DEVELOPMENT AND TENDENCIES IN THE ORGANIZATION OF HYGIENIC AND EPIDEMIOLOGIC INSPECTION OF VARNA

An investigation of the organization of the Hygienic and Epidemiologic Inspection of Varna (HEI-Varna), its structural development and changes in the volume of the accomplished activity, staff policy, and necessary equipment was carried out. The initial structure of the establishment of HEI-Varna included two departments. It was then perfectioned and developed into 12 medical divisions. The Ministry of Heallth abrogated the current Statute-book for the activity and the structure of the HEI and suggested a new project for discussion by the regional inspections. There is a trend towards an increasing number of the objects to be investigated which are situated on the territory supervised by the HEI-Varna. The number of the checks-up and examinations enhances which is related with the greater amount of the objects resulting from the new socio-economic conditions. The staff security of the hygienic and epidemiologic service of the population is performed by 264 employees that is by 10 % less in comparison with that in 1997. One-fifth of the medical personnel members are physicians while 58,54 % of them have already acquired a narrow medical speciality

LOCALIZATION OF PULMONARY THROMBOEMBOLISM - AN IMPORTANT PROGNOSTIC FACTOR

The prognosis of pulmonary thromboembolism is a serious challenge for the clinicians. A total of 967 patients with pulmonary thromboembolism, 511 males and 456 females at a mean age of 60,1 ±13,7 years were analyzed. A special protocol consisting of 52 parameters was used to define their prognostic value. A non-invasive diagnostic algorithm based on symptoms, ECG, pulmonary roentgenography, perfusion scintigraphy, spiral scan, pulmoangiography, or on autopsy was applied. A prognostic index was elaborated by means of multifactorial analysis of the parameters of prognostic significance concerning the risk of lethal outcome. The localization of the pulmonary thromboembolism as determined by using spiral C T can effectively be used for patients' risk stratification

Analysis of environmental influences in nuclear half-life measurements exhibiting time-dependent decay rates

In a recent series of papers evidence has been presented for correlations between solar activity and nuclear decay rates. This includes an apparent correlation between Earth-Sun distance and data taken at Brookhaven National Laboratory (BNL), and at the Physikalisch-Technische Bundesanstalt (PTB). Although these correlations could arise from a direct interaction between the decaying nuclei and some particles or fields emanating from the Sun, they could also represent an "environmental" effect arising from a seasonal variation of the sensitivities of the BNL and PTB detectors due to changes in temperature, relative humidity, background radiation, etc. In this paper, we present a detailed analysis of the responses of the detectors actually used in the BNL and PTB experiments, and show that sensitivities to seasonal variations in the respective detectors are likely too small to produce the observed fluctuations

Quasi two-dimensional antiferromagnet on a triangular lattice RbFe(MoO4)2

RbFe(MoO4)2 is a rare example of a nearly two-dimensional Heisenberg antiferromagnet on a triangular lattice. Magnetic resonance spectra and magnetization curves reveal that the system has a layered spin structure with six magnetic sublattices. The sublattices within a layer are arranged in a triangular manner with the magnetization vectors 120 degree apart. The H-T phase diagram, containing at least five different magnetic phases is constructed. In zero field, RbFe(MoO4)2 undergoes a phase transition at T_N=3.8 K into a non-collinear triangular spin structure with all the spins confined in the basal plane. The application of an in-plane magnetic field induces a collinear spin state between the fields H_c1=47 kOe and H_c2=71 kOe and produces a magnetization plateau at one-third of the saturation moment. Both the ESR and the magnetization measurements also clearly indicate an additional first-order phase transition in a field of 35 kOe. The exact nature of this phase transition is uncertain.Comment: 9 pages incl 11 figure

Self-Evolving Data Cloud-Based PID-Like Controller for Nonlinear Uncertain Systems

In this article, a novel self-evolving data cloud-based proportional integral derivative (PID) (SEDCPID) like controller is proposed for uncertain nonlinear systems. The proposed SEDCPID controller is constructed by using fuzzy rules with nonparametric data cloud-based antecedence and PID-like consequence. The antecedent data clouds adopt the relative data density to represent the fuzzy firing strength of input variables instead of the explicit design of the membership functions in the classical sense. The proposed SEDCPID controller has the advantages of evolving structure and adapting parameter concurrently in an online manner. The density and distance information of data clouds are proposed to achieve the addition and deletion of data clouds and also a stable recursive method is proposed to update the parameters of the PID-like subcontrollers for the fast convergence performance. Based on the Lyapunov stability theory, the stability of the proposed controller is proven and the proof shows the tracking errors converge to a small neighborhood. Numerical and experimental results illustrate the effectiveness of the proposed controller in handling the uncertain nonlinear dynamic systems

Forbush decrease observed by SEVAN particle detector network on November 4, 2021

On November 3-4 2021, an interplanetary coronal mass injection (ICME) hits the magnetosphere, sparking a strong G3-class geomagnetic storm and auroras as far south as California and New Mexico. All detectors of the SEVAN network registered a Forbush decrease (FD) of 5-10 percentdeep in 1 minute time series of count rates. We present the results of a comparison of Fd registered on mountain altitudes on Aragats (Armenia), Lomnicky Stit (Slovakia), Musala (Bulgaria), and at sea level DESY (Hamburg, Germany), and in Mileshovka, Czechia. We present as well purity and barometric coefficients of different coincidences of SEVAN detector layers on Aragats. We demonstrate disturbances of the near-surface electric (NSEF) and geomagnetic fields at the arrival of the ICME on Earth

Clinical significance and change in the degree of mitral insufficiency after TAVI

Introduction: Hemodynamically signifi cant mitral regurgitation (MR) occurs in up to 20-30% of patients with high-grade aortic stenosis (AC) indicated for transcatheter aortic valve implantation (TAVI). Despite the establishment of the method as a standard in the treatment of high-risk patients for surgery worldwide and the growing number of patients treated interventionally, behavior in concomitant signifi cant MR continues to be a diagnostic and therapeutic challenge. The decision to intervene on multiple valves must take into account the additional surgical risk of the combined procedures. Signifi cant MR is associated with a worse prognosis in both surgical and interventional treatment. With high operative risk and signifi cant MR, TAVI is a possible solution due to the proven reduction in severity in a signifi cant proportion of patients. The aim of this paper is to evaluate the impact of signifi cant secondary MR on mortality and rate change after TAVI. Material and methods: The article is a retrospective analysis of 50 patients with high-grade symptomatic aortic stenosis who underwent successful TAVI. Patients were followed for a period of 1 year and were divided into two major groups – no signifi cant MR (0.1 degree) and those with signifi cant secondary MR (≥ grade 2). Overall mortality, cardiovascular mortality, functional class of heart failure according to the NYHA classifi cation, ejection fraction and need for rehospitalizations weremonitored. Conclusions: Hemodynamically signifi cant secondary MR, concomitant high-grade AC before TAVI undergoes positive dynamics in a signifi cant proportion of patients postprocedurally and should be considered when deciding on a therapeutic strategy by the Heart team. The worsening of signifi cant secondary MI in the studied patients is associated with 30-day and one-year cardiovascular mortality and the need for rehospitalization, which is consistent with data that the prognosis is important not only the presence of signifi cant secondary MR, but its dynamics after TAVI

DEMONSTRATION OF PROTEIN HYDROGEN BONDING NETWORK APPLICATION TO MICROELECTRONICS

Model of hydrogen bonding networks in active site of b-lactamase during the last intermediate EY of acylenzyme reaction semicycle is presented. The I-V characteristics of each hydrogen bond are calculated following Marcus theory and theory of protein electrostatics. Simulations showed that HBN characteristics are similar to the characteristics of microelectronic devices such as amplifier, signal modulator, triangular pulse source. The results demonstrated the analogy of HBNs in the active site of β-lactamase protein to microelectronic integrated circuit with multiple outputs each with different characteristics

Transition Radiation Spectroscopy with Prototypes of the ALICE TRD

We present measurements of the transition radiation (TR) spectrum produced in an irregular radiator at different electron momenta. The data are compared to simulations of TR from a regular radiator.Comment: 4 pages, 5 Figures, Proceedings for "TRDs for the 3rd millennium" (Sept. 4-7, 2003, Bari, Italy