296 research outputs found

    Okul Psikolojik Danışmanlarına Göre COVID-19 Pandemi Sürecinin Öğrenci, Öğretmen ve Velilere Etkileri

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    This study examines the positive and negative effects of the COVID-19 pandemic and distance education practices on students, teachers, and parents from the perspective of school counselors. This research was carried out within the scope of phenomenology design, a qualitative research method. The data were obtained via purposive sampling through online interviews conducted with 55 public school counselors at the end of the fall semester of the 2020-2021 academic year in Turkey. Content analysis was utilized to analyze the obtained data. The school counselors expressed that the pandemic had positive and negative relational, individual/psychological, and academic effects on students; positive and negative effects on the application of education and personal lives of teachers; and positive and negative effects on the parent–child–education relationship and the personal lives of parents. The results are discussed in relation to the relevant literature and recommendations are made.Okul psikolojik danışmanlarına göre COVID-19 pandemi süreci ve uzaktan eğitim uygulamalarının öğrenci, öğretmen ve velilere olumlu ve olumsuz yansımalarının incelendiği bu araştırma, nitel araştırma yöntemlerinden fenomenoloji deseni kapsamında yürütülmüştür. Araştırma verileri 2020-2021 eğitim-öğretim yılı güz dönemi sonunda, resmi okullarda görev yapmakta olan ve amaçlı örnekleme yöntemiyle belirlenen 55 okul psikolojik danışmanından çevrim içi görüşmeler aracılığıyla elde edilmiştir. Elde edilen verilerin çözümlenmesinde içerik analizi yöntemi kullanılmıştır. Okul psikolojik danışmanlarına göre pandemi sürecinin öğrenciler için; ilişkisel, bireysel/psikolojik ve akademik olarak olumlu katkıları ve olumsuz etkileri; öğretmenler için; eğitim-öğretimin işleyişine ve kişisel yaşantılarına yönelik olumlu katkıları ve olumsuz etkileri; veliler için ise ebeveyn-çocuk ve eğitim ilişkisine katkıları ve kişisel yaşantılarına yönelik olumlu katkıları ve olumsuz etkileri bulunmaktadır. Elde edilen sonuçlar literatür ışığında tartışılmış ve önerilerde bulunulmuştur

    Land-use dynamics associated with mangrove deforestation for aquaculture and the subsequent abandonment of ponds

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    Highlights SAR data is useful for tracking dynamic changes in mangrove ecosystem. Time series SAR data can be used to estimate lifespan of pond. During 22+ years, over half of the mangrove forest in Mahakam Delta has been converted to aquaculture. Abstract The objective of this study was to evaluate the spatiotemporal dynamics of large area mangrove deforestation, aquaculture pond building, and the subsequent abandonment of ponds in a large delta in Indonesia, namely the Mahakam Delta. So, we developed and applied a novel methodology for exploring the lifespan of aquaculture ponds. Using historical multispectral and radar data, the lifespans of aquaculture ponds across the delta were estimated via a chronological analysis of the landscape into four different states: primary mangroves → deforested mangroves → ponds → abandoned/inactive ponds. Specifically, a combination of sequential classification and rule-based techniques were used to: 1) produce a time series of land cover maps from 1994 to 2015 and 2) quantify lifespans of aquaculture ponds in the delta. Results show that of the 110,000 ha of primary mangrove forests in the delta in 1994, 62% had been deforested by 2015, with a 4.5% annual rate of loss on average. The lifespan of aquaculture ponds in the delta varied between 1 and 22+ years, with most of the ponds having productive lifespans of 10 to 13 years. Ponds with relatively longer lifespans were located near the existing settlements in the delta. This study showed that the productive lifespan of most aquaculture ponds in deforested mangrove lands of Mahakam delta is relatively short, information that should be useful for developing appropriate management plans for the delta or similar coastal mangrove ecosystems. The abandoned ponds can potentially be rehabilitated for shrimp and fish production after applying appropriate restorative treatments or be targeted for mangrove restoration projects

    Health-related Quality of Life of Cancer Caregivers in Klang Valley, Malaysia

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    Cancer caregiving has an impact on the quality of life (QOL) of the caregivers. This cross-sectional study determined the health-related QOL (HRQOL) of gastrointestinal cancer caregivers and associated factors across gender. A total of 323 respondents from major hospitals in Klang Valley completed HRQOL questionnaire from October 2017 to April 2018. Males had a better quality of life compared to females, mean HRQOL score 85.52 (SD=21.16) vs 77.66 (SD=21.36). The significant factors were: relationship between the caregiver and the patient; education level; employment status, marital status, household income and presence of disease. The gender role is vital for targeted intervention. Keywords: health-related quality of life; gastrointestinal cancer; caregivers; gender eISSN: 2398-4287© 2020. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia. DOI: https://doi.org/10.21834/ebpj.v5i15.245

    Evaluation of the anesthetic effects of xylazine-ketamine, xylazine-tiletamine-zolazepam and tiletamine-zolazepam using clinical and laboratory parameters in rabbits

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    The aim of this study was to evaluate the anesthetic effects of xylazine-ketamine (XK), xylazine-tiletamine-zolazepam (XTZ) and tiletamine-zolazepam (TZ) using hematological and biochemical parameters in rabbits. A total of 18 rabbits were divided into three equal treatment groups (n = 6). The rabbits in the XK, XTZ, and TZ groups were administered xylazine (5 mg/kg) and ketamine (50 mg/kg), xylazine (5 mg/kg) and TZ (15 mg/kg), and TZ (15 mg/kg), respectively, via the intramuscular route. Following the injection, their reflexes were tested every 5 minutes. Heart rate, respiratory rate, and body temperature were determined before the injection (0 min) and at 5, 15, 30, 45, 60, 75, 90, and 120 min after injecting the anesthetic combinations. Furthermore, hematological and biochemical (alanine transaminase [ALT], aspartate transaminase [AST], alkaline phosphatase [ALP], bilirubin, blood urea nitrogen [BUN], and urea) analyses were also performed before, during, and after anesthesia administration. The duration of anesthesia and loss of reflexes were significantly longer in the XTZ group than in the other groups. However, in the TZ group, reflexes were remained. Respiratory rate and body temperature decreased in all the groups. Moreover, heart rate reduced only in the XK and XTZ groups, and the hematological parameters of all groups were comparable. Serum AST and ALP levels increased in the XTZ group compared to that in the XK and TZ groups, respectively. However, these increases were within the reference limits. The post-anesthesia serum BUN and urea levels significantly increased in the XTZ group (p < 0.05) compared to that in the other groups. Thus, although the XTZ combination provided satisfactory anesthetic effect in rabbits, it may be nephrotoxic. Therefore, its use for anesthesia induction in invasive renal procedures and experimental nephrotoxicity studies is not advisable

    Optimization and analysis of surface roughness, flank wear and 5 different sensorial data via Tool Condition Monitoring System in turning of AISI 5140

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    Optimization of tool life is required to tune the machining parameters and achieve the desired surface roughness of the machined components in a wide range of engineering applications. There are many machining input variables which can influence surface roughness and tool life during any machining process, such as cutting speed, feed rate and depth of cut. These parameters can be optimized to reduce surface roughness and increase tool life. The present study investigates the optimization of five different sensorial criteria, additional to tool wear (VB) and surface roughness (Ra), via the Tool Condition Monitoring System (TCMS) for the first time in the open literature. Based on the Taguchi L9 orthogonal design principle, the basic machining parameters cutting speed (vc), feed rate (f) and depth of cut (ap) were adopted for the turning of AISI 5140 steel. For this purpose, an optimization approach was used implementing five different sensors, namely dynamometer, vibration, AE (Acoustic Emission), temperature and motor current sensors, to a lathe. In this context, VB, Ra and sensorial data were evaluated to observe the effects of machining parameters. After that, an RSM (Response Surface Methodology)-based optimization approach was applied to the measured variables. Cutting force (97.8%) represented the most reliable sensor data, followed by the AE (95.7%), temperature (92.9%), vibration (81.3%) and current (74.6%) sensors, respectively. RSM provided the optimum cutting conditions (at vc = 150 m/min, f = 0.09 mm/rev, ap = 1 mm) to obtain the best results for VB, Ra and the sensorial data, with a high success rate (82.5%)

    Molecular biological ınvestigation of the effect of Aloe vera on The Growth of Saccharomyces cerevisae

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    Aloe vera (A. vera) tropikal, kuraklığa dayanıklı bir sukulent bir bitkidir. A. vera bitkisi, çeşitli gıdalarda besin takviyesi olarak ve kozmetik ürünlerinde bir bileşen olarak kullanılmaktadır. Anti-inflamatuar, anti-kanser, anti-oksidan, anti-diyabetik ve yara iyileşmesi gibi biyolojik aktivitelere sahiptir. Bu yüzden çalışmamızda A. vera jelinin sisplatin (Cis) kaynaklı Saccharomyces cerevisiae (S.cerevisiae) kültüründe oksidatif hasar üzerindeki etkisi incelenmiştir. Çalışmamızdaki gruplarımız; Grup (1): Kontrol grubu; Grup (2): A. vera Grubu (%10); Grup (3): Cis Grubu (15 mM); Grup (4): A. vera (% 10) + Cis (15 mM) Grubu. Hücre gelişim ölçümleri, lipit peroksidasyonu malondialdehit (MDA) analizleri, glutatyon (GSH) seviyeleri ve katalaz (CAT) aktiviteleri spektrofotometre ile tespit edilmiştir. Total protein değişiklikleri SDS-PAGE elektroforezi ile belirlenmiş ve Bradford metodu ile hesaplanmıştır. Elde edilen sonuçlara göre; S.cerevisiae kültürlerine ilave edilen A. vera jel hücre gelişimini (1, 3, 5 ve 24 saat), total protein sentezini (24 saat), GSH seviyelerini (24 saat) ve CAT aktivitelerini (24 saat) arttırdığı, MDA düzeyini (24 saat) azalttığı tespit edilmiştir. Bu sonuçlar, A. vera jelinin S. cerevisiae kültüründe oksidatif hasarı azalttığını, protein sentezini teşvik ettiğini ve hücre büyümesini arttırmak için koruyucu bir etkiye sahip olduğunu göstermektedir.Aloe vera (A.vera) is a tropical, drought-resistant succulent plant. A. vera plant is used as a nutritional supplement in various foods and as an ingredient in cosmetic products. It has biological activities such as anti-inflammatory, anti-cancer, anti-oxidant, anti-diabetic and wound healing. Therefore, in our study, the effect of A. vera gel on oxidative damage in cisplatin (Cis)-derived Saccharomyces cerevisiae (S.cerevisiae) culture was investigated. Our groups in our study; Group (1): Control group; Group (2): A. vera Group (10%); Group (3): Cis Group (15 mM); Group (4): A. vera (10%) + Cis (15 mM) Group. Cell growth measurements, lipid peroxidation, malondialdehyde (MDA) analysis, glutathione (GSH) levels and catalase (CAT) activities were defined by spectrophotometer. Total protein varies were determined by SDS-PAGE electrophoresis and computed by the Bradford method. According to the conclusions obtained, A. vera gel added to S.cerevisiae cultures increased cell development (1, 3, 5 and 24 hours), total protein synthesis (24 hours), GSH levels (24 hours) and CAT activities (24 hours) it has been found to reduce the MDA level (24 hours). These conclusions indicate that A. vera gel decrease oxidative damage in S. cerevisiae culture, promotes protein synthesis and has a protecting effect to increase cell development

    ANTI-OXIDANT EFFECTS OF POMEGRANATE JUICE ON SACCHAROMYCES CEREVISIAE CELL GROWTH

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    Background: Pomegranate juice has a number of positive effects on both human and animal subjects. Material and methods: Four groups were used in this study. i: Control group, ii: H 2 O 2 group, iii: Pomegranate juice (PJ) group and iv: PJ + H 2 O 2 group. Following the sterilization method for pomegranate juice (10%) and H 2 O 2 (6% v/v), Saccharomyces cerevisiae cultures were added and the cultivation incubated at 35°C for 72 hours. Fatty acids and vitamin concentrations were measured using HPLC and GC and the total protein bands profile were determined by SDS-PAGE. Results: According to our results statistically significant differences have been determined among the study groups in terms of fatty acids and vitamin (

    Different epidemiology of bloodstream infections in COVID-19 compared to non-COVID-19 critically ill patients: a descriptive analysis of the Eurobact II study

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    Bloodstream infection; COVID-19; EnterococcusInfección del torrente sanguíneo; COVID-19; EnterococoInfecció del torrent sanguini; COVID-19; EnterococBackground The study aimed to describe the epidemiology and outcomes of hospital-acquired bloodstream infections (HABSIs) between COVID-19 and non-COVID-19 critically ill patients. Methods We used data from the Eurobact II study, a prospective observational multicontinental cohort study on HABSI treated in ICU. For the current analysis, we selected centers that included both COVID-19 and non-COVID-19 critically ill patients. We performed descriptive statistics between COVID-19 and non-COVID-19 in terms of patients’ characteristics, source of infection and microorganism distribution. We studied the association between COVID-19 status and mortality using multivariable fragility Cox models. Results A total of 53 centers from 19 countries over the 5 continents were eligible. Overall, 829 patients (median age 65 years [IQR 55; 74]; male, n = 538 [64.9%]) were treated for a HABSI. Included patients comprised 252 (30.4%) COVID-19 and 577 (69.6%) non-COVID-19 patients. The time interval between hospital admission and HABSI was similar between both groups. Respiratory sources (40.1 vs. 26.0%, p < 0.0001) and primary HABSI (25.4% vs. 17.2%, p = 0.006) were more frequent in COVID-19 patients. COVID-19 patients had more often enterococcal (20.5% vs. 9%) and Acinetobacter spp. (18.8% vs. 13.6%) HABSIs. Bacteremic COVID-19 patients had an increased mortality hazard ratio (HR) versus non-COVID-19 patients (HR 1.91, 95% CI 1.49–2.45). Conclusions We showed that the epidemiology of HABSI differed between COVID-19 and non-COVID-19 patients. Enterococcal HABSI predominated in COVID-19 patients. COVID-19 patients with HABSI had elevated risk of mortality. Trial registration ClinicalTrials.org number NCT03937245. Registered 3 May 2019.Research grants were obtained from the European society of Intensive Care Medicine (ESICM) and the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) study Group for Infections in Critically Ill Patients (ESGCIP), the Norva Dahlia foundation and the Redcliffe Hospital Private Practice Trust Fund. Dr. Buetti received a grant from the Swiss National Science Foundation (Grant Number: P4P4PM_194449). The study was endorsed by the critically ill group of the ESCMID (ESGCIP) and by the infection group of the ESICM with scientific input of the OUTCOMEREA network

    Association between aortic stiffness and left ventricular function in inflammatory bowel disease

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    Background: Recent studies have reported an increased incidence of both aortic stiffness and left ventricular (LV) systolic and diastolic dysfunction in patients with inflammatory bowel disease (IBD). However, the association between aortic stiffness and the LV function has not been fully defined. We aimed to investigate the relationship between aortic stiffness and the LV function in IBD patients. Methods and Results: Seventy-two patients with IBD (56 cases of ulcerative colitis and 16 cases of Crohn’s disease) and 50 healthy controls were consecutively enrolled in this study. The LV systolic and diastolic functions were assessed using conventional echocardiographic techniques, including tissue Doppler echocardiography. The degree of aortic strain and distensibility were calculated based on the aortic diameters measured on M-mode echocardiography at the level of 3 cm above the aortic valve and the blood pressure values obtained on sphygmomanometry. There were significant differences between the IBD and control group in the degree of aortic strain and distensibility. Significant differences were also observed between the patient and control groups in the parameters of the LV systolic and diastolic functions. Moreover, aortic stiffness was found to be associated with the LV function in the patient group. Conclusions: There is a significant relationship between aortic stiffness and LV systolic and diastolic dysfunction in patients with IBD, based on the findings of this study. The parameters of aortic elasticity measured according to 2-dimensional echocardiographic methods can be beneficial for predicting early cardiovascular risk in cases of IBD. (
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