8 research outputs found

    Intracerebral arteriovenous malformation: Diagnosis of a case with computerized tomography imaging

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    Cerebral arteriovenous malformations (AVM) are rarely diagnosed and reported from our region of the world possibly due to the paucity (even unavailability) of the necessary imaging modalities especially digital subtraction angiography (DSA). In this report we present the CT features making for the confident diagnosis of a case of cerebral AVM, even in the absence of a DSA. A 26-year-old man presented recently to us with history of headache not associated with any other general clinical or neurological deficits. An initial cranial contrast CT showed a right parietal 5 x 5cm parenchymal mass lesion with features highly suggestive of an AVM. The follow-up CT angiography later confirmed this lesion to be indeed a high grade AVM involving a high flow fistulous communication between the main branches of the right middle cerebral artery and the deep cerebral venous system. Where there is no facility for DSA like in our own practice there are some specific CT scan imaging features that afford fairly accurate diagnosis of cerebral AVMs

    Secondary fibrosarcoma of the brain stem treated with cyclophosphamide and Imatinib

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    Radiation-induced midbrain fibrosarcoma is a rare, highly aggressive tumor, which is associated with poor prognosis. We present the case of a 48-year old man with brainstem fibrosarcoma 20 years following radiation therapy received for a pituitary tumor. We discuss this case in the context of the diagnostic criteria for these tumors, and previous reports of secondary and primary sarcomas of the central nervous system

    A first update on mapping the human genetic architecture of COVID-19

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    A first update on mapping the human genetic architecture of COVID-19

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