1,346 research outputs found
Hawking radiation by Kerr black holes and conformal symmetry
The exponential blueshift associated with the event horizon of a black hole
makes conformal symmetry play a fundamental role in accounting for its thermal
properties. Using a derivation based on two-point functions, we show that the
spectrum of thermal radiation of scalar particles by Kerr (and Schwarzschild)
black holes can be explicitly derived on the basis of a -dimensional
conformal symmetry arising in the wave equation near the horizon. This result
reinforces the recently conjectured relation between Kerr geometry and a
-dimensional conformal field theory.Comment: Version published in Phys. Rev. Let
Loop Quantum Gravity and the The Planck Regime of Cosmology
The very early universe provides the best arena we currently have to test
quantum gravity theories. The success of the inflationary paradigm in
accounting for the observed inhomogeneities in the cosmic microwave background
already illustrates this point to a certain extent because the paradigm is
based on quantum field theory on the curved cosmological space-times. However,
this analysis excludes the Planck era because the background space-time
satisfies Einstein's equations all the way back to the big bang singularity.
Using techniques from loop quantum gravity, the paradigm has now been extended
to a self-consistent theory from the Planck regime to the onset of inflation,
covering some 11 orders of magnitude in curvature. In addition, for a narrow
window of initial conditions, there are departures from the standard paradigm,
with novel effects, such as a modification of the consistency relation
involving the scalar and tensor power spectra and a new source for
non-Gaussianities. Thus, the genesis of the large scale structure of the
universe can be traced back to quantum gravity fluctuations \emph{in the Planck
regime}. This report provides a bird's eye view of these developments for the
general relativity community.Comment: 23 pages, 4 figures. Plenary talk at the Conference: Relativity and
Gravitation: 100 Years after Einstein in Prague. To appear in the Proceedings
to be published by Edition Open Access. Summarizes results that appeared in
journal articles [2-13
Electric-magnetic duality and renormalization in curved spacetimes
We point out that the duality symmetry of free electromagnetism does not hold in the quantum theory if an arbitrary classical gravitational background is present. The symmetry breaks in the process of renormalization, as also happens with conformal invariance. We show that a similar duality anomaly appears for a massless scalar field in 1 + 1 dimensions
Qualitative study in Loop Quantum Cosmology
This work contains a detailed qualitative analysis, in General Relativity and
in Loop Quantum Cosmology, of the dynamics in the associated phase space of a
scalar field minimally coupled with gravity, whose potential mimics the
dynamics of a perfect fluid with a linear Equation of State (EoS). Dealing with
the orbits (solutions) of the system, we will see that there are analytic ones,
which lead to the same dynamics as the perfect fluid, and our goal is to check
their stability, depending on the value of the EoS parameter, i.e., to show
whether the other orbits converge or diverge to these analytic solutions at
early and late times.Comment: 12 pages, 7 figures. Version accepted for publication in CQ
Enhanced local-type inflationary trispectrum from a non-vacuum initial state
We compute the primordial trispectrum for curvature perturbations produced
during cosmic inflation in models with standard kinetic terms, when the initial
quantum state is not necessarily the vacuum state. The presence of initial
perturbations enhances the trispectrum amplitude for configuration in which one
of the momenta, say , is much smaller than the others, . For those squeezed configurations the trispectrum acquires the
so-called local form, with a scale dependent amplitude that can get values of
order . This amplitude can be larger than the
prediction of the so-called Maldacena consistency relation by a factor ,
and can reach the sensitivity of forthcoming observations, even for
single-field inflationary models.Comment: 11 pages, 1 figure. References added, typos corrected, minor change
Numerical loop quantum cosmology: an overview
A brief review of various numerical techniques used in loop quantum cosmology
and results is presented. These include the way extensive numerical simulations
shed insights on the resolution of classical singularities, resulting in the
key prediction of the bounce at the Planck scale in different models, and the
numerical methods used to analyze the properties of the quantum difference
operator and the von Neumann stability issues. Using the quantization of a
massless scalar field in an isotropic spacetime as a template, an attempt is
made to highlight the complementarity of different methods to gain
understanding of the new physics emerging from the quantum theory. Open
directions which need to be explored with more refined numerical methods are
discussed.Comment: 33 Pages, 4 figures. Invited contribution to appear in Classical and
Quantum Gravity special issue on Non-Astrophysical Numerical Relativit
Loop Quantum Cosmology: A Status Report
The goal of this article is to provide an overview of the current state of
the art in loop quantum cosmology for three sets of audiences: young
researchers interested in entering this area; the quantum gravity community in
general; and, cosmologists who wish to apply loop quantum cosmology to probe
modifications in the standard paradigm of the early universe. An effort has
been made to streamline the material so that, as described at the end of
section I, each of these communities can read only the sections they are most
interested in, without a loss of continuity.Comment: 138 pages, 15 figures. Invited Topical Review, To appear in Classical
and Quantum Gravity. Typos corrected, clarifications and references adde
Stimulated creation of quanta during inflation and the observable universe
Inflation provides a natural mechanism to account for the origin of cosmic
structures. The generation of primordial inhomogeneities during inflation can
be understood via the spontaneous creation of quanta from the vacuum. We show
that when the corresponding {\it stimulated} creation of quanta is considered,
the characteristics of the state of the universe at the onset of inflation are
not diluted by the inflationary expansion and can be imprinted in the spectrum
of primordial inhomogeneities. The non-gaussianities (particularly in the
so-called squeezed configuration) in the cosmic microwave background and galaxy
distribution can then tell us about the state of the universe that existed at
the time when quantum field theory in curved spacetime first emerged as a
plausible effective theory.Comment: Awarded with the First Prize in the Gravity Research Foundation Essay
Competition 201
Quercetin prevents progression of disease in elastase/LPS-exposed mice by negatively regulating MMP expression
Abstract Background Chronic obstructive pulmonary disease (COPD) is characterized by chronic bronchitis, emphysema and irreversible airflow limitation. These changes are thought to be due to oxidative stress and an imbalance of proteases and antiproteases. Quercetin, a plant flavonoid, is a potent antioxidant and anti-inflammatory agent. We hypothesized that quercetin reduces lung inflammation and improves lung function in elastase/lipopolysaccharide (LPS)-exposed mice which show typical features of COPD, including airways inflammation, goblet cell metaplasia, and emphysema. Methods Mice treated with elastase and LPS once a week for 4 weeks were subsequently administered 0.5 mg of quercetin dihydrate or 50% propylene glycol (vehicle) by gavage for 10 days. Lungs were examined for elastance, oxidative stress, inflammation, and matrix metalloproteinase (MMP) activity. Effects of quercetin on MMP transcription and activity were examined in LPS-exposed murine macrophages. Results Quercetin-treated, elastase/LPS-exposed mice showed improved elastic recoil and decreased alveolar chord length compared to vehicle-treated controls. Quercetin-treated mice showed decreased levels of thiobarbituric acid reactive substances, a measure of lipid peroxidation caused by oxidative stress. Quercetin also reduced lung inflammation, goblet cell metaplasia, and mRNA expression of pro-inflammatory cytokines and muc5AC. Quercetin treatment decreased the expression and activity of MMP9 and MMP12 in vivo and in vitro, while increasing expression of the histone deacetylase Sirt-1 and suppressing MMP promoter H4 acetylation. Finally, co-treatment with the Sirt-1 inhibitor sirtinol blocked the effects of quercetin on the lung phenotype. Conclusions Quercetin prevents progression of emphysema in elastase/LPS-treated mice by reducing oxidative stress, lung inflammation and expression of MMP9 and MMP12.http://deepblue.lib.umich.edu/bitstream/2027.42/78260/1/1465-9921-11-131.xmlhttp://deepblue.lib.umich.edu/bitstream/2027.42/78260/2/1465-9921-11-131.pdfPeer Reviewe
Infrared effects in inflationary correlation functions
In this article, I briefly review the status of infrared effects which occur
when using inflationary models to calculate initial conditions for a subsequent
hot, dense plasma phase. Three types of divergence have been identified in the
literature: secular, "time-dependent" logarithms, which grow with time spent
outside the horizon; "box-cutoff" logarithms, which encode a dependence on the
infrared cutoff when calculating in a finite-sized box; and "quantum"
logarithms, which depend on the ratio of a scale characterizing new physics to
the scale of whatever process is under consideration, and whose interpretation
is the same as conventional field theory. I review the calculations in which
these divergences appear, and discuss the methods which have been developed to
deal with them.Comment: Invited review for focus section of Classical & Quantum Gravity on
nonlinear and nongaussian perturbation theory. Some improvements compared to
version which will appear in CQG, especially in Sec. 2.3. 30 pages +
references
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