Evaluación de un catalizador de Níquel-Ceria en la reacción de metanización de dióxido de carbono

En este trabajo se presenta el estudio de la reacción de metanización de CO₂ en fase gas empleando como catalizador Ni/CeO₂. Se sintetizó el soporte (CeO₂) por medio del método de plantilla dura y se agregó Ni al 5% en peso mediante la técnica de impregnación seca. Para la evaluación del catalizador se utilizó un reactor de lecho fijo. Se observó que la conversión aumenta con el paso del tiempo hasta alcanzar un máximo a los 30 minutos después del inicio de la reacción, incrementando el porcentaje de conversión a mayor temperatura alcanzando un máximo de 70% a 450 °C y una selectividad del 100% a metano.In this work we present the study of the gas phase methanation reaction of CO₂ using Ni/CeO₂ as catalyst. The support (CeO₂) was synthesized by the hard template method and Ni 5 wt% was added by the dry impregnation technique. For the evaluation of the catalyst a fixed bed reactor was employ. It was observed that the conversion rate increases over time until reach a maximum at 30 minutes after the beginning of the reaction. As well as the conversion rate increases with the time, this also happen whit the temperature. At 450 °C the conversion rate reaches the maximum of 70% with a selectivity of 100% to methane

Dispositivo para la administración de sustancias, estimulación y registro daser

Dispositivo para la administración de sustancias, estimulación y registro daser. Se trata de un dispositivo para uso neurofisiológico que permite la administración controlada de sustancias en nervio así como la monitorización de señales bioeléctricas en nervios espinales o craneales tanto in vivo como in vitro. El dispositivo consiste en una cámara de perfusión (1) del extremo terminal de nervios periféricos seccionados que permite la instilación continua con una solución salina de interés a la que se pueden añadir fármacos y/o colorantes con diversos objetivos experimentales a través de los conductos de entrada y salida (4,5). El dispositivo cumple además la función de permitir el registro del potencial de nervio provocado por la estimulación eléctrica en regiones de interés o de la actividad eléctrica espontánea de los axones presentes en el mismo mediante un par de electrodos (2,3). El conjunto de electrodos, cámara y conductos está termosellado (6) para la estanqueidad y estabilidad del dispositivo.Españ

Clinicopathological and Genomic Identification of Breast Cancers with No Impact on Mortality

Background. Implementing mammogram screening means that clinicians are seeing many breast cancers that will never develop metastases. The purpose of this study was to identify subgroups of breast cancer patients who did not present events related to long-term breast cancer mortality, taking into account diagnosis at breast screening, absence of palpability and axillary involvement, and genomic analysis with PAM50. Patients and Methods. To identify them, a retrospective observational study was carried out selecting patients without any palpable tumor and without axillary involvement, and a genomic analysis was performed with PAM50. Results. The probability of distant metastasis-free interval (DMFI) of 337 patients was 0.92 (95% CI, 0.90–0.93) at 20 years and 0.96 (95% CI, 0.92–1.00) in 95 patients (28%) with available PAM50 tests. In 22 (23.15%) luminal A tumors and in 9 (9.47%) luminal B tumors smaller than 1 cm, and in HER2 and basal type tumors, there were no metastatic events (20-year DMFI of 1.00). Conclusion. Patients with nonpalpable breast cancer found at screening with negative nodes are at very low risk. It is possible to identify subgroups without metastatic events by determining the intrinsic subtype and tumor size less than 1 cm. Therefore, de-escalation of treatment should be considered

Development of a prediction model for short-term remission of patients with Crohn’s disease treated with anti-TNF drugs

Therapy with anti-tumor necrosis factor (TNF) has dramatically changed the natural history of Crohn’s disease (CD). However, these drugs are not without adverse events, and up to 40% of patients could lose efficacy in the long term. We aimed to identify reliable markers of response to anti-TNF drugs in patients with CD. A consecutive cohort of 113 anti-TNF naive patients with CD was stratified according to clinical response as short-term remission (STR) or non-STR (NSTR) at 12 weeks of treatment. We compared the protein expression profiles of plasma samples in a subset of patients from both groups prior to anti-TNF therapy by SWATH proteomics. We identified 18 differentially expressed proteins (p ≤ 0.01, fold change ≥ 2.4) involved in the organization of the cytoskeleton and cell junction, hemostasis/platelet function, carbohydrate metabolism, and immune response as candidate biomarkers of STR. Among them, vinculin was one of the most deregulated proteins (p < 0.001), whose differential expression was confirmed by ELISA (p = 0.054). In the multivariate analysis, plasma vinculin levels along with basal CD Activity Index, corticosteroids induction, and bowel resection were factors predicting NSTR

Usos del e‐learning en las Universidades Andaluzas: estado de la situación y análisis de buenas prácticas. (Resumen ejecutivo).

Secretaría General de Universidades, Investigación y Tecnología P07-SE-J.0267

Usos del e-learning en las Universidades Andaluzas: Estado de la situación y análisis de buenas prácticas. (Versión completa)

Secretaría General de Universidades, Investigación y Tecnología P07-SE-J.0267

Insularity determines nestling sex ratio variation in Egyptian vulture populations

Variation in offspring sex ratio, particularly in birds, has been frequently studied over the last century, although seldom using long-term monitoring data. In raptors, the cost of raising males and females is not equal, and several variables have been found to have significant effects on sex ratio, including food availability, parental age, and hatching order. Sex ratio differences between island populations and their mainland counterparts have been poorly documented, despite broad scientific literature on the island syndrome reporting substantial differences in population demography and ecology. Here, we assessed individual and environmental factors potentially affecting the secondary sex ratio of the long-lived Egyptian vulture Neophron percnopterus. We used data collected from Spanish mainland and island populations over a ca. 30-year period (1995-2021) to assess the effects of insularity, parental age, breeding phenology, brood size, hatching order, type of breeding unit (pairs vs. trios), and spatial and temporal variability on offspring sex ratio. No sex bias was found at the population level, but two opposite trends were observed between mainland and island populations consistent with the island syndrome. Offspring sex ratio was nonsignificantly female-biased in mainland Spain (0.47, n = 1112) but significantly male-biased in the Canary Islands (0.55, n = 499), where a male-biased mortality among immatures could be compensating for offspring biases and maintaining a paired adult sex ratio. Temporal and spatial variation in food availability might also have some influence on sex ratio, although the difficulties in quantifying them preclude us from determining the magnitude of such influence. This study shows that insularity influences the offspring sex ratio of the Egyptian vulture through several processes that can affect island and mainland populations differentially. Our research contributes to improving our understanding of sex allocation theory by investigating whether sex ratio deviations from parity are possible as a response to changing environments comprised by multiple and complexly interrelated factors.Research was funded and supported by the Spanish Ministry of Economy, Industry and Competitiveness (CGL2007-61395, CGL2010-15726, CGL2013-42451-P), the Spanish Ministry of Science and Innovation (PID2019-109685GB-I00, RTI2018-099609-B-C21), Junta de Andalucía (P18-RT-1321, EMERIGIA 2021.1524, FEDER 2021_1073), Diputación General de Aragón, Gobierno de las Islas Baleares, Gobierno de Canarias, Cabildo Insular de Fuerteventura, Junta de Castilla y León, and Comunidad de Bardenas Reales de Navarra. G.G.L. was supported by a FPU fellowship of the Spanish Ministry of Science, Innovation and Universities (FPU19/06511). A.S.A. was supported by a Ramón y Cajal fellowship of the Spanish Ministry of Science (RYC-2017-22796). E.A. was supported by La Caixa-Severo Ochoa International PhD Program 2015; Generalitat Valenciana and European Social Fund (APOSTD/2021), and Spanish Ministry of Science, Innovation and Universities Contracts (FJC2021-047885-I). M.G.A. was supported by a contract from “Programa de FPU del Ministerio de Educación, Cultura y Deporte” (FPU13/05429). A.C.A. was supported by EMERGIA Program from Junta de Andalucía. IMEDEA is an accredited “Maria de Maeztu Excellence Unit” (ref. CEX2021-001198/funded by MCIN/AEI/10.13039/501100011033).With funding from the Spanish government through the "Severo Ochoa Centre of Excellence" accreditation (CEX2021-001198).Peer reviewe

A qué sabe el norte?

Libro que compila saberes de las recetas ancestrales y sabores tradicionales de la gastronomía Nortesantandereana, recopila 3 rutas de turismo gastronómico que conjuga 30 municipios de norte de santander y más de 300 tipos de sopas, platos fuertes y postres.Book that compiles knowledge of ancestral recipes and traditional flavors of gastronomy Nortesantandereana, compiles 3 routes of gastronomic tourism that brings together 30 municipalities of northern Santander and more than 300 types of soups, main dishes and desserts.Ruta del durazno y el agua -- Ruta del oro negro -- Ruta del río y la gran convención -- Las mujeres de la independencia -- Honrando a nuestros portadores del saber -- A qué sabe el norte-recetarioPrimera ediciónna230 página

Ética Profesional y Responsabilidad Social Universitaria

este libro compila reflexiones y experiencias en responsabilidad social y ética profesional desde instituciones de Educación Superior. La responsabilidad social universitaria, como ámbito de investigación y de desarrollo conceptual y metodológico es transversal a las universidades, tanto desde el punto de vista organizacional, como desde el misional e investigativo. Quienes impulsen la responsabilidad social, requieren de ética profesional, que debe ser la clave para la construcción de principios que guíen a empresarios, políticos, gestores sociales, investigadores, entre otros, para lograr consensuar el a veces difícil equilibrio entre el bien común y el desarrollo personal

Challenge B: Human sciences in transition scenarios

Coordinators: Josep Martí Pérez (IMF, CSIC), Idoia Murga Castro (IH, CSIC).This challenge is formulated in terms of “humanities in transition,” that is, their approach and articulation in the face of the changes they must undergo to achieve the social weight that, due to their intrinsic relevance, should correspond to them. Faced with these situations that would demand a reinforcement in research and dissemination in diverse aspects of the humanities, from multiple perspectives, paradoxically an adverse panorama is drawn for the development and dissemination of humanistic knowledge, which concerns different factors. Some are related to the consideration of the area of knowledge itself, its organization within the scientific system, the questioning of its own limits, and the interaction with another knowledge. Considering current transition scenarios does not mean having to abandon old objectives, but it adds to the work conducted new objects of study closely related to current reality, such as: the informational revolution; the relations with the ecosystem and the environmental crisis; globalization; the intensification of human mobility and migration flows; the growing economic and social inequality; the frictions derived from the articulation of collective identities; the decolonization of discourses; demographic dynamics; integration of technological advances; and viability and support for alternative models of society.Peer reviewe