4,002 research outputs found
Trans-nasal endoscopic and intra-oral combined approach for odontogenic cysts
Maxillary cysts are a common finding in maxillofacial surgery, dentistry and otolaryngology. Treatment is surgical; a traditional approach includes Caldwell-Luc and other intra-oral approaches. In this article, we analyse the outcomes of 9 patients operated on using a combined intra-oral and trans-nasal approach to the aforementioned disease. Although the number of patients is small, the good results of this study suggest that the combined approach might be a reliable treatment option
Developments in European Product Liability
The eight questions discussed in this article are as follows: (1) Why is new legislation needed in the field of product liability? (2) What should be the basis of a new regime of product liability? (3) Who should be liable? (4) What products should be subject to a new regime of product liability? (5) Who should be entitled to sue? (6) What defenses shall be allowed? (7) What damage should be compensated? (8) How long should the producer\u27s liability last
Analysis of the effects of an oncogenic stress on the cell cycle in human tumoral cells
Although differing only for the last 24 aminoacids, the three major isoforms of p21 Ras (Ha-, Ki- and N \u2013Ras) can trigger alternative pathways of signal transduction, at least in part as a consequence of different post-translational modifications and subcellular localization. Ras mutations are a common event in tumorigenesis. In colorectal carcinomas (CRCs) the mutations affect almost exclusively Ki-Ras, while Ha-Ras mutations are mostly found in bladder carcinomas and N-Ras mutations in leukemia cells. In almost all cases, the genetic alteration is a point mutation in codons 12 or 13, and less frequently in codon 61. By affecting the GTPase activity of the protein, they always lead to a constitutively active protein. However, data obtained in different experimental systems or by analysis of primary and metastatic tumors show that not only mutations of different isoforms of Ras, but also mutations in different codons or different mutations in the same codon of the same isoform of Ras may have diverse biological consequences. To shed more light on the molecular mechanisms responsible for the different effects of Ras mutations, we have obtained stable clones of HT-29 (a human colorectal adenocarcinoma cell line in which the endogenous Ras genes are wild type) transfected with cDNAs codifying Ha-RasG12V, Ki-RasG12V and Ki-RasG13D, under the control of an hormone-inducible promoter. We found that the expression of each of these mutated Ras isoforms induces specific, different effects on cell morphology and growth rate. FACS analysis shows also a differential effect on the cell cycle. H-RasG12V expression, in addition, induces apoptosis, through caspase activation mediated by p53 independent, MEK-1 dependent expression of the CDK inhibitor p21
Adjoint bi-continuous semigroups and semigroups on the space of measures
For a given bi-continuous semigroup T on a Banach space X we define its
adjoint on an appropriate closed subspace X^o of the norm dual X'. Under some
abstract conditions this adjoint semigroup is again bi-continuous with respect
to the weak topology (X^o,X). An application is the following: For K a Polish
space we consider operator semigroups on the space C(K) of bounded, continuous
functions (endowed with the compact-open topology) and on the space M(K) of
bounded Baire measures (endowed with the weak*-topology). We show that
bi-continuous semigroups on M(K) are precisely those that are adjoints of a
bi-continuous semigroups on C(K). We also prove that the class of bi-continuous
semigroups on C(K) with respect to the compact-open topology coincides with the
class of equicontinuous semigroups with respect to the strict topology. In
general, if K is not Polish space this is not the case
On the continuous Cesà ro operator in certain function spaces
“The final publication is available at Springer via http://dx.doi.org/10.1007/s11117-014-0321-5"Various properties of the (continuous) Cesà ro operator C, acting on Banach
and Fréchet spaces of continuous functions and L p-spaces, are investigated. For
instance, the spectrum and point spectrum of C are completely determined and a
study of certain dynamics of C is undertaken (eg. hyper- and supercyclicity, chaotic
behaviour). In addition, the mean (and uniform mean) ergodic nature of C acting in
the various spaces is identified.The research of the first two authors was partially supported by the projects MTM2010-15200 and GVA Prometeo II/2013/013 (Spain). The second author gratefully acknowledges the support of the Alexander von Humboldt Foundation.Albanese, AA.; Bonet Solves, JA.; Ricker, WJ. (2015). On the continuous Cesà ro operator in certain function spaces. Positivity. 19:659-679. https://doi.org/10.1007/s11117-014-0321-5S65967919Albanese, A.A.: Primary products of Banach spaces. Arch. Math. 66, 397–405 (1996)Albanese, A.A.: On subspaces of the spaces L loc p and of their strong duals. Math. Nachr. 197, 5–18 (1999)Albanese, A.A., Moscatelli, V.B.: Complemented subspaces of sums and products of copies of L 1 [ 0 , 1 ] . Rev. Mat. Univ. Complut. Madr. 9, 275–287 (1996)Albanese, A.A., Bonet, J., Ricker, W.J.: Mean ergodic operators in Fréchet spaces. Ann. Acad. Sci. Fenn. Math. 34, 401–436 (2009)Albanese, A.A., Bonet, J., Ricker, W.J.: On mean ergodic operators. In: Curbera, G.P. (eds.) Vector Measures, Integration and Related Topics. Operator Theory: Advances and Applications, vol. 201, pp. 1–20. Birkhäuser, Basel (2010)Albanese, A.A., Bonet, J., Ricker, W.J.: C 0 -semigroups and mean ergodic operators in a class of Fréchet spaces. J. Math. Anal. Appl. 365, 142–157 (2010)Albanese, A.A., Bonet, J., Ricker, W.J.: Convergence of arithmetic means of operators in Fréchet spaces. J. Math. Anal. Appl. 401, 160–173 (2013)Bayart, F., Matheron, E.: Dynamics of linear operators. Cambridge Tracts in Mathematics, vol. 179. Cambridge University Press, Cambridge (2009)Bellenot, S.F., Dubinsky, E.: Fréchet spaces with nuclear Köthe quotients. Trans. Am. Math. Soc. 273, 579–594 (1982)Bonet, J., Frerick, L., Peris, A., Wengenroth, J.: Transitive and hypercyclic operators on locally convex spaces. Bull. Lond. Math. Soc. 37, 254–264 (2005)Boyd, D.W.: The spectrum of the Cesà ro operator. Acta Sci. Math. (Szeged) 29, 31–34 (1968)Brown, A., Halmos, P.R., Shields, A.L.: Cesà ro operators. Acta Sci. Math. (Szeged) 26, 125–137 (1965)Dierolf, S., Zarnadze, D.N.: A note on strictly regular Fréchet spaces. Arch. Math. 42, 549–556 (1984)Dunford, N., Schwartz, J.T.: Linear Operators I: General Theory (2nd Printing). Wiley-Interscience, New York (1964)Galaz Fontes, F., SolÃs, F.J.: Iterating the Cesà ro operators. Proc. Am. Math. Soc. 136, 2147–2153 (2008)Galaz Fontes, F., Ruiz-Aguilar, R.W.: Grados de ciclicidad de los operadores de Cesà ro–Hardy. Misc. Mat. 57, 103–117 (2013)González, M., León-Saavedra, F.: Cyclic behaviour of the Cesà ro operator on L 2 ( 0 , + ∞ ) . Proc. Am. Math. Soc. 137, 2049–2055 (2009)Grosse-Erdmann, K.G., Peris Manguillot, A.: Linear chaos. In: Universitext. Springer, London (2011)Hardy, G.H., Littlewood, J.E., Pólya, G.: Inequalities. In: Reprint of the 1952 Edition. Cambridge Mathematical Library. Cambridge University Press, Cambridge (1988)Krengel, U.: Ergodic theorems. In: De Gruyter Studies in Mathematics, vol. 6. Walter de Gruyter Co., Berlin (1985)Leibowitz, G.M.: Spectra of finite range Cesà ro operators. Acta Sci. Math. (Szeged) 35, 27–28 (1973)Leibowitz, G.M.: The Cesà ro operators and their generalizations: examples in infinite-dimensional linear analysis. Am. Math. Mon. 80, 654–661 (1973)León-Saavedra, F., Piqueras-Lerena, A., Seoane-Sepúlveda, J.B.: Orbits of Cesà ro type operators. Math. Nachr. 282, 764–773 (2009)Lin, M.: On the uniform ergodic theorem. Proc. Am. Math. Soc. 43, 337–340 (1974)Meise, R., Vogt, D.: Introduction to functional analysis. In: Oxford Graduate Texts in Mathematics, vol. 2. The Clarendon Press; Oxford University Press, New York (1997)Metafune, G., Moscatelli, V.B.: Quojections and prequojections. In: TerzioÄŸlu, T. (ed.) Advances in the Theory of Fréchet spaces. NATO ASI Series, vol. 287, pp. 235–254. Kluwer Academic Publishers, Dordrecht (1989)Moscatelli, V.B.: Fréchet spaces without norms and without bases. Bull. Lond. Math. Soc. 12, 63–66 (1980)Piszczek, K.: Quasi-reflexive Fréchet spaces and mean ergodicity. J. Math. Anal. Appl. 361, 224–233 (2010)Piszczek, K.: Barrelled spaces and mean ergodicity. Rev R. Acad. Cienc. Exactas Fis. Nat. Ser. A Math. RACSAM 104, 5–11 (2010)Yosida, K.: Functional Analysis, 6th edn. Springer, Berlin (1980
Un'applicazione della Social Network Analisys alla rete di relazioni di un Gruppo d’Acquisto Solidale: l’esperienza di Gasualmente
The phenomenon of GAS (Solidarity Purchase Groups) in Sicily has in Gasualmente an important actor. This GAS, was created following a structured training program and research by the Faculty of Agriculture of the University of Palermo. It now plays an important role as activator of relationships and ethical affirmation of critical consumption, and promotion of organic products. The study aims through the Social Network Analysis, to investigate Gasualmente network and the role played by all the actors involved
The Divertor Tokamak Test facility proposal: Physical requirements and reference design
The main goal of the Divertor Tokamak Test facility (DTT) is to explore alternative power exhaust solutions for DEMO. The principal objective is to mitigate the risk of a difficult extrapolation to fusion reactor of the conventional divertor based on detached conditions under test on ITER. The task includes several issues, as: (i) demonstrating a heat exhaust system capable of withstanding the large load of DEMO in case of inadequate radiated power fraction; (ii) closing the gaps in the exhaust area that cannot be addressed by present devices; (iii) demonstrating how the possible implemented solutions (e.g., advanced divertor configurations or liquid metals) can be integrated in a DEMO device. In view of these goals, the basic physical DTT parameters have been selected according to the following guidelines: (i) edge conditions as close as possible to DEMO in terms of dimensionless parameters; (ii) flexibility to test a wide set of divertor concepts and techniques; (iii) compatibility with bulk plasma performance; (iv) an upper bound of 500 M€ for the investment costs. © 2017 The Author
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