485 research outputs found

    EATING HABIT AND NUTRITIONAL STATUS OF A NIGERIAN PRIVATE UNIVERSITY STUDENTS

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    The study aimed at determining the eating habit and nutritional status of Babcock university undergraduate students. Multiple stage random technique and systematic sampling was used to select 288 respondents and a structured questionnaire was used to elicit information on the socio-demographic data and eating habit. The BMI of the respondents was determined using weight and height squared and the 24- hour dietary recall was analyzed using Total Dietary Assessment software. The relationship between eating habit and nutritional status was determined using Chi- square.  Most of the respondents in the study were between 18-21 years (73.6 %) consisting of 45.6 % male and 53.7 % female. The respondents (54.8 %) consumed two meals in a day, 63.9 % eats in response to hunger while others eat due to different factors. Consumption of fruits and vegetables was poor as only 17.0 % and 14.9 % consumed fruits and vegetable daily. Many of the respondents consume snack regularly (85.4 %) with 33.7 % consuming in- between meals and 14.2 % snacking late in the night. Prevalence of overweight and obesity was high among the respondents as 30.4 % were overweight and 27.1 % were obese. Mean calorie intake and % RDA being 3223.04± 687.66 and 111.14 for males and 2429.45 ± 243.14 and 110.43 for females.   Frequency of consumption, snacking, period of snacking, soft drink consumption and, poor fruit and vegetable consumption all had significant (P< 0.05) effect on the nutritional status.                               &nbsp

    Comparison of Some Land Suitability Evaluating Methods for a Selected Gypsiferous Part in the Northern Karma Region for Irrigated Agriculture

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    To compare the efficiency of three systems to evaluate the suitability of Gypsiferous land for irrigated agriculture, an area of 8885.4 hectares was selected in the Tharthar region – Iraq within the Euphrates terrace, which formed at Pleistocene period and mainly consisted of gypsum, the study included a semi-detailed survey of the area's soil using the Free-lance method, by selecting three parallel transects, according to the variations in texture class, soil salinity and content of gypsum, five representative pedons locations were identified and morphologically described, also soil samples from each horizon were obtained, as well as we obtained water samples from the Euphrates river-Tharthar canal and every wells located in the study area, it's transferred to the laboratory and the required analyzes were performed. The result showed the predominance of the medium soil texture class and slightly saline soil class (S1) in the study area, with a decrease in the soil carbonate content, on the contrary the soil gypsum content was increased. All wall waters was salinity, which poses a danger to agricultural use, compared to the water of the Euphrates river. A discrepancy was observed between the obtained land suitability classes. While the Sys and Verheye, 1972 system showed two poor suitability classes, Sys et al. 1991 and Al-Baji et al. 2010 has improved the appropriateness of the varieties, but the Kadhim, 2012 system was the best in terms of application in order to include the quality of irrigation water within the classification, so its results were more close to the reality diagnosed during the field visits to the study area and the questionnaire from the land users of the regio

    Global burden of human brucellosis : a systematic review of disease frequency

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    BACKGROUND: This report presents a systematic review of scientific literature published between 1990-2010 relating to the frequency of human brucellosis, commissioned by WHO. The objectives were to identify high quality disease incidence data to complement existing knowledge of the global disease burden and, ultimately, to contribute towards the calculation of a Disability-Adjusted Life Years (DALY) estimate for brucellosis.METHODS/PRINCIPAL FINDINGS: Thirty three databases were searched, identifying 2,385 articles relating to human brucellosis. Based on strict screening criteria, 60 studies were selected for quality assessment, of which only 29 were of sufficient quality for data analysis. Data were only available from 15 countries in the regions of Northern Africa and Middle East, Western Europe, Central and South America, Sub-Saharan Africa, and Central Asia. Half of the studies presented incidence data, six of which were longitudinal prospective studies, and half presented seroprevalence data which were converted to incidence rates. Brucellosis incidence varied widely between, and within, countries. Although study biases cannot be ruled out, demographic, occupational, and socioeconomic factors likely play a role. Aggregated data at national or regional levels do not capture these complexities of disease dynamics and, consequently, at-risk populations or areas may be overlooked. In many brucellosis-endemic countries, health systems are weak and passively-acquired official data underestimate the true disease burden.CONCLUSIONS: High quality research is essential for an accurate assessment of disease burden, particularly in Eastern Europe, the Asia-Pacific, Central and South America and Africa where data are lacking. Providing formal epidemiological and statistical training to researchers is essential for improving study quality. An integrated approach to disease surveillance involving both human health and veterinary services would allow a better understand of disease dynamics at the animal-human interface, as well as a more cost-effective utilisation of resources

    Moderate and heavy metabolic stress interval training improve arterial stiffness and heart rate dynamics in humans

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    Traditional continuous aerobic exercise training attenuates age-related increases of arterial stiffness, however, training studies have not determined whether metabolic stress impacts these favourable effects. Twenty untrained healthy participants (n = 11 heavy metabolic stress interval training, n = 9 moderate metabolic stress interval training) completed 6 weeks of moderate or heavy intensity interval training matched for total work and exercise duration. Carotid artery stiffness, blood pressure contour analysis, and linear and non-linear heart rate variability were assessed before and following training. Overall, carotid arterial stiffness was reduced (p  0.05). This study demonstrates the effectiveness of interval training at improving arterial stiffness and autonomic function, however, the metabolic stress was not a mediator of this effect. In addition, these changes were also independent of improvements in aerobic capacity, which were only induced by training that involved a high metabolic stress

    Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects and tissue-specific enrichment of eQTLs

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    We performed genome-wide meta-analysis of lipid traits on three samples of Mexican and Mexican American ancestry comprising 4,383 individuals and followed up significant and highly suggestive associations in three additional Hispanic samples comprising 7,876 individuals. Genome-wide significant signals were observed in or near CELSR2, ZNF259/APOA5, KANK2/DOCK6 and NCAN/MAU2 for total cholesterol, LPL, ABCA1, ZNF259/APOA5, LIPC and CETP for HDL cholesterol, CELSR2, APOB and NCAN/MAU2 for LDL cholesterol and GCKR, TRIB1, ZNF259/APOA5 and NCAN/MAU2 for triglycerides. Linkage disequilibrium and conditional analyses indicate that signals observed at ABCA1 and LIPC for HDL cholesterol and NCAN/MAU2 for triglycerides are independent of previously reported lead SNP associations. Analyses of lead SNPs from the European Global Lipids Genetics Consortium (GLGC) dataset in our Hispanic samples show remarkable concordance of direction of effects as well as strong correlation in effect sizes. A meta-analysis of the European GLGC and our Hispanic datasets identified five novel regions reaching genome-wide significance: two for total cholesterol (FN1 and SAMM50), two for HDL cholesterol (LOC100996634 and COPB1) and one for LDL cholesterol (LINC00324/CTC1/PFAS). The top meta-analysis signals were found to be enriched for SNPs associated with gene expression in a tissue-specific fashion, suggesting an enrichment of tissue-specific function in lipid-associated loci

    Population Structure of Hispanics in the United States: The Multi-Ethnic Study of Atherosclerosis

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    Using ∼60,000 SNPs selected for minimal linkage disequilibrium, we perform population structure analysis of 1,374 unrelated Hispanic individuals from the Multi-Ethnic Study of Atherosclerosis (MESA), with self-identification corresponding to Central America (n = 93), Cuba (n = 50), the Dominican Republic (n = 203), Mexico (n = 708), Puerto Rico (n = 192), and South America (n = 111). By projection of principal components (PCs) of ancestry to samples from the HapMap phase III and the Human Genome Diversity Panel (HGDP), we show the first two PCs quantify the Caucasian, African, and Native American origins, while the third and fourth PCs bring out an axis that aligns with known South-to-North geographic location of HGDP Native American samples and further separates MESA Mexican versus Central/South American samples along the same axis. Using k-means clustering computed from the first four PCs, we define four subgroups of the MESA Hispanic cohort that show close agreement with self-identification, labeling the clusters as primarily Dominican/Cuban, Mexican, Central/South American, and Puerto Rican. To demonstrate our recommendations for genetic analysis in the MESA Hispanic cohort, we present pooled and stratified association analysis of triglycerides for selected SNPs in the LPL and TRIB1 gene regions, previously reported in GWAS of triglycerides in Caucasians but as yet unconfirmed in Hispanic populations. We report statistically significant evidence for genetic association in both genes, and we further demonstrate the importance of considering population substructure and genetic heterogeneity in genetic association studies performed in the United States Hispanic population

    Genome-wide association meta-analysis of fish and EPA plus DHA consumption in 17 US and European cohorts

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    Background Regular fish and omega-3 consumption may have several health benefits and are recommended by major dietary guidelines. Yet, their intakes remain remarkably variable both within and across populations, which could partly owe to genetic influences. Objective To identify common genetic variants that influence fish and dietary eicosapentaenoic acid plus docosahexaenoic acid (EPA+DHA) consumption. Design We conducted genome-wide association (GWA) meta-analysis of fish (n = 86,467) and EPA+DHA (n = 62,265) consumption in 17 cohorts of European descent from the CHARGE (Cohorts for Heart and Aging Research in Genomic Epidemiology) Consortium Nutrition Working Group. Results from cohort-specific GWA analyses (additive model) for fish and EPA+DHA consumption were adjusted for age, sex, energy intake, and population stratification, and meta-analyzed separately using fixed-effect meta-analysis with inverse variance weights (METAL software). Additionally, heritability was estimated in 2 cohorts. Results Heritability estimates for fish and EPA+DHA consumption ranged from 0.13-0.24 and 0.12-0.22, respectively. A significant GWA for fish intake was observed for rs9502823 on chromosome 6: each copy of the minor allele (Freq(A) = 0.015) was associated with 0.029 servings/day (similar to 1 serving/month) lower fish consumption (P = 1.96x10(-8)). No significant association was observed for EPA+DHA, although rs7206790 in the obesity-associated FTO gene was among top hits (P = 8.18x10(-7)). Post-hoc calculations demonstrated 95% statistical power to detect a genetic variant associated with effect size of 0.05% for fish and 0.08% for EPA+DHA. Conclusions These novel findings suggest that non-genetic personal and environmental factors are principal determinants of the remarkable variation in fish consumption, representing modifiable targets for increasing intakes among all individuals. Genes underlying the signal at rs72838923 and mechanisms for the association warrant further investigation.Peer reviewe
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