Nutritional Status of Households of Rural Field Practice Area of a Tertiary Care Hospital in India

Introduction: In the world as a whole there appears to be a shift from under-nourishment towards over-nourishment making more and more children, adolescents, adults and even elderly to be overweight and obese. Objectives: Study aimed to find out the age and sex wise commonness of over-weight & obesity amongst the families of an overtly different socio-economic environment and its trend in the members of one type of families. Materials & Methods: The undergraduate medical students are supposed to maintain record of individual health (including height & weight) of their own family as well as that of the allotted family. The data collected (record maintained ) by students was utilized to calculate Body Mass Index (BMI). Results: Out of total 291 subjects (males 168; females 123) in students own family 28.9% (28.0%; 30.1%) were overweight and 5.9% (6.0%; 5.7%) were obese. The similar figures for 262 subjects (males 143 & females 119) in the allotted families were 20.2% (18.5%; 20.2%) and 6.5% (4.2%; 8.4%) respectively. The respective percentages of under nourished individuals were 18.6 (17.9; 19.5) and 35.5 (37.8; 32.8). Thus over-nutrition was more common amongst the members of students own families (34.8% vs. 26.7%) and under-nutrition was more common amongst the members of allotted families (35.5% vs. 18.6%) For the years 2000-2003, BMI amongst individuals of students own families the under-nutrition in the age group of 15-24 years amongst males increased from 15.9% to 32.9% and over-nutrition from 13.6% to 20.5%. There was no case of overweight and obesity up to the age of 34 years in the previous analysis which was 2.6% in the present analysis Previous results demonstrated overweight to be more common in males (32.4% Vs. 24.4% in females) and obesity being more common females ( 6.3% Vs. 2.6% in females). Conclusion: Males are increasingly becoming prey of malnutrition (adolescents for under-nutrition and adults & elderly for over-nutrition. More studies covering larger samples are required to be conducted on a more frequent basis

Efficacy of antioxidant supplementation on conventional and advanced sperm function tests in patients with idiopathic male infertility.

Antioxidants are used in the empirical treatment of infertile men. The aim of this study was to evaluate the effects of antioxidant therapy on conventional semen parameters and advanced sperm function tests in men seeking fertility treatment. A total of 148 infertile men of unknown etiology were divided into idiopathic (n = 119) and unexplained male infertility (UMI; n = 29). All participants were treated with the antioxidant supplement 'FH PRO for Men' for a period of three months. Compared with pretreatment results, there was a significant improvement in conventional semen parameters including sperm concentration, total and progressive motility and normal morphology, and seminal oxidation reduction potential (ORP), and sperm DNA fragmentation (SDF) in idiopathic infertile men. The changes were more prominent in idiopathic infertile men positive for ORP and SDF. UMI patients showed an improvement in progressive motility, ORP, and SDF after antioxidant treatment. Statistical analysis revealed that the efficacy of FH PRO for Men was significant in idiopathic male infertility compared with UMI. Treatment of idiopathic male infertility patients with the FH PRO for Men antioxidant regimen for three months resulted in a significant improvement in conventional semen parameters and sperm function. Therefore, FH PRO for Men offers promise for the medical treatment of idiopathic male infertility

Highly Cited Articles in the Field of Male Infertility and Antioxidants: A Scientometric Analysis

Purpose The objective of this scientometric analysis was to recognize the top 100 cited articles on ‘Male infertility and Antioxidants’ and analyze its publication characteristics. Materials and Methods The Scopus database was used to retrieve related articles and the top 100 identified based on citation rate. Results The articles were published in 56 journals between 1995 and 2019 with a median (interquartile range) citation score of 17 (5–62). Among the top 100 articles, 69 were clinical studies, which included controlled and blinded (33.33%), prospective (27.54%), randomized-controlled trials (26.09%), uncontrolled (11.59%), and retrospective (1.45%) studies. In addition to conventional semen parameters, advanced sperm function tests such as oxidative stress (51%) and sperm DNA damage (23%) were reported. Pregnancy rate (33%) was found to be the most reported reproductive outcome. Antioxidant therapy was mostly investigated in male cohorts with sperm abnormalities such as asthenozoospermia (28%) and clinical conditions such as idiopathic male infertility (20%), varicocele/varicocelectomy (17%) and general male infertility (16%). Conclusions The most influential publications on antioxidants and male infertility were identified for the first time in the literature. This will serve as a reliable source of information for researchers and clinicians alike

Duality between N=5 and N=6 Chern-Simons matter theory

We provide evidences for the duality between ${\cal N}=6$ $U(M)_{4} \times U(N)_{-4}$ Chern-Simons matter theory and ${\cal N}=5$ $O(\hat{M})_{2} \times USp(2\hat{N})_{-1}$ theory for a suitable $\hat{M},\hat{N}$ by working out the superconformal index, which shows perfect matching. For ${\cal N}=5$ theories, we show that supersymmetry is enhanced to ${\cal N}=6$ by explicitly constructing monopole operators filling in $SO(6)_R$ $R$-currents. Finally we work out the large $N$ index of $O(2N)_{2k} \times USp(2N)_{-k}$ and show that it exactly matches with the gravity index on $AdS_4 \times S^7/D_k$, which further provides additional evidence for the duality between the ${\cal N}=5$ and ${\cal N}=6$ theory for $k=1$Comment: 15 pages; references adde

Male fertility and the COVID-19 pandemic: systematic review of the literature

Purpose Since its discovery in December 2019, the novel coronavirus SARS-CoV-2 has spread globally, causing the current COVID-19 (coronavirus disease-19) pandemic. As there is an increase of infections in the male population, concerns have emerged about the potential impact of COVID-19 on male reproductive organs and male fertility. Therefore, this study systematically investigates the current evidence of SARS-CoV-2 impact on male reproduction and pregnancy outcomes, discussing them in light of the evidence published on other coronaviruses. Materials and Methods Literature search was carried out according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A total of 24 original articles were included for the analysis, investigating the effects of the infection on semen parameters, male reproductive hormones, and pregnancy outcomes. Further, a Strengths-Weaknesses-Opportunities-Threats (SWOT) analysis was conducted based on the available evidence linking the virus with male reproduction and conception. Results Although there is limited data, viral mRNA has been identified in semen of infected men, with some evidence of altered seminal parameters. Low testosterone and dihydrotestosterone with raised luteinizing hormone has been reported as well as preterm delivery in pregnant women; however, data regarding vertical transmission remains contradictory and inconclusive. Conclusions The recent literature provides evidence that male gonads may be potentially vulnerable to SARS-CoV-2 infection, recommending caution to pregnant women and couples planning natural pregnancy or assisted reproduction

Applications of Direct Injection Soft Chemical Ionisation-Mass Spectrometry for the Detection of Pre-blast Smokeless Powder Organic Additives

Analysis of smokeless powders is of interest from forensics and security perspectives. This article reports the detection of smokeless powder organic additives (in their pre-detonation condition), namely the stabiliser diphenylamine and its derivatives 2-nitrodiphenylamine and 4-nitrodiphenylamine, and the additives (used both as stabilisers and plasticisers) methyl centralite and ethyl centralite, by means of swab sampling followed by thermal desorption and direct injection soft chemical ionisation-mass spectrometry. Investigations on the product ions resulting from the reactions of the reagent ions H3O+ and O2+ with additives as a function of reduced electric field are reported. The method was comprehensively evaluated in terms of linearity, sensitivity and precision. For H3O+, the limits of detection (LoD) are in the range of 41-88 pg of additive, for which the accuracy varied between 1.5 and 3.2%, precision varied between 3.7 and 7.3% and linearity showed R20.9991. For O2+, LoD are in the range of 72 to 1.4 ng, with an accuracy of between 2.8 and 4.9% and a precision between 4.5 and 8.6% and R20.9914. The validated methodology was applied to the analysis of commercial pre-blast gun powders from different manufacturers.(VLID)4826148Accepted versio