291 research outputs found

    Dynamics of Controlled Hybrid Systems of Aerial Cable-Ways

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    Dynamics of the hybrid systems of aerial cable-ways is investigated. The eigenvalue problems are considered for such hybrid systems with different assumptions. An overview of different methods for eigenvalue problems is given. In the research, the method of the normal fundamental systems is applied, which turns out to be very effective for the considered problems. Changes of dynamical characteristics of the systems depending on the controlled parameter are studied.Comment: Accepted (15-May-2006) to the Proceedings of the "International Conference of Hybrid Systems and Applications", The University of Louisiana, Lafayette, LA, USA, May 22-26 2006, to be published in the journal "Nonlinear Analysis: Hybrid Systems and Applications

    Analysis of the Accuracy of Prediction of the Celestial Pole Motion

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    VLBI observations carried out by global networks provide the most accurate values of the precession-nutation angles determining the position of the celestial pole; as a rule, these results become available two to four weeks after the observations. Therefore, numerous applications, such as satellite navigation systems, operational determination of Universal Time, and space navigation, use predictions of the coordinates of the celestial pole. In connection with this, the accuracy of predictions of the precession- nutation angles based on observational data obtained over the last three years is analyzed for the first time, using three empiric nutation models---namely, those developed at the US Naval Observatory, the Paris Observatory, and the Pulkovo Observatory. This analysis shows that the last model has the best of accuracy in predicting the coordinates of the celestial pole. The rms error for a one-month prediction proposed by this model is below 100 microarcsecond.Comment: 13 p

    On rotational solutions for elliptically excited pendulum

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    The author considers the planar rotational motion of the mathematical pendulum with its pivot oscillating both vertically and horizontally, so the trajectory of the pivot is an ellipse close to a circle. The analysis is based on the exact rotational solutions in the case of circular pivot trajectory and zero gravity. The conditions for existence and stability of such solutions are derived. Assuming that the amplitudes of excitations are not small while the pivot trajectory has small ellipticity the approximate solutions are found both for high and small linear damping. Comparison between approximate and numerical solutions is made for different values of the damping parameter.Comment: 16 pages, 5 figures, 1 tabl

    Haemopoietic System of the Anurans: the Role of Bone Marrow and Liver

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    The haemopoietic activity of the frog, Pelophylax ridibundus was investigated during the year. Liver and bone marrow myelograms were examined in the different seasons using the special indexes and coefficients. It was shown the presence of the erythroid and granulocytic differentiation during the year in the both organs. In the bone marrow is changing the total number of the non-diferentiated haemopoietic cells, but ratio between erythroid and granulocytic progenitors is stabile. The haemopoietic activity of the liver has more prominent season variation in comparison with the marrow, but their total significance is comparable. The erythrocytic differentiation is more prominent during the summer and autumn, but granulocytic one took place in the spring and summer.Гемопоэтическую активность костного мозга и печени озерной лягушки (Pelophylax ridibundus) исследовали в течение года. С помощью специальных коэффициентов и показателей анализировались миелограммы костного мозга и печени, определенные в различные сезоны. Показано наличие в обоих органах дифференцировки эритроидного и миелоидного ростков в течение года. В костном мозге изменяется общее количество недифференцированных предшественников кроветворения, но соотношение эритроидных и гранулоцитарных предшественников остается стабильным. Гемопоэтическая активность печени имеет более выраженные сезонные колебания, хотя её общее значение для гемопоэза сравнимо с костным мозгом. Дифференцировка эритроцитов более выражена летом и осенью, а дифференцировка гранулоцитов — весной и летом

    The Issues and Challenges of CLIL Implementation in Higher Education: Teachers’ Beliefs in the Ukrainian Context

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    The purpose of CLIL in higher education is to increase the level of students’ both professional knowledge and foreign language competence. While implementing CLIL, it is important to take into account teachers’ beliefs on a point, since they can either accelerate or inhibit the CLIL effectiveness. The purpose of the research is to study the Ukrainian teachers’ beliefs, motivation and ideas concerning the implementation of the CLIL approach in the Ukrainian higher education. The theoretical and methodological basis of research was formed on comprehensive analysis of literature sources. The experimental work included: 1) obtaining the research data (a survey was conducted in which more than 160 teachers from different universities of Ukraine took part); 2) analyzing the obtained data statistically (conjugation tables, asymptotic approximation method, and Pearson’s statistical criterion χ2 were used); 3) identifying influential factors in the CLIL implementation (factor analysis was used). The analysis shows there is relationship between the teachers' subject background and their beliefs on the CLIL appropriateness. The study disproves the influence of the teachers’ pedagogical experience on their views on the CLIL implementation. These findings are confirmed by a factor analysis indicating the importance of appropriate learning materials for CLIL, teachers’ specialty, their professional preferences, the importance of flexibility in choosing the CLIL strategy, depending on students’ content knowledge and language skills. The study indicates challenges for the efficient CLIL implementation, and the directions for the change of teachers’ motivation regarding the importance of CLIL for modern Ukrainian students

    Employing combination procedures to short-time EOP prediction

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    A well known problem with Earth Orientation Parameters (EOP) prediction is that a prediction strategy proved to be the best for some testing time span and prediction length may not remain the same for other time intervals. In this paper, we consider possible strategies to combine EOP predictions computed using different analysis techniques to obtain a final prediction with the best accuracy corresponding to the smallest prediction error of input predictions. It was found that this approach is most efficient for ultra-short-term EOP forecast.Comment: 7 pages, presented at the IERS Workshop on EOP Combination and Prediction, Warsaw, Poland, 19-21 Oct 200

    METHODOLOGICAL PRINCIPLES OF EVALUATION OF INVESTMENT ATTRACTIVENESS OF THE ENTERPRISE

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    The purpose of the research is a complex of theoretical and applied provisions on the formation, evaluation, and improvement of the methodology of evaluation of the investment attractiveness of enterprises. Methodology. In the process of research, the following methods were used: methods of comparison, analysis and synthesis is used in determining the features of conceptual approaches to the concept of investment attractiveness of an enterprise and the formation of the author’s definition of this category; method of diagnostic evaluation is used in the evaluation of existing models for analysing the investment attractiveness of enterprises; method of expert evaluation is used for the building of flexible limits of levels of investment attractiveness of the enterprise; methods of system and structural analysis is used for developing the basic elements and the general structure of the model of interpretation of the method of graphical integration; the method of graphic integration is used within the construction of graphs of investment attractiveness of enterprises A and B. The aim of the study is to justify of the approach to create a model that can justify of the feasibility of investing and determine the factors and conditions of investment attractiveness of the enterprise for different participants of the investment process. The findings of the study. The results of the research suggested an improved definition of the concept of investment attractiveness of the enterprise, which took into account the following disadvantages of existing approaches to the present essence of the concept: the investment attractiveness of the enterprise is often associated with the system of financial and economic indicators of the activity of enterprise, while not taking into account also an important social and psychological factor, since the very name of the term “investment attractiveness of the enterprise” includes the social-psychological element in the form of the concept of “attractiveness”, which is widely used in economic literature; the subjective view of the potential investor on the fact that the object being considered for investing to satisfy the investor’s expectations regarding the economic or social effect is significant. This aspect is key in determining of concept of investment attractiveness of the enterprise, when choosing an investor of an enterprise to invest its capital for the purpose of investing; it is necessary to achieve consistency and symbiosis between the evaluation of financial and economic, socio-psychological, industrial, innovative, environmental and other factors, which in the complex form the investment attractiveness of the enterprise; using the expression “high level of profitability on investment with minimal risks” is partially incorrect in some definitions of the investment attractiveness of the enterprise since obtaining high profits involves a certain level of risk and each investor knows about this; the importance of increasing the investment attractiveness of the enterprise has the level of involvement of innovation in the activities of the enterprise in the frames of use of investment capital; the targeting of almost all definitions only on high financial and economic indicators, which, depending on the situation, are not always correct. A complex system of indicators for evaluation of the investment attractiveness of an enterprise is proposed, consisting of six groups of indicators (market position, property complex, profitability, financial stability, risks, innovative potential), each of which includes six coefficients determining the level of investment attractiveness for this group. The features and advantages of this system of indicators are: complexity and complementary to standard methods with indicators of the level of investment risk and innovative potential of enterprises; standardization of indicators; unidirectionality of indicators; Flexibility of the recommended limits for each coefficient. The method of graphical integration of the investment attractiveness of the enterprise, which has several advantages over other methods, proposed in the scientific literature, is offered because: it is a combination that includes the advantages of an integral method, as well as a market, and partially matrix method; it allows quantifying various aspects of economic activity of the enterprise by the elementary calculation of a certain number of coefficients; it does not require significant time to spend on the evaluation; it has a mathematical justification since the final indicators for comparing the investment attractiveness of several enterprises are calculated using the numerical integration method; it has the flexibility of determining the level of investment attractiveness of an enterprise by incorporating into the methodology in accordance with the socio-psychological component of the concept of investment attractiveness and the interests of the investor; gives a visual interpretation of the results of investment attractiveness assessment

    Analysis of the dynamics of Staphylococcus aureus binding to white blood cells using whole blood assay and geno-to-pheno mapping

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    Given that binding and internalization of bacteria to host cells promotes infections and invasion, we aimed at characterizing how various S. aureus isolates adhere to and are internalized by different white blood cells. In particular, the role of genetic determinants on the association kinetics should be unveiled. A flow cytometric (FACS) whole blood assay with fluorescently labelled isolates was applied to 56 clinical S. aureus isolates. This phenotypic data was then linked to previously obtained genotyping data (334 genes) with the help of a redescription mining algorithm. Professional phagocytes showed a time-dependent increase of bacterial adhesion and internalization. Isolates showing higher affinity to granulocytes were associated with lower binding to monocytes. In contrast binding activity between S. aureus and lymphocytes could be subdivided into two phases. Preliminary binding (phase 1) was highest directly after co-incubation and was followed by S. aureus detachment or by sustained binding of a small lymphocyte subset (phase 2). Strain-dependent low granulocyte binding was observed for clonal complex 5 (CC5) isolates (MRSA), as compared to CC30 and CC45 (MSSA). S. aureus isolates associated with low granulocyte phagocytosis were characterized by the presence (cap8, can) and the absence (sasG, lukD, isdA, splA, setC) of specific hybridization signals

    Залежність синтезу меланіну чорними дріжджами Psedonadsoniella brunnea від кількості джерела вуглецю в культуральному середовищі

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    The aim of the study was to determine the effect of carbon source content in the culture medium on melanin synthesis by black yeast Pseudonadsoniella brunnea 470 FCKU.Materials and Methods: Cultivation of Pseudonadsoniella brunnea strain was carried out on liquid nutrient medium, the main component of which was barley-malt extract. The concentration of the carbon source (carbohydrates) in the barley-malt extract solution was set at 2.0; 4.0; 6.0 and 8.0 % for the AST-2 areometer-sugar meter. 0.05 % L-tyrosine and 1 % peptone enzymatic were added to these media. 0.05 % L-tyrosine and 1 % peptone enzymatic were added to these media. The acidity of the media at the level of 1-1.5 was carried out using sulfuric acid.Result. Studies have shown that the amount of synthesized melanin by a strain of black yeast fungi Pseudonadsoniella brunnea 470 FCKU depends on the amount of carbon source in the culture medium. The amount of melanin synthesized by the Pseudonadsoniella brunnea strain increased by 5.8 and 5.1 times, with a decrease in the content of reducing sugars in the culture medium by 2 and 4 times, respectively.Conclusions: Cultivation of Pseudonadsoniella brunnea 470 FCKU strain at low pH and carbon source content results in its protective function in the form of melanin release into the culture medium. The highest amount of melanin (394.03 mg/l) by strain Pseudonadsoniella brunnea was synthesized when carbon source was introduced into the culture medium at a concentration of 4.0 % by hydrometer, which corresponds to the content of 2.4-2.52 % reducing sugars (predominantly maltose)Целью работы было определение влияния содержания источника углерода в культуральной среде на синтез меланина черными дрожжами Pseudonadsoniella brunnea 470 FCKU.Материалы и методы: культивирование штамма Pseudonadsoniella brunnea осуществляли на жидкой питательной среде, основной составляющей которой был ячменно-солодовый экстракт. Концентрацию источника углерода (углеводов) в растворе ячменно-солодового экстракта устанавливали на уровне 2,0; 4,0; 6,0 и 8,0 % согласно показаниям ареометра-сахарометра АСТ-2. В эти среды добавляли 0,05 % L-тирозина и 1 % пептона ферментативного. Регулирование кислотности питательных сред на уровне 1-1,5 осуществляли с помощью серной кислоты.Результаты. В результате проведенных исследований установлено, что количество синтезированного меланина штаммом черных дрожжеподобных грибов Pseudonadsoniella brunnea 470 FCKU зависит от количества источника углерода в культуральной среде. При условии уменьшения в культуральной среде содержания редуцирующих сахаров в 2 и 4 раза количество меланина, синтезированного штаммом Pseudonadsoniella brunnea, увеличивалось в 5,8 и 5,1 раза, соответственно.Выводы. Культивирование штамма Pseudonadsoniella brunnea 470 FCKU в условиях низких показателей рН и содерания источника углерода приводит к реализации его защитной функции в виде выделения меланина в культуральную среду. Наибольшее количество меланина (394,03 мг/л) штамм Pseudonadsoniella brunnea синтезировал в условиях внесения в культуральную среду источника углерода в концентрации 4,0 % (согласно показаниям ареометра), что соответствует содержанию 2,4-2,52 % редуцирующих сахаров (преимущественно мальтозы)Метою роботи було визначення впливу вмісту джерела вуглецю в культуральному середовищі на синтез меланіну чорними дріжджами Pseudonadsoniella brunnea 470 FCKU.Матеріали та методи: культивування штаму Pseudonadsoniella brunnea здійснювали на рідкому поживному середовищі, основною складовою якого був ячмінно-солодовий екстракт. Концентрацію джерела вуглецю (вуглеводів) в розчині ячмінно-солодового екстракту встановлювали на рівні 2,0; 4,0; 6,0 та 8,0 % за ареометром-цукрометром АСТ-2. В ці середовища додавали 0,05 % L-тирозину та 1 % пептону ферментативного. Регулювання кислотності середовищ на рівні 1-1,5 здійснювали за допомогою сірчаної кислоти.Результати дослідження. В результаті проведених досліджень встановлено, що кількість синтезованого меланіну штамом чорних дріжджоподібних грибів Pseudonadsoniella brunnea 470 FCKU залежить від кількості джерела вуглецю в культуральному середовищі. За умов зменшення в культуральному середовищі вмісту редукованих цукрів в 2 та 4 рази кількість меланіну, синтезованого штамом Pseudonadsoniella brunnea, збільшувалась в 5,8 та 5,1 рази, відповідно.Висновки. Культивування штаму Pseudonadsoniella brunnea 470 FCKU за низьких показників рН та вмісту джерела вуглецю призводить до реалізації його захисної функції у вигляді виділення меланіну у культуральне середовище. Найбільшу кількість меланіну (394,03 мг/л) штам Pseudonadsoniella brunnea синтезував при внесенні в культуральне середовище джерела вуглецю в концентрації 4,0 % за ареометром, що відповідає вмісту 2,4-2,52 % редукуючих цукрів (переважно мальтози
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