Flux creep in Bi2Sr2Ca1Cu2O(8+x) single crystals

Dissipative effects were investigated in Bi2Sr2Ca1Cu2O(8+x) single crystals by critical current and magnetic relaxation measurements. Activation energies for the flux motion were determined from the temperature dependence of the critical current and from the time decay of the zero field cooled and the remanent magnetization. The effective activation energy was found to increase with temperature, in agreement with the existence of a distribution of activation energies (E sub o 20 meV at 4.2 K for H + 10 kOe applied parallel to the c-axis.)

Flux creep in Bi2Sr2CaCu2O8(sub +x) single crystals

The results of a magnetic study on a Bi2Sr2CaCu2O(8+x) single crystal are reported. Low field susceptibility (dc and ac), magnetization cycles and time dependent measurements were performed. With increasing the temperature the irreversible regime of the magnetization cycles is rapidly restricted to low fields, showing that the critical current J(sub c) becomes strongly field dependent well below T(sub c). At 2.4 K the critical current in zero field, determined from the remanent magnetization by using the Bean formula for the critical state, is J(sub c) = 2 10(exp 5) A/sq cm. The temperature dependence of J(sub c) is satisfactorily described by the phenomenological law J(sub c) = J(sub c) (0) (1 - T/T(sub c) (sup n), with n = 8. The time decay of the zero field cooled magnetization and of the remanent magnetization was studied at different temperatures for different magnetic fields. The time decay was found to be logarithmic in both cases, at least at low temperatures. At T = 4.2 K for a field of 10 kOe applied parallel to the c axis, the average pinning energy, determined by using the flux creep model, is U(sub o) = 0.010 eV

Noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease in the emergency department: early predictors of in-hospital outcome

The applications of early non-invasive ventilation (NIV) are nowadays expanding in the Emergency Department (ED) for the treatment of different types and etiologies of acute respiratory failure (ARF) Emergency physicians (EP) often face the challenge of predicting short-term outcomes for patients with ARF in the E

Investigation of hypersonic flow in the vki h3 wind tunnel: From facility characterization to boundary-layer interaction over low-temperature ablators

This work deals with the characterization, in terms of operating conditions, of the H3 hypersonic wind tunnel of the von Karman Institute for Fluid Dynamics (VKI), thus providing a detailed and structured benchmark for the evaluation of testing capabilities in hypersonic wind tunnels, and with the experimental study of the interaction between the boundary layer and the ablation process of low temperature ablative materials. The flow characteristics of the test section of the H3 WT have been assessed by using a pitot rake, for a wider range of operating conditions with respect to previous calibrations. A CFD analysis of the diffuser-ejector system has been carried out to assess its performance, and an experimental test campaign has been performed in order to validate the CFD analyses and completely characterize the facility operating conditions. Finally, a series of experiments with models of increasing size and different shapes has been carried out to determine the blockage effect in the tunnel test section. The H3 WT is then employed to study the boundary layer interaction with the ablative process on low temperature ablative models. These models have been built after having appropriately designed the sintering system. The Planar Laser Induced Fluorescence method has been applied to visualize the flow behavior: a laminar-turbulent transition due to the ablation process has been observed, together with the main flow structures

Methodology framework for prioritisation of renewable energy sources in port areas

Ports play a crucial role in increasing the decarbonisation of urban environments to mitigate the environmental impacts of maritime transport and promote sustainable intermodal mobility. Various efforts have been made to increase energy self-sufficiency using renewable energy sources (RESs) in different ports worldwide. However, the ports played an essential role in the pollution process of the nearest cities due to the short distance and merging with urban areas. In this case, solar and wind were measured using the Modern-Era Retrospective analysis for Research and Applications, Version 2 (MERRA-2) data of four Lazio province ports. Each RES was evaluated using 10 years of monthly data for mapping and 1 year of hourly data for potential assessment and energy converters installation. Furthermore, the time series method has been considered to design and develop better management of RESs for decision making monitoring the energy needs of ports. This time series method has been applied to the generated energy source based on various parameters of the RESs used in port

Low energy conversion electron detection in superfluid He3 at ultra-low temperature

We report on the first results of the MACHe3 (MAtrix of Cells of Helium 3) prototype experiment concerning the measurement of low energy conversion electrons at ultra-low temperature. For the first time, the feasibility of the detection of low energy electrons is demonstrated in superfluid He3-B cooled down to 100 microK. Low energy electrons at 7.3 keV coming from the K shell conversion of the 14.4 keV nuclear transition of a low activity Co57 source are detected, opening the possibility to use a He3-based detector for the detection of Weakly Interacting Massive Particles (WIMPs) which are expected to release an amount of energy higher-bounded by 5.6 keV.Comment: 8 pages, 3 figures, to appear in NIM

A practical algorithmic approach to mature aggressive B cell lymphoma diagnosis in the double/triple hit era. Selecting cases, matching clinical benefit. A position paper from the Italian Group of Haematopathology (G.I.E.)

An accurate diagnosis of clinically distinct subgroups of aggressive mature B cell lymphomas is crucial for the choice of proper treatment. Presently, precise recognition of these disorders relies on the combination of morphological, immunophenotypical, and cytogenetic/molecular features. The diagnostic workup in such situations implies the application of costly and time-consuming analyses, which are not always required, since an intensified treatment option is reasonably reserved to fit patients. The Italian Group of Haematopathology proposes herein a practical algorithm for the diagnosis of aggressive mature B cell lymphomas based on a stepwise approach, aimed to select cases deserving molecular analysis, in order to optimize time and resources still assuring the optimal management for any patient

Performance of a Large Area Avalanche Photodiode in a Liquid Xenon Ionization and Scintillation Chamber

Scintillation light produced in liquid xenon (LXe) by alpha particles, electrons and gamma-rays was detected with a large area avalanche photodiode (LAAPD) immersed in the liquid. The alpha scintillation yield was measured as a function of applied electric field. We estimate the quantum efficiency of the LAAPD to be 45%. The best energy resolution from the light measurement at zero electric field is 7.5%(sigma) for 976 keV internal conversion electrons from Bi-207 and 2.6%(sigma) for 5.5 MeV alpha particles from Am-241. The detector used for these measurements was also operated as a gridded ionization chamber to measure the charge yield. We confirm that using a LAAPD in LXe does not introduce impurities which inhibit the drifting of free electrons.Comment: 13 pages, 8 figure

An analysis method for time ordered data processing of Dark Matter experiments

The analysis of the time ordered data of Dark Matter experiments is becoming more and more challenging with the increase of sensitivity in the ongoing and forthcoming projects. Combined with the well-known level of background events, this leads to a rather high level of pile-up in the data. Ionization, scintillation as well as bolometric signals present common features in their acquisition timeline: low frequency baselines, random gaussian noise, parasitic noise and signal characterized by well-defined peaks. In particular, in the case of long-lasting signals such as bolometric ones, the pile-up of events may lead to an inaccurate reconstruction of the physical signal (misidentification as well as fake events). We present a general method to detect and extract signals in noisy data with a high pile-up rate and qe show that events from few keV to hundreds of keV can be reconstructed in time ordered data presenting a high pile-up rate. This method is based on an iterative detection and fitting procedure combined with prior wavelet-based denoising of the data and baseline subtraction. {We have tested this method on simulated data of the MACHe3 prototype experiment and shown that the iterative fitting procedure allows us to recover the lowest energy events, of the order of a few keV, in the presence of background signals from a few to hundreds of keV. Finally we applied this method to the recent MACHe3 data to successfully measure the spectrum of conversion electrons from Co57 source and also the spectrum of the background cosmic muons

Mechanism of cell death induced by spermine and amine oxidase in mouse melanoma cells

Polyamines such as spermine, spermidine and putrescine are necessary for cell proliferation and are detected at higher concentrations in most tumor tissues, compared to normal tissues. The amine oxidase enzymes can generate cytotoxic products such as hydrogen peroxide and aldehydes from these polyamines. This study investigates the mechanisms of cell death in B16-F0 mouse melanoma tumor cells exposed to bovine serum amine oxidase and exogenous spermine. The bovine serum amine oxidase/spermine enzymatic system induced inhibition of cell proliferation in B16-F0 melanoma cells and cell death by both apoptotic and necrotic processes. Bovine serum amine oxidase or spermine, alone, did not induce cytotoxicity or cell death by apoptosis, indicating that the enzymatic reaction products were responsible. Catalase and NAD-dependent aldehyde dehydrogenase, inhibitors of hydrogen peroxide and aldehydes, respectively, decreased cell death by apoptosis and necrosis. This further confirms that the cytotoxic products are responsible for causing cell death. Use of inhibitors of different caspases showed that melanoma cells were sensitive to processes involving caspase-3 and -9, but were insensitive to caspase-6. Bovine serum amine oxidase in the presence of spermine could be useful as a promising new tool for anticancer treatment by the selective generation of toxic compounds from polyamines in tumors