3,373 research outputs found
Inelastic effects in molecular junctions in the Coulomb and Kondo regimes: Nonequilibrium equation-of-motion approach
Inelastic effects in the Coulomb blockade and Kondo regimes of electron
transport through molecular junctions are considered within a simple
nonequilibrium equation-of-motion (EOM) approach. The scheme is
self-consistent, and can qualitatively reproduce the main experimental
observations of vibrational features in Coulomb blockade [H.Park et al., Nature
407, 57 (2000)] and Kondo [L.H.Yu et al., Phys. Rev. Lett. 93, 266802 (2004)]
regimes. Considerations similar to the equilibrium EOM approach by Meir et al.
[Phys. Rev. Lett. 66, 3048 (1991); ibid. 70, 2601 (1993)] are used on the
Keldysh contour to account for the nonequilibrium nature of the junction, and
dressing by appropriate Franck-Condon (FC) factors is used to account for
vibrational features. Results of the equilibrium EOM scheme by Meir et al. are
reproduced in the appropriate limit.Comment: 12 pages, 5 figure
Parks, people and pixels: evaluating landscape effects of an East African national park on its surroundings
Landscapes surrounding protected areas, while still containing considerable biodiversity, have rapidly growing human populations and associated agricultural development in most of the developing world that tend to isolate them, potentially reducing their conservation value. Using field studies and multi-temporal Landsat imagery, we examine a forest park, Kibale National Park in western Uganda, its changes over time, and related land cover change in the surrounding landscape. We find Kibale has successfully defended its borders and prevents within-park deforestation and other land incursions, and has maintained tree cover throughout the time period of the study. Outside the park there was a significant increase in tea plantations and continued forest fragmentation and wetland loss. The question of whether the park is a conservation success because of the network of forest fragments and wetlands or in spite of them remains unanswered
Trust, regulatory processes and NICE decision-making: Appraising cost-effectiveness models through appraising people and systems.
This article presents an ethnographic study of regulatory decision-making regarding the cost-effectiveness of expensive medicines at the National Institute for Health and Care Excellence (NICE) in England. We explored trust as one important mechanism by which problems of complexity and uncertainty were resolved. Existing studies note the salience of trust for regulatory decisions, by which the appraisal of people becomes a proxy for appraising technologies themselves. Although such (dis)trust in manufacturers was one important influence, we describe a more intricate web of (dis)trust relations also involving various expert advisors, fellow committee members and committee Chairs. Within these complex chains of relations, we found examples of both more blind-acquiescent and more critical-investigative forms of trust as well as, at times, pronounced distrust. Difficulties in overcoming uncertainty through other means obliged trust in some contexts, although not in others. (Dis)trust was constructed through inferences involving abstract systems alongside actorsâ oral and written presentations-of-self. Systemic features and âforced optionsâ to trust indicate potential insidious processes of regulatory capture
Molecular transport junctions: Current from electronic excitations in the leads
Using a model comprising a 2-level bridge connecting free electron reservoirs
we show that coupling of a molecular bridge to electron-hole excitations in the
leads can markedly effect the source-drain current through a molecular
junction.In some cases, e.g. molecules that exhibit strong charge transfer
transitions, the contribution from electron-hole excitations can exceed the
Landauer elastic current and dominate the observed conduction.Comment: 4 pages, 2 figures, submitted to PR
Lagrangian and Hamiltonian two-scale reduction
Studying high-dimensional Hamiltonian systems with microstructure, it is an
important and challenging problem to identify reduced macroscopic models that
describe some effective dynamics on large spatial and temporal scales. This
paper concerns the question how reasonable macroscopic Lagrangian and
Hamiltonian structures can by derived from the microscopic system.
In the first part we develop a general approach to this problem by
considering non-canonical Hamiltonian structures on the tangent bundle. This
approach can be applied to all Hamiltonian lattices (or Hamiltonian PDEs) and
involves three building blocks: (i) the embedding of the microscopic system,
(ii) an invertible two-scale transformation that encodes the underlying scaling
of space and time, (iii) an elementary model reduction that is based on a
Principle of Consistent Expansions.
In the second part we exemplify the reduction approach and derive various
reduced PDE models for the atomic chain. The reduced equations are either
related to long wave-length motion or describe the macroscopic modulation of an
oscillatory microstructure.Comment: 40 page
Malaria vector control at crossroads: public health entomology and the drive to elimination
Vector control has been at the core of successful malaria control. However, a dearth of field-oriented vector biologists threatens to undermine global reductions in malaria burden. Skilled cadres are needed to manage insecticide resistance, to maintain coverage with current interventions, to develop new paradigms for tackling âresidual' transmission, and to target interventions as transmission becomes increasingly heterogeneous. Recognising this human resource crisis, in September 2013, WHO Global Malaria Programme issued guidance for capacity building in entomology and vector control, including recommendations for countries and implementing partners. Ministries were urged to develop long-range strategic plans for building human resources for public health entomology and vector control (including skills in epidemiology, geographic information systems, operational research and programme management) and to set in place the requisite professional posts and career opportunities. Capacity building and national ownership in all partner projects and a clear exit strategy to sustain human and technical resources after project completion were emphasised. Implementing partners were urged to support global and regional efforts to enhance public health entomology capacity. While the challenges inherent in such capacity building are great, so too are the opportunities to establish the next generation of public health entomologists that will enable programmes to continue on the path to malaria eliminatio
Convergent Chaos
Chaos is widely understood as being a consequence of sensitive dependence upon initial conditions. This is the result of an instability in phase space, which separates trajectories exponentially. Here, we demonstrate that this criterion should be refined. Despite their overall intrinsic instability, trajectories may be very strongly convergent in phase space over extremely long periods, as revealed by our investigation of a simple chaotic system (a realistic model for small bodies in a turbulent flow). We establish that this strong convergence is a multi-facetted phenomenon, in which the clustering is intense, widespread and balanced by lacunarity of other regions. Power laws, indicative of scale-free features, characterize the distribution of particles in the system. We use large-deviation and extreme-value statistics to explain the effect. Our results show that the interpretation of the 'butterfly effect' needs to be carefully qualified. We argue that the combination of mixing and clustering processes makes our specific model relevant to understanding the evolution of simple organisms. Lastly, this notion of convergent chaos, which implies the existence of conditions for which uncertainties are unexpectedly small, may also be relevant to the valuation of insurance and futures contracts
Phase transitions and configuration space topology
Equilibrium phase transitions may be defined as nonanalytic points of
thermodynamic functions, e.g., of the canonical free energy. Given a certain
physical system, it is of interest to understand which properties of the system
account for the presence of a phase transition, and an understanding of these
properties may lead to a deeper understanding of the physical phenomenon. One
possible approach of this issue, reviewed and discussed in the present paper,
is the study of topology changes in configuration space which, remarkably, are
found to be related to equilibrium phase transitions in classical statistical
mechanical systems. For the study of configuration space topology, one
considers the subsets M_v, consisting of all points from configuration space
with a potential energy per particle equal to or less than a given v. For
finite systems, topology changes of M_v are intimately related to nonanalytic
points of the microcanonical entropy (which, as a surprise to many, do exist).
In the thermodynamic limit, a more complex relation between nonanalytic points
of thermodynamic functions (i.e., phase transitions) and topology changes is
observed. For some class of short-range systems, a topology change of the M_v
at v=v_t was proved to be necessary for a phase transition to take place at a
potential energy v_t. In contrast, phase transitions in systems with long-range
interactions or in systems with non-confining potentials need not be
accompanied by such a topology change. Instead, for such systems the
nonanalytic point in a thermodynamic function is found to have some
maximization procedure at its origin. These results may foster insight into the
mechanisms which lead to the occurrence of a phase transition, and thus may
help to explore the origin of this physical phenomenon.Comment: 22 pages, 6 figure
Book Reviews
Wesleyan Perspectives on the New Creation
M. Douglas Meeks, ed.
Nashville: Kingswood,
2004, 200 pp., paper, 2004, 25.00
Reviewed by Elaine A. Heath
The Evangelical Moment: The Promise of an American Religion
By Kenneth J. Collins
Grand Rapids: Baker Academic Press
2005, 288 pp., paper, 22.99
Reviewed by Nathan Crawford
Theology as History and Hermeneutics: A Post-Critical Evangelical Conversation with Contemporary Theology
Laurence W. Wood
Lexington: Emeth Publisher
2004, 261 pp.
Reviewed by Nathan Crawford
Resistance and Theological Ethics
Ronald H. Stone and Robert L. Stivers, eds.
Lanham, Maryland: Roman & Littlefield Publishers
2004, ri, 334 pp. paper, 28.95
Reviewed by Joerg Rieger
The Ripple Church: Multiply Your Ministry by Parenting New Churches
Phil Stevenson
Indianapolis, IN: Wesleyan Publishing House
2004. pp. 186, 35.00
Reviewed by John N. Oswalt
God is Not Religious, Nice, One of Us, an American, a Capitalist
D. Brent Laytham, ed.
Grand Rapids, Michigan: Press.
2004, 152 pp., paper, 19.95
Reviewed by Charles M. Woo
Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
SummaryMaster transcription factors Oct4, Sox2, and Nanog bind enhancer elements and recruit Mediator to activate much of the gene expression program of pluripotent embryonic stem cells (ESCs). We report here that the ESC master transcription factors form unusual enhancer domains at most genes that control the pluripotent state. These domains, which we call super-enhancers, consist of clusters of enhancers that are densely occupied by the master regulators and Mediator. Super-enhancers differ from typical enhancers in size, transcription factor density and content, ability to activate transcription, and sensitivity to perturbation. Reduced levels of Oct4 or Mediator cause preferential loss of expression of super-enhancer-associated genes relative to other genes, suggesting how changes in gene expression programs might be accomplished during development. In other more differentiated cells, super-enhancers containing cell-type-specific master transcription factors are also found at genes that define cell identity. Super-enhancers thus play key roles in the control of mammalian cell identity
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