1,040 research outputs found

    The Influence of Alcohol Warning Labels on Consumers’ Choices of Wine and Beer

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    This study aims to analyse the influence of alternative formats of health warnings on French and Italian Millennial consumers’ choices of beer and wine. Two Discrete Choice Experiments were built for wine and beer and two Latent Class choice models were applied in order to verify the existence of different consumer profiles. Results show that young consumers’ choices for wine and beer are influenced by framing, design and visibility of warnings. In both countries, the acceptance of warnings is higher for beer than for wine and in both cases consumers show higher utility for a logo on the front label: on the neck with a neutral message in the case of beer; on the front, without a message for wine. Latent Class choice models highlight the existence of different consumers’ groups with different levels of warning influencing their choices. In order to apply policies conducting to health benefits, our results suggest the need to focus on young individuals to communicate the risks of alcohol abuse through targeted messages and, more generally, to make them aware of the potential negative effects of excessive consumption of both wine and beer

    Indium selenide: An insight into electronic band structure and surface excitations

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    We have investigated the electronic response of single crystals of indium selenide by means of angle-resolved photoemission spectroscopy, electron energy loss spectroscopy and density functional theory. The loss spectrum of indium selenide shows the direct free exciton at similar to 1.3 eV and several other peaks, which do not exhibit dispersion with the momentum. The joint analysis of the experimental band structure and the density of states indicates that spectral features in the loss function are strictly related to single-particle transitions. These excitations cannot be considered as fully coherent plasmons and they are damped even in the optical limit, i.e. for small momenta. The comparison of the calculated symmetry-projected density of states with electron energy loss spectra enables the assignment of the spectral features to transitions between specific electronic states. Furthermore, the effects of ambient gases on the band structure and on the loss function have been probed

    Ultrasonographic honeycomb pattern of the spleen in cats: correlation with pathological diagnosis in 33 cases

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    Objectives: The aim of this study was to evaluate the relationship between the ultra sonographic (US) diffuse honeycomb pattern (HCP) of the spleen and a pathological diagnosis in cats, and to assess the influence of transducer type on HCP visualisation. Methods: Abdominal ultrasounds of cats with an HCP were reviewed and splenic size, shape, margination, other parenchymal alterations and splenic hilar lymphadenopathy were recorded. When applicable, images acquired with high-frequency linear and curvilinear transducers were compared to determine if an HCP was more frequently demonstrated on high-resolution images. A retrospective review of the corresponding splenic cyto histopathological samples was also performed. Results: Thirty-three cats met the inclusion criteria. Five cases were diagnosed by histology and 28 by cytology, confirmed by PCR for antigen receptor rearrangements (PARR) in uncertain cases. There were 15 cases of lymphoid hyperplasia, eight cases of lymphoma (four B cell, three T cell and one large granular lymphocytes), six cats with splenitis, three with extramedullary haematopoiesis and one with histiocytic sarcoma. The prevalence of lymphoma in cats with an HCP of the spleen was 24%. Splenomegaly was the most frequent US feature associated with an HCP and was observed in all lymphoma cases. In the images obtained from both high-frequency linear and micro-convex transducers the visualisation of an HCP was enabled in all cases (24/24) and in 62.5% (15/24), respectively. Conclusions and relevance: Based on our findings, an US HCP of the spleen in cats can be associated with benign and malignant disorders and is infrequently associated with lymphoma in comparison with dogs. Cytological or histological examination, possibly supplemented by PARR, should always be performed for diagnostic support. Use of high-frequency linear transducers is recommended to properly recognise an HCP or subtle changes in splenic parenchyma

    A DVD-MoS2/Ag2S/Ag nanocomposite thiol-conjugated with porphyrins for an enhanced light-mediated hydrogen evolution reaction

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    We have recently demonstrated in a previous work an appreciable photoelectrocatalytic (PEC) behavior towards hydrogen evolution reaction (HER) of a MoS2/Ag2S/Ag nanocomposite electrochemically deposited on a commercial writable Digital Versatile Disc (DVD), consisting therefore on an interesting strategy to convert a common waster product in an added-value material. Herein, we present the conjugation of this MoS2/Ag2S/Ag-DVD nanocomposite with thiol-terminated tetraphenylporphyrins, taking advantage of the grafting of thiol groups through covalent S-S bridges, for integrating the well-known porphyrins photoactivity into the nanocomposite. Moreover, we employ two thiol-terminated porphyrins with different hydrophilicity, demonstrating that they either suppress or improve the PEC-HER performance of the overall hybrid, as a function of the molecule polarity, sustaining the concept of a local proton relay. Actually, the active polar porphyrin—MoS2/Ag2S/Ag-DVD hybrid material presented, when illuminated, a better HER performance, compared to the pristine nanocomposite, since the porphyrin may inject photoelectrons in the conduction band of the semiconductors at the formed heterojunction, presenting also a stable operational behavior during overnight chopped light chronoamperometric measurement, thanks to the robust bond created

    Uso e (abuso) di prassi di ricerca problematiche in psicologia

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    Keywords: Questionable Research Practices; Research Credibility; Scientific Transparency; Italian Research Psychology. Le prassi di ricerca problematiche sono prassi metodologiche che aumentano la probabilità di fornire evidenze a supporto di un'ipotesi quando, in realtà, l'evidenza potrebbe essere spuria, introducendo così delle distorsioni nella letteratura scientifica. I bassi tassi di riproducibilità nella letteratura psicologica, riscontrati negli studi di replica, possono essere attribuiti (almeno in parte) all'uso di queste prassi di ricerca. Quali sono le cause della messa in atto delle prassi di ricerca problematiche e la prevalenza del loro utilizzo? John, Loewenstein e Prelec (2012) hanno condotto uno studio andando ad indagare la messa in atto di pratiche di ricerca problematiche con un questionario rivolto a psicologi accademici afferenti ad università statunitensi. I risultati indicano sorprendentemente la presenza di una diffusa messa in atto delle prassi di ricerca problematiche. Uno studio di replica è stato condotto con gli psicologi italiani iscritti all'Associazione Italiana Psicologi. I risultati molto simili ottenuti nei due studi (Stati Uniti e Italia) indicano che le prassi sono ampiamente adottate in ambedue le comunità di ricerca. La somiglianza dei risultati negli Stati Uniti, in Italia e i risultati ottenuti in uno studio simile in Germania, suggerisce che la messa in atto di queste prassi riguarda un fenomeno internazionale, probabilmente dovuto a caratteristiche sistemiche dei processi di ricerca e di pubblicazione

    Novel sequence variants of viral hexon and fibre genes in two dogs with canine adenovirus type 1-associated disease

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    There is little information on sequence variation of canine adenovirus type 1 (CAdV-1), the aetiological agent of infectious canine hepatitis (ICH). This study reports hexon and fibre gene sequence variants of CAdV-1 in a dog with systemic ICH and a dog with the ocular form of the disease (\ue2\u80\u98blue eye\ue2\u80\u99) in Northern Italy in 2013. One of the sequence variants matched a CAdV-1 fox sequence previously detected in Italy

    Oxidized multiwalled nanotubes as efficient carbocatalyst for the general synthesis of azines

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    The carbocatalytic synthesis of azines (N-N linked diimines) by mild-oxidized multiwalled carbon nanotubes catalyst (oxMWNT) is presented. The material, just with a 5 %wt. loading, is able to carry out a smooth room-temperature metal-free condensation of aldehydes and hydrazine, without external additives, to obtain a wide library of symmetric and also asymmetric azines in excellent yields, even in gram scale, with an excellent selectivity for aromatic substrates. This methodology allows the synthesis of azines with application in nonlinear optics, and the organic materials and biological active compounds crafting. oxMWNT catalysed the reaction in just 3 h with full recyclability upon the recovery of the catalyst. In addition, due to the inherent oxMWNT oxidative capacity in the presence of nitric acid, we have also developed the one-pot synthesis of azines starting from alcoholsFinancial support was provided by the European Research Council (ERC-CoG, Contract Number: 647550, ERC-PoC, Contract No. 861930), the Spanish Government (RTI2018-095038-B-I00), the ‘Comunidad de Madrid’ and European Structural Funds (S2018/NMT-4367) and proyectos sinérgicos I+D (Y2020/NMT6469). M.B. wishes to thank the Spanish Government for a Juan de la Cierva contract (IJC2019-042157-I

    Individual differences and creative ideation: neuromodulatory signatures of mindset and response inhibition

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    This study addresses the modulatory role of individual mindset in explaining the relationship between response inhibition (RI) and divergent thinking (DT) using transcranial direct current stimulation (tDCS). Forty undergraduate students (22 male and 18 female), aged between 18 and 23 years (average age = 19 years, SD = 1.48), were recruited. Participants received either anodal tDCS of the right IFG coupled with cathodal tDCS of the left IFG (R + L−; N = 19) or the opposite coupling (R−L+; N = 21). We tested DT performance using the alternative uses task (AUT), measuring participants’ fluency, originality, and flexibility in the response production, as well as participants’ mindsets. Furthermore, we applied a go-no-go task to examine the role of RI before and after stimulating the inferior frontal gyrus (IFG) using tDCS. The results showed that the mindset levels acted as moderators on stimulation conditions and enhanced RI on AUT fluency and flexibility but not originality. Intriguingly, growth mindsets have opposite moderating effects on the change in DT, resulting from the tDCS stimulation of the left and the right IFG, with reduced fluency but enhanced flexibility. Our findings imply that understanding neural modulatory signatures of ideational processes with tDCS strongly benefits from evaluating cognitive status and control functions

    Epigenome-wide association study reveals decreased average methylation levels years before breast cancer diagnosis

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    Interest in the potential of DNA methylation in peripheral blood as a biomarker of cancer risk is increasing. We aimed to assess whether epigenome-wide DNA methylation measured in peripheral blood samples obtained before onset of the disease is associated with increased risk of breast cancer. We report on three independent prospective nested case-control studies from the European Prospective Investigation into Cancer and Nutrition (EPIC-Italy; n = 162 matched case-control pairs), the Norwegian Women and Cancer study (NOWAC; n = 168 matched pairs), and the Breakthrough Generations Study (BGS; n = 548 matched pairs). We used the Illumina 450k array to measure methylation in the EPIC and NOWAC cohorts. Whole-genome bisulphite sequencing (WGBS) was performed on the BGS cohort using pooled DNA samples, combined to reach 50× coverage across ~16 million CpG sites in the genome including 450k array CpG sites. Mean β values over all probes were calculated as a measurement for epigenome-wide methylation
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