular interest, a negative association between patterns of variational modularity was observed between the sand and rock-dwelling clades, a patter consistent with character displacement. These findings provide the basis for further experimental research involving the determination of the developmental and genetic bases of these patterns of modularity

Foraging environment determines the genetic architecture and evolutionary potential of trophic morphology in cichlid fishes

Phenotypic plasticity allows organisms to change their phenotype in response to shifts in the environment. While a central topic in current discussions of evolutionary potential, a comprehensive understanding of the genetic underpinnings of plasticity is lacking in systems undergoing adaptive diversification. Here, we investigate the genetic basis of phenotypic plasticity in a textbook adaptive radiation, Lake Malawi cichlid fishes. Specifically, we crossed two divergent species to generate an F3 hybrid mapping population. At early juvenile stages, hybrid families were split and reared in alternate foraging environments that mimicked benthic/scraping or limnetic/sucking modes of feeding. These alternate treatments produced a variation in morphology that was broadly similar to the major axis of divergence among Malawi cichlids, providing support for the flexible stem theory of adaptive radiation. Next, we found that the genetic architecture of several morphological traits was highly sensitive to the environment. In particular, of 22 significant quantitative trait loci (QTL), only one was shared between the environments. In addition, we identified QTL acting across environments with alternate alleles being differentially sensitive to the environment. Thus, our data suggest that while plasticity is largely determined by loci specific to a given environment, it may also be influenced by loci operating across environments. Finally, our mapping data provide evidence for the evolution of plasticity via genetic assimilation at an important regulatory locus, ptch1. In all, our data address long-standing discussions about the genetic basis and evolution of plasticity. They also underscore the importance of the environment in affecting developmental outcomes, genetic architectures, morphological diversity and evolutionary potential

1979 and All That: A forty-year reassessment of Margaret Thatcher’s legacy on her own terms

There is a growing disaffection with mainstream politics in the world’s liberal democracies. In particular, the UK has become an increasingly divided nation; as evidenced by, for example, increasing inequality, an emphasis on individualism, the so-called North/South divide and the polarised debate about the UK’s leaving the European Union. Many leading UK politicians claim inheritance of the “Thatcher legacy” to legitimate their proposed policies, yet it is not clear what is that legacy. Thatcher’s policies, instituted in the 1980s and broadly pursued by subsequent governments, changed the economic and social outlook of the UK. Criticism of her record is taken to indicate one is a left-wing ideologue. Our contribution in the following is that we judge Thatcher’s policies by no standards other than her own. Utilising an holistic approach, we consider whether neo-liberal policies facilitated or undermined the UK’s achieving Thatcher’s stated moral outcomes: the growth of democratic capitalism and the strengthening of the moral economy. We demonstrate, in contrast to contemporary narratives of her “saving the country”, the neo-liberal economic experiment has failed to deliver, even on Thatcher’s own terms. This analysis has contemporary domestic and global implications as generally Thatcherite policies continue to be applied in the UK and in other nations around the world

Hate crime in Suffolk : understanding prevalence and support needs

This research project was commissioned by the Suffolk Hate Crime Partnership with funding allocated to them from the Ministry of Justice. The aim of the project was to provide independent evidence of: • The prevalence of Hate Crime in Suffolk • The needs of victims • The support needs of communities affected by Hate Crim