1,521 research outputs found

    Homogeneous metamaterial description of localised spoof plasmonics in spiral geometries

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    It has been recently shown that ultrathin spiral metamaterials can support localized spoof plasmon modes whose resonant wavelength is much larger than the size of the structure. Here, an analytical model is developed to describe the electromagnetic properties of the two-dimensional version of these devices: a perfect conducting wire corrugated by spiral grooves. The emergence of localized spoof plasmons in this geometry is quantitatively investigated. Calculations show that these modes can be engineered through the spiral angle and the number of grooves. The theory also allows us to elucidate the contribution of magnetic and electric localized spoof plasmons to the optical response of these metamaterial devices. Finally, experimental evidence of the existence of these modes in extremely thin textured copper disks is also presented

    Integrative analyses of transcriptome sequencing identify novel functional lncRNAs in esophageal squamous cell carcinoma.

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    Long non-coding RNAs (lncRNAs) have a critical role in cancer initiation and progression, and thus may mediate oncogenic or tumor suppressing effects, as well as be a new class of cancer therapeutic targets. We performed high-throughput sequencing of RNA (RNA-seq) to investigate the expression level of lncRNAs and protein-coding genes in 30 esophageal samples, comprised of 15 esophageal squamous cell carcinoma (ESCC) samples and their 15 paired non-tumor tissues. We further developed an integrative bioinformatics method, denoted URW-LPE, to identify key functional lncRNAs that regulate expression of downstream protein-coding genes in ESCC. A number of known onco-lncRNA and many putative novel ones were effectively identified by URW-LPE. Importantly, we identified lncRNA625 as a novel regulator of ESCC cell proliferation, invasion and migration. ESCC patients with high lncRNA625 expression had significantly shorter survival time than those with low expression. LncRNA625 also showed specific prognostic value for patients with metastatic ESCC. Finally, we identified E1A-binding protein p300 (EP300) as a downstream executor of lncRNA625-induced transcriptional responses. These findings establish a catalog of novel cancer-associated functional lncRNAs, which will promote our understanding of lncRNA-mediated regulation in this malignancy

    Mammalian Genes Preferentially Co-Retained in Radiation Hybrid Panels Tend to Avoid Coexpression

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    Coexpression has been frequently used to explore modules of functionally related genes in eukaryotic genomes. However, we found that genetically interacting mammalian genes identified through radiation hybrid (RH) genotypes tend not to be coexpressed across tissues. This pattern remained unchanged after controlling for potential confounding factors, including chromosomal linkage, chromosomal distance, and gene duplication. Because >99.9% of the genetically interacting genes were identified according to the higher co-retention frequencies, our observation implies that coexpression is not necessarily an indication of the need for the co-presence of two genes in the genome, which is a prerequisite for cofunctionality of their coding proteins in the cell. Therefore, coexpression information must be applied cautiously to the exploration of the functional relatedness of genes in a genome

    The Effect of Transposable Element Insertions on Gene Expression Evolution in Rodents

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    Background:Many genomes contain a substantial number of transposable elements (TEs), a few of which are known to be involved in regulating gene expression. However, recent observations suggest that TEs may have played a very important role in the evolution of gene expression because many conserved non-genic sequences, some of which are know to be involved in gene regulation, resemble TEs. Results:Here we investigate whether new TE insertions affect gene expression profiles by testing whether gene expression divergence between mouse and rat is correlated to the numbers of new transposable elements inserted near genes. We show that expression divergence is significantly correlated to the number of new LTR and SINE elements, but not to the numbers of LINEs. We also show that expression divergence is not significantly correlated to the numbers of ancestral TEs in most cases, which suggests that the correlations between expression divergence and the numbers of new TEs are causal in nature. We quantify the effect and estimate that TE insertion has accounted for ~20% (95% confidence interval: 12% to 26%) of all expression profile divergence in rodents. Conclusions:We conclude that TE insertions may have had a major impact on the evolution of gene expression levels in rodents

    Spin-Imbalance in a One-Dimensional Fermi Gas

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    Superconductivity and magnetism generally do not coexist. Changing the relative number of up and down spin electrons disrupts the basic mechanism of superconductivity, where atoms of opposite momentum and spin form Cooper pairs. Nearly forty years ago Fulde and Ferrell and Larkin and Ovchinnikov proposed an exotic pairing mechanism (FFLO) where magnetism is accommodated by formation of pairs with finite momentum. Despite intense theoretical and experimental efforts, however, polarized superconductivity remains largely elusive. Here we report experimental measurements of density profiles of a two spin mixture of ultracold 6Li atoms trapped in an array of one dimensional (1D) tubes, a system analogous to electrons in 1D wires. At finite spin imbalance, the system phase separates with an inverted phase profile in comparison to the three-dimensional case. In 1D we find a partially polarized core surrounded by wings composed of either a completely paired BCS superfluid or a fully polarized Fermi gas, depending on the degree of polarization. Our observations are in quantitative agreement with theoretical calculations in which the partially polarized phase is found to be a 1D analogue of the FFLO state. This study demonstrates how ultracold atomic gases in 1D may be used to create non-trivial new phases of matter, and also paves the way for direct observation and further study of the FFLO phase.Comment: 30 pages, 7 figure

    Study of J/ψJ/\psi and ψ(3686)Σ(1385)0Σˉ(1385)0\psi(3686)\rightarrow\Sigma(1385)^{0}\bar\Sigma(1385)^{0} and Ξ0Ξˉ0\Xi^0\bar\Xi^{0}

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    We study the decays of J/ψJ/\psi and ψ(3686)\psi(3686) to the final states Σ(1385)0Σˉ(1385)0\Sigma(1385)^{0}\bar\Sigma(1385)^{0} and Ξ0Ξˉ0\Xi^0\bar\Xi^{0} based on a single baryon tag method using data samples of (1310.6±7.0)×106(1310.6 \pm 7.0) \times 10^{6} J/ψJ/\psi and (447.9±2.9)×106(447.9 \pm 2.9) \times 10^{6} ψ(3686)\psi(3686) events collected with the BESIII detector at the BEPCII collider. The decays to Σ(1385)0Σˉ(1385)0\Sigma(1385)^{0}\bar\Sigma(1385)^{0} are observed for the first time. The measured branching fractions of J/ψJ/\psi and ψ(3686)Ξ0Ξˉ0\psi(3686)\rightarrow\Xi^0\bar\Xi^{0} are in good agreement with, and much more precise, than the previously published results. The angular parameters for these decays are also measured for the first time. The measured angular decay parameter for J/ψΣ(1385)0Σˉ(1385)0J/\psi\rightarrow\Sigma(1385)^{0}\bar\Sigma(1385)^{0}, α=0.64±0.03±0.10\alpha =-0.64 \pm 0.03 \pm 0.10, is found to be negative, different to the other decay processes in this measurement. In addition, the "12\% rule" and isospin symmetry in the J/ψJ/\psi and ψ(3686)ΞΞˉ\psi(3686)\rightarrow\Xi\bar\Xi and Σ(1385)Σˉ(1385)\Sigma(1385)\bar{\Sigma}(1385) systems are tested.Comment: 11 pages, 7 figures. This version is consistent with paper published in Phys.Lett. B770 (2017) 217-22

    Measurement of azimuthal asymmetries in inclusive charged dipion production in e+ee^+e^- annihilations at s\sqrt{s} = 3.65 GeV

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    We present a measurement of the azimuthal asymmetries of two charged pions in the inclusive process e+eππXe^+e^-\rightarrow \pi\pi X based on a data set of 62 pb1\rm{pb}^{-1} at the center-of-mass energy s=3.65\sqrt{s}=3.65 GeV collected with the BESIII detector. These asymmetries can be attributed to the Collins fragmentation function. We observe a nonzero asymmetry, which increases with increasing pion momentum. As our energy scale is close to that of the existing semi-inclusive deep inelastic scattering experimental data, the measured asymmetries are important inputs for the global analysis of extracting the quark transversity distribution inside the nucleon and are valuable to explore the energy evolution of the spin-dependent fragmentation function.Comment: 7 pages, 5 figure

    Observation of an anomalous line shape of the ηπ+π\eta^{\prime}\pi^{+}\pi^{-} mass spectrum near the ppˉp\bar{p} mass threshold in J/ψγηπ+πJ/\psi\rightarrow\gamma\eta^{\prime}\pi^{+}\pi^{-}

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    Using 1.09×1091.09\times10^{9} J/ψJ/\psi events collected by the BESIII experiment in 2012, we study the J/ψγηπ+πJ/\psi\rightarrow\gamma\eta^{\prime}\pi^{+}\pi^{-} process and observe a significant abrupt change in the slope of the ηπ+π\eta^{\prime}\pi^{+}\pi^{-} invariant mass distribution at the proton-antiproton (ppˉp\bar{p}) mass threshold. We use two models to characterize the ηπ+π\eta^{\prime}\pi^{+}\pi^{-} line shape around 1.85 GeV/c21.85~\text{GeV}/c^{2}: one which explicitly incorporates the opening of a decay threshold in the mass spectrum (Flatt\'{e} formula), and another which is the coherent sum of two resonant amplitudes. Both fits show almost equally good agreement with data, and suggest the existence of either a broad state around 1.85 GeV/c21.85~\text{GeV}/c^{2} with strong couplings to ppˉp\bar{p} final states or a narrow state just below the ppˉp\bar{p} mass threshold. Although we cannot distinguish between the fits, either one supports the existence of a ppˉp\bar{p} molecule-like state or bound state with greater than 7σ7\sigma significance

    Measurement of the e+eπ+π\mathrm e^+\mathrm e^-\rightarrow\mathrm\pi^+\mathrm\pi^- Cross Section between 600 and 900 MeV Using Initial State Radiation

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    We extract the e+eπ+πe^+e^-\rightarrow \pi^+\pi^- cross section in the energy range between 600 and 900 MeV, exploiting the method of initial state radiation. A data set with an integrated luminosity of 2.93 fb1^{-1} taken at a center-of-mass energy of 3.773 GeV with the BESIII detector at the BEPCII collider is used. The cross section is measured with a systematic uncertainty of 0.9%. We extract the pion form factor Fπ2|F_\pi|^2 as well as the contribution of the measured cross section to the leading order hadronic vacuum polarization contribution to (g2)μ(g-2)_\mu. We find this value to be aμππ,LO(600900  MeV)=(368.2±2.5stat±3.3sys)1010a_\mu^{\pi\pi,\rm LO}(600-900\;\rm MeV) = (368.2 \pm 2.5_{\rm stat} \pm 3.3_{\rm sys})\cdot 10^{-10}.Comment: 14 pages, 7 figures, accepted by PL
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