Efecto de la ingesta de café sobre la frecuencia crítica de fusión en una muestra de estudiantes universitarios

RESUMEN INTRODUCCIÓN Y OBJETIVOS: La frecuencia crítica de fusión (FCF) ha sido ampliamente utilizada como un indicador de nivel de alertamiento en estudios psicofarmacológicos y como ayuda diagnóstica en enfermedades neurológicas. El presente trabajo utilizó un prototipo electrónico para evaluar el efecto de la ingesta de una dosis social de café, sobre la FCF en estudiantes voluntarios de la facultad de salud de la Universidad Industrial de Santander.  MATERIALES Y MÉTODOS: Se incluyeron 13 hombres y 13 mujeres bajo un diseño seudo-experimental donde a los participantes se les evaluó (pre y post ingesta de café) la FCF por los métodos ascendente y descendente. La dosis de café estuvo entre 2,5 y 2,8 gramos de un producto comercial disponible en tiendas de mercado de la ciudad, que decía contener entre el 3,9 y 4,4% de cafeína en el producto seco.  RESULTADOS: Los principales resultados mostraron que el grupo de hombres tuvo mayores valores de la FCF "basales" que las mujeres, mientras que la ingesta de café produjo un incremento de la FCF en las mujeres y no en los hombres. Modelos basados en regresiones múltiples, demostraron que tanto el género como la hora de la evaluación, contribuyeron a la explicación del efecto producido por la ingesta de café.  CONCLUSIONES Y RECOMENDACIONES: El protocolo y la herramienta implementados, permitieron detectar el aumento de la FCF (incremento del alertamiento) inducido por la cafeína, que adicionalmente estuvo asociado al género y al horario de evaluación de los participantes. Se recomienda su implementación para la evaluación de los efectos de otros psicofármacos. Salud UIS 2009; 41: 41-48 Palabras clave: Frecuencia crítica de fusión, cafeína, psicofármacos, alertamiento ABSTRACT   INTRODUCTION AND OBJECTIVES: The Critical ficker fusión frequency (CFF) has been widely used as an arousal level indicator in psychopharmacological studies and as diagnostic aid in neurological disease. The current work used an electronic prototype to evaluate the effect of one social dose of coffee, on the CFF in volunteer students of the Medical School in the Universidad Industrial de Santander.MATERIALS AND METHODS: Were included 13 men and 13 women in a pseudo-experimental study, in each participant was evaluated (pre and post coffee intake) the CFF by ascending and descending methods|. The dose of coffee was between 2.5 and 2.8 grams of a commercial product available in commercial shops in the city. It stated to contains between 3.9 and 4.4% caffeines of dry product. RESULTS: The principal results showed the male group, had higher valúes of "basal" CFF than the female group, while the coffee intake produced an increase of CFF into the woman group but do not into the male group. Models based inmúltiple regression, demonstrated that as gender as the evaluation hour, contribute to the explication of the coffee intake effect.  CONCLUSIONS AND RECOMMENDATIONS: The protocol and the tool used; permitted detection of an increase of the CFF (increase of arousal) induced by caffeine, which was additionally, associated to gender and evaluation hour of participants. It's recommended to evaluate the effects of other psychotropic drugs. Salud UIS 2009; 41: 41-48 Keywords: Critical Flicker Fusión Frequency, Caffeine, psychotropic drugs, arousa

Efecto de la ingesta de café sobre la frecuencia crítica de fusión en una muestra de estudiantes universitarios

RESUMEN INTRODUCCIÓN Y OBJETIVOS: La frecuencia crítica de fusión (FCF) ha sido ampliamente utilizada como un indicador de nivel de alertamiento en estudios psicofarmacológicos y como ayuda diagnóstica en enfermedades neurológicas. El presente trabajo utilizó un prototipo electrónico para evaluar el efecto de la ingesta de una dosis social de café, sobre la FCF en estudiantes voluntarios de la facultad de salud de la Universidad Industrial de Santander.  MATERIALES Y MÉTODOS: Se incluyeron 13 hombres y 13 mujeres bajo un diseño seudo-experimental donde a los participantes se les evaluó (pre y post ingesta de café) la FCF por los métodos ascendente y descendente. La dosis de café estuvo entre 2,5 y 2,8 gramos de un producto comercial disponible en tiendas de mercado de la ciudad, que decía contener entre el 3,9 y 4,4% de cafeína en el producto seco.  RESULTADOS: Los principales resultados mostraron que el grupo de hombres tuvo mayores valores de la FCF "basales" que las mujeres, mientras que la ingesta de café produjo un incremento de la FCF en las mujeres y no en los hombres. Modelos basados en regresiones múltiples, demostraron que tanto el género como la hora de la evaluación, contribuyeron a la explicación del efecto producido por la ingesta de café.  CONCLUSIONES Y RECOMENDACIONES: El protocolo y la herramienta implementados, permitieron detectar el aumento de la FCF (incremento del alertamiento) inducido por la cafeína, que adicionalmente estuvo asociado al género y al horario de evaluación de los participantes. Se recomienda su implementación para la evaluación de los efectos de otros psicofármacos. Salud UIS 2009; 41: 41-48 Palabras clave: Frecuencia crítica de fusión, cafeína, psicofármacos, alertamiento ABSTRACT   INTRODUCTION AND OBJECTIVES: The Critical ficker fusión frequency (CFF) has been widely used as an arousal level indicator in psychopharmacological studies and as diagnostic aid in neurological disease. The current work used an electronic prototype to evaluate the effect of one social dose of coffee, on the CFF in volunteer students of the Medical School in the Universidad Industrial de Santander.MATERIALS AND METHODS: Were included 13 men and 13 women in a pseudo-experimental study, in each participant was evaluated (pre and post coffee intake) the CFF by ascending and descending methods|. The dose of coffee was between 2.5 and 2.8 grams of a commercial product available in commercial shops in the city. It stated to contains between 3.9 and 4.4% caffeines of dry product. RESULTS: The principal results showed the male group, had higher valúes of "basal" CFF than the female group, while the coffee intake produced an increase of CFF into the woman group but do not into the male group. Models based inmúltiple regression, demonstrated that as gender as the evaluation hour, contribute to the explication of the coffee intake effect.  CONCLUSIONS AND RECOMMENDATIONS: The protocol and the tool used; permitted detection of an increase of the CFF (increase of arousal) induced by caffeine, which was additionally, associated to gender and evaluation hour of participants. It's recommended to evaluate the effects of other psychotropic drugs. Salud UIS 2009; 41: 41-48 Keywords: Critical Flicker Fusión Frequency, Caffeine, psychotropic drugs, arousa

Psychometric Properties of the Diener Satisfaction With Life Scale With Five Response Options Applied to the Colombian Population

Introduction: The Satisfaction with Life Scale (SWLS), developed by Diener, Emmons, Larsen, and Griffin in 1985, comprises five items with seven response options in terms of agreement-disagreement. Recently, there has been a suggestion to reduce the response options of the SWLS to optimize its applicability in different cultural contexts. Objective: The study aims to assess the psychometric properties of the SWLS with five response options in the Colombian population. Specifically, we studied the dimensionality, invariance by gender and age (among a group of adolescents and emerging adults under 25 years and a group of adults of intermediate age and established adulthood under 59 years), convergent validity (with optimism), and divergent (with pessimism) and concurrent validity with other measures of well-being (flourishing, positive, and negative affects). Methodology: This project was a cross-sectional study using a non-probabilistic sample of the general population. Participants were included if they identified themselves as Colombian and were at least 18 years of age. The final sample comprised 1,255 participants. The average age was 25.62 years (SD = 8.60) ranging from 18 to 67 years of age, and 35.8% of the participants were men. In addition to SWLS, we used the Flourishing Scale (FS), Life Orientation Test-Revised (LOT-R), and Scale of Positive and Negative Experience (SPANE). Results: Cronbach's alpha coefficient (0.842), composite reliability (0.851), and average variance extracted (0.537) showed very good values. CFA was conducted to test the one-dimensional structure of FS, showing excellent goodness of fit [χ2(5) = 15.774, p < 0.001, CFI = 0.992, TLI = 0.985, RMSEA = 0.042, 90% RMSEA CI (0.020, 0.066), and SRMR = 0.016]. The correlations calculated among life satisfaction (SWLS) with flourishing (FS), positive and negative affects (SPANE), optimism, and pessimism (LOT-R) were statistically significant and as expected. Configural, metric, and scalar invariance across gender and age were confirmed. Percentiles were provided for the total score and for age. Conclusions: The SWLS with five response options has adequate psychometric properties in the Colombian population, and the use of this version (with 5 response options) is recommended due to its greater applicability

La investigación universitaria sobre educación : dilemas y prácticas

Se presentan los resultados de investigaciones realizadas en un contexto institucional: la Facultad de Educación Elemental y Especial (FEEYE), de la Universidad Nacional de Cuyo durante el bienio 2011-2013 y son resultado de los proyectos subsidiados por la Secretaría de Ciencia, Técnica y Posgrado de la misma Universidad a partir del programa de incentivo a docentes investigadores o subsidiados por la unidad académica

Examining the immune signatures of SARS-CoV-2 infection in pregnancy and the impact on neurodevelopment: Protocol of the SIGNATURE longitudinal study.

The COVID-19 pandemic represents a valuable opportunity to carry out cohort studies that allow us to advance our knowledge on pathophysiological mechanisms of neuropsychiatric diseases. One of these opportunities is the study of the relationships between inflammation, brain development and an increased risk of suffering neuropsychiatric disorders. Based on the hypothesis that neuroinflammation during early stages of life is associated with neurodevelopmental disorders and confers a greater risk of developing neuropsychiatric disorders, we propose a cohort study of SARS-CoV-2-infected pregnant women and their newborns. The main objective of SIGNATURE project is to explore how the presence of prenatal SARS-CoV-2 infection and other non-infectious stressors generates an abnormal inflammatory activity in the newborn. The cohort of women during the COVID-19 pandemic will be psychological and biological monitored during their pregnancy, delivery, childbirth and postpartum. The biological information of the umbilical cord (foetus blood) and peripheral blood from the mother will be obtained after childbirth. These samples and the clinical characterisation of the cohort of mothers and newborns, are tremendously valuable at this time. This is a protocol report and no analyses have been conducted yet, being currently at, our study is in the recruitment process step. At the time of this publication, we have identified 1,060 SARS-CoV-2 infected mothers and all have already given birth. From the total of identified mothers, we have recruited 537 SARS-COV-2 infected women and all of them have completed the mental health assessment during pregnancy. We have collected biological samples from 119 mothers and babies. Additionally, we have recruited 390 non-infected pregnant women

Garantía de calidad de los servicios de mamografía: Normas básicas para América Latina y el Caribe

Fil: Barr, Helen. No especifíca;Fil: Blanco, Susana Alicia Ana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Ministerio de Salud. Instituto Nacional del Cáncer; ArgentinaFil: Albarracín, Virginia Helena. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Priscilla, Butler. No especifíca;Fil: da Paz, María Angela. No especifíca;Fil: Fleitas, Ileana. No especifíca;Fil: Jiménez, Pablo. No especifíca;Fil: Luciani, Silvana. No especifíca;Fil: Manrique, Javier. No especifíca;Fil: Mazal, Jonathan. No especifíca;Fil: Medlen, Kayiba. No especifíca;Fil: Miller, Collie. No especifíca;Fil: Mora, Patricia. No especifíca;Fil: Valdez Moreno, Martha Elena. No especifíca;Fil: Mosodeen, Murrie. No especifíca;Fil: Mysler, Gustavo. No especifíca;Fil: Nusche Berenguer, Bernardo. No especifíca;Fil: Pastel, Mary. No especifíca;Fil: Pinochet, Miguel. No especifíca;Fil: Ruiz Trejo, Cesar. No especifíca;Fil: Sisney, Gale. No especifíca;Fil: Saraiya, Mona. No especifíca;Fil: Solis, Esteban. No especifíca;Fil: Swann, Phillip. No especifíca

Examining the immune signatures of SARS-CoV-2 infection in pregnancy and the impact on neurodevelopment: Protocol of the SIGNATURE longitudinal study

The COVID-19 pandemic represents a valuable opportunity to carry out cohort studies that allow us to advance our knowledge on pathophysiological mechanisms of neuropsychiatric diseases. One of these opportunities is the study of the relationships between inflammation, brain development and an increased risk of suffering neuropsychiatric disorders. Based on the hypothesis that neuroinflammation during early stages of life is associated with neurodevelopmental disorders and confers a greater risk of developing neuropsychiatric disorders, we propose a cohort study of SARS-CoV-2-infected pregnant women and their newborns. The main objective of SIGNATURE project is to explore how the presence of prenatal SARS-CoV-2 infection and other non-infectious stressors generates an abnormal inflammatory activity in the newborn. The cohort of women during the COVID-19 pandemic will be psychological and biological monitored during their pregnancy, delivery, childbirth and postpartum. The biological information of the umbilical cord (foetus blood) and peripheral blood from the mother will be obtained after childbirth. These samples and the clinical characterisation of the cohort of mothers and newborns, are tremendously valuable at this time. This is a protocol report and no analyses have been conducted yet, being currently at, our study is in the recruitment process step. At the time of this publication, we have identified 1,060 SARS-CoV-2 infected mothers and all have already given birth. From the total of identified mothers, we have recruited 537 SARS-COV-2 infected women and all of them have completed the mental health assessment during pregnancy. We have collected biological samples from 119 mothers and babies. Additionally, we have recruited 390 non-infected pregnant women.This work has received support from the Fundación Alicia Koplowitz to realize the epigenetic wide association study and to the clinical assessment to the children. This work has also received public support from the Consejería de Salud y Familias para la financiación de la investigación, desarrollo e innovación (i + d + i) biomédica y en ciencias de la salud en Andalucía (CSyF 2021 - FEDER). Grant Grant number PECOVID- 0195-2020. Convocatoria financiada con Fondo Europeo de Desarrollo Regional (FEDER) al 80% dentro del Programa Operativo de Andalucía FEDER 2014-2020. Andalucía se mueve con Europa. NG-T received payment under Rio Hortega contract CM20-00015 with the Carlos III Health Institute.Peer reviewe

WOMEN FORCE: A STUDY UPON RESILIENCE STRATEGIES AND TRANSFORMATION IN THE HUMAN OCCUPATION OF WOMEN AS VICTIMS OF COLOMBIAN ARMED CONFLICT.

La presente investigación tiene por objetivo evidenciar la identificación de las estrategias de resiliencia frente a la transformación de la ocupación humana de mujeres víctimas de desplazamiento en el marco del conflicto armado Colombiano, para lo cual se plantea una justificación del problema de investigación, centrado principalmente en la fuerza que tienen las mujeres y la capacidad de agenciamiento posterior a situaciones de adversidad; seguidamente se aclara en términos conceptuales lo que para la investigación se entiende por resiliencia, ocupación humana, cuerpo y conflicto armado, hechos victimizantes diferenciados hacia las mujeres y sus consecuencias en relación a la transformación en las actividades significativas. Finalmente y a la luz de lo evidenciado en el marco teórico y el estado del arte, se propone realizar la indagación a partir de un diseño de investigación de tipo fenomenológico (cualitativo) y descriptivo en una muestra de 4 mujeres mayores de 18 años y víctimas del conflicto armado por hechos victimizantes de desplazamiento; adicionalmente se da a conocer un abordaje a través de lenguajes corporales para la identificación de las estrategias de resiliencia mediante elementos de danza que para este caso se mencionan: (Danza Orgánica, Danza Butoh y Danza Contacto). Se identifica a partir del abordaje de indagación que las principales estrategias de resiliencia frente a la transformación de la ocupación humana en mujeres víctimas de desplazamiento en el marco del conflicto armado en Colombia están relacionadas con el hacer por los otros en forma de deber cumplido frente a los roles maternos, desde la retroalimentación afectiva; el autoconocimiento y autogestión en el restablecimiento de sus proyectos de vida, que se fortalecen desde el reconocimiento de capacidades, habilidades y recursos propios; y finalmente la espiritualidad desde la conciencia de sus fortalezas para hacer frente al día a día.The objective of the research is to give evidence upon resilience strategies identified in the lives of Colombian female victims who faced a transformation in their human occupation after suffering forced displacement from their homelands in the framework of the armed-civil conflict of the country. For which, the research problem is justified in the premise bellow: Colombian female victims have develop an ability to face post- conflict situations. This justification is followed by the explanation of research concepts as resilience; human occupation; body versus war-armed conflict; oppressing facts upon women and its consequences, which concludes as a transformation into meaningful activities. Moreover, based in what is supported in the theoretical framework and the state of art, the research was projected from a phenomenological- descriptive method (qualitative). The participants were four adult women who are victims of forced land displacement. In addition, body language (dance) was the approach to identify the resilience strategies; the dance elements taken into account were (Organic Dance, Butoh Dance and Contact Improvisation). As a conclusion, from the approach, it was identified that, the main resilience strategies facing the human occupation in women victims of Colombian armed-conflict are related to “doing for others” as an accomplishment to the maternal role based in affective feedback; self-awareness and their own management to restore their life-projects. Which in turn is reinforced by their own recognition of skills and resources and finally, the spirituality from the cognizance of their strengths to face their everyday

Extruded whole grain diets based on brown, soaked and germinated rice: Effects on cecum health, ca absorption and bone parameters of growing wistar rats. Part I

The influence of diets with whole rice processed ingredients on cecum health, calcium absorption and bone parameters was studied using an animal model. Thirty-two male Wistar rats were fed with Control (C), extruded Brown rice (B), extruded Soaked whole rice (S) and extruded Germinated whole rice (G) diets for 60 days. The cecum weight, cecal content pH, cecal sIgA content, and β-glucosidase and β-glucuronidase activities were determined. Calcium apparent absorption, total bone mineral content and density and right femur parameters (ashes, organic content, calcium and P) were evaluated. The results showed that animals fed with whole grain diets have lower food intake in comparison with the C diet, and decreased cecal content pH (7.06 vs. 6.33) and β-glucosidase activity (1.66 vs. 0.21 μmol p-nitrophenol g-1 cc h-1). Even though calcium apparent absorption was not different among treatments (∼70%), none of the whole grain diets improved calcium related bone parameters over the control fed rats (cellulose as dietary fibre).Fil: Albarracín, Micaela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Instituto de Tecnología de los Alimentos; ArgentinaFil: Weisstaub, Adriana Ruth. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; ArgentinaFil: Zuleta, Angela. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; ArgentinaFil: Drago, Silvina Rosa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Instituto de Tecnología de los Alimentos; Argentin