Constraints Militating Against the Implementation of Production/Service Work In Technical Colleges in North Central Nigeria

Skill acquisition is a critical component of any vocational technical training program. When this component is missing or falls below expectation, it tends to defeat the objectives of the program. In Nigeria, many skill-oriented schools experience great challenges in trying to provide for the necessary facilities required for effective technical training of those enrolled in its program because of paucity of funds. The result often times, is that students are likely to graduate from the programs without adequate employability skills for meaningful productive/service work after leaving school. In realization of this predicament, the Federal Government of Nigeria directed all technological institutions to establish what is called Production/Service Work (PSW) into its curriculum. This is done in the event that there is shortfall in the supply of training facilities to school workshops by proprietors, schools can receive jobs from within or outside the school  which would provide them the opportunity to acquire hands-on experience that would  equip them with requisite skills for post- graduation work. As laudable as this innovation appears to be many schools in the North Central Nigeria are yet to implement the innovation in their schools and even where  they have, they are not viable and do not seem to meet the objectives set out for them. The present study, therefore, sought to unravel the challenges (external and internal) constraining the effective implementation of PSW in technical colleges. When this is done, it might provide a framework for deliberate action towards ameliorating the challenges that are faced by the schools. Keywords: External constraints, internal constraints, trade, production/service work, skill

Effect of Corruption on Corporate Governance in Selected Area Offices of Deposit Money Banks in Enugu State, Nigeria

The study seeks to examine the effect of corruption on corporate governance in selected area offices of deposit money banks in Enugu State, Nigeria. The specific objectives were to; (i) determine the extent to which bribery affects the board of directors\u27 functions, (ii) ascertain the extent to which fraud affects the managers\u27 accountability, and (iii) identify the nature of the relationship existing between money laundering and shareholders\u27 investment in selected area offices of deposit money banks in Enugu State, Nigeria. The study adopted a descriptive survey design. The population of the study was 1197, which comprised the senior and junior staff members of the five selected banks (United Bank for Africa Plc, First Bank of Nigeria Plc, Access Bank Plc, Fidelity Bank Plc, and Skye Bank Plc.). The sample size of 316 was obtained from the population using Freud and William\u27s formula at 5% error tolerance and 95% level of confidence. Data collection was done via a questionnaire and an oral interview guide. Simple Linear Regression Analysis and Pearson Product Moment Correlation were used for data analysis

Treatment Outcomes in Patients Receiving Combination Antiretroviral Therapy in Central Hospital, Benin City, Nigeria

Purpose: This study investigated mortality rate, early CD4 responses, pattern of ARVs substitutions and medication adherence of HIV-infected patients on first-line triple combination antiretroviral therapy (ART) in Central Hospital, Benin City, Nigeria. Methods: A retrospective assessment of 196 HIV-infected patients on first-line combination ART regimens was performed following 18 months of therapy. Medication adherence assessment of a 69- patient follow-up target group was based on a study-specific questionnaire. Paired sample t-test and simple linear correlation were used to test the association of the CD4-cell counts at different time intervals. Kaplan-Meier model was used to assess survival functions while log-rank test was applied to assess statistical difference at 95 % confidence interval (CI). Mean age of participants was 33.6 years (95 % CI, 32.1 - 35.2; 67.9 % were females. Results: At ART initiation, 27.0 % were at WHO clinical stage II, 47.0 % at stage III. Mortality rate (N = 196) was 20.3 deaths per 100 patient-months; 31.6 % occurred in < 30 days while 52.6 % occurred post-120 days of treatment. The mean CD4-cell count (cells/mm3) at ART initiation was 179.2 which increased to 328.5 at 3 months, 325.6 at 6 months, 357.4 at 12 months, and 366.7 at 18 months, (p < 0.01). Patients started on stavudine-based or efavirenz-based regimens were considerably more likely to have that drug substituted, compared to patients started on zidovudine-based or nevirapine-based regimens. The level of adherence reported after 18 months on ART was 73.8 %. Conclusion: In this setting, patients receiving ART showed significant improvements in CD4-cell status but adherence level was relatively poor. Patients were more stable on zidovudine-based or nevirapinebased regimens than on stavudine-based or efavirenz-based regimens. Early mortality rate was high, indicating a need for early interventions.Keywords: Antiretroviral therapy; HIV/AIDS; Mortality; Therapy outcomes, Nigeri

Endothelial cells derived from patients' induced pluripotent stem cells for sustained factor VIII delivery and the treatment of hemophilia A.

Hemophilia A (HA) is a bleeding disorder characterized by spontaneous and prolonged hemorrhage. The disease is caused by mutations in the coagulation factor 8 gene (F8) leading to factor VIII (FVIII) deficiency. Since FVIII is primarily produced in endothelial cells (ECs) in a non-diseased human being, ECs hold great potential for development as a cell therapy for HA. We showed that HA patient-specific induced pluripotent stem cells (HA-iPSCs) could provide a renewable supply of ECs. The HA-iPSC-derived ECs were transduced with lentiviral vectors to stably express the functional B domain deleted F8 gene, the luciferase gene, and the enhanced green fluorescent protein gene (GFP). When transplanted intramuscularly into neonatal and adult immune deficient mice, the HA-iPSC-derived ECs were retained in the animals for at least 10-16 weeks and maintained their expression of FVIII, GFP, and the endothelial marker CD31, as demonstrated by bioluminescence imaging and immunostaining, respectively. When transplanted into HA mice, these transduced HA-iPSC-derived ECs significantly reduced blood loss in a tail-clip bleeding test and produced therapeutic plasma levels (11.2%-369.2%) of FVIII. Thus, our studies provide proof-of-concept that HA-iPSC-derived ECs can serve as a factory to deliver FVIII for the treatment of HA not only in adults but also in newborns

Cross-Border Transmission of Interest Rate Shocks: A VAR Analysis of the Nigerian Economy

This paper examined if interest rate shocks from the U.S are transmitted to Nigeria. For this purpose, we collected data on four Nigerian variables (real GDP, CPI, exchange rate and interest rate) and two foreign variables (U.S FFR and the world CPI) for the period 1983-2011. The impulse response analysis of our VAR model shows that Nigerian variables respond insignificantly to shocks from foreign variables. We therefore concluded that shocks in Nigeria are basically home-made.  We recommended that monetary authorities in Nigeria should base their policy making on domestic shocks, as considering external factors might mislead them. Keywords: Interest rate shock, International transmission, Nigeria, U.S.A., VAR

The role of the academic library in providing outreach services to prison inmates by means of mobile tools and technologies

This study investigated the role of academic library in providing outreach services to prison inmates by means of mobile tools and technologies in Nsukka prison library. The research adopted qualitative inquiry approach for the processes and procedures of the research. It was guided by five objectives which includes – the outreach services provided by the academic library to the prison inmates by means of mobile tools and technologies, the mobile tools and technologies used for the provision of outreach services to the prison inmates by means of mobile tools and technologies, the benefits of outreach services as provided by prison inmates by means of mobile tools and technologies, problems encountered in the provision of outreach services to prison inmates by means of mobile tools and technologies and strategies for enhancing the provision of outreach services to prison inmates by means of mobile tools and technologies. Data obtained from the questionnaire was analysed using mean and percentages while the ones obtained from focus group discussion was analysed in prose narrative. Among other things, the findings revealed that outreach services are provided to the prison inmates by the academic library. Other findings from the research revealed that mobile tools and technologies are being introduced to the delivery of outreach services in the prison library, the prison inmates support the delivery of outreach services to them by means of mobile tools and technologies, the prsion authority/administration permits the academic librarian’s provision of outreach services to the prison inmates. However, inadequate fund, personnel and mobile tools forms the major part of the problems encountered in the delivery of outreach servises to the inmates. Based on the findings, it was recommended among other things that there should be provision of adequate mobile tools and technologies for the delivery of outreach services, there should be integration of outreach services with other educational programmes, there should be training and retraining of both the prison inmates and the academic library on the use of mobile devices among others. More importantly, there should be provision of a functional prison library to accommodate resources – tool, technologies, personnel for the provision of library services to the inmates

Does Multilateralism Crowd Out Intra-Group Trade? Evidence From Some Developing Regions

The literature is ambiguous on the nature of the relationship between multilateral trade negotiations and growth of intra-group trade. However, both the WTO and proponents ofliberalization maintain that the relationship is positive and that the WTO supports regional bodies and intra-group trade. But does evidence support this? It is possible that the WTO supports regional bonding, while its existence discourages growth of actual trade and development of institutions within regions. Our findings seem to support this view, particularly for southern countries as shown by trends in intra-group trade captured in this work

Impact of Talent Management Strategies on Organizational Performance in Selected Deposit Money Banks in Lagos State, Nigeria

This study critically examined the Impact of Talent Management Strategies on Organizational Performance in Selected Deposit Money Banks (DMB) in Lagos State, Nigeria. Specifically, the study sought to; (i) determine the extent succession planning relates to sustainability; (ii) ascertain to what extent human capital development impacts on innovative capabilities of employees; and, (iii) examine the degree compensation impacts on employee engagement, in selected DMBs under study. The study adopted the survey design. The population of the study was 3126 comprising management and junior staff drawn from the selected DMBs in Lagos state, Nigeria. These include First Bank of Nigeria Plc, United Bank for Africa Plc, Zenith Bank Plc, Access Bank Plc, and Ecobank Plc. The sample size of 359 was obtained from the population using Bill Godden\u27s formula at 5% error margin and 90% level of confidence. Data were collected using the questionnaire research instrument and interview guide which was designed in a 5-point Likert Scale and was manually administered to the respondents. The validity of the instrument was measured using content validity, and this was done by three management experts from both the industry and the academia

Learning Style Preference: Impact on Academic Performance of Preclinical Medical Students, a Nigerian Survey

Background: Understanding the differences in learning styles among medical students and their impact on the learning processes may enhance better learning and knowledge acquisition that is necessary for improving learning outcomes. This study aimed at the determination of the learning style preferences of the University of Nigeria preclinical medical students and the impact they have on their academic performance. Materials and Methods: The study involved 158 third-year medical students (102 males and 56 females). Each student completed the VARK questionnaire (Version 7) comprising 16 questions that identified four different learning style preferences, namely V – visual, A – aural, R – read–write, and K – kinesthetic. The academic performance of the students was obtained from the results of their second MBBS professional examination. Analysis of data was done using Statistical Package for the Social sciences (SPSS) version 21; the percentages and charts of distribution for each VARK component were determined. The presence/absence of significant interactions between academic performance and learning style preferences was determined using Chi-square test. Results: The results showed that 30.4% of the students were unimodal (V-2.5%, A-7%, R-17.1% and K-3.8%), while 69.6% were multimodal in learning. With respect to gender, the males (70.6%) and females (67.9%) preferred multimodal learning, and both genders showed similar patterns in their preferences (read–write, followed by aural, kinesthetic, and visual). Visual learners exhibited the highest scores among unimodal learners, followed by kinesthetic, aural, and read–write learners, although the mean performance of multimodal learners (65%) was higher than those of unimodal learners (54%) (P &lt; 0.001). Conclusion: A blend of V‑A‑R‑K instructional techniques would benefit most students. Students who are strongly unimodal in learning need to be specifically targeted with their unique learning style. Keywords: Anatomy, Nigeria, learning style. academic performance, preclinical students, V-A-R-