15 research outputs found
BiologĂa de ConservaciĂłn, nuevas estrategias bajo diferentes perspectivas
- Publication venue
- 'Asociacion Española de Ecologia Terrestre (AEET)'
- Publication date
- 01/01/2002
- Field of study
En esta revisiĂłn presentamos una sĂntesis de los principales cambios conceptuales que han ido modelando una ciencia
relativamente joven como es la BiologĂa de ConservaciĂłn. La incorporaciĂłn de tĂ©cnicas y metodologĂas procedentes de
disciplinas prĂłximas ha sido uno de los factores que ha determinado la apertura de nuevas perspectivas en esta ciencia. El
desarrollo de nuevos paradigmas como el del desarrollo sostenible o las consideraciones prĂĄcticas recogidas en foros
internacionales como la Convención sobre Diversidad Biológica también han tenido una notable repercusión en su
desarrollo. En cualquier caso no parece oportuno olvidar que la BiologĂa de ConservaciĂłn es una disciplina de "crisis". Nos
enfrentamos a unas tasas de extinción y de pérdida de håbitats que no han sido conocidas con anterioridad a nivel
planetario. Es por ello que los biĂłlogos de conservaciĂłn deberĂamos tener siempre presente esta urgencia y las
administraciones responsables no deberĂan escatimar recursos en este sentido, convencidos como estamos de que la crisis
de biodiversidad tiene, y en un futuro prĂłximo seguirĂĄ teniendo, repercusiones en todas las esferas de la actividad humana.
En este sentido, serĂa un avance importante en nuestro paĂs la inclusiĂłn de un nuevo plan de I+D+I en nuestra estrategia
nacional de investigaciĂłn sobre BiologĂa de ConservaciĂłn
Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world
- Author
- Abad Pedro
- Abbara Suhny
- Abbasi Taimur
- Abbott Brian
- Abdel Aziz Islam Shawky
- Abdulla Jawdat
- Abikhzer Gad
- Abohashem Shady
- Abougabal Mahasen
- Abramson Sandra
- Abrihan Paz
- Acuña Arturo Romero
- Affandi Erwin
- Afzal Muhammad Shehzad
- Agolti Mariela
- Agranovich Svetlana
- Aguadé-Bruix Santiago
- Aguero Roberto Nicolas
- Ahmed Hassan Mohamed Ismail
- Ahmed Taghreed
- Akhter Afroza
- Al Dhuhli Humoud
- Al Kindi Faiza
- Al-Abboud Tarek
- Al-Bulushi Naeema
- Al-Mallah Mouaz
- Alak Maria del Carmen
- Alam Edison
- Alaoui Nadia Ismaili
- Alasnag Mirvat
- Albadr Amjed
- Albalooshi Batool
- Albano Domenico
- Alberguina Lucia Graciela
- Albernaz Siqueira Maria Helena
- Alexanderson-Rosas Erick
- Alfaro Ana
- Ali Mohamed Mandour
- Alkadhi Hatem
- Alkandari Faridah
- Allam Adel
- Allarakha Mohammad Aaftaab
- Almeida Augusto
- Almousalli Omar
- Alongi Pierpaolo
- Alonso Omar
- Alves Togni Paulo Henrique
- Alves Wilson Furlan
- Ananthasubramaniam Karthikeyan
- Anderson Jill
- Andrade Jose Henrique
- Andrade Luciana
- Angelidis George
- Anselmi Carlos
- Ansheles Alexey
- AraĂșjo Roberta
- Archontaki Aikaterini
- Arnone Gaspare
- Arnous Samer
- Arnson Yoav
- Arroñada Guillermo
- Arturo Harold
- Asano Hiroshi
- Ascani Sebastian Perez
- Asfour Ahmed
- Askew Jeffrey
- Assadi Majid
- Astesiano Alfredo
- Astesiano Andrea
- Attanasio Lea
- Atyani Said
- Ayala Sandra
- Ayetey Harold
- Ayodele Tolulope
- Azevedo Guilherme
- Bagatin Elisa
- Bailly Matthieu
- Baldari Sergio
- Balmer-Swain Mallory
- Bang Ji-In
- Banthia Nilesh
- Bar-Shalom Rachel
- Barette Rene
- Baric Ana
- Barneveld Peter
- Barragan Adriana Puente
- Barragan Erika
- Barroso Asela
- Basavaraj Ashok Gangasandra
- Batinic Tonci
- Batista Juan Felipe
- Batyrkhanov Daultai
- Bauckneht Matteo
- Baugh Dainia
- Bayer Richard R.
- Bedi Punit
- Bejai Shereen
- Ben-Rais Nozha
- Benedek Imre
- Benedek Theodora
- Benitez Luis
- Benlabgaa Rabie
- Bennie George
- Benteo Pablo
- Beretta Mario
- Berman Daniel S.
- Bernheim Adam
- Bertelli Paolo
- Bester Ria
- Bettencourt Nuno
- Better Nathan
- Better Nathan
- Beuzeville Scott
- Bezerra Sabbrina
- Bhagat Jinendra Kumar
- Bhargava Rishi
- Bhat Vivek
- Bhatia Mona
- Bhatti Sabha
- Biancardi Rodrigo
- Bianco Francesco
- Bieging Erik
- Biggans Thomas
- Bittencourt Marcio Sommer
- Blanco Isabel
- Blanco Juan
- Blankstein Ron
- Blankstein Ron
- Bloom Stephen
- Blue Sean
- Bluemke David
- Bluemke David A.
- Boktor Raef
- Bom Henry
- Bonelli Juan Manuel
- Bonfiglioli Rachele
- Boni Roberto
- Borges Andressa
- Bouyoucef Salah
- Branch Kelley
- BrandĂŁo Simone
- Bravo Paco
- Brothers Jessica
- Bruno Andrea
- Bruno Isabella
- BrÄten Anders Tjellaug
- Budoff Matthew
- Buechel Ronny Ralf
- Buga Klara
- Bularga Anda
- Bull Russell
- Bullock-Palmer Renée
- Burandt Angela
- Burg Samuel
- Burger Peter
- Burgul Rajesh
- Burke Floyd W.
- Bush Kelvin
- Busnardo Elena
- Bustos Jose Javier
- Butler Patrick
- Byrne Angela
- BĂžttcher Morten
- Cabada Manuel
- Cabeda Estevan Vieira
- Cabrejas Raul
- Cabrera Antonio
- Cachero Jorge
- Cadena Alberto
- Caicedo Carlos
- Calcott Jennifer
- Califaretti Elena
- Camarero Alicia
- Camoni Luca
- Campisi Roxana
- Canal Maria Pedrera
- Candela Candace
- Canderoli Alejandro
- Canessa Jose
- Cantinho Guilhermina
- Cao Dianbo
- Capasso Elizabeth
- Carames Silvia
- Carnevale Aldo
- Carpenter John-Paul
- Carr Loretta
- Carrascosa PatrĂcia
- Carreira Lara
- Carvajal-Juarez Isabel
- Casoni Roberta
- Castro Bruno
- Castro Gabriel
- Castro Ricardo
- CasĂĄns-Tormo Irene
- Cavalcante Joao
- Cavallo Armando Ugo
- Cavenaghi Giorgio
- Cendoya Oscar
- Cerci Rodrigo
- Cerci Rodrigo J.
- Ceriani Luca
- Chambers Duane
- Chan Virgil
- Chang Donald
- Chang Tien
- Chao Charles
- Chatterjee Saurav
- Chatziioannou Sofia
- Chatzizisis Yiannis
- Cheezum Michael
- Chen Jennifer
- Chen Marcus
- Chen Tiffany
- Cheung Stephen
- Chierichetti Franca
- Chimura Chimura Misato
- Chiocchi Marcello
- Cho Sang-Geon
- Choi Andrew
- Choi Andrew
- Choi Andrew D.
- Chong Woon
- Choudhury Partha
- Chow Benjamin
- Chowdekar Vijay Sai
- Christensen Mette
- Cittanti Corrado
- Clarcq James
- Cognigni Luciano Martin
- Cohen Yosef
- Cohen Yosef A.
- Coie Tchoyoson Lim
- Coles Duncan
- Collaud Carlos
- Collaud Carlos
- Colletta Mauro
- Concha Carmen
- Conti Umberto
- Cordero Ayreen
- Cortes Claudia
- Cortés Filiberto
- Cortés Violeta
- Cossu Alberto
- Courtis Javier
- Cragnolino Daniel
- Crim Matthew
- Cruz Eric
- Cuadra Teresa
- Cuellar-Calabria Hug
- Cunali Fernando
- Cuocolo Alberto
- Cury Roberto
- Cusack David
- Cuzzocrea Marco
- Dabreo Dominique
- Dai Xu
- Daicz Mariana
- Danciu Sorin
- Dantas Roberto
- Dariy Olga
- Datseris Ioannis
- Dautov Tairkhan
- de Amorim Fernandes Fernando
- De Boeck Bart
- De Carvalho Filipe Penna
- De La Peña Erasmo
- De La Vega Alejandro
- De Lorenzo Andrea
- De Macedo Filho Robson
- De Maria Silvia Teresa
- De Rimini Maria Luisa
- De Souza Thiago Ferreira
- De Vincentis Giuseppe
- Decter Bruce
- Del Giudice Eleonora
- Del Riego Horacio
- Del Torto Alberico
- Della Tommasina Veronica
- Deshpande Aparna
- Dettori Fernando
- Deux Jean-François
- Deviggiano Alejandro
- Dhruva Nimish
- Diaz Javier Lopez
- Djuraev Omoa
- Dobson Mark
- Doherty Neil
- Dondi Maurizio
- Dondi Maurizio
- Dorbala Sharmila
- Dorbala Sharmila
- Dougan John
- Doukky Rami
- Downie D'Arne
- Dragonetti Laura
- Drozdova Olga
- Dunbar Anjori
- Durmo Rexhep
- Duvall William
- Dwivedi Girish
- Edmond John
- Edwards Rachael
- Efros-Monsen Elen
- Einstein Andrew J.
- Einstein Andrew J.
- Elison Barry
- Ellis Chris
- Emami Farshad
- Embon Mario
- Engela Jean
- Engelbrecht Gerrit
- Engelmann Vaclav
- Enriquez Ruben Emilio
- Ensinas Jorge
- Erba Paola Anna
- Erthal Fernanda
- Escobar Manuel Valencia
- Escorza Velez Giovanni Alejandro
- Espeche Maria del Huerto Velazquez
- Esquitin Kerry
- Evangelista Laura
- Evbuomwan Osayande
- Faccio Fernando
- Facello Adolfo
- Fairbairn Timothy
- Faletti Riccardo
- Faragasso Evelina
- Faraggi Marc
- Farah Husam
- Farrugia Alexia
- Farsad Mohsen
- Fatima Shazia
- Fentanes Emilio
- Ferencik Maros
- Ferencik Maros
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- Ferreira Antonio
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- Fitzpatrick Daniel
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- Florimonte Luigia
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- Friedrich Matthias
- Fringuelli Fabio Massimo
- Fuentes Cañamero Maria Eugenia
- Fuisz Tony
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- Fujisue Koichiro
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- Fukushima Yoshimitsu
- Fukuyama Kae
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- Gaikwad Anand
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- Garg Ria
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- Gatti Marco
- Gaudiano Angela
- Georgoulias Panagiotis
- Geronazzo Ricardo
- Gerson Myron
- Gheysens Olivier
- Ghimire Ram Kumar
- Ghini Bruno
- Ghoshhajra Brian
- Gimelli Alessia
- Girijanandan Mahapatra Prof Dr
- Giubbini Raffaele
- Giuffrida Francesca
- Glaudemans Andor
- Gleeson Tadhg
- Goda Artan
- Goebel Benjamin
- Goebel Benjamin
- Goldberg Alan
- Goldner Brian
- Gomez Marie Rhiamar
- Gomez Sharon
- Goncalves Luiz
- Gong Lianggeng
- Gongxeka Harlem
- Gonza Natalia
- Gonzalez Carla
- Gonzalez Jorge
- GonzĂĄlez Luis
- GonzĂĄlez Ulises
- GonzĂĄlez-Montecinos Alejandro Becerril
- Goodwin Bruce
- Gopalan Deepa
- Gore Rosco
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- Gottlieb Ilan
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- Greenough Robert
- Grossman Gabriel Blacher
- GrÀni Christoph
- Gulyaev Vsevolod Milyevich
- Gummow Alistair
- Gunawan Gani
- Gutierrez Villamil Claudia T.
- Gutierrez Goleat
- Gutierrez Lucas
- Gutierrez Yamile Marcos
- Gutierrez Yamile Marcos
- Guzzo Miguel Angel
- Guzzo Miguel Angel
- GĂłmez Lauchy Juan Manuel
- Habets Jesse
- Habouzit Vincent
- Hadlich Marcelo
- Hafez Mohammed Nassoh
- Hage Fadi
- Haidar Mohamad
- Haider Agha
- Haider Sofia
- Hamilton Mark
- Hamilton-Craig Christian
- Hamirani Yasmin
- Han Dan
- Hapkido Habusari
- Harbinson Mark
- Hartley Thomas
- Hasbak Philip
- Hasbani Victor
- Hashimoto Jun
- Hassan Alia
- Hassan Mona
- Hassen Karen
- Hatfield Mallory
- Hawkins Carolyn
- Hawthorne Katie
- Heath Nicholas
- Hendel Robert
- Hernandez Phillip
- HernĂĄndez Gertrudis Sabatel
- Herrera Yariela
- Hess SĂžren
- Hidalgo Pablo
- Hidayat Basuki
- Hildre Dimmen Jenni-Mari
- Hill Gregory
- Hinterleitner Gerd
- Hirschfeld Cole B.
- Hirschfeld Cole B.
- Holdgaard Paw
- Homans Filip
- Hong Chae Moon
- Horgan Stephen
- Hou Yang
- Houshmand Golnaz
- Hsieh Victar
- Hua Shaw
- Huda Aulia
- Hudson Benjamin
- Huerin Melina
- Huffman Jeff
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- Jeong Yong Hyu
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- Jiménez-Santos Moisés
- Johansen Allan
- Johnson Chris
- Johnson Kerryanne
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- JĂžrgensen Arve
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- Kaplan Mitchell
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- Kumar Sukriti
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- Lee Ken
- Lee Kenneth
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- Leipsic Jonathon
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- Leppo Jeffrey
- Lesser John
- Leta Rubén
- Leung Eugene
- Leung Steve
- Leva Lucia
- Lewin Howard
- Lewkowicz Julio Manuel
- Li Caiying
- Li Dong
- Li Sijin
- Li Tao
- Liga Riccardo
- Liguori Carlo
- Lima Adna
- Lima Ronaldo
- Litmanovich Diana
- Liu Hui
- Liu Jinkang
- Liu Yiyan
- Londoño Blair Juan Luis
- Londoño Juan
- Longo Giampiero
- Lopes Rafael Willain
- Lopez-Mattei Juan
- Lopez-Mattei Juan
- Lopez-Mattei Juan
- Lotti Jose Maria
- Louw Lizette
- Lovera Cesar
- Low Chen
- Lu Bin
- Lu Bin
- Lu Yao
- Lugassi Rachel
- Luis Rodrigues Jonathan Carl
- Lumbreras Luis
- Luna Hiram Rivera
- LĂžvhaugen PĂ„l
- Machado e Silva Ricardo
- Madu Chibuzo
- Madu Ernest
- Maffione Margherita
- MagalhĂŁes Tiago
- Magboo Vincent Peter
- Magnussen John
- Magurany Kathleen
- Mai Nghi
- Mai Son Hong
- Majstorov Venjamin
- Mak Sze Mun
- Makhdomi Khalid
- Malan Nico
- Maldonado Alejandro
- Maleki Majid
- Malkovskiy Eli
- Malkovskiy Eli
- Mancini Maria Elisabetta
- Mander Gordon
- Manders Jeroen
- Manka Robert
- Mansy Ahmad
- Maor Moalem Israel Shlomo
- Marcassa Claudio
- Markowitz Jeremy
- Marn Amanda
- Marousa Ntouskou
- Maroz-Vadalazhskaya Natallia
- Marquez Alejandra
- Marquez-Cabeza Juan Javier
- Martin Francisco
- Martin Jon
- Martinez de Alegria Anxo
- Maruno Hirotaka
- Masoli Osvaldo
- Masoli Osvaldo Horacio
- Massardo Teresa
- Mastrocola Luiz Eduardo
- Mastrovito Edgardo
- Mataciunas Mindaugas
- Mataki Hiroyuki
- Matis Stephen E.
- Matos Luis
- Matushita Cristina SebastiĂŁo
- Maurice Hany
- Maurovich-Horvat PĂĄl
- Maurovich-Horvat PĂĄl
- Mayoraz Matias
- Mcalindon Elisa
- Mckenna Michael
- Mcrae Tony
- Medakovic Petar
- Medeiros FĂĄbio
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- Medina John Michael
- Medjahedi Abdelkader
- Meehan Conor
- Melado Graciela Eva
- Mele Anibal
- Mendoza Fernando
- Meneghetti José Claudio
- Menezes de Siqueira Maria Eduarda
- Menezes Leon
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- Merani Maria Fernanda
- Meretta Alejandro Horacio
- Merhige Michael
- Mesquita ClĂĄudio Tinoco
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- Milos Katarina
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- Moroi Masao
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- Mrsic Zorana
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- Murphy Mark
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- Pascual Thomas N. B.
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- Randazzo Michael J.
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- Saadullah Mohammad
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- Saifullina Guzaliya
- Saito Masaki
- Sakanyan Mari
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- Sambuceti Gianmario
- Samuel Anthony
- San Miguel Lucas
- Sanches Adelina
- Sandoval Sigelinda
- Santana Sara
- Sara da Silva Leonardo
- Sarai Masayoshi
- Saranovic Dragana Sobic
- Sarda-Mantel Laure
- Sasse Alexander
- Sato Daisuke
- Satyr Maryna
- Saunders Connor
- Saxena Sudhir
- Sayman Haluk
- Sazonova Svetlana
- Scarano Massimo
- Scarlett Luke
- Schemmer Mary
- Schmidt Erzsébet
- Schneider Roman P.
- Schoepf U. Joseph
- Schofield Rebecca
- Scholte Arthur
- Scholtens AsbjĂžrn
- Scholtz Leonie
- Schvartzman Paulo
- SciagrĂ Roberto
- Sebikali Mugisha Julius
- Sekar Ramkumar
- Sellem Ali
- Semple Thomas
- Seneviratne Sujith
- Sengupta Shantanu
- Senra Tiago
- Sereegotov Erdenechimeg
- Sergienko Vladimir
- Sergienko Vladimir
- Sevilla Ana
- Shaaban Mahmoud
- Shah Nishant
- Shah Nishant R.
- Shah Samir
- Shalev Aryeh
- Shanbhag Sujata
- Sharma Gaurav
- Sharma Naveen
- Shaw Leslee J.
- Shaw Leslee J.
- Shayani Steven
- Shetty Deepa
- Shiozaki Afonso
- Shiraishi Shinya
- Shirani Jamshid
- Shirka Ervina
- Shivaram Pushpa
- Shrestha Ganesh
- Shulman Jonathan
- Shurupova Irina
- Sierra-Galan Lilia M.
- Sierra-Galan Lilia M.
- Sigman Steven
- Silva FĂĄbio Martins
- Simanek Milan
- Simon Mitch
- Simonsson Magnus
- Singh Bhanupriya
- Singh Santosh
- Sinitsyn Valentin
- Siqueira Cristiano
- Siu Silvia
- Slart Riemer
- Slim Ahmad
- Small Gary
- Smanio Paola
- Smith Alexandra
- Smith David
- So Young
- Soares Carlos Eduardo
- Soeriadi Erwin Affandi
- Solanki Vijay
- Solari Lucrecia
- Soldat-Stankovic Valentina
- Soli Idrissa Adamou
- Soman Prem
- Sood Aditya
- Sood Ashwani
- Sperandio Massimiliano
- Spiro Bernardo
- Srichai-Parsia Monvadi Barbara
- Stan Claudiu Adrian
- Stankovic Sinisa
- Stanton Tony
- Stavrou Petros
- Stefanelli Antonella
- Steffensen Rolf
- Strada Bruno
- Streeter James
- Strouhal Peter
- Stuart Murch
- Stubbs Michael
- Subedi Deepak
- Sueldo Claudio Pereyra
- Sun Kai
- Suwa Yoshinobu
- Swainson Ian
- Syawaluddin Hilman
- Syed Ghulam
- Szilveszter Balint
- T Albert
- Tacher Vania
- Tag Naima
- Takanami Kentaro
- Takehana Kazuya
- Taki Junichi
- Taleb Sara
- Tamaki Nagara
- Tandon Vikas
- Tang Gongshun
- Tang Jeanelle Margareth
- Taniguchi Yasuyo
- Taubman Kim
- Tawakol Ahmed
- Taylor Andrew
- Tecson Bettina
- Teragawa Hiroki
- Theng Youdaline
- Thientunyakit Tanyaluck
- Thimister Paul
- Thomas Dustin
- Thomas Paul
- Thomassen Anders
- Thompson Randall
- Thu Phyo Si
- To Andrew
- Tomas Miguel Santaularia
- Tomizawa Nobuo
- Topping William
- Torbet Tara
- Torreao Jorge
- Torres Rafael
- Traverso Sonia
- Traverzo Sonia Simona
- Trifonova Tatjana
- Trinidad Desiree
- Trivedi Adwait
- Tsujita Kenichi
- Tweed Katharine
- Udugama Chandraguptha
- Uellendahl Marly
- Ullery Shawn
- Umeji Kyoko
- Unger Steven
- Unzek Samuel
- Upton Anthony
- Uretsky Seth
- Uson Kristine Joy
- Ussov Wladimir Yurievich
- Uusitalo Valtteri
- Uy Mila
- Vajauskas Donatas
- Vakhromeeva Margarita
- Valiullina Nailya
- Vallejo Enrique
- Valles Mario
- Vallurupalli Srikanth
- Vallée Jean-Paul
- Valsamaki Pipitsa
- Vamadevan Shankar
- Van Asperen Erik-Jan
- Van De Heyning Caroline M.
- Van Gaal William
- Van Pelt Niels
- Vangu Mboyo
- Vargas Luis Salazar
- Vasquez Andres
- Vavlukis Marija
- Velez Mayra Sanchez
- Veltman Niels
- Ventroni Guido
- Vergel Damiana
- Verjans Johan
- Verma Atul
- Verma Vikas
- Verschure Derk
- VerĂssimo OtĂĄvia
- Villines Todd C.
- Villines Todd C.
- Vitola Joao V.
- Vitola Joao V.
- Vondrak Andrej
- Voutnis Demetrius
- Vuuren Magritha Jv
- VĂĄrady Edit
- VĂĄzquez Manuel Castillo
- Wagenaar Nils
- Wakabayashi Yasushi
- Waller Alfonso
- Waltrick Roberto
- Wang Ellen
- Wang Jian
- Wang Ximing
- Wang Yifan
- Wang Yining
- Wang Zhao-Qian
- Ward Parker
- Wayne Victor
- Weihmuller Juan Sebastian
- Weir-Mccall Jonathan
- Weiss Konrad
- Weissman Gaby
- Wesbey George
- White James
- White Kelly
- Williams Michelle C.
- Williams Michelle C.
- Wilson Peter
- Winchester David
- Winchester David
- Wolcan Juan
- Wolinsky David
- Won Kyoung Sook
- Wong David
- Wong Kirby
- Wu Jiang
- Wu Zhifang
- Xia Liming
- Xiao Jiangxi
- Xu Lei
- Xu Zhuoran
- Yamada Shinichiro
- Yamazaki Shinya
- Yang Youyou
- Yew Min Sen
- Yin Wu
- Yoneyama Tatsuya
- Yost Sandra
- Young Calum
- Younger John
- Younis Muhammad Numair
- Yu Jianqun
- Yuan Li
- Zaid Eed Abu
- Zakavi Seyed Rasoul
- Zapparoli Marcello
- Zavadovsky Konstantin
- Zeffiro Susana
- ZeidĂĄn Nahla
- Zerahn Bo
- Zgaljardic Michael
- Zhang Longjiang
- Zhang Tong
- Zhang Xiaoli
- Zhang Yong-Gao
- Zhu Li
- Zhuravlev Kirill
- Zoboli Stefania
- Zukotynski Katherine
- Zuluaga Alejandro
- Ăvrehus Kristian Altern
- Ć talc Monika
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic.
Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality.
Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States.
Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis.
Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection
Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study
- Author
- A. Mohammed Kalakwa
- A. Nemer Ayoub
- Abantanga Francis A.
- Abatli Safa' Jamal
- Abbas Wisam
- Abbo Olivier
- Abdelbaqi Reem
- Abdelhady Dina Sobhy
- Abdelhafez Mohammad Omar Mohammad
- Abdelhamid Sultan S.
- Abdelmaksoud Sherif
- Abdelmoumen Roua
- Abdelmutalib Fakereldeen
- Abdul-Mumin Alhassan
- Abduljawad Fatima Mousa
- Abdullah Fizan
- Abdullah Mohd Yusof bin
- Abdulraheem Nurudeen
- Abdulrahman Alaa
- Abdulsalam Moruf Adekunle
- Abdunomonovich Dekhkonboev Avazjon
- Aboelela Ahmed
- Abouheba Mohamed
- Abrahamsson Kate
- Abrunhosa Matias Marcia
- Abu-Nejmah Fawzi
- Abuajaila Abdulsalam
- Abuattaya Adham Ashraf
- Abubakar Auwal M
- Abueideh Ahmad
- Abuhayyeh Husam Aldean
- Abuhlega Ma'aly A.
- Abukhalaf Sadi
- Abumunshar Ali Abdelhay
- Acuna Gaston
- Adams Stephen
- Adamu Sani
- Adanan Mohd Fitri Shukri bin Mohamed
- Adawi Ihda
- Adawi Samer
- Adawy Ahmad
- Ade-Ajayi Niyi
- Adegboyega Rilwan
- Ademuyiwa Adesoji
- Adesanya Opeoluwa
- Adhiwidjaja Cathline Freya
- Adofo-Ansong Nana
- Agboola Titiloye Hannah
- Agelebe Efeturi
- Aguilar Aguilar Faye
- Aguilar Gargurevich Prince Pamela
- Aguirre-Lopez Pastor
- Agulham Miguel Angelo
- Ahmad Hira
- Ahmad Zahidah Adlynee Haji
- Ahmed Hazem
- Ahmed Mahmoud Abdelfattah
- Ajai Olalekan Temitope
- Ajao Emmanuel Akinlabi
- Ajiboye Olalekan S.
- Ajrami Yara
- Ajwa Ahmad Elian Abu
- Akan M. Eren
- Akhbari Melika
- Akhter Nadeem
- Akova Fatih
- Al-Attar Hala M.
- Al-Halbouni Layana
- Al-Mamun Abdullah
- Al-Mayoof Ali Farooq
- Al-Momani Hashem M.
- Al-Mouakeh Ahmad
- Al-Rayyes Maisara
- Al-saleem Hasan Subhi Hasan Abu
- Al-Salhi Ashraf Ayman
- Al-Shwaikh Samar H.
- Al-Slaibi Ibrahim
- Al-Taher Raed Nael
- Al-Taher Raed Nael
- Al-Tammam Hiba
- Alakaloko Felix
- Alamrain Abdulwhhab Ayman Abu
- Alanguia Chipana Cathy Lee
- Alattas Khalid
- Alberto Carlos
- Albozidi Aya
- AlcĂĄntara Elvyn
- ALDIRAWI MOHAMMED A. M.
- Alebbini Mohanad Mutasem
- Alfoghi Mabroka
- Algabri Hayder Nadhim Obaid
- Alglaib Mohammed Meftah
- Alhamid Ahmad
- Alhamid Aos
- Alhassan Priscilla
- Ali Hassan
- Ali Karim Osamy
- Ali Liza
- Ali Mansour
- Alijla Sharif
- Alijla Sharif S.
- Aliwisat Ahmad Hasan
- Aljaboo Hajir
- Aljadidi Wesal Omar F. Saied
- Aljarad Ziad
- Alkareem Raghad mohammad abdu
- Almada Suad Ahmed
- Almadhoun Walaa
- Almasri Murad
- Almeida Aguiar Arthur
- Almeida Giovana
- Almengar Inas
- Almohamady Hisham
- Almosaibli Mohammad
- Almusleh Tasneem Fathi Hasan
- Alnaeri Ali
- Alnahhal Khaled
- Alonso VerĂłnica
- Alosta Hasan Mustafa
- Alqarajeh Firas
- Alqor Mohammad Omar Ibrahim
- Alsaadi Nijmeh Nasser
- Alsaggaf Ameen
- Alsaied Amer
- Alser Mohammed
- Alser Osaid H.
- Alshaikhkhalil Haya Abdulnasser Ali
- Alshehri Abdullah
- Altaweel Ahmed
- Altın Merve
- Altokhais Tariq
- Altomi Mohamed
- Alturki Fahad
- Alvarado Zelada Jackelyne
- Alves Dutra da Silva Ărika
- Alwadia Soha Marwan Salem
- Alwaggaa Nouriyah Ali
- Alzamari Ainaa Ata Mohammad
- Alzate Gallego Edgar
- Alzeer Asmahan Mohammad Suliman
- Alzerei Sulaiman T.
- Alzraikat Sayel H.
- Alzubair Afnan
- Alzughayyar Tareq Z.
- Amad Mohamed
- Amado Fernando
- Amaechi Chukwubinyelum
- Amah Christopher Chim
- Amarin Justin Z.
- Amarin Marzouq
- Ambriz-GonzĂĄlez Gabriela
- Ameh Emmanuel
- Amjad Muhammad Bin
- Amoabin Afua Amoabin
- Anatole Nzanzu
- Anatole Nzanzu Kipata
- Anaya Dominguez Marlene
- Anaya Firas
- Andrade Jerhy
- Andreussi Lorna
- Anicama Elias Rocio
- Annajjar Mohammad hasan
- Anntinea Jessmine
- Antunes Amanda
- Antunez-Mora Alexandra
- Anyomih Theophilus Teddy Kojo
- Anzelewicz Stefan
- Apaza Leon Jose Luis
- Appeadu-Mensah William
- Arabiat Esraa
- Arafa Mohamed Ahmed
- Arafat Hasan
- AragĂŁo Liliana
- Arancibia Gutiérrez Elsa
- Aranda SĂĄnchez Cristian Irela
- Arar Ahmad Samih
- Arauco Jenny
- Arbab Hana
- Arboleda Jenny
- Aremo Anuoluwapo
- ArnadĂłttir Helena
- Arnaud Alexis P
- Arnold Marion
- Arnoletto Lucia Beatriz
- Arrmali Saddam
- Arrmalli Lina Ali
- Arshad Muhammad
- Arthur Felicity
- Arul Suren
- Ashour Dina Ayman
- Ashour Yara shareef
- Aslan Yakup
- Aspirot Ann
- Assi Ahmadfateh
- Assi Muath Abdelrahem Fuad
- Astudillo Miguel
- Atatri Yazid yousef mahmoud
- Atta Ahmed
- Attia Alaa Mobarak
- Avile Romina
- Avolio Luigi
- Awad Hadeel
- Aydin Emrah
- Aykut Merve
- Ayque Rosas Fernando
- Aziz Dayang Anita Abdul
- Ba'baa' Basheer
- Badr Helmy
- Baertschiger Reto
- Bagbio Dominic
- Bah Abdoulie
- Bai Qiang
- Bai Yu Zuo
- Baistrocchi Valentina
- Bakar Ainal Huda Abu
- Baker Wisam
- Ballouhey Quentin
- Balousha Abrar ghassan
- Bamanga Ahmed
- Baniowda Muath A. M.
- Bao Xiaozhou
- Barauskas Vidmantas
- Barbosa Patricia Reis
- Baseggio Natalia
- Bashir Fatma
- Bashir Muhammad Kashif
- Bassan Gonçalves Paulo César
- Bataineh Ziad A.
- Batal Mohammad Mohannad
- Bazozi Hana Milad
- Beasley Spencer
- Becker Karin
- Belmino Gadelha AluĂsio Augusto
- Benaskeur Yousra-Imane
- Beres Alana
- BerkovĂĄ KlĂĄra
- Bernaus Marianela
- Berrocal Anaya Waldo
- Berzanskis Mindaugas
- Beshtawi Doha mustafa saleh
- BeĆir Ahmet
- Bianchin Ezequiel
- Bibas Fatma
- Biber Elna
- Bischoff Cristiano
- Bismarck Sylvester von
- Blain Otilia Eva
- Blanc Thomas
- Blazquez-Gomez Eva
- Bobadilla Morales Lucina
- Bode Christopher
- Bonnard Arnaud
- Boonthai Ampaipan
- Borbonet Daniel
- Bouhadiba Nordeen
- Bowder Alex
- Bracho Blanchet Eduardo
- Bradshaw Kate
- Bragagnini Paolo
- Brahmamdam Pavan
- Bravo Mauro Nicolas
- Bright Benedict Paul
- Brito Quevedo Luz Mery
- Broch Aline
- Brolin Santis Isolan Paola Maria
- Brunero Marco
- Bruxel Carla Luisa
- Bsisu Isam
- Bucaram Elena
- Bueno Mazzuca Rafael
- Bueno Motter Sarah
- Bujarimin Ahmad Shafiee bin
- Bulnes Mendizabal David
- Burks Stephen S.
- Burns Kate
- Butler Marilyn
- Bvulani Bruce
- C. Nwosu David
- Caamal Lorenzo Juvencio
- Calancea Calin
- Calderon Moore Antonio
- Calderón Arancibia José Alfredo
- Calistus Nwachukwu
- Cama Jitoko
- Camamra Kajali
- Cameron Fraser
- Camp Lauren
- Canözer Ali
- Caouette-Laberge Louise
- Cardenas Alva Loreley Raquel
- Cardenas Ruiz Velasco Juan Jose
- Carrasco Ana Lucia
- Carrasco-Ortega Cesar
- Carrillo Isabel
- Casado Francis Tanise
- Casal Beloy Isabel
- Caseb Paloma
- Casquero Victor
- Castañeda Espinosa Sergio
- Castaño Avila Daniela
- Castedo Camacho Fabiola Ruth
- Cavaiuolo Silvia
- Cañapataña Sahuanay Veronica Raquel
- Cepeda Rodrigo
- Cesur İlknur Banlı
- Chan Jonathan
- Chang Jeremy
- Charras Maria Delia
- Chaudary Ali Raza
- Chaudhry Muhammad Amjad
- Chauhan Nirav
- Chavez Galvez Patricia
- Chen Lulu
- Chen Rui
- Cheung Maija
- Chipalavela Rossana Francisco
- Chiriboga Elena
- Chitiavi Soita Wycliffe
- Chitnis Milind
- Cho Seok Hyeon
- Choo Candy SC
- Chukwu Isaac
- Chukwuemeka Anyanwu Lofty-John
- Chung Jae Hee
- Cletus Cyril
- Coghill Griffin
- Collins Nwokoro
- Colombo de Holanda Felipe
- Contreras Carla Sofia
- Coon John
- Cordonnier Annelien
- Cornelli Fabio
- Cornwall Hannah
- Corona C. Rivera Jorge RomĂĄn
- Corona Rivera Alfredo
- Correa Leite Mila Torii
- Correa Armandou
- Correa Catalina
- CorrĂȘa Costa Eduardo
- Cosoreanu Vlad
- Costas-Chavarri Ainhoa
- Cripovich Alejandrina
- Cunningham Aaron
- Czauderna Piotr
- CĂĄceres Aucatoma Freud
- CĂĄrdenas BarĂłn JosĂ© de JesĂșs
- Cömert Hatice Sonay Yalçın
- da Silva Augusto Maria Lucia
- DagilytÄ RĆ«ta
- Dahman Nesrine Ben Hadj
- Dajia Wang
- Dalek Noor Fa'izatul Rahil Ambok
- Dallegre Maria Belen
- Dalloul Hisham
- Damiani Andrea
- Dammagh Nagham Mohammed Al
- Dania Bouguermouh
- Darras Osama Majed
- Darwish Ahmed S
- Darwish Ammar
- Dass Anthony
- Dassonville Martine
- Davenport Kate
- David Kuria
- Davies Justine
- Davis Jenna Kylene
- de Assis Silva Murilo
- de Azevedo Belesa Flavia
- de Campos Vieira Abib Simone
- de Deus Passos Leles Kamila
- de Guzman Johann
- de Souza Santos Ferreira Mariana
- Dedeke Florence
- Defago Victor Hugo
- Defert Coralie
- Delefortrie Thomas
- Delforge Xavier
- Delft Dirk von
- Delgado Malaga Florangel Patricia
- Delgado Quinteros Edgar Fernando
- Dellenmark Blom Michaela
- Dendusic Nejra
- Derbew Miliard
- Derks Terry
- Deya Corazone
- Deyab Abdelaziz
- Di Siervi Oscar
- Diaz Castañeda Flor de Maria
- Diaz Echegaray Marlene
- Diaz Gomez Jose Manuel
- Diaz Leon Cesar
- Dieudonné Lemfuka
- Dimatatac Doris Mae
- Djordjevic Ivona
- Dogar Sohail
- Doheim Mohamed Fahmy
- Dominguez Danny
- Donglai Hu
- Dornellas do Nascimento Suely
- dos Santos Dias André Ivån Bradley
- Dosselman Luke J.
- Douiri Abdel
- Drah Weam
- Dube Andile Maqhawe
- Duchesne Camille
- Duggan Eileen
- Duote Cai
- Dure Carolina
- DĂĄvila Perez Roberto
- Ebeido Annan
- Egbuchulem Ifeanyichukwu Kelvin
- Ejinkeonye Eze Chukwuemeka
- Ekenze Sebastian Okwuchukwu
- Ekwunife Okechukwu Hyginus
- El-Ghazaly Mohammed
- Elassall Gena Mohamed Hamed
- Elayeb Abdallah
- Elebute Olumide Abiodun
- Elewaily Mohamed
- Elfiky Mahmoud
- Elgammudi Mala
- Elghazaly Shrouk Mahmoud
- Elhadi Ahmed
- Elhadi Muhammed
- Elhajjaji Yasmine Ali
- Elhattab Ahmad
- Elisante Joseph
- Elkaloush Abdullahn Abdousalam
- Elkhazmi Ebtesam Othman Abdulsalam
- Elmenam Mohamed Abd
- Elmzyyen Aya Mahmoud
- Elrais Safa Abdal
- Elsadek Menan Ahmed
- Elsaied Adham
- Elshaer Omar Adly
- Elsherbiny Mohamed
- Elsiraffy Omar Ossama
- Elstad Maria
- Elzohiri Mohamed
- Elzowawi Fathi
- Emam Omar Sameh
- Emil Sherif
- Enbaya Manal Ben
- Ensar Nicholas
- Erdem Melisa
- Eren Elif
- Ergenekon Ebru
- EroÄlu Egemen
- Erturk Nazile
- Erçin Seçil
- Eshkabilov Shukurali
- Espineda Beda
- Essa Tarek Mohamed
- Essamilghi Kamila Almabrouk Mohammed
- Ezidiegwu Ugochukwu S
- Ezomike Uchechukwu Obiora
- Faboya Omolara Moronkeji
- Fachin Camila
- Fadhle Muhamed Jassim
- Faks Vivian
- Falah Eyad Hassan
- Farag Eman mohamed
- Fares Jehad
- Farha Mervat Sufian Abu
- Farion-Aguiar Luiz
- Fawzy Omar Moustafa
- Fayez Mohamed
- Fazli Mohamad Rafi
- Feldens Leticia
- Felix Michael
- Ferdousi Tamanna
- Fernandes de Oliveira Darli
- Fernandes de Souza Rachel
- Fernandez Ferrer Marianelly
- Fernandez Portilla Emilio
- Fernandez Wilson Miriam Daniela
- Ferraz Schopf Luciano
- Flores Carbajal Lenny
- Ford Kat
- Forero Ladino Angelica Maria
- Fouda Mohamed Fayez
- Fouly Mariam Albatoul Nageh
- Fouquet-Languillat Virginie
- Fourcade Laurent
- Fowler Kathryn L
- Fox Sarah
- Franco Helena
- Furtado Meyer Karine
- Furtado Mariana
- FĂ©liz Erick
- Gabriel Comba
- Gad Dalia
- Gadepalli Samir
- Gai A.
- Galdeano Marcelo
- Gall Caroline Le
- Gamage Tharanga
- Gamboa Kcomt Segundo
- Gao Zhigang
- Gao Zhou Chong
- Garcia Martinez Humberto
- Garcia Isidora
- Garcia Virginia
- Garcia-Aparicio Luis
- GarcĂa Miriam
- Gargum Sondas Ali
- Garnier Hanna
- Garrett-Cox Robin
- Gasana Georges
- Gatzinsky Vladimir
- Gavrila Bogdan
- Gavrilovska-Brzanov Aleksandra
- Gee Oliver
- Gerus Sylwester
- Geze ĆĂŒkran
- Ghabayen Amir Talat Sheda
- Ghallab Alaa
- Ghaly Khaled Abd elrahman
- Ghanem Waleed H.
- Ghayth Sumayyah
- Ghazzawi Ihsan
- Ghilardi Silva Ximena
- Ghorab Islam Abdelmonem
- Ghosh Dhruv
- Gilardi Jose
- GirĂŁo Tauffer Mariana
- Goddard Lucy
- Goebel Peter
- Gohil Hetal
- Gomes Adriano Luis
- Gomez Juanita
- Gomez Oscar
- Gondal Mudassir Fayaz
- Gonzales Brandy
- Gonzalez Cortez Luis Fernando
- Gonzalez Daniel Emilio
- Gonzalez Joann
- GonzĂĄlez Ojeda Alejandro
- Gonçalves Borges Carolina
- Gonçalves da Cunha
- Gonçalves Victor
- Gosain Ankush
- Grabowski Andrzej
- Granéli Christina
- Greenberg Jodie
- Grella Maria Giovanna
- Grosos CĂ©line
- Grottling Emma
- Grynberg Lucie
- Guadagno Elena
- Guayelema Marisol
- Guazzotti Marinella
- Guerin Florent
- GuimarĂŁes Patricia
- Guinsburg Ruth
- Guisse Carmen
- Gurgel do Amaral Antonio Cipriano
- Gurskas Pranas
- Gutarra Palomino Andrea
- Gutierrez Maldonado Joan Elizabeth
- Habiba Alouani
- Hagander Lars
- Hagander Lars
- Haidari Sayed Aman
- Haider Naveed
- Hajajreh Ma'alem sameer
- Hakan Nilay
- Halabi Yasmeen Adly
- Hall Nigel
- Hall Timothy
- Hameed Soban
- Hamidi Nadia
- Hamidovic Ajla
- Hamill James
- Hamilton April
- Hammato Abdalkarim Yhya
- Hammond Philip
- Hammouri Ahmad G.
- Hamzah Siti Nur Aien binti Hamid
- Han Yijiang
- Hanifah Nur Atiqah binti Mohd
- Haraux Elodie
- Harilal Shamaman
- Harper Luke
- Hasan Samiul
- Hasan Samiul
- Hasanain Doaa Khalil
- Hashim Hidayah Hayati binti
- Hashim Imran
- Hashim Sophia
- Hassan Majd Yousef Mohammed
- Hassan Mohamed Abada
- Hassan Mohd Razin bin
- Hassan Zulfitri bin Md
- Herappe Mellado Dorihela
- Herdan Mohamed Omar
- HernĂĄndez CĂłrdova Karina
- Herrera Pesara Luciana Martina
- Herrera Carina
- Herrera Laura
- Hery GĂ©raldine
- Hinostroza Daniel
- Hisham Intisar
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- Vaquila Justo
- Varela Maria Florencia
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- Venkatraman Soundappan Sannappa
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- Villalba Villalba Araceli
- Villegas Silva RaĂșl
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- Vosoughi Armin
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- Wishah Nidal
- Wissanji Hussein
- Wolak Przemyslaw
- Wolny Agnieszka
- Wong Janice
- Wong Marilyn
- Wright Naomi Jane
- Wu Guowei
- Wyrzykowski Dariusz
- Xiaodong Guo
- Xie Hua
- Yacoub Mina A.
- Yaghi Bashar
- Yaghi Dua Hasan
- Yalcinkaya Ali
- Yang Hee-Beom
- Yanis Ahmad H.
- Yanowsky Reyes Guillermo
- Yao Yang
- Yapo Benjamin
- Yarza FernĂĄndez Jessica
- Yeniay Aslı ĂztĂŒrk
- Yola Mariya Mukhtar
- Yong Feng
- Youn Joong Kee
- Yousuf Hina
- Yu Mengnan
- Yu Raisa
- Yuen Quah Soong
- Yuldashev Rustam Z.
- Yunus Aayenah
- Za'nouneh Faris J. Abu
- Zaghlol Louay Y.
- Zahari Dato' Dr Zakaria bin
- Zain Mostafa
- Zaman Azrina SK
- Zanellato Josiane Bernartt
- Zarwawi Ahmad Zulhisyam bin
- Zea-Salazar Luis Enrique
- Zeinelabdeen Ali
- Zhao Xiaoxia
- Zhu Jianming
- Zhu Libin
- Zidan Mazen
- Zivanovic Dragoljub
- Zottis Barcelos Fabricio
- Zreeg Dafer abdulhakim . S.
- Zurikat Rajai O.
- Zvizdic Nada
- Zvizdic Zlatan
- Ăekiç Bahanur
- Ăelik MĂŒge
- Ăzçelik Zerrin
- Ćeref Kıvanç
- Ć afus AntonĂn
- Ć kvaĆil Jan
- Ć tichhauer Radek
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
Summary
Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally.
Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies
have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of
the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income
countries globally, and identified factors associated with mortality.
Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to
hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis,
exomphalos, anorectal malformation, and Hirschsprungâs disease. Recruitment was of consecutive patients for a
minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical
status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary
intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause,
in-hospital mortality for all conditions combined and each condition individually, stratified by country income status.
We did a complete case analysis.
Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital
diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal
malformation, and 517 with Hirschsprungâs disease) from 264 hospitals (89 in high-income countries, 166 in middleincome
countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male.
Median gestational age at birth was 38 weeks (IQR 36â39) and median bodyweight at presentation was 2·8 kg (2·3â3·3).
Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income
countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups).
Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome
countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries;
pâ€0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients
combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88â4·11],
p<0·0001; middle-income vs high-income countries, 2·11 [1·59â2·79], p<0·0001), sepsis at presentation (1·20
[1·04â1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention
(ASA 4â5 vs ASA 1â2, 1·82 [1·40â2·35], p<0·0001; ASA 3 vs ASA 1â2, 1·58, [1·30â1·92], p<0·0001]), surgical safety
checklist not used (1·39 [1·02â1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed
(ventilation 1·96, [1·41â2·71], p=0·0001; parenteral nutrition 1·35, [1·05â1·74], p=0·018). Administration of
parenteral nutrition (0·61, [0·47â0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65
[0·50â0·86], p=0·0024) or percutaneous central line (0·69 [0·48â1·00], p=0·049) were associated with lower mortality.
Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome,
middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will
be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger
than 5 years by 2030
Observation of gravitational waves from the coalescence of a 2.5â4.5 Mâ compact object and a neutron star
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- Yin X.
- Yokoyama Jun'ichi
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- Yu Hang
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- Zhao Yuhang
- Zheng Yanyan
- Zhong Haowen
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- Zweizig John
- ĂrpĂĄd Gergely LĂĄszlĂł
- ć ćæŹœ
- éœäžž éèĄ
- Publication venue
- Publication date
- 23/04/2024
- Field of study
Ultralight vector dark matter search using data from the KAGRA O3GK run
- Author
- Abac A. G.
- Abbott R.
- Abe H.
- Abouelfettouh I.
- Acernese F.
- Ackley Kendall
- Adamcewicz Christian
- Adhicary S.
- Adhikari Naresh
- Adhikari Rana X.
- Adkins V. K.
- Adya V. B.
- Affeldt C.
- Afif Ismail M.
- Agarwal Deepali
- Agathos Michalis
- Aguiar Odylio D.
- Aguilar I.
- Aiello Lorenzo
- Ain Anirban
- Ajith Parameswaran
- Akseli Hannuksela Otto
- Akutsu Tomotada
- Al-Jodah Ammar
- Al-Shammari S.
- Albanesi S.
- Alberto Trani Alessandro
- Alfaidi Reem Atallah E
- Allocca Annalisa
- Alléné C.
- Altin Paul
- Alvarez-Lopez Sofia
- Amato Alex
- Amez-Droz L.
- Amorosi A.
- Amra C.
- Anand S.
- Ananyeva A.
- Anderson Stuart
- Anderson Warren G.
- Andia Manuel
- Ando M.
- Andrade T.
- Andrea Prodi Giovanni
- Andres Nicolas
- Andric Tomislav
- Andrés-Carcasona Marc
- Anglin J.
- Anne Bizouard Marie
- Ansoldi S.
- Antelis Javier M.
- Antier Sarah
- Antoni Ramis Vidal Felip
- Antonietta Palaia Maria
- Antonio Font Roda Jose
- Aoumi M.
- Appavuravther E. Z.
- Appert S.
- Apple S. K.
- Arai Koji
- Araya Akito
- Araya Melody
- Areeda Joseph
- Argianas L. Granda
- Arif Shaikh Md
- Aritomi Naoki
- Armato F.
- Arnaud Nicolas
- Arogeti Megan
- Aronson Scott
- Arun K. G.
- Ashton Gregory
- Aso Yoichi
- Assiduo M.
- Aston S. M.
- Astone Pia
- Aubin Florian
- AVALLONE Guerino
- Babak Stanislav
- Badaracco Francesca
- Badger C.
- Bae Sangwook
- Bagnasco Stefano
- Bagui E.
- Bai Y.
- Baier Jeremy
- Bajpai Rishabh
- Baka T.
- Ball M.
- Ballardin G.
- Ballmer S. W.
- Banagiri Sharan
- Banerjee Biswajit
- Bankar Deepak
- Baral Pratyusava
- Barayoga J. C.
- Barish B. C.
- Barker D.
- Barneo Pablo
- Barone Fabrizio
- Barr Bryan
- Barsotti Lisa
- Barsuglia Matteo
- Barta DĂĄniel
- Barthelmy S. D.
- Barton Mark Andrew
- Bartos I.
- Basak Soummyadip
- Basalaev Artem
- Bassiri Riccardo
- Basti Andrea
- Bawaj Mateusz
- Baxi P.
- Bayley Joseph
- Baylor Amanda
- Bazzan M.
- Bedakihale V. M.
- Beirnaert Freija
- Bejger MichaĆ
- Belardinelli Daniele
- Bell Angus
- Benedetto V.
- Beniwal D.
- Benoit William
- Bentley Joe
- Bera Sayantani
- Berbel Marina
- Bergamin Fabio
- Berger Beverly
- Bernuzzi Sebastiano
- Beroiz Martin
- Bersanetti Diego
- Bertolini A.
- Betzwieser Joseph
- Beveridge Damon
- Bevins Nathaniel
- Bhandare R.
- Bhardwaj Uddipta
- Bhatt R.
- Bhattacharjee Dripta
- Bhaumik Shubhagata
- Bhowmick S.
- Bianchi A.
- Bilenko I. A.
- Billingsley GariLynn
- Binetti Alberto
- Bini Sophie
- Birnholtz Ofek
- Bisht A.
- Bitossi Massimiliano
- Blackburn Kent
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- Blair D. G.
- Bobba F.
- Bode Nina
- Bogaert G.
- Boileau Guillaume
- Boldrini Mattia
- Bolingbroke Georgia
- Bolliand A.
- Bondarescu Ruxandra
- Bondu François
- Bonilla Carrasquel Edgard
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- Bonnand Romain
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- Bossilkov V.
- Boudart Vincent
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- Braglia Matteo
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- BRANCHESI Marica
- Breschi Matteo
- Briant Tristan
- Brillet A.
- Brinkmann M.
- Brockill P.
- BrockmĂŒller Eike
- Brooks Aidan
- Brown D. D.
- Brunett S.
- Bruno G.
- Bruntz Robert
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- Bucci F.
- Buchanan J.
- Bulashenko Oleg
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- Bulten H. J.
- Buonanno Alessandra
- Burtnyk K.
- Buscicchio Riccardo
- Buskulic D.
- Bustillo J. CalderĂłn
- Buy Christelle
- Byer R. L.
- BĂ©csy Bence
- C. Utina Andrei
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- RAZZANO MASSIMILIANO.
- Read J.
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- schwartz eyal
- Scott Jamie
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- Sekiguchi Yuichiro
- Sellers D.
- Sengupta Anand
- Sentenac D.
- Seo Eungwang
- Sequino V.
- Sergeev A.
- SERRA Marco
- Servignat Gaël
- Shaffer T.
- Shah Urja
- Shahriar Selim
- Shams B.
- Shao Lijing
- Shapiro Key Joey
- Sharan Salafia Om
- Sharma A. K.
- Sharma P.
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- Shawhan Peter
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- Shen B.
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- Shikauchi M.
- shimode katsuhiko
- Shinkai Hisa-aki
- Shiota J.
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- Shoemaker Deirdre
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- SINGH MUKESH. KUMAR.
- Singha Ayatri
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- Somiya Kentaro
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- soni siddharth
- Sordini V.
- Sorrentino F.
- Sorrentino Nunziato
- Soulard R.
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- Spagnuolo V.
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- Spera Mario
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- Srivastava A. K.
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- STEER DaniĂšle
- Steffano Bonilla Marceline
- Steinlechner J.
- Steinlechner Sebastian
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- Szewczyk PaweĆ
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- Tacca Matteo
- Tagoshi Hideyuki
- Tait Simon
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- Torres Forne Alejandro
- Torrie C. I.
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- Tosta e Melo Iara
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- TRAPANANTI Angela
- Travasso Flavio
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- Tripathee Aashish
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- Turconi Margherita
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- Uehara Tomoyuki
- Ueno Koh
- Unnikrishnan C. S.
- Ushiba Takafumi
- Vacatello Michele
- Vahlbruch Henning
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- Vajente Gabriele
- Vajpeyi A.
- Valdes Guillermo
- Valencia J.
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- Vallejo-Peña S. A.
- Vallero S.
- Valsan Vinaya
- Valérie Martinez
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- van Beuzekom Martin
- van Dael Mathyn
- Van de Walle A.
- van den Brand Johannes
- Van Den Broeck C.
- van der Sluys Marc
- van Dongen Jesse
- Van Haevermaet Hans
- van Heijningen Joris
- van Putten Maurice
- Van Ranst Zeb
- van Remortel Nick
- Vander-Hyde D. C.
- Vandra K.
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- Vardaro M.
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- varma vijay
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- vecchio alberto
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- Veitch John
- Veitch Peter
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- Verdier Patrice
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- Vinet J. -Y.
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- Weizmann Kiendrebeogo R.
- Weller C. M.
- Weller Robert
- Wellmann F.
- Wen L.
- Wette Karl
- WeĂels P.
- Whelan John
- White D. D.
- Whiting Bernard F.
- Whittle Chris
- Wildberger J. B.
- Wilk O. S.
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- Won Seo Jin
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- Wright Mick
- Wu Chien-Ming
- Wu David S.
- Wu Hsun-Chung
- Wysocki Daniel
- Xiao Liting
- Xu Victoria
- Xu Yumeng
- Yaala M. Ben
- Yadav Nikesh
- Yakovlev Alexey
- Yamamoto Hiroaki
- Yamamoto Kazuhiro
- Yamamoto M.
- Yamamoto Takahiro
- Yamamoto Takahiro S.
- Yamamura S.
- Yamazaki Ryo
- Yan S.
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- Yarbrough Zach
- Yeh S. -W.
- Yelikar A. B.
- Yeung S. M. C.
- Yin X.
- Yokoyama Jun'ichi
- Yokozawa T.
- Yoo Jooheon
- Yu Hang
- Yuzurihara Hirotaka
- ZadroĆŒny A.
- Zahoor Jan Aasim
- Zannelli A. J.
- Zanolin M.
- Zeeshan M.
- Zelenova T.
- Zendri J. -P.
- Zeoli M.
- Zerrad M.
- Zevin Michael
- Zhang A. C.
- Zhang Jue
- Zhang L.
- Zhang Rui
- Zhang T.
- Zhang Ya
- Zhao C.
- Zhao Yue
- Zhao Yuhang
- Zheng Yanyan
- Zhong Haowen
- Zhong S.
- Zhou R.
- Zhu Zong-Hong
- Zucker M. E.
- Zweizig John
- ĂrpĂĄd Gergely LĂĄszlĂł
- ć ćæŹœ
- æčćšéź
- éœäžž éèĄ
- Publication venue
- Publication date
- 01/03/2024
- Field of study
Among the various candidates for dark matter (DM), ultralight vector DM can be probed by laser interferometric gravitational wave detectors through the measurement of oscillating length changes in the arm cavities. In this context, KAGRA has a unique feature due to differing compositions of its mirrors, enhancing the signal of vector DM in the length change in the auxiliary channels. Here we present the result of a search for U(1)BâL gauge boson DM using the KAGRA data from auxiliary length channels during the first joint observation run together with GEO600. By applying our search pipeline, which takes into account the stochastic nature of ultralight DM, upper bounds on the coupling strength between the U(1)BâL gauge boson and ordinary matter are obtained for a range of DM masses. While our constraints are less stringent than those derived from previous experiments, this study demonstrates the applicability of our method to the lower-mass vector DM search, which is made difficult in this measurement by the short observation time compared to the auto-correlation time scale of DM
Aplicación de espacios wiki como herramienta de aprendizaje colaborativo en la enseñanza universitaria
- Author
- Publication venue
- RELADA - Revista ElectrĂłnica de ADA-Madrid
- Publication date
- 01/12/2009
- Field of study
Los espacios wiki proporcionan a los estudiantes una herramienta sencilla para participar en la construcciĂłn de los contenidos de la asignatura, proporcionando informaciĂłn asĂ como discusiones sobre temas predefinidos. En Septiembre de 2007 establecimos un espacio wiki llamado MEDICON orientado a proporcionar una experiencia de aprendizaje colaborativo en asignaturas relacionadas con la conservaciĂłn de la biodiversidad y evaluar las posibilidades de esta herramienta. Esta iniciativa ha obtenido una respuesta entusiasta por parte del alumnado con una participaciĂłn activa de alrededor del 80%. Las secciones de noticias de conservaciĂłn y glosario de tĂ©rminos han sido las que han experimentado un mayor desarrollo y han contado con un mayor nĂșmero visitas. Durante los cuatro meses de duraciĂłn de esta experiencia las pĂĄginas de este espacio han recibido mĂĄs de 5500 visitas y mĂĄs de 800 sesiones de ediciĂłn. La evaluaciĂłn de esta experiencia por parte de los alumnos ha sido muy positiva
Colonialism in the periphery: Spanish linguistic policy in New Granada, c. 1574â1625
- Author
- Arroyo Luis
- Bataillon Marcel
- Burkhart Louise M.
- Cañeque Alejandro
- CerrĂłn Palomino Rodolfo
- Cobo Betancourt Juan Fernando
- Durston Alan
- Dussel Enrique
- DĂŒmmler Christiane
- Estenssoro Fuchs Juan Carlos
- Estenssoro Fuchs Juan Carlos
- Fabian Johannes
- Friede Juan
- Gamboa Jorge Augusto
- GonzĂĄlez de PĂ©rez MarĂa Stella
- Greer Margaret Rich
- Itier CĂ©sar
- Itier CĂ©sar
- Itier CĂ©sar
- Juan Fernando Cobo Betancourt
- Konetzke Richard
- Lamana Gonzalo
- Lee LĂłpez Alberto
- Lee LĂłpez Alberto
- Lisi Francesco Leonardo
- Lugo Bernardo de
- Lugo Bernardo de
- MartĂnez MarĂa Elena
- Medina José Toribio
- Ortega Ricaurte Carmen
- Ospina SuĂĄrez Pedro Antonio
- Ostler Nicholas
- Pacheco Juan Manuel
- Pacheco Juan Manuel
- PachĂłn Ximena
- Pardo Osvaldo F.
- Rafael Vicente L.
- Real Cuesta Javier
- Resines Luis
- Restrepo Posada José
- RodrĂguez-Salgado MarĂa JosĂ©
- Romero Mario GermĂĄn
- Rosenblat Ăngel
- Rozo Gauta José
- Salomon Frank
- Sicroff Albert A.
- Tanner Norman
- Taylor Gerald
- Triana y Antorveza Humberto
- Triana y Antorveza Humberto
- Triana y Antorveza Humberto
- Zapata de CĂĄrdenas Fray Luis
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
The burden of mild asthma: Clinical burden and healthcare resource utilisation in the NOVELTY study
- Author
- Adams Frances
- Al-Asadi Loâay
- AndĂșjar RubĂ©n
- Anees Syed
- Anholm James
- Anoro Laura
- Arboleda Alejandra,
- Aries Sven,
- Averill Frank
- Baines Stuart
- Bals Robert
- Bansal Sandeep
- Baptist Alan
- Barbetta Carlo
- Beasley Richard
- Beck Ekkehard
- Bell Alan
- Bendstrup Elisabeth
- Benhabib Gabriel
- Bertley John
- Boersma Willem
- Bolivar Grimaldos Fabio
- Bonniaud Philippe
- Bowler Simon
- Bradman Drew
- Braido Fulvio
- Bremner Peter
- Broughton Emma
- Brun Olivier
- Brunstad Ole,
- Bueno Carlos,
- Bull Sheetal
- Burgel Pierre-RĂ©gis
- Campbell Colin
- Campo MatĂas Felix,
- Campos Michael,
- Campos Sergio
- Cançado José,
- Cardaci Vittorio
- Cardoso Alexandre,
- Carroll Patrick
- Castilla MartĂnez Manuel
- Chaalan Mariam
- Chang Yoon-Seok
- Cheema Amarjit
- Chen Meihua
- Chen Yan
- Chipps Bradley
- Cho Young,
- Chouaid Christos
- Chouinard Guy
- Clini Enrico,
- Comeche Casanova Lorena
- Corbacho Dolores
- Corral Gloria,
- Corzo Marco,
- Cosgrove John
- Costantino Maria,
- Couturaud Francis
- Crook Gretchen
- Csanadi Michael
- Cunha ThĂșlio
- Curiac Dan
- Cuttitta Giuseppina
- de Blic Jacques
- de Llano Luis,
- Debieuvre Didier
- Deimling Andreas
- Deleon Samuel
- Delsart Dominique
- Demaegdt Axelle
- Demoly Pascal
- Deschildre Antoine
- Devouassoux Gilles
- Dhar Anil
- Dhillon Ripple
- Di Gioacchino Mario
- Djamin R.S.
- DomĂnguez Peregrina Alfredo
- Echave-Sustaeta Jose
- Egron Carole
- Eid Alain
- Eijsvogel Michiel
- Einvik Gunnar
- Endo Takeo
- Epstein Ellen
- Falchero Lionel
- Farah Claude
- Feimer Jan
- Fernandez Marta,
- Fitzgerald J,
- Flood-Page Patrick
- Fois Alessandro
- Foschino-Barbaro Maria,
- Franssen Frits
- Fritz Stephen
- Fujita Masaki
- Fuller Elizabeth
- Gamboa Setién Pedro
- Gammeri Enrico
- GarcĂa Clemente Marta
- GarcĂa Salmones Mercedes
- GarcĂa MarĂa,
- GarcĂa-Navarro Alvar,
- Golam Sarowar,
- Goosens Martijn
- Goupil François
- Graat-Verboom Lidwien
- Grimm-Sachs Vera
- Groth Gesine
- Gu Wei
- Hammerschlag Gary
- Hancock Kerry
- Hara Yu
- Harrington Zinta
- Harris Hoadley
- Harrison Tim
- Hartley David
- Hattotuwa Keith
- Herth Felix
- Hewitt Mitzie
- Hilberg Ole
- Hoheisel Gerhard
- Holguin Fernando
- Horiguchi Takahiko
- Hosoi Keita
- Hudes Golda
- Hughes Rod
- Hui Kim,
- Hwang Yong,
- HĂžines Kristian,
- Ide Yumiko
- Inchingolo Riccardo
- Inomata Minehiko
- Inoue Hiromasa
- Inoue Koji
- Inoue Sumito
- Jackson Richard
- Janson Christer
- Janssen Rob
- Javier Ruth,
- Jones Gareth
- Kanawaty David
- Kanniess Frank
- Kato Motokazu
- Katsoulotos Gregory
- Kaufman Alan
- Kaufman David
- Kawasaki Masayuki
- Kawayama Tomotaka
- Kelly Allan
- Kessler Romain
- Khusrawi Alamdar
- Killorn William
- Kim Joshua
- Kim Woo,
- Kita Toshiyuki
- Kjellerup Carsten
- Klapholz Ari
- Kobayashi Kanako
- Koh Young-Il
- Koto Hiroshi
- Krishna Harshavardhan
- Kuppens Kim
- Landry Daniel
- Langton David
- Lavorini Federico
- Le Roux Pascal
- Lee Byung-Jae
- Lee Daria
- Lee Donald
- Lee Kwan-Ho
- Lee Sang-Pyo
- Lee Yong,
- Lewis Keir
- Li Manxiang
- Li Shiyue
- Lienert Thomas
- Lif-Tiberg Cornelia
- Lim Seong,
- Lima Marina
- Lin Robert
- Lisanti Raul,
- Luton Robert
- Luts Anders
- Ma Lijun
- Mabire Pascal
- Mahay Guillaume
- Maldonado Francisco,
- Mandhane Piushkumar
- Marino Gustavo
- Martinez Stéphanie
- MarĂn Trigo Jose,
- Maselli-Caceres Diego
- Mattarucco Walter
- Mcgarvey Lorcan
- Mcivor Andrew
- Mehta Vinay
- Melloni Boris
- Min Kyung,
- Molina de Salazar Dora
- Molino Antonio
- Montano Gonzalez EfraĂn
- Moreau Laurent
- Morice Alyn
- Moy James,
- Mozo Paloma,
- Mronga Silke
- MĂŒllerovĂĄ Hana
- Nishi Koichi
- Nogueira Juan
- Nucera Eleonora
- Nwokoro Ugo
- NĂșñez Ignacio,
- Oh Yeon-Mok
- Oien Torbjorn
- Olaguibel José,
- Olmo Ricardo,
- Palomo Sara,
- Pandya Preeti
- Papi Alberto
- Parikh Purvi
- Parikh Sudhir
- Park Choon-Sik
- Park Hae-Sim
- Park Heung-Woo
- Parody Maria
- Pascale Pablo
- Patel Manish
- Patella Vincenzo
- Pek Bonavuth
- Perrino Frank
- Pesci Alberto
- Peters Matthew
- Petrella Robert
- Prassad Lakshman
- Pueyo Bastida Ana
- Qin Guangyue
- Rabahi Marcelo
- Raherison Chantal
- RamĂrez-Venegas Alejandra
- Rapsomaniki Eleni
- Rañó Ana
- Reddel Helen,
- Reig Albert,
- Reinhardt Jörg
- Rendon Adrian
- Rhee Chin,
- Ricciardolo Fabio
- Rivera José Olaguibel
- Riviere Emilie
- Robaina Jose,
- Rodriguez Pablo
- RodrĂguez GonzĂĄlez-Moro JosĂ©
- Rogliani Paola
- Rolon Roxana,
- Roux-Claudé Pauline
- Roy Kay
- Ruhlmann James
- Ruiz Xavier,
- Rustscheff Stefan
- RĂ„hlen Lennart
- Sadatsafavi Mohsen
- Saito Junpei
- Sajkov Dimitar
- Santiago Francis
- Sarzani Riccardo
- Sassoon Catherine
- Sathyamurthy Ramamurthy
- Schlenska Christian
- Serrano Carolina,
- Settipane Russell,
- Shimizu Yasuo
- Shirai Toshihiro
- Silva Damian
- Simpson Frederick,
- Song Weidong
- Soulier Michel
- Sousa Daniel
- Sriram Peruvemba
- Stollery Daniel
- Stolpe Christoph
- Sugihara Naruhiko
- Svetliza Graciela
- Tai Sze
- Takahashi Ken-Ichi
- Tan Wei
- Tang Yijun
- Tashimo Hiroyuki
- Teber Ishak
- Thiagarajan Swaminathan
- Thomas Paul
- Timmermann Hartmut
- Tomii Keisuke
- Turner Alice
- Ulrich Thomas
- van de Ven Mario
- van den Berge Maarten
- Vancheri Carlo
- Veen Johannes,
- Velasco Garrido José
- Velling Peter
- Vestbo Jorgen
- Victorio Carlos,
- Vignal Guillaume
- Vincenti Rigoletta
- Wachs Richard
- Wang Chen
- Wang Tan
- Wark Peter
- Wedzicha Wisia
- Wehgartner-Winkler Sabina
- Weinreich Ulla
- Welling Juergen
- Wen Fuqiang
- Wilkinson Tom
- Wilson Pete
- Winkelmann Ernst-Joachim
- Wu Feng
- Xiang Pingchao
- Xiao Zuke
- Xiong Shengdao
- Yaici Azzedine
- Yamada Takashi
- Yanai Masaru
- Yang Jinghua
- Yang Jingping
- Yañez Anahi
- Yoon Ho,
- Yoon Hyoung-Kyu
- Zhang Caiqing
- Zhang Min
- Zhang Ping
- Zhang Wei
- Zheng Xiaohe
- Zhu Dan
- Publication venue
- 'Elsevier BV'
- Publication date
- 09/05/2022
- Field of study
Background: Patients with mild asthma represent a substantial proportion of the population with asthma, yet there are limited data on their true burden of disease. We aimed to describe the clinical and healthcare resource utilisation (HCRU) burden of physician-assessed mild asthma.Methods: Patients with mild asthma were included from the NOVEL observational longiTudinal studY (NOVELTY; NCT02760329), a global, 3-year, real-world prospective study of patients with asthma and/or chronic obstructive pulmonary disease from community practice (specialised and primary care). Diagnosis and severity were based on physician discretion. Clinical burden included physician-reported exacerbations and patient-reported measures. HCRU included inpatient and outpatient visits.Results: Overall, 2004 patients with mild asthma were included; 22.8% experienced â„1 exacerbation in the previous 12 months, of whom 72.3% experienced â„1 severe exacerbation. Of 625 exacerbations reported, 48.0% lasted >1 week, 27.7% were preceded by symptomatic worsening lasting >3 days, and 50.1% required oral corticosteroid treatment. Health status was moderately impacted (St George's Respiratory Questionnaire score: 23.5 [standard deviation ± 17.9]). At baseline, 29.7% of patients had asthma symptoms that were not well controlled or very poorly controlled (Asthma Control Test score <20), increasing to 55.6% for those with â„2 exacerbations in the previous year. In terms of HCRU, at least one unscheduled ambulatory visit for exacerbations was required by 9.5% of patients, including 9.2% requiring â„1 emergency department visit and 1.1% requiring â„1 hospital admission.Conclusions: In this global sample representing community practice, a significant proportion of patients with physician-assessed mild asthma had considerable clinical burden and HCRU
Treatable traits in the NOVELTY study
- Author
- Adams Frances
- AgustĂ Alvar
- Al-Asadi Lo'Ay
- Anderson Gary
- AndĂșjar RubĂ©n
- Anees Syed
- Anholm James
- Anoro Laura
- Arboleda Alejandra Cañas
- Aries Sven Philip
- Averill Frank
- Baines Stuart
- Bals Robert
- Bansal Sandeep
- Baptist Alan
- Barbetta Carlo
- Bastida Ana Pueyo
- Beasley Richard
- Beck Ekkehard
- Bell Alan
- Bendstrup Elisabeth
- Benhabib Gabriel
- Bertley John
- Boersma Willem
- Bonniaud Philippe
- Bowler Simon
- Bradman Drew
- Braido Fulvio
- Bremner Peter
- Broughton Emma
- Brun Olivier
- Brunstad Ole Petter
- Bueno Carlos Matiz
- Bull Sheetal
- Burgel PierreârĂ©gis
- Campbell Colin
- Campos Michael
- Campos Sergio
- Cançado José Eduardo Delfini
- Cardaci Vittorio
- Carroll Patrick
- Casanova Lorena Comeche
- Chaalan Mariam
- Chang Yoonâseok
- Cheema Amarjit
- Chen Meihua
- Chen Yan
- Chipps Bradley
- Cho Young Joo
- Chouaid Christos
- Chouinard Guy
- Clemente Marta GarcĂa
- Clini Enrico Maria
- Corbacho Dolores
- Corral Gloria Francisco
- Corzo Marco FernĂĄndez
- Cosgrove John
- Costantino Maria Teresa
- Couturaud Francis
- Crook Gretchen
- Csanadi Michael
- Cunha ThĂșlio
- Curiac Dan
- Cuttitta Giuseppina
- de Blic Jacques
- de Llano Luis PĂ©rez
- de Salazar Dora Molina
- Debieuvre Didier
- Deimling Andreas
- del Olmo Ricardo
- Deleon Samuel
- Delsart Dominique
- Demaegdt Axelle
- Demoly Pascal
- Deschildre Antoine
- Devouassoux Gilles
- Dhar Anil
- Dhillon Ripple
- Di Gioacchino Mario
- Djamin R.
- Echave-Sustaeta Jose
- Egron Carole
- Eid Alain
- Eijsvogel Michiel
- Einvik Gunnar
- Endo Takeo
- Epstein Ellen
- Falchero Lionel
- Faner Rosa
- Farah Claude
- Feimer Jan
- Fernandez Marta Nuñez
- Fitzgerald J. Mark
- Flood-Page Patrick
- Fois Alessandro
- Foschino-Barbaro Maria Pia
- Franssen Frits
- Fritz Stephen
- Fujita Masaki
- Fuller Liz
- Gammeri Enrico
- GarcĂa MarĂa BuendĂa
- GarcĂa-Navarro Alvar Agusti
- Garrido José Velasco
- Gonzalez EfraĂn Montano
- GonzĂĄlez-Moro JosĂ© RodrĂguez
- Goosens Martijn
- Goupil François
- Graat-Verboom Lidwien
- Grimaldos Fabio Bolivar
- Grimm-Sachs Vera
- Groth Gesine
- Gu Wei
- Hammerschlag Gary
- Hancock Kerry
- Hara Yu
- Harrington Zinta
- Harris Hoadley
- Harrison Timothy
- Hartley David
- Hattotuwa Keith
- Herth Felix
- Hewitt Mitzie
- Hilberg Ole
- Hoheisel Gerhard
- Holguin Fernando
- Horiguchi Takahiko
- Hosoi Keita
- Hudes Golda
- Hughes Rod
- Hui Kim Ming Christopher
- Hwang Yong Il
- HĂžines Kristian Jong
- Ide Yumiko
- Inchingolo Riccardo
- Inomata Minehiko
- Inoue Hiromasa
- Inoue Koji
- Inoue Sumito
- Jackson Richard
- Janson Christer
- Janssen Rob
- Javier Ruth Cerino
- Jones Gareth
- Kanawaty David
- Kanniess Frank
- Kato Motokazu
- Katsoulotos Gregory
- Kaufman Alan
- Kaufman David
- Kawasaki Masayuki
- Kawayama Tomotaka
- Kelly Allan
- Kessler Romain
- Khusrawi Alamdar
- Killorn William
- Kim Joshua
- Kim Woo Jin
- Kita Toshiyuki
- Kjellerup Carsten
- Klapholz Ari
- Kobayashi Kanako
- Koh Youngâil
- Koto Hiroshi
- Krishna Harshavardhan
- Kuppens Kim
- Landry Daniel
- Langton David
- Lavorini Federico
- Le Roux Pascal
- Lee Byungâjae
- Lee Daria
- Lee Donald
- Lee Kwanâho
- Lee Sangâpyo
- Lee Yong Chul
- Lewis Keir
- Li Manxiang
- Li Shiyue
- Lienert Thomas
- Lif-Tiberg Cornelia
- Lijun Ma
- Lim Seong Yong
- Lima Marina
- Lin Robert
- Lisanti Raul Eduardo
- Luton Robert
- Luts Anders
- Mabire Pascal
- Mahay Guillaume
- Make Barry
- Maldonado Francisco Casas
- Mandhane Piushkumar
- Marino Gustavo
- Martinez Stéphanie
- MartĂnez Manuel Castilla
- Maselli-Caceres Diego
- Mattarucco Walter
- MatĂas Felix del Campo
- Mcgarvey Lorcan
- Mcivor Andrew
- Mehta Vinay
- Melloni Boris
- Min Kyung Hun
- Molino Antonio
- Moreau Laurent
- Morice Alyn
- Moy James
- Mozo Paloma Campo
- Mronga Silke
- MĂŒllerovĂĄ Hana
- Nishi Koichi
- Nogueira Juan
- Nucera Eleonora
- Nwokoro Ugo
- NĂșñez Ignacio GarcĂa
- Oh Yeonâmok
- Oien Torbjorn
- Palomo Sara Nuñez
- Pandya Preeti
- Papi Alberto
- Parikh Purvi
- Parikh Sudhir
- Park Choonâsik
- Park Haeâsim
- Park Heungâwoo
- Parody Maria
- Pascale Pablo
- Patel Manish
- Patella Vincenzo
- Pavord Ian
- Pek Bonavuth
- Peregrina Alfredo DomĂnguez
- Perrino Frank
- Pesci Alberto
- Peters Matthew
- Petrella Robert
- Pinto Cardoso Alexandre
- Prassad Lakshman
- Price David
- Qin Guangyue
- Rabahi Marcelo
- Raherison Chantal
- RamĂrez-Venegas Alejandra
- Rapsomaniki Eleni
- Rañó Ana
- Reddel Helen
- Reig Albert Roger
- Reinhardt Jörg
- Rendon Adrian
- Rhee Chin Kook
- Ricciardolo Fabio
- Rivera José Olaguibel
- Riviere Emilie
- Robaina Jose GarcĂa
- Rodriguez Pablo
- Rogliani Paola
- Rolon Roxana Willigs
- Roux-Claudé Pauline
- Roy Kay
- Ruhlmann James
- Ruiz Xavier Bocca
- Rustscheff Stefan
- RĂ„hlen Lennart
- Sadatsafavi Mohsen
- Saito Junpei
- Sajkov Dimitar
- Salmones Mercedes GarcĂa
- Santiago Francis
- Sarzani Riccardo
- Sassoon Catherine
- Sathyamurthy Ramamurthy
- Schlenska Christian
- Serrano Carolina Cisneros
- Setién Pedro Gamboa
- Settipane Russell
- Shimizu Yasuo
- Shirai Toshihiro
- Silva Damian
- Simpson Frederick Graham
- Song Weidong
- Soulier Michel
- Sousa Daniel
- Sriram Peruvemba
- Stollery Daniel
- Stolpe Christoph
- Sugihara Naruhiko
- Svetliza Graciela
- Tai Sze
- Takahashi Kenâichi
- Tan Wei
- Tang Yijun
- Tashimo Hiroyuki
- Teber Ishak
- Thiagarajan Swaminathan
- Thomas Paul
- Timmermann Hartmut
- Tomii Keisuke
- Trigo Jose Maria MarĂn
- Turner Alice
- Ulrich Thomas
- van de Ven Mario
- van den Berge Maarten
- Vancheri Carlo
- Veen Johannes
- Velling Peter
- Vestbo JĂžrgen
- Victorio Carlos
- Vignal Guillaume
- Vincenti Rigoletta
- Wachs Richard
- Wang Chen
- Wang Tan
- Wark Peter
- Wedzicha Wisia
- Wehgartner-Winkler Sabina
- Weinreich Ulla
- Welling Juergen
- Wen Fuqiang
- Wilkinson Tom
- Wilson Pete
- Winkelmann Ernstâjoachim
- Wu Feng
- Xiang Ping Chao
- Xiao Zuke
- Xiong Shengdao
- Yaici Azzedine
- Yamada Takashi
- Yanai Masaru
- Yang Jinghua
- Yang Jingping
- Yañez Anahi
- Yoon Ho Joo
- Yoon Hyoungâkyu
- Zhang Caiqing
- Zhang Min
- Zhang Ping
- Zhang Wei
- Zheng Xiaohe
- Zhu Dan
- Publication venue
- 'Wiley'
- Publication date
- 01/11/2022
- Field of study
CorrigendumVolume 27, Issue 12, Respirology, pages: 1095-1095. First Published online: November 6, 2022 10.1111/resp.14406International audienceAsthma and chronic obstructive pulmonary disease (COPD) are two prevalent and complex diseases that require personalized management. Although a strategy based on treatable traits (TTs) has been proposed, the prevalence and relationship of TTs to the diagnostic label and disease severity established by the attending physician in a real-world setting are unknown. We assessed how the presence/absence of specific TTs relate to the diagnosis and severity of 'asthma', 'COPD' or 'asthmaâ+âCOPD'
New insights into the genetic etiology of Alzheimerâs disease and related dementias
- Author
- Aaltonen Lauri
- Aaltonen Vesa
- Aarsland Dag
- Aavikko Mervi
- Abalos Mariana Sanchez
- Abdelnour Carla
- Abner Erin
- Abraham Richard
- Adams Hieab
- Adams Perrie M.
- Adarmes-GĂłmez Ad
- Adarmes-GĂłmez Astrid D.
- Aguilera Nuria
- Aguilera Nuria
- Aguirre Alyssa
- Ahmad Shahzad
- Akinyemi Rufus O.
- Al-Chalabi Ammar
- AlarcĂłn-MartĂn Emilio
- Albert Marilyn S.
- Albin Roger L.
- Alcolea Daniel
- Alegret Montserrat
- Ali Muhammad
- Allen Mariet
- Allende Irene Rosas
- Alonso MarĂa Dolores
- Alonso MarĂa Dolores
- Alvarez Ignacio
- Alvarez Lisa
- Amer-Ferrer Guillermo
- Amin Najaf
- Amouyel Philippe
- Anastasiou Anna
- Anastasiou Costas
- Andrade Victor
- Andreassen Ole A.
- Andreoni Simona
- Antequera Martirio
- Antikainen Riitta
- Antonell Anna
- Anttonen Vuokko
- AntĂșnez Carmen
- Aparicio Hugo J.
- Apostolova Liana G.
- Appollonio Ildebrando
- Arcaro Marina
- Archetti Silvana
- Armstrong Nicola
- Armstrong Nicola J.
- Arnold Steven E.
- Arosio Beatrice
- Arvas Mikko
- Assogna Francesca
- Asthana Sanjay
- Athanasiu Lavinia
- Atwood Craig S.
- Auge Franck
- Auranen Annika
- Auvinen PĂ€ivi
- Awaisa Ghazal
- Ayres Gayle
- Bacha Juan Ignacio
- Bahadori Maryam
- Bahrami Shahram
- Bailly Henri
- Baldwin Clinton T.
- Banaj Nerisa
- Baquero Miquel
- Barber Robert C.
- Barnes Lisa L.
- Barral Sandra
- Barral Sandra
- Bass Nicholas J.
- Bass Nick
- Bastiani Patrizia
- Bayer Anthony
- Beach Thomas G.
- Becker James T.
- Becker James T.
- Becker Tim
- Beecham Gary W.
- Beekly Duane
- Behrens Tim
- Beiser Alexa
- Belezhanska Diyana
- Bellenguez CĂ©line
- Below Jennifer E.
- Below Jennifer E.
- Ben-Shlomo Yoav
- Benchek Penelope
- Benchek Penelope
- Benitez Bruno A.
- Bennett David
- Benussi Alberto
- Benussi Luisa
- Bergh Sverre
- Bernardo-Harrington Mateus
- Berr Claudine
- Bertelson John
- Besse CĂ©line
- Bessi Valentina
- Betts Jo
- Bhangale Tushar
- Biessels Geert Jan
- Binetti Giuliano
- Bing Nan
- Bird Thomas D.
- Bis Joshua C.
- Biswas Shameek
- Bizarro Alessandra
- Bjerke Maria
- Blacker Deborah
- Blesa Rafael
- Blomster Timo
- Boada MercĂš
- Boecker Henning
- Boerwinkle Eric
- Boeve Bradley F.
- Boland Anne
- Borroni Barbara
- Boschi Silvia
- Bosnes Ingunn
- BossĂč Paola
- Bowen James D.
- Bowers Natalie
- Boxer Adam
- Brauer Matt
- Brayne Carol
- Brein Georg
- Bresner Catherine
- Bressler Jan
- Breteler Monique
- Brewer James
- Brice Alexis
- Brodaty Henry
- Broeckhoven Christine Van
- Bronson Paola
- Brookes KJ
- Brown Kristelle
- Brown Kristelle S.
- Brusco Luis Ignacio
- BrÄthen Geir
- Buendia Mar
- Buiza-Rueda Dolores
- Bullido MarĂa J.
- Burguera Juan Andrés
- Burholt Vanessa
- Burke James R.
- Burns Jeffrey M.
- Bush Will S.
- Bush William S.
- Buxbaum Joseph D.
- Bûrger Katharina
- Cairns Nigel J.
- Calero Miguel
- Caliskan Minal
- Call Katherine
- Call Kathy
- campion Dominique
- Campos-Martin Rafael
- Cano Amanda
- Cantwell Laura B.
- Cao Chuanhai
- Carlson Christopher S.
- Carlsson Cynthia M.
- Carney Regina M.
- Carpén Olli
- Carracedo Ăngel
- Carrasquillo Minerva M.
- Carrillo F.
- Carrillo FĂĄtima
- Carrion-Claro M.
- CarriĂłn-Claro Mario
- Casajeros MarĂa JosĂ©
- Castaño Eduardo M.
- Cañabate Pilar
- Cañabate Pilar
- Cecchetti Roberta
- Cervera-Carles Laura
- Challis Ben
- Chang Diana
- Chapuis Julien
- Charbonnier Camille
- Chasman Daniel
- Chasse Scott
- Chatelain Clement
- Chauhan Ganesh
- Chen Chia-Yen
- Chen Hao
- Chen Hubert
- Chen Hung-Hsin
- Chen Xing
- Chene GeneviĂšve
- Chesi Alessandra
- Chesselet Marie-Francoise
- Chhibber Aparna
- Chillotti Caterina
- Chin Nathaniel A.
- Chipi Elena
- Choy David
- Chu Audrey
- Chui Helena C.
- Chung Jaeyoon
- Chung Jaeyoon
- Ciccone Simona
- Ciullo Valentina
- Claassen Jurgen A. H. R.
- Clarimon Jordi
- Clark Christopher
- Clarke Robert
- Close David
- Collinge John
- Comic Hata
- Conti Elisa
- Cores Valeria
- Corma-GĂłmez AnaĂŻs
- Costa Marcos R.
- Costantini Emanuele
- Cox Simon
- Craft Suzanne
- Craig David
- Crane Paul K.
- Cribbs David H.
- Crocco Elizabeth A.
- Crohns Marika
- Cruchaga Carlos
- Cuccaro Michael L.
- Cuccaro Michael L.
- Cuesta Carolina
- Cullum Munro
- Cummings Beryl
- Cupples Adrienne L.
- Custodero Carlo
- Daian Delphine
- Dalmasso Maria Carolina
- Daly Mark
- Damotte Vincent
- Daniele Antonio
- Darby Eveleen
- Dardiotis Efthimios
- Dartigues Jean-François
- Davies Chloe
- Davies Gail
- Davis Barbara
- Davis Justin Wade
- de Deyn Peter Paul
- De Jager Philip L.
- de Mendonça Alexandre
- de Munain Adolfo Lopez
- de Paiva Lopes Katia
- de Rojas Itziar
- de Witte Lot D.
- Debette Stéphanie
- DeCarli Charles
- DeCarli Charles S.
- Deckert JĂŒrgen
- del Ser Teodoro
- Deleuze Jean-François
- della Briotta Parola Pietro
- della Briotta Parolo Pietro
- Deloukas Panagiotis
- Deloukas Pangiotis
- Denning Nicola
- Deramecourt Vincent
- Deramerourt Vincent
- DeStefano Anita
- DeToledo John
- Dichgans Martin
- Dick Malcolm
- Dickson Dennis W.
- Diego Susana
- Diehl-Schmid Janine
- Diez-Fairen MĂłnica
- Diogo Dorothee
- Djurovic Srdjan
- Dombroski Beth A.
- Dongen Jasper Van
- Donner Kati
- Doody Rachelle S.
- Dowzell Kimberley
- Drichel Dmitriy
- Duara Ranjan
- Dubois Bruno
- Dufouil Carole
- Duperron Marie-Gabrielle
- Dupuis Josée
- Duron Emmanuelle
- DĂŒzel Emrah
- Eaton Susan
- Ehm Meg
- Eicher John
- Eiriksdottir Gudny
- Eklund Kari
- Elenius Klaus
- Elliott Amanda
- Engelborghs Sebastiaan
- Epelbaum Jacques
- Ertekin-Taner NilĂŒfer
- Escott-Price Valentina
- Escuela R.
- Escuela RocĂo
- Esmaeeli Sahar
- Espinosa Ana
- Espinosa Miguel Angel Labrador
- Etchepareborda Ignacio
- Evans Denis A.
- Evans Tavia
- Ewers Michael
- Faber Kelley M.
- Fabrizio Tagliavini
- Fairchild Thomas J.
- Fallon Kenneth B.
- Fan Frank
- Fardo David W.
- Farlow Martin R.
- Farotti Lucia
- Farrell John J.
- Farrer Lindsay A.
- Fenoglio Chiara
- Fernandez-Hernandez Victoria
- FernĂĄndez-Fuertes Marta
- Ferrarese Carlo
- Ferrari Raffaele
- Ferreira Catarina B.
- Ferri Evelyn
- Ferris Steven
- Feulner Thomas
- Fievet Nathalie
- Fin Bertrand
- Fischer Peter
- Fisher Elizabeth
- Fitzpatrick Annette
- Fladby Tormod
- FlieĂbach Klaus
- Fohner Alison E.
- Fongang Bernard
- Fornage Myriam
- Foroud Tatiana M.
- Forsell Charlotte
- Fortea Juan
- Fostinelli Silvia
- Fox Caroline
- Fox Nick
- Fox Nick C.
- Franco-MacĂas Emlio
- Frank-GarcĂa Ana
- Frikke-Schmidt Ruth
- Froelich Lutz
- Frosch Matthew P.
- Frölich Lutz
- Fulton-Howard Brian
- Fulton-Howard Brian
- FÀrkkilÀ Martti
- Gailhajenet Anna
- Galasko Douglas R.
- Galeano Pablo
- Galimberti Daniela
- Gamboa Adriana
- Ganguli Mary
- Ganna Andrea
- Garcia-Gonzalez Pablo
- Garcia-Madrona Sebastian
- Garcia-Ribas Guillermo
- Garcia-Tabuenca Javier
- GarcĂa-Alberca Jose Maria
- GarcĂa-GonzĂĄlez Pablo
- Garrote-Espina L.
- Garrote-Espina Lorena
- Gearing Marla
- Geerlings Mirjam
- Georgantas Bob
- George-Hyslop Peter St
- Germani Sandra
- Gerrish Amy
- Geschwind Daniel H.
- Ghanbari Mohsen
- Ghetti Bernardino
- Ghidoni Roberta
- Ghosh Soumitra
- Giedraitis Vilmantas
- Giegling Ina
- Gilbert John R.
- Gill Michael
- Giorgio Giaccone
- Glatt Stephen J.
- Goate Alison M.
- Goldhardt Oliver
- Gomez-Fonseca Duber
- Gonzalez Hector M.
- GonzĂĄlez-PĂ©rez Antonio
- Gordillo Jorge Esparza
- Gormley Padhraig
- Goss Monica
- Gossel Matthias
- Grabe Hans
- Grabowski Thomas J.
- Gracia-Tabuenca Javier
- Graff Caroline
- Graff-Radford Neill R.
- Graham Robert
- Grand Quentin Le
- Grande Giulia
- Grant Struan F. A.
- Green Emma
- Green Robert C.
- Greenberg Steven
- Grenier-Boley Benjamin
- Grimmer Timo
- Growdon John H.
- Grunin Michelle
- GrĂŒnblatt Edna
- Gu Wei
- Gudnason Vilmundur
- Guerreiro Rita
- Guetta-Baranes Tamar
- Guitart Marina
- Gurling Hugh
- Gursoy Ulvi
- Gwilliam Rhian
- GĂłmez-Garre P.
- GĂłmez-Garre Pilar
- Haapasalo Annakaisa
- Habes Mohamad
- Hadjigeorgiou Georgios
- Haines Jonathan L.
- Haines Jonathan L.
- Hakonarson Hakon
- Hall James
- Hamilton Ronald L.
- Hamilton-Nelson Kara L.
- Hampel Harald
- Hannequin Didier
- Hannula-Jouppi Katariina
- Hanon Olivier
- Harari Oscar
- Hardy John
- Harju Jarmo
- Harju Terttu
- Harold Denise
- Harrell Lindy E.
- Hartmann Annette M.
- Harvima Ilkka
- Harwood Janet
- Hausner Lucrezia
- Haut Jacob
- Hautala Nina
- Havulinna Aki
- Head Elizabeth
- Heap Graham
- Heckbert Susan R.
- Hedman Ă sa
- Heikkinen Sami
- Heilmann-Heimbach Stefanie
- Helisalmi Seppo
- Henderson Victor W.
- Hendolin Minna
- Heneka Michael T.
- Hernandez Michelle
- HernĂĄndez Isabel
- Herold Christine
- Heron Samuel
- Herrmann Martin J.
- Heun Reinhard
- Heuser Isabella
- Hevilla Saray
- Heyne Henrike
- Hiekkalinna Tero
- Hiltunen Mikko
- Hinttala Reetta
- Hochfeld Marla
- Hodges Angela
- Hofer Edith
- Hoffman Joshua
- Hoffmann Per
- Hohman Timothy
- Hollingworth Paul
- Holmans Peter A.
- Holmes Clive
- Holstege Henne
- Holzinger Emily
- Hong Elliot
- Honig Lawrence S.
- Hooper Nigel M.
- Hort Jakub
- Hu Xinli
- Huang Yunfeng
- Huebinger Ryan M.
- Huentelman Matthew J.
- Hughes Timothy
- Huhtakangas Johanna
- Huilaja Laura
- Hulette Christine M.
- Hulsman Marc
- Humphrey Jack
- Hunkapiller Julie
- Hyman Bradley T.
- Hynan Linda S.
- HyvÀrinen Kati
- HĂŒll Michael
- Ibanez Laura
- Ibarria Marta
- Ikram M. Arfan
- Ingelsson Martin
- Ingino Carlos
- Iriarte Maite Mendioroz
- IsomÀki Pia
- Jacob Howard
- Jalanko Anu
- Jambulingam Dhanaprakash
- Janowitz Daniel
- Jansen Iris E.
- Jarvik Gail P.
- Jayadev Suman
- Jessen Frank
- JesĂșs S.
- JesĂșs Silvia
- Jian Xueqiu
- Jiménez Manuel Gonzålez
- Jin Lee-Way
- Joensuu Heikki
- Johansson Charlotte
- John Sally
- Johnson Kim
- Johnson Leigh
- Johnston Janet A.
- Johnston Jarret A.
- Jones Lesley
- Juan Pascual SĂĄnchez
- Julkunen Valtteri
- Jun Gyungah R.
- Junttila Juhani
- Juonala Markus
- Jussila Airi
- JĂ€rvensivu Elina
- Jöckel Karl-Heinz
- Kaarniranta Kai
- Kaarteenaho Riitta
- Kaiharju Essi
- Kaipiainen-SeppÀnen Oili
- Kajanne Risto
- Kalaoja Marita
- Kalpala Kirsi
- Kamboh M. Ilyas
- Kanai Masahiro
- Kangasniemi Eeva
- Kankaanranta Hannu
- Kaprio Jaakko
- Karihtala Peeter
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- Niiranen Teemu
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- Palta Priit
- Pancho Ana
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- Papenberg Goran
- Parisi Joseph E.
- Parkkinen Jaakko
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- Partanen Jukka
- Parveen Kayenat
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- Passmore Peter
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- Pastor Alfonso Arias
- Pastor Ana Belén
- Pastor Pau
- Patel Yash
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- Paulson Henry L.
- Paus Tomas
- Pausova Zdenka
- Pavlik Valory
- Paydarfar David
- PelejĂ Esther
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- Pelkonen Margit
- Peloso Gina
- Peltola Jukka
- Peltonen Markku
- Peltonen Sirkku
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- Piras Fabrizio
- Piras Federica
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- Pisanu Claudia
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- Plenge Robert
- Podgornaia Anna
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- Politis Daniel G.
- Polk Marsha
- Poon Wayne W.
- Popovic Relja
- Popp Julius
- Posthuma Danielle
- Potter Huntington
- Powell John
- Powell John F.
- Preckler Silvia
- Prestia Federico Ariel
- Priller Josef
- Proitsi Petra
- Prokic Ivana
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- Puerta Raquel
- Pulford David
- Pulkki Kari
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- PylkÀs Katri
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- PĂ©rez-CordĂłn Alba
- PĂ©rez-Tur Jordi
- Qu Liming
- Quarless Danjuma
- Quenez Olivier
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- Quintela Inés
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- Raikkonen-Talvitie Katri
- Rainero Innocenzo
- Raj Ashok
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- Ramakers Inez
- Ramirez Alfredo
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- van der Flier Wiesje M.
- van der Lee Sven J.
- van der Lugt Aad
- van Duijn Cornelia M.
- van Eldik Linda J.
- van Lent Debora Melo
- van Rooij Jeroen
- van Swieten John
- Vance Jeffery
- Vandenberghe Rik
- Vardarajan Badri N.
- Vardy Emma
- Vargas Liliana
- Vassar Robert
- Verhey Frans
- Vicente Maria Pilar
- Vidal Jean-SĂ©bastien
- Vigo-Ortega R.
- Vigo-Ortega Rosario
- Vilas Raquel Huerto
- Vinters Harry V.
- Virolainen Petri
- Vivancos Liliana
- Vogelgsang Jonathan
- Vojinovic Dina
- Vonsattel Jean-Paul
- Voutilainen Markku
- Vyhnalek Martin
- Wadhawan Samir
- Wagner Michael
- Wallon David
- Wang Clarence
- Wang Li-San
- Wang Ruiqi
- Wang Yanbing
- Warden Donald
- Waring Jeff
- Waring Jeffrey
- Warner Nick
- Warren Jason D.
- Waterworth Dawn
- Weber Heike
- Weinhold Leonie
- Weinstein Galit
- Weintraub Sandra
- Welsh-Bohmer Kathleen A.
- Whelan Christopher
- Whitehead Patrice L.
- Wichmann H-Erich
- Wigmore Eleonor
- Wijsman Ellen M.
- Wilcock Gordon
- Wilhelmsen Kirk C.
- Williams Amy
- Williams Benjamin
- Williams Dylan
- Williams Julie
- Williamson Jennifer
- Wilms Henrik
- Wiltfang Jens
- Windle Gill
- Wingo Thomas S.
- Wisniewski Thomas
- Wittfeld Katharina
- Woltjer Randall L.
- Wong Regis
- Woods Bob
- Woon Martin
- Wright Clinton B.
- Wu Chuang-Kuo
- Wu Ying
- Xia Tai-he
- Xu Ethan
- Xu Fanli
- Yanek Lisa
- Yang Qiong
- Yang Yunju
- Yannakoulia Mary
- Yaqub Amber
- Younkin Steven G.
- Yu Chang-En
- Yu Lei
- Zare Habil
- Zhang Xiaoling
- Zhang Yuanchao
- Zhao Yi
- Zhao Yi
- Zhou Wei
- Zhu Congcong
- Zhu Xiongwei
- Ziemann Adam
- Zoia Chiara Paola
- Zompo Maria Del
- Zulaica Miren
- Ălvarez Victoria
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/04/2022
- Field of study
Characterization of the genetic landscape of Alzheimerâs disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage genome-wide association study totaling 111,326 clinically diagnosed/âproxyâ AD cases and 677,663 controls. We found 75 risk loci, of which 42 were new at the time of analysis. Pathway enrichment analyses confirmed the involvement of amyloid/tau pathways and highlighted microglia implication. Gene prioritization in the new loci identified 31 genes that were suggestive of new genetically associated processes, including the tumor necrosis factor alpha pathway through the linear ubiquitin chain assembly complex. We also built a new genetic risk score associated with the risk of future AD/dementia or progression from mild cognitive impairment to AD/dementia. The improvement in prediction led to a 1.6- to 1.9-fold increase in AD risk from the lowest to the highest decile, in addition to effects of age and the APOE Δ4 allele