2,148 research outputs found
Foreword
This report provides a study and a simulation of a feasible system configuration for the implementation of a Stirling engine for electrification of rural areas in Bolivia. The aim of the review is to determine if a hybrid system combining a biomass-fired Stirling engine and photovoltaic technology may respond to a basic electricity need. An introductory literature study about the Stirling engine technology and the energy resources and characteristics of Bolivia leads to a further proposal of the selected system for rural electrification. The chosen Stirling engine for this study is a 3 kW electric output engine combined with a PV array of 0.9 kW and a battery bank with a capacity of 1200 Ah. The power demand that must be satisfied is based on a rural village in the department of Beni with an amount of 24 households. The simulation is performed in the software Homer Energy where an energy balance between the generated power and the demand can be analysed in order to optimise the power generation strategy. Two scenarios are simulated with monthly demands of 45 and 60 kWh per household. Results from the study indicate that the decision on the size of the Stirling engine must be attached to the demand that is going to satisfy in order to avoid insufficient or excessive power production. In addition, although the PV technology allows an increase on the power demand that the system can handle and makes it more flexible, its contribution is not of the same order of the Stirling engine. The described system configuration is able to attend a demand up to 55 kWh/day and a peak power of 3.8 kW. In conclusion, Stirling engines have the potential to become a good solution for rural electrification, especially when making use of CHP strategies to increase the overall efficiency of the energy generation and fulfil both the electric and thermal demands of rural populations.
Saccharomyces Cerevisiae sec59 Cells Are Deficient in Dolichol Kinase Activity
The temperature-sensitive Saccharomyces cerevisiae mutant sec59 accumulates inactive and incompletely glycosylated protein precursors in its endoplasmic reticulum at the restrictive temperature. O-mannosylation and glycosyl phosphatidylinositol membrane anchoring of protein are also abolished, consistent with a deficiency in dolichyl phosphate mannose. Membranes prepared from sec59 cells that had been shifted to the restrictive temperature, however, made normal amounts of dolichyl phosphate mannose when exogenous dolichyl phosphate was supplied, but dolichyl phosphate mannose synthesis was severely depressed in the absence of exogenous dolichyl phosphate. Quantitative measurements of dolichyl phosphate in sec59 cells showed that the levels were decreased to 48% of wild type at the permissive temperature and to less than 10% at the restrictive temperature. Assays of enzymes from the dolichyl phosphate synthetic pathway, cis-prenyltransferase and dolichyl pyrophosphate phosphatase, gave wild-type levels. However, dolichol kinase activity was greatly decreased. When sec59 cells were transformed with a plasmid that overexpresses the wild-type gene, dolichol kinase activity increased 10-fold over wild-type levels. These results strongly suggest that the sec59 gene encodes dolichol kinase
The Involvement of Purinergic System in Pain: Adenosine Receptors and Inosine as Pharmacological Tools in Future Treatments
Correspondence to Elizabeth ( Bessie ) McCaw Boggs Taylor, August 31, 1888 - December 10, 1901
Correspondence to Elizabeth ( Bessie ) McCaw Boggs Taylor, August 31, 1888 - December 10, 1901.
Box 2, folder 5.https://digitalcommons.wofford.edu/littlejohnboggs/1015/thumbnail.jp
Perfil sociodemográfico e de experiências anômalas em indivíduos com vivências psicóticas e dissociativas em grupos religiosos
CONTEXTO: Vivências psicóticas e dissociativas não patológicas são comuns na população geral, especialmente em grupos religiosos. Há poucos estudos sobre o perfil da população não clínica com essas vivências, bem como há dúvidas sobre critérios para o diagnóstico diferencial dessas experiências. OBJETIVOS: Identificar o perfil sociodemográfico e de experiências anômalas (EA) entre pessoas que buscaram ajuda em centros espíritas. MÉTODOS: Foram entrevistadas 115 pessoas que procuraram auxílio em seis centros espíritas de Juiz de Fora/MG por causa de vivências psicóticas e/ou dissociativas. Entrevista semiestruturada investigou dados sociodemográficos, experiências anômalas apresentadas e a presença de critérios propostos para identificar experiências espirituais não patológicas. RESULTADOS: Predomínio de mulheres (70%), de meia-idade, com alta escolaridade, ativas ocupacionalmente e cujas EA começaram na infância (65%) ou adolescência (23%). As EA mais frequentes foram alucinações visuais (63%), auditivas (54%), "percepção espiritual" (53%), "sonhos paranormais" (38%) e experiências fora do corpo (31%). Para a maioria da amostra, essas EA não traziam prejuízos sócio-ocupacionais, eram curtas, episódicas e benéficas; entretanto referiram sofrimento emocional e falta de controle sobre elas. CONCLUSÃO: A alta frequência e diversidade de EA encontradas, bem como suas implicações teóricas, clínicas e de saúde pública, indicam a urgência de maior atenção a esse tópico
Sociodemographic and anomalous experiences profile in subjects with psychotic and dissociative experiences in religious groups
CONTEXTO: Vivências psicóticas e dissociativas não patológicas são comuns na população geral, especialmente em grupos religiosos. Há poucos estudos sobre o perfil da população não clínica com essas vivências, bem como há dúvidas sobre critérios para o diagnóstico diferencial dessas experiências. OBJETIVOS: Identificar o perfil sociodemográfico e de experiências anômalas (EA) entre pessoas que buscaram ajuda em centros espíritas. MÉTODOS: Foram entrevistadas 115 pessoas que procuraram auxílio em seis centros espíritas de Juiz de Fora/MG por causa de vivências psicóticas e/ou dissociativas. Entrevista semiestruturada investigou dados sociodemográficos, experiências anômalas apresentadas e a presença de critérios propostos para identificar experiências espirituais não patológicas. RESULTADOS: Predomínio de mulheres (70%), de meia-idade, com alta escolaridade, ativas ocupacionalmente e cujas EA começaram na infância (65%) ou adolescência (23%). As EA mais frequentes foram alucinações visuais (63%), auditivas (54%), "percepção espiritual" (53%), "sonhos paranormais" (38%) e experiências fora do corpo (31%). Para a maioria da amostra, essas EA não traziam prejuízos sócio-ocupacionais, eram curtas, episódicas e benéficas; entretanto referiram sofrimento emocional e falta de controle sobre elas. CONCLUSÃO: A alta frequência e diversidade de EA encontradas, bem como suas implicações teóricas, clínicas e de saúde pública, indicam a urgência de maior atenção a esse tópico.BACKGROUND: Non-pathological psychotic and dissociative experiences are frequent in the general population, particularly in religious groups. There are few studies on the profile of non-clinical populations with these experiences, and on criteria for differential diagnosis. OBJECTIVES: To identify the sociodemographic profile and anomalous experiences (AE) among people who sought help in spiritualist groups. METHODS: We interviewed 115 people who sought assistance in six spiritualist groups in the city of Juiz de Fora/MG due to psychotic and/or dissociative experiences. Semi-structured interviews investigated sociodemographic data, AEs reported and presence of criteria that have been proposed to identify non-pathological spiritual experiences. RESULTS: sample was mostly composed by women (70%), middle age, high educational level, whose AEs started in childhood (65%) and adolescence (23%). The most frequent AEs were visual (63%) and auditory (54%) hallucinations, "spiritual perception" (53%), "paranormal dreams" (38%) and out-of-body experiences (31%). Most of the sample reported that these AEs were not related to socio-occupational impairments, were short, episodic, and beneficial; however, reported emotional distress and lack of control over the experiences. DISCUSSION: The high frequency and diversity of AEs reported, as well as their theoretical, clinical, and public health implications point to the urgency need of more attention to this topic
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