1,784 research outputs found

    Ground Deformations Observed After 23.10.2011 M\u3csub\u3ew\u3c/sub\u3e 7.2 VAN Earthquake (Turkey)

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    A destructive earthquake with a moment magnitude of 7.2 occurred in the north of the Van province (Turkey) on 23rd October 2011 at 13:41 local time and caused approximately 600 deaths and more than 4000 injuries. Many damaging aftershocks were recorded for more than a month after the main shock including a triggered earthquake (Mw 5.6) located in the southern district of Van, namely Edremit, on November 9th, 2011 which caused additional damage and casualties. After the Mw 7.2 Van earthquake, earthquake-induced ground deformations such as liquefaction and lateral spreading were extensively observed around the shores of Lake Van and in the floodplains of rivers. The Karasu River floodplain, which is one of the major streams in the region, severely suffered from liquefaction and lateral spreading. In this study, a brief overview of the Mw 7.2 Van earthquake as well as earthquake-induced ground deformations is presented. Then, the results of field reconnaissance on liquefaction and lateral spreading features observed in the Karasu River floodplain are explained. Furthermore, subsurface characteristics of liquefied layers are documented considering the data obtained from a borehole drilled just on top of the sand boil after the earthquake. The borehole data indicate that the liquefaction occurred in a sandy zone with very shallow groundwater level in the Karasu River floodplain

    Magnet-retained sectional definitive obturator for an infrastructure maxillectomy patient with limited jaw opening: A clinical report

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    A limited oral opening can be a significant problem for patients who must wear removable dental prostheses while inserting or removing prostheses. The treatment of a patient with an infrastructure maxillectomy due to adenoid cystic carcinoma is presented in this clinical report. A sectional obturator prosthesis retained by magnets was fabricated to deal with trismus, fibrosis, and microstomia. The patient’s esthetic and functional expectations were satisfied. The new generation of magnets with improved technology provide sufficient denture retention for clinical application. However, further follow-up may be necessary to ascertain the long-term usefulness of the magnet-retained obturator prosthesis, because, not only the deformation of the silicone material may continue to progress but also loss of magnetism can occur because of corrosion

    Using the Scanning Fluid Dynamic Gauging Device to Understand the Cleaning of Baked Lard Soiling Layers.

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    Extended or repeated heating of food fats promotes polymerisation reactions that produce difficult-to-remove soil layers. Cleaning of these baked-on/burnt-on fat deposits was investigated using model layers generated by baking lard on 316 stainless steel discs. Rigorous characterisation of the layer material was difficult, as it was insoluble in most solvents. Cleaning was studied using the scanning fluid dynamic gauging technique developed by Gordon et al. (Meas Sci Technol 21:85-103, 2010), which provides non-contact in situ measurement of layer thickness at several sites on a sample in real time. Tests at 50 [Formula: see text]C with alkali (sodium hydroxide, pH 10.4-11) and three surfactant solutions indicated two removal mechanisms, related to the (1) roll-up and (2) dispersion mechanisms reported for oily oils, namely (1) penetration of solvent at the soil-liquid interface, resulting in detachment of the soil layer as a coherent film, observed with linear alkylbenzene sulfonic acid (LAS) and Triton X-100 and aqueous sodium hydroxide at pH 10.4-11; and (2) the breakdown promoted by the agent penetrating through the layer, observed with cetyl trimethyl ammonium bromide (CTAB), in which CTAB antagonised the cleaning action of LAS.An EPSRC studentship for AA and project support from Procter and Gamble Ltd is gratefully acknowledged.This is the final version of the article. It first appeared from Springer via http://dx.doi.org/10.1007/s11743-015-1737-

    Farklı tipteki aljinat dental ölçü maddelerinin sitotoksisite yönünden değerlendirilmesi

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    Purpose: The aim of this study was to assess the cytotoxicity of different types of alginate impression materials. Material and Method: Cavex CA37, A3KROM, ALGINPLUS FAST ve ORALGHINE alginate impression materials were used. According to the manufacturer’s instructions, alginates were mixed with serum physiological to obtain alginate specimens. Specimens were performed in sterile with ethylene oxide gas and then placed on to the L929 fibroblast cell culture. According to the 1999 ISO 10993-5 protochols, cytotoxicity were determined by means of agar overley test. Results: According to the lisis of the cells, ORALGH<NE and Cavex CA37; 4-4-4-5-5, ALGINPLUS and A3KROM; 2-3-3-3-2 were determined. Values of the cytotoxicity were determined 4,4 for ORALGH<NE and Cavex CA37, whereas 2,6 for ALGINPLUS and A3KROM. Conclusion: Cytotoxicity degree of the alginates were different because of the composition of the alginates. It was determined that ORALGHINE and Cavex CA37 were severely cytotoxic, ALGINPLUS and A3KROM were moderately cytotoxic. ÖZET Amaç: Bu in vitro çalışmanın amacı, farklı tipteki aljinat ölçü maddelerini sitotoksisite yönünden değerlendirmektir. Gereç ve Yöntem: Farklı tipteki dört aljinat, Cavex CA37, A3KROM, ALGINPLUS FAST ve ORALGHINE, üretici firmaların talimatlar doğrultusunda belirtilen oranlarda, serum fizyolojik ile karıştırılarak aljinat numuneleri hazırlandı. Hazırlanan numuneler etilen oksit gazıyla steril edildi ve L929 fibroblast hücre serisi kullanılarak elde edilen kültüre yerleştirildi. Agar overley testi kullanılarak sitotoksisitenin belirlenmesinde ISO 1999 yıl 10993-5 numaral protokolü takip edildi. Bulgular: Hücrelerin lizis miktarına göre yapılan puanlama değerleri ORALGHINE ve Cavex CA37 için; 4-4-4-5-5, ALGINPLUS ve A3KROM için; 2-3-3-3-2 olarak tespit edildi. Sitotoksisite değerleri de ORALGHINE ve Cavex CA37 için 4.4, ALGINPLUS ve A3KROM için ise 2.6 olarak bulundu. Sonuçlar: İçerik farklılığına bağlı olarak aljinatlarn sitotoksisite değerleri farklılık göstermiştir. ORALGHINE ve Cavex CA37’nin belirgin derecede sitotoksik olduğu, ALGINPLUS ve A3KROM’ un ise makul derecede sitotoksik olduğu belirlendi. Anahtar kelimeler: Sitotoksisite, aljinat

    ARK AKIMI VE ARK GERİLİMİNİN BAĞLANTI MUKAVEMETİ ÜZERİNE ETKİLERİNİN ARAŞTIRILMASI

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    Bu çalışmada gazaltı kaynak parametrelerinden ark akımı ve ark gerilimi dışında kalan parametreler sabit tutularak, çeşitli kaynak bağlantıları elde edilmiştir. Çalışmanın ana hedefi, sanayide özellikle imalat sektöründe sıklıkla kullanılan elle gazaltı kaynak yöntemi için, ark akımı ve ark geriliminin bağlantının çekme mukavemeti üzerindeki etkisini görmektir. Bu bağlantılarda ana malzeme olarak, mobil vinç imalatında sıkça kullanılan S700MC kalite malzeme seçilmiştir. Elde edilen bağlantıların, kaynak dikiş profilleri ve kaynak nüfuziyetleri incelendikten sonra, çekme mukavemetinin tespit edilmesi amacıyla, bağlantılardan çekme numuneleri çıkartılıp, çekme deneyleri uygulanmıştır. Çekme deneyleri sonucunda en çarpıcı sonuç, özellikle yüksek kaynak gerilimleri ile elde edilen bağlantılarda, yüksek gerilim sonucu oluşan uzun ark boyunda meydana gelmiştir. Uzun ark boyu nedeniyle kaynak dikişinin genişliği artmış ve nüfuziyeti azalmıştır. Ayrıca geniş dikiş profili sonucu hızlı soğuma meydana gelmiş ve iç gerilmeler artmıştır. Bu nedenlerin doğal sonucu olarak da uzun ark boyu ile elde edilen çekme mukavemet değerleri, kısa ve orta ark boyuna oranla yaklaşık %15 daha düşük sonuçlar vermiştir

    Comparison of Clinical and Hemodynamic Effects of Isoflurane and Sevoflurane Anesthesia in Calves

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    Background: Inhalation anesthesia is the preferred method for use on many animal species, including ruminants, due to its superiority over the injectable anesthetics. The most commonly used inhalation anesthetics are isoflurane and sevoflurane The aim of the study was to investigate the effects of isoflurane and sevoflurane anesthesia on the cardiovascular system of calves.Materials, Methods & Results: A total of 20 calves (11 male, 9 female) between 1 and 6 months in age and 50 to 85 kg in body weight were used. The calves were divided randomly into two groups of 10 each, with one group being administered isoflurane and the other sevoflurane. An intramuscular dosage of 0.1 mg/kg of xylazine was administered to the calves as premedication. Induction was performed 10 min after calves were given an intramuscular dosage of 4 mg/kg of ketamine. Inhalation anesthesia was maintained with isoflurane or sevoflurane in 100% oxygen saturation. Before anesthesia, after induction and at intervals of 5, 10, 15, 20, 25, 30, 45, and 60 min of anesthesia, the body temperature, heart rate, and respiratory rate of the calves were recorded. Additionally, before anesthesia, after induction and at intervals of 15, 30, 45, and 60 min of anesthesia, serum electrolyte (Na+, Ca++, K+, Mg++) and blood gases (pH, pCO2, pO2, HCO3-, TCO2, O2Sat, HCT) were evaluated from blood samples taken from both groups. The second derivation, durations and amplitudes of the P and T waves, the durations and amplitudes of the QRS complex, and the durations of PQ and QT intervals were evaluated on the ECGs recorded before anesthesia, after induction and during anesthesia. Following anesthesia termination, the extubation time and the time it took for straightening of the head and standing up were recorded. Decrease in heart rate and body temperature were found significant in two of the groups. Decrease in respiratory rate compared to initial values after premedication was statistically significant for both groups. However, during anesthesia, an increase occurred. This incresae in respiration rate was not statistically significant compared to initial values. The incease in the values of pCO2, pO2, HCO3 and the decrease in the values of pH and Hct comparing the initial values was found statistically significant in both groups.Discussion: In ruminants, isoflurane has an induction concentration of 3-5% and an anesthetic concentration of 1.5-3%, while sevoflurane has an induction concentration of 4-6% and an anesthetic concentration of 2.5-4%. In this study, the concentration of isoflurane was 2.3% (2-5) and the of sevoflurane was 4.07% (3-5) for surgery. In the isoflurane group, extubation, straightening of the head and standing up times were 12.40 ± 3.77 min, 20.4 ± 1.57 min, and 30.80 ± 1.89 min, respectively. In the sevoflurane group, extubation, straightening of the head and standing up times were 13.40 ± 4.99, 19.2 ± 1.49, and 28.0 ± 1.83 min, respectively. Although the calves in the isoflurane group were extubated earlier than those of the sevoflurane group, the time elapsed for straightening of the head and standing up were longer than that of the sevoflurane group. The anesthesia protocol provided a smooth anesthetic administration, general anesthesia and awakening. In conclusion, the effects of isoflurane and sevoflurane anesthesia on the cardiovascular and respiratory system were similar, and although the changes that emerged during anesthesia were statistically significant, it was nonetheless found that the changes were within the physiological limits

    Sodium Nitroprusside as a Nitric Oxide Donor in a Rat Intestinal Ischemia-Reperfusion Model

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    AIM: The aim of this study was to investigate the efficacy of sodium nitroprusside in the reduction of the intestinal ischemiareperfusion injury as a nitric oxide donor after intraperitoneal administration. METHODS: The histopathological examinations and tissue malonyldialdehyde levels of 35 Wistar albino rats that were subjected to ischemia-reperfusion, were performed in 5 groups. The groups include Control, Ischemia -reperfusion, Sodium nitroprusside, NG-Nitro-L-Arginine Methyl Ester (L-NAME) and Sodium nitroprusside+L-NAME. Each rat was subjected to ischemia for 40 minutes and reperfusion for 30 minutes, except the control group. The medications were done intraperitoneally as saline 4 ml/kg, Sodium nitroprusside 5 mg/kg, L-NAME 10 mg/kg just before reperfusions. RESULTS: Significant tissue injury in histological sections and an increase in tissue levels of Malonyldialdehyde was detected in the I/R group. The efficacy of intraperitoneal administration of Sodium nitroprusside in both Sodium nitroprusside alone and Sodium nitroprusside+L-NAME groups was found statistically significant for the reducing of injury scores (p<0.05). The difference between the Ischemia/reperfusion and Sodium nitroprusside groups was found statistically significant as in the Ischemia/reperfusion and Sodium nitroprusside+L-NAME groups due to the tissue Malonyldialdehyde levels (p<0.05). There was no statistical difference between Ischemia/reperfusion and L-NAME groups. CONCLUSION: Ischemia/reperfusion induced injury might be reduced by the intraperitoneal administration of Sodium nitroprusside, even in the presence of L-NAME, in the rat intestinal model

    Feasibility of a tubularised incised-plate urethroplasty with double de-epithelised dartos flaps in a failed hypospadias repair: A preliminary report

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    Background: Reoperation for failed hypospadias has been considered to be seriously problematic. The dense fibrotic tissue causes difficulties in wound healing and increases the rate of complications. The tubularised incised-plate urethroplasty (TIPU) method has become a preferred method for all varieties of hypospadias in the past decade. However, fistulas are still one of the most common complications of this technique. The aim of this paper was to present the preliminary results of TIPU procedure with double de-epithelised dartos flaps in failed hypospadias repair. Materials and Methods: All patients were treated between January 2009 and August 2010 by the same procedure, utilising TIPU with double de-epithelised dartos flaps. Vascularised ventral dartos flaps harvested from each side of the penis with their vascular supply were transposed to cover the suture line by wrapping them from either side of the penis. Results: There were 21 boys with failed hypospadias: 20 had previously undergone TIPU, and one Koyanagi repair. Patients presented with very large fi stulas in four and dehiscence in 17. Repair of the failed hypospadias using TIPU with double de-epithelised dartos flaps was quite successful, with no fistula recurrence or dehiscence observed. Conclusion: The preliminary results showed that TIPU with double de-epithelised dartos flaps is a useful method of successfully repairing failed hypospadias

    Persistent High Postoperative Carcinoembryonic Antigen in Colorectal Cancer Patients- Is it Important?

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    INTRODUCTION: Evaluation of pre- and postoperative serum CEA levels together has seldom been assessed for the prognosis of colorectal cancer (CRC). OBJECTIVE: To concurrently evaluate pre- and postoperative CEA as factors of relapse and survival. METHODS: The study consisted of 114 patients who had undergone surgery from February 2002 to June 2006 for CRC. All patients were classified into four groups according to their pre- and postoperative CEA levels. Data obtained for clinicopathologic parameters, lymph node metastasis, stage, recurrence, and CEA levels were analyzed to determine their association with survival. Multivariate analysis by the Cox proportional hazard regression model was performed to identify the independent prognostic factors associated with survival. RESULTS: Postoperative serum CEA levels remained high in Group 3 (n = 32). Nineteen patients (59.3%) demonstrated a detectable cause for persistent high CEA levels, while the reasons for those in the other thirteen patients (40.6%) remained obscure. Abnormal preoperative CEA levels significantly correlated with the depth of tumor invasion, lymph node metastasis, TNM stage, and recurrence (p < 0.05). Abnormal postoperative CEA levels were significantly related to the depth of tumor invasion, TNM stage, and postoperative relapse (p<0.05). Patients in Group 3 demonstrated the worst survival rate. Abnormal postoperative CEA levels, lymph node metastasis, and location of the tumor were independent prognostic factors for survival. CONCLUSION: The survival of patients with high postoperative CEA levels due to unknown reasons may be extended if they are exhaustively tested with sensitive diagnostic methods and treated at an early stage
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