746 research outputs found
The Extremes of Thermonuclear Supernovae
The majority of thermonuclear explosions in the Universe seem to proceed in a
rather standardised way, as explosions of carbon-oxygen (CO) white dwarfs in
binary systems, leading to 'normal' Type Ia supernovae (SNe Ia). However, over
the years a number of objects have been found which deviate from normal SNe Ia
in their observational properties, and which require different and not seldom
more extreme progenitor systems. While the 'traditional' classes of peculiar
SNe Ia - luminous '91T-like' and faint '91bg-like' objects - have been known
since the early 1990s, other classes of even more unusual transients have only
been established 20 years later, fostered by the advent of new wide-field SN
surveys such as the Palomar Transient Factory. These include the faint but
slowly declining '02es-like' SNe, 'Ca-rich' transients residing in the
luminosity gap between classical novae and supernovae, extremely short-lived,
fast-declining transients, and the very luminous so-called
'super-Chandrasekhar' SNe Ia. Not all of them are necessarily thermonuclear
explosions, but there are good arguments in favour of a thermonuclear origin
for most of them. The aim of this chapter is to provide an overview of the zoo
of potentially thermonuclear transients, reviewing their observational
characteristics and discussing possible explosion scenarios.Comment: Author version of a chapter for the 'Handbook of Supernovae', edited
by A. Alsabti and P. Murdin, Springer. 50 pages, 7 figure
Homogenization of Variational Inequalities for the p-Laplace Operator in Perforated Media Along Manifolds
We address homogenization problems of variational inequalities for the p-Laplace operator in a domain of Rn (n ? 3, p ? [2, n)) periodically perforated by balls of radius O(??) where ? > 1 and ? is the size of the period. The perforations are distributed along a (n ? 1)-dimensional manifold ? , and we impose constraints for solutions and their fluxes (associated with the p-Laplacian) on the boundary of the perforations. These constraints imply that the solution is positive and that the flux is bounded from above by a negative, nonlinear monotonic function of the solution multiplied by a parameter ? ?? , ? ? R and ? is a small parameter that we shall make to go to zero. We analyze different relations between the parameters p, n, ?, ? and ?, and obtain homogenized problems which are completely new in the literature even for the case p = 2.This work has been partially supported by the Spanish grant MINECO:MTM2013-44883-P
Cooperative coupling of ultracold atoms and surface plasmons
Cooperative coupling between optical emitters and light fields is one of the
outstanding goals in quantum technology. It is both fundamentally interesting
for the extraordinary radiation properties of the participating emitters and
has many potential applications in photonics. While this goal has been achieved
using high-finesse optical cavities, cavity-free approaches that are broadband
and easy to build have attracted much attention recently. Here we demonstrate
cooperative coupling of ultracold atoms with surface plasmons propagating on a
plane gold surface. While the atoms are moving towards the surface they are
excited by an external laser pulse. Excited surface plasmons are detected via
leakage radiation into the substrate of the gold layer. A maximum Purcell
factor of is reached at an optimum distance of
from the surface. The coupling leads to the observation of
a Fano-like resonance in the spectrum.Comment: 9 pages, 4 figure
Patient perspectives of a diagnosis of myeloproliferative neoplasm in a case control study
BACKGROUND: Myeloproliferative neoplasms (MPNs) including the classic entities; polycythemia vera (PV), essential thrombocythemia (ET) and primary myelofibrosis are rare diseases with unknown aetiology. The MOSAICC study, is an exploratory case-control study in which information was collected through telephone questionnaires and medical records. METHODS: As part of the study, 106 patients with MPN were asked about their perceived diagnosis and replies correlated with their haematologist's diagnosis. For the first time, a patient perspective on their MPN diagnosis and classification was obtained. Logistic regression analyses were utilised to evaluate the role of variables in whether or not a patient reported their diagnosis during interview with co-adjustment for these variables. Chi square tests were used to investigate the association between MPN subtype and patient reported categorisation of MPN. RESULTS: Overall, 77.4 % of patients reported a diagnosis of MPN. Of those, 39.6 % recognised MPN as a 'blood condition', 23.6 % recognised MPN as a 'cancer' and 13.2 % acknowledged MPN as an 'other medical condition'. There was minimal overlap between the categories. Patients with PV were more likely than those with ET to report their disease as a 'blood condition'. ET patients were significantly more likely than PV patients not to report their condition at all. Patients from a single centre were more likely to report their diagnosis as MPN while age, educational status, and WHO re-classification had no effect. CONCLUSIONS: The discrepancy between concepts of MPN in patients could result from differing patient interest in their condition, varying information conveyed by treating hematologists, concealment due to denial or financial concerns. Explanations for the differences in patient perception of the nature of their disease, requires further, larger scale investigation
Disruption of the serine/threonine protein kinase H affects phthiocerol dimycocerosates synthesis in Mycobacterium tuberculosis
Mycobacterium tuberculosis possesses a complex cell wall that is unique and essential for interaction of the pathogen with its human host. Emerging evidence suggests that the biosynthesis of complex cell-wall lipids is mediated by serine/threonine protein kinases (STPKs). Herein, we show, using in vivo radiolabelling, MS and immunostaining analyses, that targeted deletion of one of the STPKs, pknH, attenuates the production of phthiocerol dimycocerosates (PDIMs), a major M. tuberculosis virulence lipid. Comparative protein expression analysis revealed that proteins in the PDIM biosynthetic pathway are differentially expressed in a deleted pknH strain. Furthermore, we analysed the composition of the major lipoglycans, lipoarabinomannan (LAM) and lipomannan (LM), and found a twofold higher LAM/LM ratio in the mutant strain. Thus, we provide experimental evidence that PknH contributes to the production and synthesis of M. tuberculosis cell-wall components
Home advantage in the Winter Paralympic Games 1976–2014
Purpose: There is a limited amount of home advantage research concerned with winter sports. There is also a distinct lack of studies that investigate home advantage in the context of para-sport events. This paper addresses this gap in the knowledge by examining home advantage in the Winter Paralympic Games.
Methods: Using a standardised measure of success, we compared the performances of host nations at home with their own performances away from home between 1976 and 2014. Both country level and individual sport level analysis is conducted for this time period. Comparisons are also drawn with the Winter Olympic Games since 1992, the point from which both the Winter Olympic Games and the Winter Paralympic Games have been hosted by the same nations and in the same years.
Results:
Clear evidence of a home advantage effect in the Winter Paralympic Games was found at country level. When examining individual sports, only alpine skiing and cross country skiing returned a significant home advantage effect. When comparing home advantage in the Winter Paralympic Games with the Winter Olympic Games for the last seven host nations (1992–2014), we found that home advantage was generally more pronounced (although not a statistically significant difference) in the case of the former.
Conclusion: The causes of home advantage in the Winter Paralympic Games are unclear and should be investigated further
The Evolution of Compact Binary Star Systems
We review the formation and evolution of compact binary stars consisting of
white dwarfs (WDs), neutron stars (NSs), and black holes (BHs). Binary NSs and
BHs are thought to be the primary astrophysical sources of gravitational waves
(GWs) within the frequency band of ground-based detectors, while compact
binaries of WDs are important sources of GWs at lower frequencies to be covered
by space interferometers (LISA). Major uncertainties in the current
understanding of properties of NSs and BHs most relevant to the GW studies are
discussed, including the treatment of the natal kicks which compact stellar
remnants acquire during the core collapse of massive stars and the common
envelope phase of binary evolution. We discuss the coalescence rates of binary
NSs and BHs and prospects for their detections, the formation and evolution of
binary WDs and their observational manifestations. Special attention is given
to AM CVn-stars -- compact binaries in which the Roche lobe is filled by
another WD or a low-mass partially degenerate helium-star, as these stars are
thought to be the best LISA verification binary GW sources.Comment: 105 pages, 18 figure
Tuning the conductance of single-walled carbon nanotubes by ion irradiation in the Anderson localization regime
Carbon nanotubes are a good realization of one-dimensional crystals where
basic science and potential nanodevice applications merge. Defects are known to
modify the electrical resistance of carbon nanotubes. They can be present in
as-grown carbon nanotubes, but controlling externally their density opens a
path towards the tuning of the nanotube electronic characteristics. In this
work consecutive Ar+ irradiation doses are applied to single-walled nanotubes
(SWNTs) producing a uniform density of defects. After each dose, the room
temperature resistance versus SWNT-length [R(L)] along the nanotube is
measured. Our data show an exponential dependence of R(L) indicating that the
system is within the strong Anderson localization regime. Theoretical
simulations demonstrate that mainly di-vacancies contribute to the resistance
increase induced by irradiation and that just a 0.03% of di-vacancies produces
an increase of three orders of magnitude in the resistance of a 400 nm SWNT
length.Comment: 16 pages, 4 figure
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