Some operators that preserve the locality of a pseudovariety of semigroups

It is shown that if V is a local monoidal pseudovariety of semigroups, then K(m)V, D(m)V and LI(m)V are local. Other operators of the form Z(m)(_) are considered. In the process, results about the interplay between operators Z(m)(_) and (_)*D_k are obtained.Comment: To appear in International Journal of Algebra and Computatio

Development of a Novel Nanotextured Titanium Implant. An Experimental Study in Rats.

This animal study evaluated the osseointegration level of a new nanotextured titanium surface produced by anodization. Ti-cp micro-implants (1.5 mm diameter by 2.5 mm in length) divided into two groups: titanium nanotextured surface treatment (Test Group) and acid etched surface treatment (Control Group). Surface characterization included morphology analysis using scanning electron microscopy and wettability by measuring contact angle. Sixteen Wistar rats were submitted to two micro implants surgical placement procedures. In each rat, one type of micro implant placed in each tibia. The animals sacrificed after two (T1) and six weeks (T2) post-implantation. After the euthanasia, tibias processed for histomorphometric analysis, which allowed the evaluation of bone to implant contact (BIC) and the bone area fraction occupancy between the threads (BAFO). Our surface analysis data showed that the Control Group exhibited an irregular and non-homogenous topography while the Test Group showed a nanotextured surface. The Test Group showed higher wettability (contact angle = 5.1 ± 0.7°) than the Control Group (contact angle = 75.5 ± 4.6°). Concerning the histomorphometric analysis results for T1, Control and Test groups showed BIC percentages of 41.3 ± 15.2% and 63.1 ± 8.7% (p < 0.05), respectively, and for BAFO, 28.7 ± 13.7% and 54.8 ± 7.5%, respectively (p < 0.05). For T2, the histomorphometric analysis for Control and Test groups showed BIC percentages of 51.2 ± 11.4% and 64.8 ± 7.4% (p < 0.05), respectively and for BAFO, 36.4 ± 10.3% and 57.9 ± 9.3% (p < 0.05), respectively. The findings of the current study confirmed that the novel nanotextured surface exhibited superior wettability, improved peri-implant bone formation, and expedited osseointegration

Trajetorias: a dataset of environmental, epidemiological, and economic indicators for the Brazilian Amazon

The Trajetorias dataset is a harmonized set of environmental, epidemiological, and poverty indicators for all municipalities of the Brazilian Legal Amazon (BLA). This dataset is the result of a scientific synthesis research initiative conducted by scientists from several natural and social sciences fields, consolidating multidisciplinary indicators into a coherent dataset for integrated and interdisciplinary studies of the Brazilian Amazon. The dataset allows the investigation of the association between the Amazonian agrarian systems and their impacts on environmental and epidemiological changes, furthermore enhancing the possibilities for understanding, in a more integrated and consistent way, the scenarios that affect the Amazonian biome and its inhabitants.This work was funded by the Brazilian Research Council (CNPQ MCTIC-SÍNTESE EM BIODIVERSIDADE E SERVIÇOS ECOSSISTÊMICOS-SINBIOSE, process 442357/2019-2). We are grateful to the Synthesis Center on Biodiversity and Ecosystem Services (SinBiose), funded by the Brazilian Research Council, for providing the opportunity for the development of this work. CC, AM, RML, and AD are also grateful to the National Socio-Environmental Synthesis Center (SESYNC) for providing the intellectual environment that stimulated the conception of the present work, as part of the project Development, environmental degradation, and disease spread in the Brazilian Amazon led by Andres Baeza and Mercedes Pascual. We would like to extend a special thanks to Professor Francisco de Assis Costa, from the Pará Federal University (UFPA) for sharing his data on the technological trajectories in the municipalities of the Amazon biome and for his generous discussions and support. We also extend our special thanks to Alexandre Gontijo, Flavio Coelho and Marcelle Chagas, for fruitful discussions during the project.Peer Reviewed"Article signat per 15 autors/es: Ana C. Rorato, Ana Paula Dal’Asta, Raquel Martins Lana, Ricardo B. N. dos Santos, Maria Isabel S. Escada, Camila M. Vogt, Tatiana Campos Neves, Milton Barbosa, Cecilia S. Andreazzi, Izabel C. dos Reis, Danilo A. Fernandes, Mônica da Silva-Nunes, Anielli R. de Souza, Antonio M. V. Monteiro & Claudia T. Codeço "Postprint (published version

Unveiling biological activities of marine fungi: the effect of sea salt

There is an urgent need for new substances to overcome current challenges in the health sciences. Marine fungi are known producers of numerous compounds, but the manipulation of growth conditions for optimal compound production can be laborious and time-consuming. In Portugal, despite its very long coastline, there are only a few studies on marine fungi. From a collection of Portuguese marine fungi, we screened for antimicrobial, antioxidant, enzymatic, and cytotoxic activities. Mycelia aqueous extracts, obtained by high pressure-assisted extraction, and methanolic extracts of culture media showed high antioxidant, antimicrobial, and cytotoxic activities. The mycelium extracts of Cladosporium rubrum showed higher antioxidant potential compared to extracts from other fungi. Mycelia and culture media extracts of Aspergillus affinis and Penicillium lusitanum inhibited the growth of Staphylococcus aureus, Kocuria rhizophila, Enterococcus faecalis, Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa, including multiresistant strains. Penicillium lusitanum and Trichoderma aestuarinum inhibited the growth of clinical strains of Candida albicans, C. glabrata, C. parapsilosis, and C. tropicalis. All extracts from culture media were cytotoxic to Vero cells. Sea salt induced alterations in the mycelium's chemical composition, leading to different activity profiles.info:eu-repo/semantics/publishedVersio

Influência da agitação no crescimento de nanotubos de TiO2 na superfície de discos de titânio comercialmente puro

As estratégias atuais no design de biomateriais incluem a alteração das propriedades da superfície do biomaterial para direcionar sistematicamente o comportamento celular. O titânio é o material mais prevalente para uso em implantes devido às suas propriedades mecânicas. Modificações na superfície de titânio podem otimizar a osseointegração de um implante modulando a resposta imunossupressora, acelerando o processo de cicatrização e reduzindo o tempo de tratamento. O crescimento de nanotubos de TiO2 através da anodização pode alterar as propriedades da superfície do titânio comercialmente puro, permitindo uma melhor resposta quando inserido no corpo humano. Objetivo do presente trabalho foi o crescimento de nanotubos de TiO2 na superfície de discos de titânio comercialmente puro e a redução do tempo de anodização, com agitação durante a oxidação anódica, tensão de 30V e eletrólito composto por 90-10% (v/v) de etilenoglicol-H2O e 1% NH4F (m/m). Para determinar a melhor intensidade de agitação foi estabelecido um tempo de 20 minutos. A classificação da intensidade da agitação foi feita pelo método de observação, classificada como fraca, moderada e vigorosa. Para determinar o melhor tempo de oxidação anódica, foi estabelecida intensidade de agitação moderada. O tempo de anodização deve permitir que a estrutura se reorganize e aumente o grau de autoorganização, assim, foram estabelecidos tempos de 20, 30 e 40 minutos. Em seguida, as amostras foram submetidas à calcinação em forno mufla EDG com taxa de aquecimento de 5ºC/minuto, mantida por 1 hora a 450ºC. A morfologia da superfície foi analisada por microscopia eletrônica de varredura (MEV), ângulo de contato e difração de raios X (DRX).Palavras-chave: Agitação. Anodização. Biomateriais. Titânio.

Experiência do centro hospitalar de lisboa ocidental

Introduction: Although rare, angioedema is an adverse event of the renin–angiotensin–aldosterone system inhibitors (RAAi) that can be fatal due to airway obstruction. Objective: The aim of this study was to describe these episodes in patients referred to a tertiary care hospital in Lisbon, Portugal. Methods: Retrospective observational study. Inclusion criteria: patients diagnosed with angioedema of the face and upper airway, under treatment with RAAi; exclusion criteria: patients diagnosed with angioedema associated to urticaria or hypersensitivity to nonsteroidal anti-inflammatory drugs. Results 49 patients were reviewed, 23 of which were female, median age of 67 years old (min=28; máx=93). Angiotensin-converting-enzyme inhibitors (ACEi) were related to the event in 77.55% of the cases (n = 38), angiotensin II receptor blockers (ARBs) in 18.37% (n=9) and a combination of the two drugs in 4.08%(n=2). The episodes were located to the face region in 44.9% of the cases (n=22); to the airway in 34.7% (n=17); and a combination of the two in 20.4% (n= 10). Patients resort to an emergency department in 63.3% of the cases (n=31). Tracheotomy was necessary in one patient. Conclusions: The diagnosis and management of angioedema related to the RAAi represents a challenge. Although ACEi are more frequently associated with the episodes, ARBs cannot be considered as a safe alternative.publishersversionpublishe