Computing New Optimized Routes for GPS Navigators Using Evolutionary Algorithms

GPS navigators are now present in most vehicles and smartphones. The usual goal of these navigators is to take the user in less time or distance to a destination. However, the global use of navigators in a given city could lead to traffic jams as they have a highly biased preference for some streets. From a general point of view, spreading the traffic throughout the city could be a way of preventing jams and making a better use of public resources. We propose a way of calculating alternative routes to be assigned by these devices in order to foster a better use of the streets. Our experimentation involves maps from OpenStreetMap, real road traffic, and the microsimulator SUMO. We contribute to reducing travel times, greenhouse gas emissions, and fuel consumption. To analyze the sociological aspect of any innovation, we analyze the penetration (acceptance) rate which shows that our proposal is competitive even when just 10% of the drivers are using it.Spanish MINECO project TIN2014-57341-R (http://moveon.lcc.uma.es). FPU grant (FPU13/00954) from the Spanish Ministry of Education, Culture and Sports. University of Malaga. International Campus of Excellence Andalucia TECH

Red Swarm: Smart Mobility in Cities with EAs

This work presents an original approach to regulate traffic by using an on-line system controlled by an EA. Our proposal uses computational spots with WiFi connectivity located at traffic lights (the Red Swarm), which are used to suggest alternative individual routes to vehicles. An evolutionary algorithm is also proposed in order to find a configuration for the Red Swarm spots which reduces the travel time of the vehicles and also prevents traffic jams. We solve real scenarios in the city of Malaga (Spain), thus enriching the OpenStreetMap info by adding traffic lights, sensors, routes and vehicle flows. The result is then imported into the SUMO traffic simulator to be used as a method for calculating the fitness of solutions. Our results are competitive compared to the common solutions from experts in terms of travel and stop time, and also with respect to other similar proposals but with the added value of solving a real, big instance.Ministerio de Economía y Competitividad y FEDER (TIN2011-28194

Flavor-dependent eigenvolume interactions in a hadron resonance gas

Eigenvolume effects in the hadron resonance gas (HRG) model are studied for experimental hadronic yields in nucleus-nucleus collisions. If particle eigenvolumes are different for different hadron species, the excluded volume HRG (EV-HRG) improves fits to multiplicity data. In particular, using different mass~-~volume relations for strange and non-strange hadrons we observe a remarkable improvement in the quality of the fits. This effect appears to be rather insensitive to other details in the schemes employed in the EV-HRG. We show that the parameters found from fitting the data of the ALICE Collaboration in central Pb+Pb collisions at the collision energy $\sqrt{s_{\rm NN}} = 2.76$~TeV entail the same improvement for all centralities at the same collision energy, and for the RHIC and SPS data at lower collision energies. Our findings are put in the context of recent fits of lattice QCD results.Comment: 4 figure

Massive Scaling Limit of beta-Deformed Matrix Model of Selberg Type

We consider a series of massive scaling limits m_1 -> infty, q -> 0, lim m_1 q = Lambda_{3} followed by m_4 -> infty, Lambda_{3} -> 0, lim m_4 Lambda_{3} = (Lambda_2)^2 of the beta-deformed matrix model of Selberg type (N_c=2, N_f=4) which reduce the number of flavours to N_f=3 and subsequently to N_f=2. This keeps the other parameters of the model finite, which include n=N_L and N=n+N_R, namely, the size of the matrix and the "filling fraction". Exploiting the method developed before, we generate instanton expansion with finite g_s, epsilon_{1,2} to check the Nekrasov coefficients (N_f =3,2 cases) to the lowest order. The limiting expressions provide integral representation of irregular conformal blocks which contains a 2d operator lim frac{1}{C(q)} : e^{(1/2) \alpha_1 \phi(0)}: (int_0^q dz : e^{b_E phi(z)}:)^n : e^{(1/2) alpha_2 phi(q)}: and is subsequently analytically continued.Comment: LaTeX, 21 pages; v2: a reference adde

Hall response of interacting bosonic atoms in strong gauge fields: from condensed to FQH states

Interacting bosonic atoms under strong gauge fields undergo a series of phase transitions that take the cloud from a simple Bose-Einstein condensate all the way to a family of fractional-quantum-Hall-type states [M. Popp, B. Paredes, and J. I. Cirac, Phys. Rev. A 70, 053612 (2004)]. In this work we demonstrate that the Hall response of the atoms can be used to locate the phase transitions and characterize the ground state of the many-body state. Moreover, the same response function reveals within some regions of the parameter space, the structure of the spectrum and the allowed transitions to excited states. We verify numerically these ideas using exact diagonalization for a small number of atoms, and provide an experimental protocol to implement the gauge fields and probe the linear response using a periodically driven optical lattice. Finally, we discuss our theoretical results in relation to recent experiments with condensates in artificial magnetic fields [ L. J. LeBlanc, K. Jimenez-Garcia, R. A. Williams, M. C. Beeler, A. R. Perry, W. D. Phillips, and I. B. Spielman, Proc. Natl. Acad. Sci. USA 109, 10811 (2012)] and we analyze the role played by vortex states in the Hall response.Comment: 10 pages, 7 figure

Subconjunctival delivery of p75NTR antagonists reduces the inflammatory, vascular, and neurodegenerative pathologies of diabetic retinopathy

The p75NTR is a novel therapeutic target validated in a streptozotocin mouse model of diabetic retinopathy. Intravitreal (IVT) injection of small molecule p75NTR antagonist THX-B was therapeutic and resolved the inflammatory, vascular, and neurodegenerative phases of the retinal pathology. To simplify clinical translation, we sought a superior drug delivery method that circumvents risks associated with IVT injections. METHODS. We compared the pharmacokinetics of a single 40 lg subconjunctival (SCJ) depot to the reported effective 5 lg IVT injections of THX-B. We quantified therapeutic efficacy, with endpoints of inflammation, edema, and neuronal death. RESULTS. The subconjunctival depot affords retinal exposure equal to IVT injection, without resulting in detectable drug in circulation. At week 2 of diabetic retinopathy, the SCJ depot provided therapeutic efficacy similar to IVT injections, with reduced inflammation, reduced edema, reduced neuronal death, and a long-lasting protection of the retinal structure. CONCLUSIONS. Subconjunctival injections are a safe and effective route for retinal delivery of p75NTR antagonists. The subconjunctival route offers an advantageous, less-invasive, more compliant, and nonsystemic method to deliver p75NTR antagonists for the treatment of retinal diseases.Fil: Galan, Alba. Mc Gill University. Lady Davis Research Intitute; CanadáFil: Barcelona, Pablo Federico. Mc Gill University. Lady Davis Research Intitute; Canadá. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; ArgentinaFil: Nedev, Hinyu. Mc Gill University. Lady Davis Research Intitute; CanadáFil: Sarunic, Marinko V.. University Fraser Simon; CanadáFil: Jian, Yifan. University Fraser Simon; CanadáFil: Saragovi, H. Uri. Mc Gill University. Lady Davis Research Intitute; Canad

Entanglement susceptibility: Area laws and beyond

Generic quantum states in the Hilbert space of a many body system are nearly maximally entangled whereas low energy physical states are not; the so-called area laws for quantum entanglement are widespread. In this paper we introduce the novel concept of entanglement susceptibility by expanding the 2-Renyi entropy in the boundary couplings. We show how this concept leads to the emergence of area laws for bi-partite quantum entanglement in systems ruled by local gapped Hamiltonians. Entanglement susceptibility also captures quantitatively which violations one should expect when the system becomes gapless. We also discuss an exact series expansion of the 2-Renyi entanglement entropy in terms of connected correlation functions of a boundary term. This is obtained by identifying Renyi entropy with ground state fidelity in a doubled and twisted theory.Comment: minor corrections, references adde

El tejido interactivo de la organización laboral : la dualidad formal-informal

El trabajo argumenta un conjunto de reflexiones teóricas que validan el papel y la importancia del estudio de la informalidad para entender el funcionamiento organizacional. A partir de la dualidad esencial de las Organizaciones como sistemas funcionales y humanos la informalidad se presenta como una clave para entender el lado humano de la Organización. Visualizándola a su vez como un gran tejido interactivo que engloba un conjunto de redes sociales interconectadas, podemos ganar una nueva y más compleja comprensión de la dinámica humana y la forma en que se vincula a la dinámica funcional

The Classical Relativistic Quark Model in the Rest-Frame Wigner-Covariant Coulomb Gauge

The system of N scalar particles with Grassmann-valued color charges plus the color SU(3) Yang-Mills field is reformulated on spacelike hypersurfaces. The Dirac observables are found and the physical invariant mass of the system in the Wigner-covariant rest-frame instant form of dynamics (covariant Coulomb gauge) is given. From the reduced Hamilton equations we extract the second order equations of motion both for the reduced transverse color field and the particles. Then, we study this relativistic scalar quark model, deduced from the classical QCD Lagrangian and with the color field present, in the N=2 (meson) case. A special form of the requirement of having only color singlets, suited for a field-independent quark model, produces a ``pseudoclassical asymptotic freedom" and a regularization of the quark self-energy.Comment: 81 pages, RevTe

On the correlation between fragility and stretching in glassforming liquids

We study the pressure and temperature dependences of the dielectric relaxation of two molecular glassforming liquids, dibutyl phtalate and m-toluidine. We focus on two characteristics of the slowing down of relaxation, the fragility associated with the temperature dependence and the stretching characterizing the relaxation function. We combine our data with data from the literature to revisit the proposed correlation between these two quantities. We do this in light of constraints that we suggest to put on the search for empirical correlations among properties of glassformers. In particular, argue that a meaningful correlation is to be looked for between stretching and isochoric fragility, as both seem to be constant under isochronic conditions and thereby reflect the intrinsic effect of temperature