10 research outputs found
Global economic burden of unmet surgical need for appendicitis
- Author
- Aahlin E. K.
- Aamer A.
- Aaniana K.
- Ababneh A.
- Abaliksta T.
- Abantanga F.
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- Publication venue
- Oxford University Press
- Publication date
- 01/01/2022
- Field of study
Background: There is a substantial gap in provision of adequate surgical care in many low-and middle-income countries. This study aimed to identify the economic burden of unmet surgical need for the common condition of appendicitis. Methods: Data on the incidence of appendicitis from 170 countries and two different approaches were used to estimate numbers of patients who do not receive surgery: as a fixed proportion of the total unmet surgical need per country (approach 1); and based on country income status (approach 2). Indirect costs with current levels of access and local quality, and those if quality were at the standards of high-income countries, were estimated. A human capital approach was applied, focusing on the economic burden resulting from premature death and absenteeism. Results: Excess mortality was 4185 per 100 000 cases of appendicitis using approach 1 and 3448 per 100 000 using approach 2. The economic burden of continuing current levels of access and local quality was US 92492millionusingapproach1and73 141 million using approach 2. The economic burden of not providing surgical care to the standards of high-income countries was 95004millionusingapproach1and75 666 million using approach 2. The largest share of these costs resulted from premature death (97.7 per cent) and lack of access (97.0 per cent) in contrast to lack of quality. Conclusion: For a comparatively non-complex emergency condition such as appendicitis, increasing access to care should be prioritized. Although improving quality of care should not be neglected, increasing provision of care at current standards could reduce societal costs substantially
Global variation in anastomosis and end colostomy formation following left-sided colorectal resection
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- Baheeg M
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- Baillie K
- Baillie K
- Baird A
- Bakhaidar M
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- Bakr A
- Bakry Hm
- Baky Fahmy MA
- Bala M
- Balalis D
- Baldacchino M
- Balducci G
- Balila Rmh
- Balkan Aza
- Ballouhey Q
- Balmaceda R
- Balmaceda R
- Balmaceda R
- Balogun F
- Baltrunas R
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- Bamford R
- Bamicha A
- Bamicha A
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- Bandi A
- Bandoh D
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- Baraka H
- Barakat Sae
- Barendegere V
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- Barkolias C
- Barmayehvar B
- Barnabas Gn
- Barnacle J
- Barneo L
- Barrantes Ams
- Barreda Lma
- Barrientos Lam
- Barrios E
- Barrios E
- Barrios E
- Barry J
- Basilicò
- Basir Erm
- Bassem M
- Bassit Ka
- Basso Sm
- Basson S
- Basto Caa
- Batt J
- Bautista Acm
- Bautista Acm
- Bayram S
- Beamon M
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- Beaton C
- Bedada Ag
- Bediako-Bowan A
- Behar N
- Beisa V
- Beisa V
- Bekhet Ah
- Bekhet Nm
- Beleñ
- Belkouchi A
- Belli A
- Bello B
- Benammi S
- Benevento A
- Benevento A
- Benger M
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- Benons N
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- Benyaiche C
- Bermú
- Bernardo Cg
- Berti S
- Bertuello I
- Beuran M
- Beuran M
- Beyene R
- Bezzina M
- Bhangu A
- Bhangu A
- Bhangu A
- Bhangu A
- Bhargava A
- Bharj Is
- Bhat S
- Bhatnagar A
- Bhattacharya S
- Bhopal Kf
- Bhopal Kf
- Bianco F
- Bigaran A
- Billy M
- Birindelli A
- Birring A
- Bisset C
- Bjö
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- Blacker S
- Blackwell J
- Blanco R
- Blanco-Colino R
- Blencowe N
- Blencowe N
- Bliksø
- Blower E
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- Blundell R
- Boakye-Yiadom K
- Boal M
- Bocchetti T
- Boddy A
- Bode C
- Bode C
- Bodur S
- Boereboom C
- Boggon A
- Boijsen M
- Bokhari S
- Bonavia K
- Bonavina L
- Bonavina L
- Bond-Smith G
- Bondin J
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- Bondurri A
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- Borg E
- Borin E
- Bortolasi L
- Bortolasi L
- Boshnaq M
- Botero Jam
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- Botto N
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- Bougard H
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- Bowe R
- Bowley D
- Bowling K
- Bowman C
- Boyce T
- Bré
- Bradulskis S
- Bradulskis S
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- Bratu Rm
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- Bray Ld
- Breistrand M
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- Broch A
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- Brown E
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- Brown J
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- Bukari M
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- Bustangi N
- Butt Mt
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- Carabott K
- Cardozo Jt
- Cardozo Ram
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- Carlucci M
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- Cassar K
- Castillo Vdp
- Castro Mr
- Catani M
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- Chachulski W
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- Chai Fy
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- Chan Z
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- Chang Ky
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- Chetta N
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- Chin Yr
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- Chiong Jac
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- Chong Hy
- Chong Hy
- Choudhry A
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- Chun T
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- Chung S
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- Clegg-Lampety Jn
- Clegg-Lamptey Jn
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- Corbellini C
- Corbellino M
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- Costa-Maia J
- Costa-Maia J
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- D&apos
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- D&apos
- Da Silva LA
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- Dambrauskas Z
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- Dasari M
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- Dawnay G
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- Dawoud H
- Dayie M
- De Boni D
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- De La Medina AR
- de Leó
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- Dell A
- Dempster E
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- Depalma N
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- Der Y
- Dervenis C
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- Deutschmann P
- Devadasar Gh
- Dharamshi Ha
- Dhillon D
- Di Franco F
- Di Martino N
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- Di Saverio S
- Diab A
- Diaconescu B
- Diaconescu Ib
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- Dick L
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- Domini E
- Donnelly P
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- Dorismé
- Dos Santos DV
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- Drake Tm
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- Duffy L
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- El Sayed IM
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- El-Ma&apos
- El-Rabaa S
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- El-Shahat Ns
- El-Sheemy H
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- Elabdin Hz
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- Elazayem Aa
- Elazoul M
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- Elbatahgy A
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- Eldin Mab
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- Elfeki H
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- Elkorashy Am
- Ellison Q
- Elmashala A
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- Elrasoul Ya
- Elrazek Aa
- Elsabbagh N
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- Elsawahly Dme
- Elsawy A
- Elsayed M
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- Elsehimy M
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- Elshaer M
- Elshafay Ae
- Elshami M
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- Elshobary M
- Elsiddig M
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- Elwaey A
- Elwakil H
- Elwan A
- Elwan A
- Elwy E
- Elzahed N
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- Elzayat M
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- Emadeldin D
- Emadeldin H
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- Emile S
- Eng C
- English W
- Esam A
- Escobar Eg.
- Espin-Basany E
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- Espinoza Kt
- Essam A
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- Essam M
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- Estupinian S
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- Etchill E
- Etienne S
- Etman M
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- Evans E
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- Ezzat T
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- Fahiem A
- Fahim M
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- Fairfield C
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- Fairfield C
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- Farahat Mm
- Faraz A
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- Farhan-Alanie Mmh
- Farhangmehr N
- Farinella E
- Farmakis K
- Farooq T
- Farouk Sam
- Farquharson A
- Farrugia A
- Farrugia A
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- Fathy Am
- Fattah Aa
- Fatuga A
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- Faturoti O
- Faure A
- Fautz T
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- Fawzy A
- Feidantsis T
- Felipe Co
- Fergany A
- Fergusson Sj
- Fergusson Sj
- Fergusson Sj
- Fermani C
- Fermani Cg
- Ferná
- Fernandes C
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- Ferousis C
- Ferreira Sak
- Ferrero E
- Fievet L
- Filatau A
- Findlay-Cooper K
- Firdouse M
- Firdouse M
- Firdouse M
- Firwana A
- Fitsum A
- Fitzgerald Je
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- Foco M
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- Foo Cc
- Forlin L
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- Fouad D
- Fourcade L
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- Fozard T
- Frade F
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- Francois-Coridon H
- Francone E
- Freitas Av
- Frey D
- Frisk B
- Fuentes-Rivera L
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- Gad A
- Gad Mo
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- Gaiž
- Gaignard E
- Gaignard E
- Gala T
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- Galiqi G
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- Gallo G
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- Gamal D
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- Gamal H
- Gamal S
- Gamaly E
- Gamil D
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- Gani Ma
- Garaycochea O
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- Garcia-Marin Ja
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- Gemeah M
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- George R
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- Gerosa A
- Gerosa A
- Geuoshy A
- Ghaben A
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- Ghannam M
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- Ghetia M
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- Giuriato Tf
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- Grizhja B
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- Grosos C
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- Gudal A
- Gudal A
- Gudal A
- Gudlaugsdottir K
- Guevara R
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- Gui D
- Gulbinas A
- Gulcicek Ob
- Gulielmi A
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- Gunnarsson U
- Guo W
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- Gustafsson U
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- Gyedu A
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- Habeeb O
- Habeebullah A
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- Haddad N
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- Hafiz S
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- Hajeh H
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- Halhouli O
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- Halicioglu I
- Hall E
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- Hamaguchi Jlh
- Hamarshi A
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- Hamdan A
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- Hany E
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- Hasheminia A
- Hashim A
- Hashish A
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- Hasnan Mb
- Hassaan A
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- Hassan A
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- Hassan Ata
- Hassan I
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- Hassan Omm
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- Hassan Z
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- Hassanein Ab
- Havemann I
- Hawkins W
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- Helguero-Santin Lm
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- Hemmila M
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- Herebat A
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- Hoogakker E
- Horobjowsky A
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- Hossameldin A
- Houlden C
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- Hutch W
- Huwait A
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- Iacono C
- Iannone I
- Ibraheem Aa
- Ibraheem Hi
- Ibrahem Aa
- Ibrahem Aa
- Ibrahim A
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- Ibrahim A
- Ibrahim Am
- Ibrahim E
- Ibrahim Em
- Ibrahim I
- Ibrahim K
- Ibrahim M
- Ibrahim Mh
- Ibrahim Y
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- Idris F
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- Iftekhar F
- Iftikhar Z
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- Ihediwa G
- Imoro O
- Ingabire Jca
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- Ioannidis O
- Iordache Fm
- Iqbal Fm
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- Ireland P
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- Irwin G
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- Israelsson L
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- Jabbar A
- Jaber S
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- Jaramillo Ra
- Jarmin M
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- Javed O
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- Jayathilake Ab
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- Kabariti R
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- Kabba J
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- Kache S
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- Kalles V
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- Karousos D
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- Kasem E
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- Kasputyte S
- Kaul A
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- Kennedy Ed
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- Khedr Aeh
- Khg Li
- Khoja A
- Khoja A
- Khokha D
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- Khosla S
- Khreishi R
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- Khulu Lb
- Khyrallh A
- Kiasat A
- Kidd T
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- Kim My
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- King R
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- Klappenbach R
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- Komolafe O
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- Kong C
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- Koskenvuo L
- Kostov E
- Kotb Ahe
- Kotecha D
- Koto Mz
- Kotobi H
- Koumpa F
- Kouraklis G
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- Kwakyeafriyie P
- Kwatiwani C
- Kwizera S
- Kwok Sh
- Kyereh M
- Kyriazanos I
- Kyrou G
- Kyziridis D
- Ló
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- La Brocca A
- la Medina AR
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- Labib P
- Ladukas A
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- Landolfo G
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- Latif A
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- Laugzemys E
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- Laurie K
- Lauzikas G
- Law Jh
- Lawal A
- Lawal Ao
- Lawal T
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- Lawani I
- Lawther R
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- Leal A
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- Lee C
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- Lee F
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- Leone N
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- Leusink A
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- Loaloa Mr
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- Macchitella Y
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- Macfarlane A
- Machaca M
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- Margaritis M
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- Marinkovic B
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- Marks E
- Marples L
- Marret Jb
- Marshall Dc
- Martian Bv
- Martin A
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- Miranda C
- Mircea H
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- Mironescu A
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- Mirza A
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- Mistry A
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- Mohamed F
- Mohamed I
- Mohamed M
- Mohamed Ma
- Mohamed Maeh
- Mohamed Mm
- Mohamed O
- Mohamed Sr
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- Mohammad A
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- Montejo Msg
- Monteleone M
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- Montes I
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- Montrimaite M
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- Moodley Y
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- Mostafa Ha
- Mostafa M
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- Moustafa A
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- Mowafy B
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- Mshelbwala P
- Msiska N
- Msosa V
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- Mukuzunga C
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- Nanthakumaran S
- Napolitano L
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- Naranjo Aristizã
- Narayanan R
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- Negida A
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- Nepogodiev D
- Nepogodiev D
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- Nesaratnam A
- Nessa A
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- Nevieraite V
- Newton T
- Ng S
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- Njokanma I
- Nnajiuba H
- Nocito A
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- Noor F
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- Nouh T
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- Noukpozounkou B
- Novak A
- Nowers J
- Nsengimana Vjp
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- Ntirenganya F
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- Nurqistan Hd
- Nwabuoku E
- Nwinee V
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- Redota Map
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- Runigamugabo E
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- Salama M
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- Sallinen V
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- Salma M
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- Samaniego Cs
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- Schiavone R
- Schivo D
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- Senanayake Kj
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- Septiem Jg
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- Sfougaris D
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- Shahbaz Ar
- Shaheen A
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- Shahzad N
- Shaikh N
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- Publication venue
- 'Wiley'
- Publication date
- 27/11/2018
- Field of study
Background
End colostomy rates following colorectal resection vary across institutions in high-income settings, being influenced by patient, disease, surgeon and system factors. This study aimed to assess global variation in end colostomy rates after left-sided colorectal resection.
Methods
This study comprised an analysis of GlobalSurg-1 and -2 international, prospective, observational cohort studies (2014, 2016), including consecutive adult patients undergoing elective or emergency left-sided colorectal resection within discrete 2-week windows. Countries were grouped into high-, middle- and low-income tertiles according to the United Nations Human Development Index (HDI). Factors associated with colostomy formation versus primary anastomosis were explored using a multilevel, multivariable logistic regression model.
Results
In total, 1635 patients from 242 hospitals in 57 countries undergoing left-sided colorectal resection were included: 113 (6·9 per cent) from low-HDI, 254 (15·5 per cent) from middle-HDI and 1268 (77·6 per cent) from high-HDI countries. There was a higher proportion of patients with perforated disease (57·5, 40·9 and 35·4 per cent; P < 0·001) and subsequent use of end colostomy (52·2, 24·8 and 18·9 per cent; P < 0·001) in low- compared with middle- and high-HDI settings. The association with colostomy use in low-HDI settings persisted (odds ratio (OR) 3·20, 95 per cent c.i. 1·35 to 7·57; P = 0·008) after risk adjustment for malignant disease (OR 2·34, 1·65 to 3·32; P < 0·001), emergency surgery (OR 4·08, 2·73 to 6·10; P < 0·001), time to operation at least 48 h (OR 1·99, 1·28 to 3·09; P = 0·002) and disease perforation (OR 4·00, 2·81 to 5·69; P < 0·001).
Conclusion
Global differences existed in the proportion of patients receiving end stomas after left-sided colorectal resection based on income, which went beyond case mix alone
Crystal structure and Hirshfeld surface analysis of ethyl (3E)-5-(4-fluorophenyl)3-{[(4-methoxyphenyl)formamido]imino}-7-methyl-2H,3H,5H-[1,3]-thiazolo[3,2-a]pyrimidine-6-carboxylate 0.25-hydrate
- Author
- Publication venue
- 'International Union of Crystallography (IUCr)'
- Publication date
- 09/08/2022
- Field of study
In the title compound, C24H23FN4O4S center dot 0.25H(2)O, the dihydropyrimidine ring is distinctly non-planar, with the flap C atom deviating by 0.297 (2) angstrom from the least-squares plane. In the crystal, zigzag chains are formed by N-H center dot center dot center dot N hydrogen bonds parallel to [010] and are connected into layers parallel to (100) by O-H center dot center dot center dot O, O-H center dot center dot center dot F, C-H center dot center dot center dot O, C-H center dot center dot center dot F and C-H center dot center dot center dot N hydrogen bonds. Additional C-H center dot center dot center dot O hydrogen bonds connect the layers into a three-dimensional network. A Hirshfeld surface analysis indicates that the most significant contributions to the crystal packing are from H center dot center dot center dot H (42.6%), O center dot center dot center dot H/H center dot center dot center dot O (16.8%) and C center dot center dot center dot H/H center dot center dot center dot C (15.5%) contacts
Efficient synthesis of some novel furo[3,2-<i>e</i>]pyrazolo[3,4-<i>b</i>]pyrazines and related heterocycles
- Author
- Publication venue
- Publication date
- Field of study
<p>A series of novel 6-functionalized-5-amino-3-methyl-1-phenyl-1<i>H</i>-furo[3,2-<i>e</i>]pyrazolo[3,4-<i>b</i>]pyrazines <b>(4a–c)</b> was synthesized by the reaction of 3-methyl-6-oxo-1-phenyl-6,7-dihydro-1<i>H</i>-pyrazolo[3,4-<i>b</i>]pyrazine-5-carbonitrile <b>(2)</b> with α-halocarbonyl compounds such as: diethyl 2-bromomalonate, phenacyl bromide and chloroacetone. Cyclocondensation of the amino benzoyl <b>4b</b> with diethyl malonate yielded the oxopyridine carboxylate derivative <b>5</b>. Also, the starting intermediate amino ester compound <b>4a</b> was allowed to react with ethanol amine to afford the hydroxyethyl caboxamide derivative <b>6</b>. Furthermore, hydrazinolysis of the amino ester <b>4a</b> afforded the corresponding amino carbohydrazide <b>7</b> which was used as a versatile precursor for synthesis of other heterocyclic compounds attached or fused to the furopyrazolopyrazine moiety. The chemical structures of the newly synthesized compounds were confirmed on the basis of elemental and spectral analyses containing FT-IR, <sup>1</sup>H NMR, <sup>13</sup>C NMR, and mass spectrometry hoping these molecules should allow us to investigate their pharmacological activities in the future study.</p
Crystal structure and Hirshfeld surface analysis of ethyl (3E)-5-(4-chlorophenyl)-3-{[(4-chlorophenyl)formamido]imino}-7-methyl-2H,3H,5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
- Author
- Publication venue
- 'International Union of Crystallography (IUCr)'
- Publication date
- 26/07/2022
- Field of study
In the title molecule, C23H20Cl2N4O3S, the thiazole ring is planar while the pyrimidine unit fused to it adopts a screw-boat conformation. In the crystal, thick sheets parallel to the bc plane are formed by N-H center dot center dot center dot N, C-H center dot center dot center dot N and C-H center dot center dot center dot O hydrogen bonds together with pi-pi interactions between the formamido carbonyl groups and the thiazole rings. Hirshfeld surface analysis indicates that the most important contributions to the crystal packing are from H center dot center dot center dot H (30.9%), Cl center dot center dot center dot H/H center dot center dot center dot Cl (20.7%), C center dot center dot center dot H/H center dot center dot center dot C (16.8%) and O center dot center dot center dot H/H center dot center dot center dot O (11.4%) interactions
Efficient synthesis of some novel furo[3,2- e
- Author
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Global variation in anastomosis and end colostomy formation following left-sided colorectal resection
- Author
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- Zulkifli A.
- Zumbuhl L.
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2019
- Field of study
Background: End colostomy rates following colorectal resection vary across institutions in high-income settings, being influenced by patient, disease, surgeon and system factors. This study aimed to assess global variation in end colostomy rates after left-sided colorectal resection. Methods: This study comprised an analysis of GlobalSurg-1 and-2 international, prospective, observational cohort studies (2014, 2016), including consecutive adult patients undergoing elective or emergency left-sided colorectal resection within discrete 2-week windows. Countries were grouped into high-, middle-and low-income tertiles according to the United Nations Human Development Index (HDI). Factors associated with colostomy formation versus primary anastomosis were explored using a multilevel, multivariable logistic regression model. Results: In total, 1635 patients from 242 hospitals in 57 countries undergoing left-sided colorectal resection were included: 113 (6·9 per cent) from low-HDI, 254 (15·5 per cent) from middle-HDI and 1268 (77·6 percent) from high-HDI countries. There was a higher proportion of patients with perforated disease (57·5, 40·9 and 35·4 per cent; P < 0·001) and subsequent use of end colostomy (52·2, 24·8 and 18·9 per cent; P < 0·001) in low-compared with middle-and high-HDI settings. The association with colostomy use in low-HDI settings persisted (odds ratio (OR) 3·20, 95 per cent c.i. 1·35 to 7·57; P = 0·008) after risk adjustment for malignant disease (OR 2·34, 1·65 to 3·32; P < 0·001), emergency surgery (OR 4·08, 2·73 to 6·10; P < 0·001), time to operation at least 48 h (OR 1·99, 1·28 to 3·09; P = 0·002) and disease perforation (OR 4·00, 2·81 to 5·69; P < 0·001). Conclusion: Global differences existed in the proportion of patients receiving end stomas after left-sided colorectal resection based on income, which went beyond case mix alone
Global economic burden of unmet surgical need for appendicitis
- Author
- A A Essam
- Abd El-Rahman Hegazy Khedr
- Abd Elkhalek Sallam
- Abd Elrahman Elshafay
- Abdalla Gamal Saad
- Abdalla Gharib
- Abdalla Kenibar
- Abdallah Salah Elsherbiny
- Abdalrahman Adel
- Abdelaziz Abdelaal
- Abdelaziz Osman Abdelaziz Elhendawy
- Abdelfatah Hussein
- Abdelkader Belkouchi
- Abdelmalek Hrora
- Abdelrahman Adelshone
- Abdelrahman Alkammash
- Abdelrahman Assal
- Abdelrahman Geuoshy
- Abdelrahman Haroun
- Abdelrahman Mohammed
- Abdelrahman Sayed
- Abdelrahman Soliman
- Abdelrhman Essam Elnemr
- Abdelrhman Kz Darwish
- Abdelrhman Osama Elsebaaye
- Abdul Khalique
- Abdul Rehman Alvi
- Abdul Wahid Anwar
- Abdulaziz Altwijri
- Abdullah Al-Mallah
- Abdullah Almoflihi
- Abdullah Altamimi
- Abdullah Daqeeq
- Abdullah Dwydar
- Abdullah Gouda
- Abdullah Hashim
- Abdulmalik Altaf
- Abdulmalik Huwait
- Abdulrahman Abdel-Aty
- Abdulrahman M Altwigry
- Abdulrahman Sheshe
- Abdulrasheed A Nasir
- AbdulRazzaq Oluwagbemiga Lawal
- Abdulshafi Khaled Abdrabou
- Abdurrahaman Sheshe
- Abdussemiu Abdurrazzaaq
- Abebe Bekele Zerihun
- Abeer Al-Shammari
- Abeer El Gendy
- Abeer Esam
- Abeer Marey
- Abhishek Mittal
- Abiboye Yifieyeh
- Abid Bin Mahamood
- Abidemi Adesuyi
- Abouelatta Khairy Aly
- Abrar Nawawi
- Adam Gyedu
- Ade Waterman
- Adedapo Osinowo
- Adedeji Fatuga
- Adel Albiety
- Adel B Hassanein
- Adel Denewar
- Adeleke Adekoya
- Ademola Adebanjo
- Ademola Adeyeye
- Ademola Popoola
- Adesina Adedeji
- Adesoji O Ademuyiwa
- Adesoji Tade
- Adewale Adeniyi
- Adewale O Adisa
- Adham Tarek
- Adomas Ladukas
- Adrian F Palma
- Afifatun Hasanah
- Afizah Salleh
- Afnan Abdelfatah
- Afnan Altamimi
- Afnan Altamini
- Agazi Fitsum
- Agboola Taiwo
- Ahamed Hassan
- Ahed Ghaben
- Ahmad Abdel Fattah
- Ahmad Abdel Razaq Al Rafati
- Ahmad Aboelkassem Ibrahem
- Ahmad Aldalaq
- Ahmad Ali
- Ahmad Almallah
- Ahmad Alrifaie
- Ahmad Ashour
- Ahmad Bakr
- Ahmad Bani-Sadar
- Ahmad Bin Adnan
- Ahmad Elbatahgy
- Ahmad Faraz
- Ahmad Gudal
- Ahmad Hasan
- Ahmad Khaled Sabe
- Ahmad Khoja
- Ahmad Nashaat
- Ahmad Qaissieh
- Ahmad Sabe
- Ahmad Saber Sleem
- Ahmad Sakr
- Ahmad Shalabi
- Ahmad Uzair Qureshi
- Ahmed Aamer
- Ahmed Abd El Galeel
- Ahmed Abd Elmoen Elhusseiny
- Ahmed Abd Elsameea
- Ahmed Abdelkareem
- Ahmed Abdelmotaleb Ghazy
- Ahmed Abo El Magd
- Ahmed Abo Elazayem
- Ahmed Adamu
- Ahmed Adel
- Ahmed Afandy
- Ahmed Ahmed
- Ahmed Al-Khatib
- Ahmed Alghamdi
- Ahmed Ali
- Ahmed Altibi
- Ahmed Alzahrani
- Ahmed Ata
- Ahmed Badr
- Ahmed Dahy
- Ahmed Diab
- Ahmed El Kashash
- Ahmed El Kholy
- Ahmed El-Sehily
- Ahmed Elgaili Khalid Musa
- Ahmed Elgebaly
- Ahmed Elkelany
- Ahmed Elkholy
- Ahmed Essam
- Ahmed Fahiem
- Ahmed Farag
- Ahmed Fawzy
- Ahmed Fouad
- Ahmed Gad
- Ahmed Ghanem
- Ahmed Gheith
- Ahmed Gomaa
- Ahmed Hafez El-Badri Kotb
- Ahmed Hammad
- Ahmed Hassan
- Ahmed Hossam Eldin Fouad Rida
- Ahmed Ismail
- Ahmed Karim
- Ahmed Khyrallh
- Ahmed Lasheen
- Ahmed M Rashed
- Ahmed Magdy
- Ahmed Mahmoud Abdelraouf
- Ahmed Menshawy
- Ahmed Meshref
- Ahmed Mohamed Afifi
- Ahmed Mohamed Ibrahim
- Ahmed Mohameden
- Ahmed Mohammed
- Ahmed Mokhtar
- Ahmed Mosad
- Ahmed Moustafa
- Ahmed Moustafa Saeed
- Ahmed Negida
- Ahmed Rabeih Mohammed
- Ahmed Rabie Mohamed
- Ahmed Ragab Nayel
- Ahmed Ragab Soliman
- Ahmed Raslan
- Ahmed Raza
- Ahmed Refaat
- Ahmed Rslan
- Ahmed Sabry
- Ahmed Sabry El-Hamouly
- Ahmed Safwan Marey
- Ahmed Saidbadr
- Ahmed Sakr
- Ahmed Samir
- Ahmed Shahine
- Ahmed Sheta
- Ahmed Soliman
- Ahmed Tammam
- Ahmed Tarek Abdelbaset Hassan
- Ahmed W Shamsedine
- Ahmed Zaki
- Ahmed Zaki Eldeeb
- Ahmed Zohair
- Ahmedali M Kandil
- Ahmedglal Elnagar
- Ahsan Zil-E-Ali
- Aijaz Jabbar
- Ailsa Claire Snaith
- Ainhoa Costas-Chavarri
- Aiste Austraite
- Ajayesh Mistry
- Akin Olaolorun
- Akinlabi E Ajao
- Al Faifi Jubran
- Ala Shamasneh
- Alaa Abouelnasr
- Alaa Al-Buhaisi
- Alaa Bowabsak
- Alaa El Jamassi
- Alaa Elazab
- Alaa Elhadad
- Alaa Fergany
- Alaa Habeebullah
- Alaa Hassan
- Alaa Shabkah
- Alaa Shaheen
- Alaba Adesina
- Alan Baird
- Alan Grant
- Alasdair Ball
- Alban Cacurri
- Albert Mohale Mphatsoe
- Alberto Realis Luc
- Alejandro Matheu
- Alejandro Munera
- Alemayehu Ginbo Bedada
- Alessandro Favero
- Alessio Maniscalco
- Alexander Canta Calua
- Alexander J Fowler
- Alexandra Gerosa
- Alexandre Horobjowsky
- Alexandre Venancio De Sousa
- Alexia Farrugia
- Alexis Pierre Arnaud
- Alfio Alessandro Russo
- Alfredo Gulielmi
- Ali Ababneh
- Ali Abo El Dahab
- Ali Amin Ahmed Ata
- Ali Khan Niazi
- Ali Kiasat
- Ali Mohamed Hammad
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- Shereen Elsheikh
- Sherif Shehata
- Sherif Tariq
- Shimaa Gamal
- Shimaa Said Elkholy
- Shireen Gaafar
- Shirish Tewari
- Shiva Dindyal
- Shivanee Tharmalingam
- Shorouk El Mesery
- Shpetim Ymeri
- Shravan Nadkarni
- Shruti Ayyar
- Shu Ning Kong
- Shuang Yi Teo
- Shyam Gokani
- Shyang Yee Lim
- Silje Holte
- Silvia Basilicò
- Silvia Boni
- Silvia De Franciscis
- Simon George Gosling
- Simon Gosling
- Simon Ng
- Simon Stock
- Simona Juciute
- Simona Kasputyte
- Simone Conci
- Simone Sandler
- Simone Targa
- Sir Young Yam
- Siti Mohd Desa Asilah
- Siti Nur Alia Kamarulzamil
- Sivasuriya Sivaganesh
- Siyaka Itopa Suleiman
- Siyi Chung
- Soaad Elsobky
- Sofia Mouttalib
- Soha Abushamleh
- Sohaila Elmihy
- Soliman Magdy Ahmed
- Sondos Turkustani
- Sophian Hmila
- South Africa
- Srinivas Pai
- Sriram Bhat
- Stassen Paul
- Stavros Parasyris
- Stefan Botes
- Stefan Breitenstein
- Stefan Zammit
- Stefano Berti
- Stefano Cucumazzo
- Stefano M M Basso
- Stefano Roncali
- Stella Binna Kim
- Sten Saar
- Stephanie Hiu-Wai Kwok
- Stephanie Van Straten
- Stephen Dias
- Stephen J Chapman
- Stephen Kache
- Stephen Mcaleer
- Stephen R Knight
- Stephen Tabiri
- Steponas Petrikenas
- Stuart J Fergusson
- Styliani Parpoudi
- Stylianos Germanos
- Sudipta Roy
- Sukrit Suresh
- Sule Burger
- Suleiman Baba
- Sultan Almuallem
- Sung-Hee Kim
- Sunil Kumar
- Suparna Das
- Suraya Bahar
- Susan Aviles
- Susan Limache
- Susan Wndy Mathew
- Susana Yrma Aranzabal Durand
- Svetlana Doris Brincat
- Swantje Kruspi
- Swapnil Roy
- Syed Abdul Wahhab Eusoffee Wan Ali
- Syed Altaf Naqvi
- Syed Asaat Ul Razi
- Sylvia Batista Lemaire
- Sylvie Mochet
- Syrine Rekhis
- T Ariani Widiastini
- Tagang Ebogo Ngwa
- Taha Yusufali
- Taher Al-Taher
- Tahir Muhammad Yaseen
- Tahir Yaseen
- Tahira Naqvi
- Taiwo Akeem Lawal
- Taiwo Lawal
- Tan Arulampalam
- Tanzeela Gala
- Tapan Kumar
- Tara Grima
- Tarek Ezzat
- Tarek Razek
- Tasneem Idress
- Tasnia Hamid Kanta
- Tatsiana Shachykava
- Taufiq Khan
- Tebian Hassanein Ahmed Ali
- Tessa Fautz
- Tewodros Worku
- Thamer Nouh
- Thays Brunelli Pugliesi
- Thea Dimech
- Thelma Tembo
- Thelma Xerri
- Theodore Pezas
- Theodosios Theodosopoulos
- Thiago Fernandes Giuriato
- Thierry Alihonou
- Thomas Feidantsis
- Thomas Fozard
- Thomas G Weiser
- Thomas M Drake
- Thomas Olagboyega Olajide
- Thomas Pinkney
- Thomas Prudhomme
- Thomas Sherman
- Thomas Tetens Moe
- Thuraya Alzayat
- Thusitha Sampath Hettiarachchi
- Tien Seng Bryan Lee
- Timothy White
- Tina Gaarder
- Tobias Schuetz
- Todisoa Emmanuella Christina Tolotra
- Tolg Cecilia
- Tom Am Malik
- Tom Arthur
- Tom Falconer Hall
- Tomas Abaliksta
- Tomas Jankus
- Tomas Poškus
- Tommaso Bocchetti
- Tommaso Campagnaro
- Tommaso Fontana
- Tony Mak
- Toqa Khafagy
- Torhild Veen
- Trude Beate Wold
- Tsz-Yan Katie Chan
- Tuan Nur'Azmah Tuan Mat
- Tunde Sholadoye
- Twc Mak
- Tyler Rouse
- Tzu-Ling Chen
- Uday Muddebihal
- Ufuk Karabacak
- Ulf Gunnarsson
- Ulf Gustafsson
- Umar Muktar
- Umberto Tedeschi
- Umme Salma
- Usama Hantour
- Uthman Alamoudi
- Valdemaras Jotautas
- Valentine Parent
- Vanessa Dina Palomino Castillo
- Vanessa Msosa
- Vania Guglielmo
- Vania Silvestri
- Vasileios Despotidis
- Vasileios Kalles
- Vasiliki Soulou
- Vassilis Kalles
- Veereanna Shatkar
- Venerand Barendegere
- Veronica Grassi
- Veronica Lazzari
- Vicky Jennings
- Victor Dassah
- Victor Etwire
- Victor Kong
- Victor Manuel Quintero Riaza
- Victor Nwinee
- Victoria K Proctor
- Vijaid Upadhyaya
- Vijay Gadhvi
- Viktorija Ambrozeviciute
- Viktorija Nevieraite
- Ville Sallinen
- Vimalakanthan Thanusan
- Vincas Jonas Banaitis
- Virgilijus Beisa
- Viviana Sollazzo
- Vivien Graffieille
- Vizir Jean Paul Nsengimana
- Vladimir Khokha
- Vollmer Sebastian
- Vu Thanh Hien Le
- Vytautas Gaižauskas
- Vytautas Lipnickas
- Wahid Anwer
- Wai Cheong Soon
- Wai Him Lam
- Wairimu Ndegwa
- Waleed Thabet
- Walid Adham
- Walter Forno
- Walter Ruiz Panez
- Wan Nurul 'Ain Wan Mohd Nasir
- Wanigasekara Senanayake Mudiyanselage Kithsiri Janakantha Senanayake
- Ward Hamsho
- Wasim Dar
- Wedyan Alhazmi
- Wei Guo
- Weiguang Ho
- Weihei Dao
- Wendy Leslie Messa Aguilar
- Wennweoi Goh
- Wifanto Saditya Jeo
- Wilfredo Pino
- William Appeadu-Mensah
- William Beasley
- William Bonney
- William Hutch
- William J Lossius
- William Milligan
- Willy Alcca Ticona
- Wing Sum Li
- Witold Chachulski
- Xavier Delforge
- Xianelle Rodriguez
- Xinwei Low
- Xue Wei Chan
- Ya Theng Neo
- Yacoubou Imorou Souaibou
- Yahaya Ukwenya
- Yahya Salama
- Yaseen Rajjoub
- Yasmein Ibrahim
- Yasmin Abd-Elrasoul
- Yasmin Elfouly
- Yasmin Hegazy
- Yasmin Soliman
- Yasser Abd El Salam
- Yee Wen Tan
- Yehia Zakaria
- Yella Reddy
- Yi Koon Tan
- Yi Ting Mok
- Yih Jeng Cheong
- Yiing Yee Gan
- Yishan Der
- Yogendra Praveen Mogan
- Yomna Allam
- Yomna Hosny Asar
- Yong Yong Tew
- Yousef Abuowda
- Yousra El Shoura
- Ysabel Esthefany Alejos Bermúdez
- Yuk Hong Eric Cheung
- Yuksel Altinel
- Yung Kok Ng
- Yuri Macchitella
- Yves Aigrain
- Yücel Cengiz
- Zaher Mikwar
- Zahra Jaffry
- Zain Ali Khan
- Zainab Iftikhar
- Zaynab M Elsayed
- Zhongtao Zhang
- Zi Hao Sam
- Zigmantas Urniežius
- Zilvinas Dambrauskas
- Zineb Bentounsi
- Zygimantas Tverskis
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2022
- Field of study
Background There is a substantial gap in provision of adequate surgical care in many low- and middle-income countries. This study aimed to identify the economic burden of unmet surgical need for the common condition of appendicitis. Methods Data on the incidence of appendicitis from 170 countries and two different approaches were used to estimate numbers of patients who do not receive surgery: as a fixed proportion of the total unmet surgical need per country (approach 1); and based on country income status (approach 2). Indirect costs with current levels of access and local quality, and those if quality were at the standards of high-income countries, were estimated. A human capital approach was applied, focusing on the economic burden resulting from premature death and absenteeism. Results Excess mortality was 4185 per 100 000 cases of appendicitis using approach 1 and 3448 per 100 000 using approach 2. The economic burden of continuing current levels of access and local quality was US 92492millionusingapproach1and73 141 million using approach 2. The economic burden of not providing surgical care to the standards of high-income countries was 95004millionusingapproach1and75 666 million using approach 2. The largest share of these costs resulted from premature death (97.7 per cent) and lack of access (97.0 per cent) in contrast to lack of quality. Conclusion For a comparatively non-complex emergency condition such as appendicitis, increasing access to care should be prioritized. Although improving quality of care should not be neglected, increasing provision of care at current standards could reduce societal costs substantially
Global economic burden of unmet surgical need for appendicitis
- Author
- Aahlin Eirik Kjus
- Aamer Ahmed
- Aaniana Kenneth
- Ababneh Ali
- Abaliksta Tomas
- Abantanga Francis
- Abbas Mohamed
- Abbasy Jibran
- Abbo Olivier
- Abbouch Meryem
- Abd-Elmawla Manar
- Abd-Elrasoul Yasmin
- Abdallah Emad
- Abdel-Aty Abdulrahman
- Abdel-Hameed Noran
- Abdel-Kader Sara Mahmoud
- Abdel-Wahab Nehal Yosri Elsayed
- Abdelaal Abdelaziz
- Abdelaty Mohamed
- Abdelazeam Anan Rady
- Abdelazim Galaleldin
- Abdelaziz Mohamed A
- Abdelbadeai Kholoud
- Abdelfatah Afnan
- AbdelFattah Ibrahim
- Abdelgelil Asmaa
- Abdelghany Sarah
- Abdelhady Samar
- Abdelhamed Rasha
- Abdelhamid Amina
- Abdelhaq Aram
- Abdelkader Mostafa
- Abdelkader Omar
- Abdelkareem Ahmed
- Abdelkhalek Mohamed
- Abdelmageed Eman
- Abdelmotaleb Ibrahem
- Abdelraheim Mohamed
- Abdelraouf Ahmed Mahmoud
- Abdelrouf Doaa Maher
- Abdelshafy Mahmoud
- Abdelshakour Mahmoud
- Abdrabou Abdulshafi Khaled
- Abdul-Latif Saiba
- Abdulaziz Hager
- Abdulbagi Omar
- Abdulgawad Mahmoud
- Abdulhakeem Eman Mahmoud
- Abdullah Mohamed Abozed
- Abdullah Nik Azim Nik
- Abdullah Noha
- Abdullahi Lawal
- Abdurrazzaaq Abdussemiu
- Abebe Nebiyou Seyoum
- Abebe Nebyou Seyoum
- Abem Owusu Emmanuel
- Abiola Olajide
- Aboarab Aya
- Aboelella Majed
- Aboelmagd Omnia
- Aboelsoud Moustafa R.
- Aboraya Metwally
- Aboraya Mohammad
- Abouelnasr Alaa
- Aboul-Naga Mariam Saad
- Abouzahra Amany
- Abouzaid Arwa
- Abozaid Mohamed
- Abozeid Khaled
- Abozyed Mahmoud Ahmed Fathi
- Abu-toyour Maram
- Abubakr Marwan
- Abudeeb Haytham
- Abuowda Yousef
- Abuqwaider Eman
- Abusalem Lana
- Abuseif Mohamed
- Abushamleh Soha
- Ackom Eric
- Acquah Emmanuel
- Adam Nourhan
- Adams Ryan
- Adamu Ahmed
- Adawi Ihdaa
- Adawi Mohammad
- Adebanjo Ademola
- Adebola Oluwaseyi
- Adedeji Adesina
- Adekoya Adeleke
- Adel Abdalrahman
- Adel Ahmed
- Adel Badr Eldin
- Adel Israa
- Adella Fidelis Jacklyn
- Adelshone Abdelrahman
- Ademuyiwa Adesoji O
- Adenekan Babajide
- Adeniran James
- Adeniyi Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adesuyi Abidemi
- Adeyeye Ademola
- Adham Walid
- Adhitama Novia
- Adil Muhammad
- Adisa Adewale O
- Adnan Ahmad Bin
- Adu-Aryee Niiarmah
- Afana Samah
- Afandy Ahmed
- Afifi Ahmed Mohamed
- Africa South
- Agalianos Christos
- Agarwal Arnav
- Agbedinu Kwabena
- Agius Marija
- Aglan Amro
- Aguilar Wendy Leslie Messa
- Aguilar-Jimenez Jose
- Aguilera Maria Lorena
- Aguilera Omar
- Aguilera-Arevalo Maria-Lorena
- Ahlonsou Germain
- Ahlqvist Sandra
- Ahmed Ahmed
- Ahmed Asdaq
- Ahmed Ataa
- Ahmed Emad Ali
- Ahmed Hala
- Ahmed Hayam
- Ahmed Hussien
- Ahmed Lopna Ahmed Mohamed
- Ahmed Sara
- Ahmed Saraibrahim
- Ahmed Soliman Magdy
- Ahounou Ernest Yemalin Stephane
- Aigrain Yves
- Ajah Jonathan
- Ajai Olalekan
- Ajao Akinlabi E
- Ajiboye Anthony
- Akatibo Emmanuel
- Akeel Nouf
- Akoto Elliot
- Al-Aarag Asmaa Abdel-Rahman
- Al-Azraqi Israa Abdullah Aziz
- Al-Buhaisi Alaa
- Al-Dakka Emad
- Al-Faifi Jubran J
- Al-faqawi Maha
- Al-farram Hadeel
- Al-Hameedi Hasan Ismael Ibraheem
- Al-Hasani Ruqaya Kadhim Mohammed Jawad
- Al-khatib Ahmed
- Al-Mallah Abdullah
- Al-Marakby Dina
- Al-Mousa Mashael
- Al-Nahrawi Safwat
- Al-Obaedi Ossama
- Al-saqqa Sara
- Al-Saqqa Sara W
- Al-shammari Abeer
- Al-Slaibi Ibrahim
- Al-taher Taher
- Alada Muslimat
- Alahmady Omar
- Alakaloko Felix
- Alaloul Enas
- Alamin Shadid
- Alamoudi Mohammed
- Alamoudi Uthman
- Albeladi Bandar
- Albiety Adel
- Aldalaq Ahmad
- Aldhafeeri Salman
- Aledrisy Mohannad
- Alexander Philip
- Alexandre Challine
- Alfarsi Muayad Ahmed
- Alghamdi Ahmed
- Alghamdi Basim
- Alghamdi Masood
- Alghamdi Mohammed Saleh A.
- Algohary Osama
- Alhabli Ibrahim
- Alhady Khaled
- Alhassan Basmah
- Alhazmi Wedyan
- Alhendy Mohammed
- Alherz Mohammad
- Ali Ahmad
- Ali Ahmed
- Ali Ased
- Ali Citra Dewi Mohd
- Ali Elsayed
- Ali Farah Mahmoud
- Ali Hussein
- Ali Safia
- Ali Samuel Sani
- Ali Syed Abdul Wahhab Eusoffee Wan
- Ali Tebian Hassanein Ahmed
- Alihonou Thierry
- Alimi Quentin
- Aliyu Halima
- Aliyu Mohammad
- Aliyu Shamsudeen
- Aljboor Khaled
- Aljiffry Murad
- Aljohani Emad
- Aljohani Saud
- Alkaaki Aroub
- Alkammash Abdelrahman
- Alkelani Muhammad
- Alkhabbaz Dalia
- Allam Meran
- Allam Mostafa
- Allam Yomna
- Allegri Andrea
- Allen John Lee Y
- Almallah Ahmad
- Almanon Christel Leanne
- Almoflihi Abdullah
- Almuallem Sultan
- Almy Jack
- Alnaby Mohamed Hassab
- Alnawam Ehab
- Alnuqaydan Saleh A.
- Alnusairat Aseel
- Alomar Ibrahim N.
- Alqahtani Enas
- Alqahtani Saleh
- Alrahawy Mahmoud
- Alrajraji Mawaddah
- Alrifaie Ahmad
- AlRowais Mohammed
- Alsaggaf Mohammed
- Alsaggaf Mohammed Ubaid
- Alser Osaid H.
- Alshareef Reham
- Altaf Abdulmalik
- Altamimi Abdullah
- Altamimi Afnan
- Altamini Afnan
- Altarayra Marwa
- Althwainy Amani
- Altibi Ahmed
- Altinel Yuksel
- Altoe Fernanda
- Altwigry Abdulrahman M.
- Altwijri Abdulaziz
- Alvarez Ismael Isaac Zelada
- Alvi Abdul Rehman
- Alwafai Mohammad Ghassan
- Aly Abouelatta Khairy
- Aly Mohammed Yahia Mohamed
- Alyacoubi Said
- Alyahya Reem
- Alyami Rifan
- AlYoussef Ibrahim
- Alzahrani Ahmed
- Alzahrani Mohammed
- Alzayat Thuraya
- Aman Nowrin F.
- Amandito Radhian
- Ambrozeviciute Viktorija
- Ameen Mohamed
- Amer Mohamed A
- Amin Hager Abdul Aziz
- Amin Jasim
- Amin Shadid Al
- Amjad Mohammadasim
- Ammar Mohamed
- Ammar Mohamed Sabry
- Amoah Michael
- Amoako Joachim
- Amoako Philip Taah
- Amoako-Boateng Mabel
- Amole Isaac
- Amreia Mahmoud
- Anderson-Knight Hannah
- Andersson Linda
- Andika Ferry Fitriya Ayu
- Andreotti Dario
- Angelieri Daniele
- Anis Echaieb
- Ansaloni Luca
- Antar Sarah
- Antezana Diego
- Anthoulakis Christos
- Antoniozzi Angelo
- Anwar Abdul Wahid
- Anwar Nourhan
- Anwer Wahid
- Anyanwu Lofty-John
- Aonzo Paolo
- Appeadu-Mensah William
- Appiah Eric Kofi
- Aql Shaimaa
- Aquilino Fabrizio
- Arachchi Prasad Pitigala
- Arachchige Lalith Asanka Jayasooriya Jayasooriya
- Arafa Omar
- Arafa Sara
- Arango Maria Clara Mendoza
- Araujo Rafael
- Arcudi Claudio
- Ardley Rohan
- Arenas Andy
- Aristizã¡bal Fred Alexander Naranjo
- Arman Sam
- Armellini Andrea
- Arnaud Alexis Pierre
- Arshad Mohammad Mohsin
- Arsyad Hasbi Maulana
- Arthur Tom
- Arulampalam Tan
- Aruldas Neerav
- Asal Mohamed
- Asar Yomna Hosny
- Asare-Bediako Kwasi
- Asele Frehun Ayele
- Ashal Gehad El
- Ashour Ahmad
- Ashour Khlood
- Ashtari Morvarid
- Ashton Annelisse
- Asi Fatema
- Asilah Siti Mohd Desa
- Assal Abdelrahman
- Assouto Pamphile A
- Asturias Sabrina
- Asumah Hamza
- Ata Ahmed
- Ata Ali Amin Ahmed
- Ata Aya Yehia
- Atiyeh Anwar
- Atkins Ebenezer Takyi
- Atkinson Kieran
- Atobatele Kazeem
- Attallah Noura A.
- Attar Samaa Mahmoud Al
- Attard Myranda
- Attia Attia
- Attia Attia Mohamed
- Augestad Knut Magne
- Aung Kyaw Phyo
- Austraite Aiste
- Aviles Susan
- Avoka Anthony
- Awad Israa
- Awad Sawsan Adel
- Awuku-Asabre Joseph
- Awwad Saad Al
- Ayad Sara
- Ayandipo Omobolaji O
- Ayyar Shruti
- Aziz Dayang Nita Abdul
- Aziz Mohamed Rezal Abdul
- Aziz Nora Abdul
- Azizeldine Mohammed G.
- Azmitia José René Arévalo
- Azzie Georges
- Azzis Olivier
- Baba Suleiman
- Bachri Houda
- Badawy Mahmoud
- Badenjki Mohamed Adel
- Badr Ahmed
- Badr Mohamed Fawzy Mahrous
- Badwi Nermin M
- Badwi Nermin Mohamed
- Badwy Assmaa
- Bahar Suraya
- Baheeg Mohamad
- Bailey Karen
- Baird Alan
- Bakhaidar Mohamad
- Bakr Ahmad
- Bakry Hesham Mohammed
- Bala Miklosh
- Balalis Dimitrios
- Baldacchino Matthew
- Balducci Genoveffa
- Balila Reem Mohammed Hassan
- Balkan Ali Zeynel Abidin
- Ball Alasdair
- Ballouhey Quentin
- Balmaceda Rubén
- Balogun Fatai
- Baltrunas Robertas
- Baluch Fatima
- Bamicha Anastasia
- Bamicha Athanasia
- Banaitis Vincas Jonas
- Bandoh Dickson
- Bani-Sadar Ahmad
- Banipal Gurpreet Singh
- Baraka Heba
- Barakat Sara Abd Elmageed
- Barendegere Venerand
- Barkolias Christos
- Barnabas Gandau Naa
- Barneo Luis
- Barrantes Ana Maria Sandoval
- Barrawi Fayez Elian Al
- Barreda Luis Miguel Alvarez
- Barrientos Linda Alvi Madrid
- Barrios Emanuel
- Barrios Emmanuel
- Basilicò Silvia
- Basir Elissa Rifhan Mohd
- Bassem Monica
- Bassit Khalil Abdul
- Basso Celeste Del
- Basso Stefano M. M
- Bastawis Fatema Al
- Basto Carlos Alejandro Arroyo
- Bautista Ana Cecilia Manchego
- Beasley William
- Bedada Alemayehu Ginbo
- Bediako-Bowan Antoinette
- Behar Nebil
- Beisa Virgilijus
- Bekhet Amira Hassan
- Bekhet Nada Mohamed
- Beleño Alvaro Enrique Mendoza
- Belkouchi Abdelkader
- Belli Andrea
- Bello Bashir
- Benammi Sarah
- Benevento Angelo
- Bennai Redouane Mammar
- Bentounsi Zineb
- Benyaiche Chaymae
- Bermúdez Ysabel Esthefany Alejos
- Berti Stefano
- Bertuello Isaac
- Beuran Mircea
- Bezzina Maureen
- Bhangu Aneel
- Bhat Sriram
- Bhatnagar Ankur
- Bhopal Kamran Faisal
- Bianco Federica
- Bigaran Annamaria
- Billy Matthew
- Birindelli Arianna
- Birring Amerdip
- Björklund Ida
- Blanco Ruth
- Blencowe Natalie
- Bliksøen Marte
- Blower Emma
- Boakye-Yiadom Kwaku
- Bocchetti Tommaso
- Bode Chris
- Bode Christopher
- Boijsen Magnus
- Bonavia Karl
- Bonavina Luigi
- Bondin John
- Bondurri Andrea
- Boni Davide De
- Boni Silvia
- Bonnard Arnaud
- Bonney William
- Bono Phoebe De
- Borda-Luque Giuliano
- Borg Elaine
- Borin Eva
- Bortolasi Luca
- Botero Jaime Andres Montoya
- Botes Stefan
- Bottini Corrado
- Botto Nathalie
- Bouali Ourdia
- Bougard Heather
- Boukhal Khaoula
- Bowabsak Alaa
- Bowe Ross
- Bowley Doug
- Bradulskis Saulius
- Bratu Matei
- Bratu Matei Razvan
- Bratu Razvan-Matei
- Braungart Sarah
- Bravo Jorge Armando Chungui
- Bray Lemuel Davies
- Breitenstein Stefan
- Bréaud Jean
- Brincat Svetlana Doris
- Brocca Antonella La
- Broch Aline
- Brown Damien
- Brown James
- Brown Jason
- Brunoni Beatrice
- Bsisu Isam
- Bucci Luigi
- Bugeja Roberta
- Buisson Philippe
- Bukari Mohammed
- Burger Sule
- Burmistrovas Andrius
- Burns Hannah
- Bustangi Nasir
- Butt Muhammad Talha
- Cabrera Carla Cecilia Ramãrez
- Cacurri Alban
- Cadogan Diana Duarte
- Cahill Ronan
- Callan Rory
- Calua Alexander Canta
- Camacho Rony
- Cameron Brian
- Camilleri Georgette Marie
- Camilleri-Brennan John F.
- Camilleri-Brennan Julian
- Campagnaro Tommaso
- Canto Massimiliano Dal
- Capito Carmen
- Carabott Kurt
- Cardozo Jorge Torres
- Cardozo Ramón Augusto Melo
- Careta Maíra Cassa
- Carlucci Michele
- Carmona Juan Manuel
- Carpio Juan
- Carrasco Nahilia
- Carreira Jo-Anne
- Cassar Kristina
- Castillo Vanessa Dina Palomino
- Castro Manuel Rodriguez
- Catani Marco
- Cautiero Roberto
- Cecilia Tolg
- Celis Jose María Vergara
- Cengiz Yücel
- Ceriani Chiara
- Chachulski Witold
- Chai Chu-Ann
- Chai Feng Yih
- Chan Tsz-Yan Katie
- Chan Xue Wei
- Chang Kate Yu-Ching
- Chapman Stephen J
- Charles Angeline
- Cheah Alvin Ee Zhiun
- Chen Tzu-Ling
- Chenn Roxanne
- Cheong Yih Jeng
- Chetta Nicola
- Cheung Yuk Hong Eric
- Chew Luen Shaun
- Chibuye Chali
- Chiesa Deborah
- Chin Pui Xin
- Chiong Jose Antonio Cabala
- Chiu Selina
- Chiu Selina Man Yeng
- Choi Philip
- Chong Bryon Frankie Hon Khi
- Chong Chean Leung
- Chong Choon Seng
- Chong Hoong-Yin
- Chow Crystal Yern Nee
- Chu Kathryn
- Chung Kuet Jun
- Chung Siyi
- Ciccioli Eleonora
- Cirocchi Roberto
- Ciubotaru Cezar
- Claire Raquillet
- Clarissa Audrey
- Clegg-Lamptey Joe-Nat
- Clement Keiran David
- Clements Joshua Michael
- Clerico Giuseppe
- Clifford Caroline
- Cloro Luigi Maria
- Coccolini Federico
- Cocker DM
- Cocorullo Gianfranco
- Cohen David Monterroso
- Coletta Diego
- Coletti Massimo
- Colombani Jean-Francois
- Cona Camilla
- Conci Simone
- Confalonieri Gianmaria
- Conlon Kevin C.
- Connor Katie
- Conte Annalisa lo
- Contreras-Vergara Ana Lucia
- Coomber Ross
- Coompson Christian Lari
- Corbellini Carlo
- Corbellino Mario
- Cornick Jen
- Coronel Jazmin
- Correa Juan Camilo
- Costa Cecilia
- Costa-Maia Jose
- Costas-Chavarri Ainhoa
- Courboin Etienne
- Cox Daniel
- Cox Michael
- Coyoy-Gaitan Otto
- Cross Kate
- Cruz Danilo Herrera
- Cruz Herman
- Cucumazzo Stefano
- Curletti Gianluca
- Currow Chelise
- Cury Alyne Daltri Lazzarini
- D'aguzan Nicole
- D'amours Scott K
- D'cruz Reuban
- Dabboor Majd
- Dabbour Kareem
- Dabessa Daniel
- Dablouk Mohamed
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- Elsayed Zaynab M
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- Farinella Eriberto
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- Fermani Claudio
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- Fowler Alexander J
- Fozard Thomas
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- Hall Tom Falconer
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- Har Prisca A. L.
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- Haroun Abdelrahman
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- Hassanein Adel B
- Havemann Ingemar
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- Kamil Rahma
- Kanani Arezo
- Kandil Ahmedali M
- Kandil Hend
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- Kinnera S. V.
- Kirby Andrew
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- Kiudelis Mindaugas
- Kjellin Ann
- Klappenbach Roberto
- Knight Stephen R
- Koay Kean Leong
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- Lossius William J.
- Low Xinwei
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- Major Piotr
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- Mamdouh Ehab
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- Mihaljevic Andre L
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- Moghazy Mahmoud Elsayed
- Mohamed Ahmed Rabie
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- Mohamed Amna Mamdouh
- Mohamed Arwa
- Mohamed Bakeer
- Mohamed Fawzy
- Mohamed Mazed
- Mohamed Mohamed Abdelaty
- Mohamed Mohamed Awad Elkarim Hamad
- Mohamed Mohamed Moamen
- Mohamed Osama
- Mohamed Shaza Rabie
- Mohameden Ahmed
- Mohammad Aminu
- Mohammed Abdelrahman
- Mohammed Ahmed
- Mohammed Ahmed Rabeih
- Mohammed Amany Eldosouky
- Mohammed Hussein
- Mohammed Mohammed Mustafa
- Mohammed Mohammed Mustafa Hassan
- Mohammed Sara
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- Mohan Midhun
- Mok Yi Ting
- Mokhtar Ahmed
- Mollo Melanie Castro
- Monahan Mark
- Monrad-Hansen Peter Wiel
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- Moore Rachel
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- Morsi Ashraf
- Morsi Mahmoud
- Morton Dion
- Morton Dion G
- Morton Robert
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- Mosalum Omnia
- Mostafa Hassan Ali
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- Mustafa Mennat-Allah
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- Mustafa Mousa
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- Thanusan Vimalakanthan
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- Thompson Ben
- Thorarinsdottir Hildur
- Thorell Anders
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- Valioulis Ioannis
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- Vega Gustavo Miguel Machain
- Velasquez Ricardo
- Velásquez Armando José Román
- Velásquez Carlos Iván Pérez
- Vella-Baldacchino Martinique
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- Vendramin Elena
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- Walsh Michael
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- Weber Beatrix
- Weber Per
- Weiser Thomas G
- Wheeler James
- Whitaker John
- White Timothy
- Whitehurst Katharine
- Wiborg Joachim
- Widiastini T Ariani
- Wild Jonathan R L
- Williams Omolara
- Wilson Ling
- Wilson Michael
- Witherspoon Paul
- Wogensen Fredrik
- Woin Evelina
- Wold Trude Beate
- Wolf Bernhard
- Wondimu Sahlu
- Wondoh Paul
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- Wong Chui Yee
- Wong Hong Yee
- Wood Greta
- Woodward Helen
- Worku Mengistu
- Worku Tewodros
- Wredberg Cecilia
- Wright Naomi J
- Xerri Thelma
- Yahaya Muhammad Taqiyuddin
- Yakubu Musah
- Yam Sir Young
- Yang James
- Yaseen Tahir
- Yaseen Tahir Muhammad
- Yavuz Mehmet Ali
- Ye Joselyn
- Yeang Li Jing
- Yeo Lee Shi
- Yeung Man Hon Andrew
- Yifieyeh Abiboye
- Yip Chingwan
- Yip Sebastian Bernardo Shu
- Ymeri Shpetim
- Yoganathan Pigeneswaren
- Yong Cheryl Ou
- Yong Guo Liang
- Youssef Daniel
- Youssef Haney
- Youssef Mohamed
- Youssif Jehad Hassan
- Yuksek Mahmut Arif
- Yusufali Taha
- Zaa'treh Rula
- Zachariades Dimitris-Christos
- Zadoroznas Antanas
- Zahran Diaaaldin
- Zakaria Esraay
- Zakaria Mahmoud
- Zakaria Yehia
- Zaki Ahmed
- Zalabia Mohamed F
- Zamarin Kresimir
- Zammit Stefan
- Zampitis Nikolaos
- Zani Augusto
- Zanini Nicola
- Zapata Felipe
- Zarb Ciskje
- Zardab Ali
- Zegarra Sergio
- Zerihun Abebe Bekele
- Zhang Zhongtao
- Zheng Fei
- Zidan Hagar
- Zidan Mohamed
- Ziff Oliver
- Zil-E-Ali Ahsan
- Zohair Ahmed
- Zuber Markus
- Zulkifli Athirah
- Žilinskas Justas
- Žilinskienė Reda
- Žiubrytė Greta
- Publication venue
- Publication date
- 01/01/2022
- Field of study
Background There is a substantial gap in provision of adequate surgical care in many low- and middle-income countries. This study aimed to identify the economic burden of unmet surgical need for the common condition of appendicitis. Methods Data on the incidence of appendicitis from 170 countries and two different approaches were used to estimate numbers of patients who do not receive surgery: as a fixed proportion of the total unmet surgical need per country (approach 1); and based on country income status (approach 2). Indirect costs with current levels of access and local quality, and those if quality were at the standards of high-income countries, were estimated. A human capital approach was applied, focusing on the economic burden resulting from premature death and absenteeism. Results Excess mortality was 4185 per 100 000 cases of appendicitis using approach 1 and 3448 per 100 000 using approach 2. The economic burden of continuing current levels of access and local quality was US 92492millionusingapproach1and73 141 million using approach 2. The economic burden of not providing surgical care to the standards of high-income countries was 95004millionusingapproach1and75 666 million using approach 2. The largest share of these costs resulted from premature death (97.7 per cent) and lack of access (97.0 per cent) in contrast to lack of quality. Conclusion For a comparatively non-complex emergency condition such as appendicitis, increasing access to care should be prioritized. Although improving quality of care should not be neglected, increasing provision of care at current standards could reduce societal costs substantially
SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study
- Author
- Aamir Junaid
- Abaalkhail Muath
- Ababneh Adnan
- Ababneh Hazim
- Ababneh Laila
- Ababneh Roba
- Abad-Motos Ane
- Abaker Mussab
- Abary Ryan
- Abass Adam
- Abate Emmanuele
- Abayomi Olukayode
- Abazeed Alaa
- Abbad Bader
- Abbadessa Francesco
- Abbadi Osaid
- Abbakar Malaz
- Abbas Ahmed
- Abbas Alzhraa
- Abbas Asad
- Abbas Aya
- Abbas Jihad
- Abbas Manzar
- Abbas Mohammad
- Abbas Omer
- Abbasov Aykhan
- Abbo Olivier
- Abbott Daniel
- Abbott Tom
- Abboud Omar
- Abd Waleed
- Abd-Elkariem Ahmed
- Abd-Elsalam Sherief
- Abdalah Ahmad
- Abdalhadi Alya
- Abdalla Ahmed
- Abdalla Eman
- Abdalla Samir
- Abdalla Shimaa
- Abdalla Siddig
- Abdallah Emne
- Abdallah Ghaida
- Abdallah Lubna
- Abdallah Munir
- Abdallah Murad Al
- Abdallah Rasha
- Abdalnour Hani
- Abdeen Bashar
- Abdeewi Saedah
- Abdeh Louai
- Abdel-Aleem Mahmoud
- Abdel-Elsalam Wafaa
- Abdel-Fattah Areej
- Abdel-Fattah Nour
- Abdel-Hafez Ibrahim
- Abdelaal Abdelrahman
- Abdelaty Ahmed Adel
- Abdelazeem Khaled
- Abdelaziz Areej
- Abdelaziz Mohammed
- Abdelbagi Mohamad
- Abdelbaset Abouelnour
- Abdeldayem Hesham
- Abdelfattah Mahmoud
- Abdelgadir Alwaleed
- Abdelgalel Khaled
- Abdelghafar Moslem
- Abdelhafez Mohammed
- Abdeljalil Abdelkarim
- Abdelkabir Mohammed
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- De Silva Chathuranka
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- Jarmozi Buthina Al
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- Jayyab Mustafa Abu
- Juarranz Miguel Alonso
- Junior Joel
- Júnior Samuel Aguiar
- Kalbani Maha Al
- Kalbani Moza Al
- Kamarajah Sivesh
- Kharusi Lamya Al
- Kharusi Safiya Al
- Khassawneh Ahmad Al
- Koculen
- Köylü Zehra Alan
- Lahham Salim Al
- Lara Iván Andújar
- Lara María Adrien
- Li Elizabeth
- Lucas Miriam Abellan
- Maadany Faraj Al
- Mahdawi Leyla Al
- Mahdy Hossam Al
- Makari Reem Al
- Manji Adil Al-Karim
- Maqtari Siham Al
- Mariño Mauricio Agüero
- Martinez Yicel Alvarez
- Maryam A
- Matas Fernando Alcaide
- Mendoza Veronica Alonso
- Mensah Kwasi Agyen
- Mintah Dominic Annor
- Moagal Rehab Al
- Moawad Karim Abdelraouf
- Mohamed Mohamed Ali
- Mohsen Mustafa Abo
- Momani Tareg Al
- Muhfouz Dima Abu
- Muhtadi Fadhl Al
- Mulke Rahaf Al
- Murgueitio Natalia Cortes
- Mutani Mohammed Al
- Nafesa Aminah Al
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- Noval Patricia Corriols
- Nwijy Khaled Ai
- Obead Hamza Abu
- Oliver Renato Aguera
- Omair Shehanah Al
- Otaibi Faisal Al
- Picciochi Maria
- Pinto João Almeida
- Polo Miriam Abdulkarim
- Qadhi Hani Al
- Qudhaya Rashed Al
- Qureshi Talha Ahmed
- Rahim Norazila
- Rahman Noorneza Abdul
- Rahman Norhafiza
- Raisi Amani Al
- Rashed Asmaa Al
- Rego Juliana Almeida
- Riaz Shujat Ahmed
- Riobello Eva Andreu
- Riyami Nihal Al
- Riyami Salim Al
- Ros Conrado Andrés
- Roselló Irene Vives
- Rubio Eva Corral
- Rueda Ignacio Alcalá
- Saad Sarah Ahmed
- Sabti Hilal Al
- Saez Iago Alvarez
- Saied Ghiath Al
- Salam Omar Abdul
- Salama Ibrahim Abdelkader
- Sanany Ghadeer Al
- Santos Daniel Costa
- Sayed Mohamed Al
- Sebastian Isabel Alonso
- Shaalah Ahmed Abdullah
- Shaibi Maha Al
- Shaikh Shafqat Ali
- Shanab Ahmed Abo
- Sharie Ahmed Al
- Shukri Asmaa Al
- Simoes Joana
- Smadi Omar Al
- Soares Rui Costa
- Soucheiron Maria Coronas
- Subaie Saud Al
- Suyyagh Kais Al
- Tarieh Ammar Abu
- Torres Eva Alvarez
- Victoria Czarlo Dela
- Villamayor Verónica Alen
- Vinayagam Raman
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- Vincenzi Matteo
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- Virgilio Edoardo
- Virgincar Ashwini
- Virta Ville P
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- Vishnoi Jeewan Ram
- Vishwakarma Sunil Kumar
- Vishwani Vartika
- Vissapragada Ravi
- Viste Claire
- Viswanath Yks
- Vitowanu Julius
- Viveiros Octavio
- Viveros-Carreño David
- Vives Inmaculada
- Vives-Barquiel Marian
- Vivian-Taylor Josephine
- Vix Michel
- Vlad Ioan Catalin
- Vlad Schitcu
- Vladimir Novgorodskii
- Vleminckx Nils
- Vo Uyen Giao
- Vogel Jon
- Vogel Keianna
- Vogel Rachel
- Vogelsang Holger
- Vogler Thomas
- Vogt Kelly
- Vohra Ravinder
- Vokshi Ismail
- Volkova Olga
- Volpe Gustavo Jardim
- Volpin Enrico
- Volpin Francesco
- von Ehrlich-Treuenstätt Viktor H
- von Renesse Janusz
- von Rundstedt Friedrich-Carl
- Voonna Murali Krishna
- Voppuru Saiesh Reddy
- Vora Sameer
- Voros Peter
- Vosoughi Fardis
- Vossler Kristen
- Vounckx Manon
- Vourganti Srinivas
- Vovola Fernanda
- Vozian Marin
- Vrakopoulou Gavriella Zoi
- Vömel Jacob
- Wadei Hajr Al
- Yahya Zakaria Al
- Zahran Mohammed
- Zahrani Attiya Al
- Zahrani Turki Ai
- Zaid Muna
- Zein Zeina Al
- Álvarez Sofia
- Älgå Andreas
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2021
- Field of study
Background: Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling.
Methods: The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18-49, 50-69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty.
Results: NNVs were more favourable in surgical patients than the general population. The most favourable NNVs were in patients aged 70 years or more needing cancer surgery (351; best case 196, worst case 816) or non-cancer surgery (733; best case 407, worst case 1664). Both exceeded the NNV in the general population (1840; best case 1196, worst case 3066). NNVs for surgical patients remained favourable at a range of SARS-CoV-2 incidence rates in sensitivity analysis modelling. Globally, prioritizing preoperative vaccination of patients needing elective surgery ahead of the general population could prevent an additional 58 687 (best case 115 007, worst case 20 177) COVID-19-related deaths in 1 year.
Conclusion: As global roll out of SARS-CoV-2 vaccination proceeds, patients needing elective surgery should be prioritized ahead of the general population