94 research outputs found
Preparation of chiral ruthenium(IV) complexes and applications in regio- and enantioselective allylation of phenols.
International audienceFacile preparations of chiral [Ru(Cp*)]- and [Ru(Cp')]-based allyl complexes featuring N,O chelate derived from (+)-nopinone are described. Single crystal X-ray structural analysis of one complex revealed the preferential configuration of the ruthenium centre and the orientation of the unsymmetrical allylic substituent. Applications of these complexes in catalysis for nucleophilic allylic substitution allowed regio- and enantioselective formation of branched allyl ethers from phenols
Plant responses to photoperiod
Photoperiod controls many developmental responses in animals, plants and even fungi. The response to photoperiod has evolved because daylength is a reliable indicator
of the time of year, enabling developmental events to be scheduled to coincide with particular environmental conditions. Much progress has been made towards
understanding the molecular mechanisms involved in the response to photoperiod in plants. These mechanisms include the detection of the light signal in the leaves,
the entrainment of circadian rhythms, and the production of a mobile signal which is transmitted throughout the plant. Flowering, tuberization and bud set are just a few of the many different responses in plants that are under photoperiodic control. Comparison of what is known of the molecular mechanisms controlling these responses shows that, whilst common components exist, significant differences in the regulatory mechanisms have evolved between these responses
Closing in on a perturbative fourth generation
A perturbative new family of fermions is now severely constrained, though not
excluded yet. We reconsider the current bounds (i.e., direct and from Higgs
searches, R_b, oblique parameters) on the fourth generation parameter space
assuming the case of a small CKM mixing with the third generation. We identify
viable scenarios featuring either a light or a heavy Higgs boson. A set of
representative benchmark points targeted for LHC searches is proposed with a
normal (inverted) quark mass hierarchy where t' -> b'W (b' -> tW) decays are
sizable. In the case where the fourth generation couplings to the lighter quark
families are small, we suggest that search strategies at the LHC should include
both pair (strong) and single (weak) production with bb+nW (n=2,...,6) final
state signatures.Comment: 23 pages, 6 figures, v2: some issues clarified and references added.
To appear in JHE
Regulation of reproductive development by non-coding RNA in Arabidopsis: to flower or not to flower
Méthodes alternatives in silico dans le cadre de REACH (les modèles (Q)SARs, les catégories chimiques, l'analyse de tendance et les références croisées dans le cadre du règlement REACH. Quels sont les outils disponibles et quelle méthodologie mettre en place ? Méthode illustrée par l'exemple d'un tensioactif)
PARIS-BIUP (751062107) / SudocSudocFranceF
Vicinal α,β-Functionalizations of Amines: Cyclization Versus Dehydrogenative Hydrolysis
International audienceDirect vicinal α,β-difunctionalization of tertiary cyclic amines is achieved in the presence of ruthenium or iridium transition-metal complexes featuring phosphine-sulfonate chelates. By varying the reaction conditions, α-alkylated lactams were obtained by a formal dehydrogenative hydrolysis in which one molecule of hydrogen is generated from water
Transition metal catalyzed nucleophilic allylic substitution: activation of allylic alcohols via π-allylic species.
International audienceModern organic synthesis now requires efficient atom economical synthetic methods operating under greener pathways to achieve C-C and C-heteroatom bond formation. Direct activation of allylic alcohols in the presence of transition metal catalysts leading to electrophilic π-allyl metal intermediates represents such a promising target in the field of nucleophilic allylation reactions. During the last decade, this topic of recognized importance has become an emerging area, and selected transition metals, sometimes associated with alcohol activators, have brought elegant solutions for performing allylic substitution directly from alcohols in a regio, stereo and enantioselective manner
- …