Studies on in vitro antioxidant activities of nine diff erent fruit tree leaves collected from Mediterranean region of Turkey

To investigate antioxidant of the methanolic and water extracts obtained from nine different fruit tree leaves(avocado, walnut, mulberry, fig, carob, lemon, pomegranate, grape, and loquat) collected from Mediterraneanregion of Turkey. The antioxidant activities were evaluated with different in vitro antioxidant assays includingphosphomolybdate assay, free radical scavenging assays (•OH, NO, and O2−), β-carotene/linoleic acid testsystem, and ferric reducing power. The contents of saponin and tannin in extracts were also determined. Thepresent study suggests that the extracts were good radical scavengers. These results suggest that the extractsexamined should be beneficial as a source of natural agents for the food industry and pharmacological applications

A New Source of Natural Antioxidants From Turkey: Linaria GenistifoliaSubsp. Genistifolia

The antioxidant properties of different solvent extracts (acetone, methanol and water) from Linaria genistifolia subsp. genistifolia were investigated. Antioxidant properties were evaluated by different methods including free radical scavenging (DPPH and ABTS), reducing power (CUPRAC and FRAP), phosphomolybdenum, β-carotene/linoleic acid and metal chelating assays. Also, total phenolic and flavonoid content were determined for each extracts. Generally, the acetone and methanol extracts exhibited strong antioxidant abilities with higher level of phenolics (40.17 mgGAEs/g for acetone and 28.18 mgGAEs/g for methanol). All extracts had remarkable inhibition abilities of linoleic acid oxidation (84.88% for acetone, 77.22% for methanol and 63.04 for water). The results indicate that Linaria genistifolia subsp. genistifolia could be considered as a source of natural antioxidant for preparing new food ingredients and pharmaceutical formulations

INVESTIGATION OF ANTIOXIDANT POTENTIALS OF SOLVENT EXTRACTS FROM DIFFERENT ANATOMICAL PARTS OF ASPHODELINE ANATOLICA E. TUZLACİ: AN ENDEMIC PLANT TO TURKEY

Background: The genus Asphodeline (Liliaceae) is represented in Turkey by 20 taxa, which are traditionally used for medicinal purposes in Anatolia. Materials and Methods: In this study, we tested the phytochemical content and antioxidant effect of different solvent extracts obtained from different anatomical parts of Asphodeline anatolica. The different extracts of each plant parts were tested for antioxidant activity using different chemical assays. The total antioxidant components were also calculated. Results: Generally, acetone extracts produced the seed and root exhibited significantly higher antioxidant activity with high antioxidant components. Total phenolic content of extracts were significantly correlated with antioxidant potentials (except for, metal chelating activity). Conclusion: On the basis of the results obtained, A. anatolica extracts should be regarded as a valuable source of natural antioxidants for food and therapeutic applications

Fatty acid composition of fl owers of Crepis foetida subsp. rhoeadifolia from Turkey

This study aims to describe the fatty acid composition of flowers of Crepis foetida subsp. rhoeadifolia. In order todefine qualitative and quantitative profile, fatty acids were derived to their methyl esters, and then these wereanalyzed by gas chromatography - flame ionization detector. 20 fatty acids were determined in the oil. Palmitic(C 16:0), myristic (C 14:0), and linoleic acids (18:2 ω6) were found to be major fatty acids. Total saturatedfatty acids, monounsaturated fatty acids, and polyunsaturated fatty acids (PUFA) were 62.67%, 17.54%, and19.79%, respectively. Also, total essential fatty acids (EFA) were determined ad 14.48%. Therefore, the oil canbe considered as a new source of PUFA, especially EFA

Capacidad antioxidante y perfil de ácidos grasos de Centaurea kotschyi (Boiss. & Heldr.) Hayek var. persica (Boiss.) Wagenitz de Turquía

The antioxidant capacity of the methanolic extract and the fatty acid composition of C. kotschyi var. persica were investigated. Six different chemical methods were used to determine the antioxidant capacity. The fatty acid composition was analyzed using gas chromatography. The IC50 value of the extract was determined as 37.09 μg/ml (in the DPPH assay). In the β-carotene/linoleic acid system, the extract exhibited 65.22% inhibition against linoleic acid oxidation. The amount of total phenolic content and total antioxidant capacity were detected as 36.52 mg gallic acid equivalent (GAE)/g and 74.93 mg ascorbic acid equivalent (AE)/g, respectively. The major fatty acid in the composition of C. kotschyi var. persica was found to be C 18:3 ω3 (α-linolenic acid) by GC analysis. The results presented here indicate that C. kotschyi var. persica possess strong antioxidant properties. Therefore, the species can be used as a natural additive in food, cosmetic and pharmaceutical industries.La capacidad antioxidante de extractos metanólicos y composición de ácidos grasos de C. kotschyi var. pérsica fueron investigados. Seis métodos químicos diferentes fueron realizados para la determinación de la capacidad antioxidante. La composición de ácidos grasos fue analizada por cromatografía de gases. Los valores de IC50 de los extractos fueron 37.09 μg/ml (en el ensayo con DPPH). En el sistema β-carotene/ácido linoleico, el extracto mostró un 65.22% de inhibición frente a la oxidación del ácido linoleico. La cantidad total de contenido fenólico y capacidad antioxidante total fueron 36.52 mg equivalentes de ácido gallico (GAE)/g y 74.93 mg equivalentes de ácido ascórbico (AE)/g, respectivamente. El principal ácidos graso encontrado, por análisis de CG, en C. kotschyi var. pérsica fue el C 18:3 ω3 (ácido α-linolenico). Los resultados presentados aquí indican que C. kotschyi var. pérsica posee unas fuertes propiedades antioxidantes. Además, las especies pueden ser usadas como aditivos naturales en los alimentos, en cosmética y en industria farmacéutica

Effects of different fat sources on fatty acid composition and CLA content of some tissues of laying hens

Effects of different fat sources on fatty acid composition and the CLA contents of some tissues of laying hens were investigated by gas chromatographic method. In this study, the control (group I), tallow (group II), the internal fat (group III) and the tail fat (group IV), obtained by diets of laying hens with abdominal fat, skin and breast meat + leg were investigated. A total of 160 units, 22-week-old laying hens Hy-line strain used. 40 chickens were used in each group. According to the plan the randomized study, for 10 replications each treatment group, and each iteration is used for the 4 chicken. 18-Hour light-dark day 6 hours' lighting program applied the trial lasted for 12 weeks, feed and water is provided. Total 30 different fatty acids were determined in fatty acid compositions of some tissues. These fatty acids were varied between C 8 - C 22. Different fat sources added that dietary has led to important differences in the of fatty acids composition in abdominal adipose tissue (P<0.05). Diets containing saturated fatty acids, rich oil resources abdominal adipose tissue increased the saturated fatty acid content, diets containing fat sources rich in unsaturated fatty acids increased the unsaturated fatty acid content of abdominal adipose tissue. Animal fat diets of laying hens., especially with addition of the tail fat, skin, leg and breast meat the amount of the total CLA except of amount for abdominal fat statistically significant increased. After 90 days analysing amount of CLA all of the tissues was found to be the highest

Novel 1,3-thiazolidin-4-one derivatives as promising anti-Candida agents endowed with anti-oxidant and chelating properties

Pursuing our recent outcomes regarding the antifungal activity of N-substituted 1,3-thiazolidin-4-ones, we synthesized thirty-six new derivatives introducing aliphatic, cycloaliphatic and heteroaromatic moieties at N1-hydrazine connected with C2 position of the thiazolidinone nucleus and functionalizing the lactam nitrogen with differently substituted (NO2, NH2, Cl and F) benzyl groups. These compounds were tested to evaluate their minimum inhibitory concentration (MIC) against several clinical Candida spp. with respect to topical and systemic reference drugs (clotrimazole, fluconazole, ketoconazole, mi- conazole, tioconazole, amphotericin B). Moreover, anti-oxidant properties were also evaluated by using different protocols including free radical scavenging (DPPH and ABTS), reducing power (CUPRAC and FRAP), metal chelating and phosphomolybdenum assays. Moreover, for the most active derivatives we assessed the toxicity (CC50) against Hep2 human cells in order to characterize them as multi-target agents for fungal infections

Total Phenolics, Flavonoids, Condensed Tannins Content of Eight Centaurea Species and Their Broad Inhibitory Activities against Cholinesterase, Tyrosinase, α-Amylase and α-Glucosidase

Selcuk UniversitySelcuk Universit

Antioxidant capacity and fatty acid profile of <i>Centaurea kotschyi</i> (Boiss. & Heldr.) Hayek var. <i>persica</i> (Boiss.) Wagenitz from Turkey

The antioxidant capacity of the methanolic extract and the fatty acid composition of <i>C. kotschyi</i> var. <i>persica</i> were investigated. Six different chemical methods were used to determine the antioxidant capacity. The fatty acid composition was analyzed using gas chromatography. The IC50 value of the extract was determined as 37.09 μg/ml (in the DPPH assay). In the β-carotene/linoleic acid system, the extract exhibited 65.22% inhibition against linoleic acid oxidation. The amount of total phenolic content and total antioxidant capacity were detected as 36.52 mg gallic acid equivalent (GAE)/g and 74.93 mg ascorbic acid equivalent (AE)/g, respectively. The major fatty acid in the composition of <i>C. kotschyi</i> var. <i>persica</i> was found to be C 18:3 ω3 (α-linolenic acid) by GC analysis. The results presented here indicate that <i>C. kotschyi</i> var. <i>persica</i> possess strong antioxidant properties. Therefore, the species can be used as a natural additive in food, cosmetic and pharmaceutical industries.<br><br>La capacidad antioxidante de extractos metanólicos y composición de ácidos grasos de <i>C. kotschyi</i> var. <i>pérsica</i> fueron investigados. Seis métodos químicos diferentes fueron realizados para la determinación de la capacidad antioxidante. La composición de ácidos grasos fue analizada por cromatografía de gases. Los valores de IC50 de los extractos fueron 37.09 μg/ml (en el ensayo con DPPH). En el sistema β-carotene/ácido linoleico, el extracto mostró un 65.22% de inhibición frente a la oxidación del ácido linoleico. La cantidad total de contenido fenólico y capacidad antioxidante total fueron 36.52 mg equivalentes de ácido gallico (GAE)/g y 74.93 mg equivalentes de ácido ascórbico (AE)/g, respectivamente. El principal ácidos graso encontrado, por análisis de CG, en <i>C. kotschyi</i> var. <i>pérsica</i> fue el C 18:3 ω3 (ácido α-linolenico). Los resultados presentados aquí indican que <i>C. kotschyi</i> var. <i>pérsica</i> posee unas fuertes propiedades antioxidantes. Además, las especies pueden ser usadas como aditivos naturales en los alimentos, en cosmética y en industria farmacéutica

Supplementary data for the article: Zengin, G.; Cvetanović, A.; Gašić, U. M.; Stupar, A.; Bulut, G.; Şenkardes, I.; Dogan, A.; Ibrahime Sinan, K.; Uysal, S.; Aumeeruddy-Elalfi, Z.; Aktumsek, A.; Fawzi Mahomoodally, M. Modern and Traditional Extraction Techniques Affect Chemical Composition and Bioactivity of Tanacetum Parthenium (L.) Sch.Bip. Industrial Crops and Products 2020, 146. https://doi.org/10.1016/j.indcrop.2020.112202

Supplementary material for: [https://doi.org/10.1016/j.indcrop.2020.112202]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789/3882