2,526 research outputs found
Discrete Charge Dielectric Model of Electrostatic Energy
Studies on nanoscale materials merit careful development of an electrostatics
model concerning discrete point charges within dielectrics. The discrete charge
dielectric model treats three unique interaction types derived from an external
source: Coulomb repulsion among point charges, direct polarization between
point charges and their associated surface charge elements, and indirect
polarization between point charges and surface charge elements formed by other
point charges. The model yields the potential energy, U(N), stored in a general
point charge system differing from conventional integral formulations,
and , in a manner
significant to the treatment of few electron systems.Comment: 1 figure, 2 parts, ep
Novel statistical methodology reveals that hip shape is associated with incident radiographic hip osteoarthritis among African American women
Hip shape is a risk factor for the development of hip osteoarthritis (OA), and current methods to assess hip shape from radiographs are limited; therefore this study explored current and novel methods to assess hip shape
New brown dwarf candidates in the Pleiades
We have performed deep, wide-field imaging on a ~0.4 deg^2 field in the
Pleiades (Melotte 22). The selected field was not yet target of a deep search
for low mass stars and brown dwarfs. Our limiting magnitudes are R ~ 22mag and
I ~ 20mag, sufficient to detect brown dwarf candidates down to 40MJ. We found
197 objects, whose location in the (I, R - I) color magnitude diagram is
consistent with the age and the distance of the Pleiades. Using CTK R and I as
well as JHK photometry from our data and the 2MASS survey we were able to
identify 7 new brown dwarf candidates. We present our data reduction technique,
which enables us to resample, calibrate, and co-add many images by just two
steps. We estimate the interstellar extinction and the spectral type from our
optical and the NIR data using a two-dimensional chi^22 fitting.Comment: submitted to AN 37 pages (two long tables), 14 Figure
Recommended from our members
Erratum: Observation of Measurement-Induced Entanglement and Quantum Trajectories of Remote Superconducting Qubits (Physical Review Letters (2014) 112 170501)
Impact of generic alendronate cost on the cost-effectiveness of osteoporosis screening and treatment
Introduction: Since alendronate became available in generic form in the Unites States in 2008, its price has been decreasing. The objective of this study was to investigate the impact of alendronate cost on the cost-effectiveness of osteoporosis screening and treatment in postmenopausal women. Methods: Microsimulation cost-effectiveness model of osteoporosis screening and treatment for U.S. women age 65 and older. We assumed screening initiation at age 65 with central dual-energy x-ray absorptiometry (DXA), and alendronate treatment for individuals with osteoporosis; with a comparator of "no screening" and treatment only after fracture occurrence. We evaluated annual alendronate costs of 800; outcome measures included fractures; nursing home admission; medication adverse events; death; costs; quality-adjusted life-years (QALYs); and incremental cost-effectiveness ratios (ICERs) in 2010 U.S. dollars per QALY gained. A lifetime time horizon was used, and direct costs were included. Base-case and sensitivity analyses were performed. Results: Base-case analysis results showed that at annual alendronate costs of 400 through 714 per QALY gained through 50,000/QALY at all alendronate costs evaluated. Conclusions: Osteoporosis screening followed by alendronate treatment is effective and highly cost-effective for postmenopausal women across a range of alendronate costs, and may be cost-saving at annual alendronate costs of $200 or less. © 2012 Nayak et al
Alfv\'en Reflection and Reverberation in the Solar Atmosphere
Magneto-atmospheres with Alfv\'en speed [a] that increases monotonically with
height are often used to model the solar atmosphere, at least out to several
solar radii. A common example involves uniform vertical or inclined magnetic
field in an isothermal atmosphere, for which the Alfv\'en speed is exponential.
We address the issue of internal reflection in such atmospheres, both for
time-harmonic and for transient waves. It is found that a mathematical boundary
condition may be devised that corresponds to perfect absorption at infinity,
and, using this, that many atmospheres where a(x) is analytic and unbounded
present no internal reflection of harmonic Alfv\'en waves. However, except for
certain special cases, such solutions are accompanied by a wake, which may be
thought of as a kind of reflection. For the initial-value problem where a
harmonic source is suddenly switched on (and optionally off), there is also an
associated transient that normally decays with time as O(t-1) or O(t-1 ln t),
depending on the phase of the driver. Unlike the steady-state harmonic
solutions, the transient does reflect weakly. Alfv\'en waves in the solar
corona driven by a finite-duration train of p-modes are expected to leave such
transients.Comment: Accepted by Solar Physic
Three Dimensional MHD Wave Propagation and Conversion to Alfven Waves near the Solar Surface. I. Direct Numerical Solution
The efficacy of fast/slow MHD mode conversion in the surface layers of
sunspots has been demonstrated over recent years using a number of modelling
techniques, including ray theory, perturbation theory, differential eigensystem
analysis, and direct numerical simulation. These show that significant energy
may be transferred between the fast and slow modes in the neighbourhood of the
equipartition layer where the Alfven and sound speeds coincide. However, most
of the models so far have been two dimensional. In three dimensions the Alfven
wave may couple to the magneto-acoustic waves with important implications for
energy loss from helioseismic modes and for oscillations in the atmosphere
above the spot. In this paper, we carry out a numerical ``scattering
experiment'', placing an acoustic driver 4 Mm below the solar surface and
monitoring the acoustic and Alfvenic wave energy flux high in an isothermal
atmosphere placed above it. These calculations indeed show that energy
conversion to upward travelling Alfven waves can be substantial, in many cases
exceeding loss to slow (acoustic) waves. Typically, at penumbral magnetic field
strengths, the strongest Alfven fluxes are produced when the field is inclined
30-40 degrees from the vertical, with the vertical plane of wave propagation
offset from the vertical plane containing field lines by some 60-80 degrees.Comment: Accepted for the HELAS II/ SOHO 19/ GONG 2007 Topical Issue of Solar
Physic
Micro-mechanical properties of the tendon-to-bone attachment
The tendon-to-bone attachment (enthesis) is a complex hierarchical tissue that connects stiff bone to compliant tendon. The attachment site at the micrometer scale exhibits gradients in mineral content and collagen orientation, which likely act to minimize stress concentrations. The physiological micromechanics of the attachment thus define resultant performance, but difficulties in sample preparation and mechanical testing at this scale have restricted understanding of structure-mechanical function. Here, microscale beams from entheses of wild type mice and mice with mineral defects were prepared using cryo-focused ion beam milling and pulled to failure using a modified atomic force microscopy system. Micromechanical behavior of tendon-to-bone structures, including elastic modulus, strength, resilience, and toughness, were obtained. Results demonstrated considerably higher mechanical performance at the micrometer length scale compared to the millimeter tissue length scale, describing enthesis material properties without the influence of higher order structural effects such as defects. Micromechanical investigation revealed a decrease in strength in entheses with mineral defects. To further examine structure-mechanical function relationships, local deformation behavior along the tendon-to-bone attachment was determined using local image correlation. A high compliance zone near the mineralized gradient of the attachment was clearly identified and highlighted the lack of correlation between mineral distribution and strain on the low-mineral end of the attachment. This compliant region is proposed to act as an energy absorbing component, limiting catastrophic failure within the tendon-to-bone attachment through higher local deformation. This understanding of tendon-to-bone micromechanics demonstrates the critical role of micrometer scale features in the mechanics of the tissue
- …