192 research outputs found
Recommended from our members
A comparison of methods for determining ploidy in white sturgeon (Acipenser transmontanus)
Release of sturgeon with abnormal ploidy into the wild may result in reduced fitness due to lowered fertility in the F2 and subsequent generations. Further, there is evidence that ploidy affects reproductive development and caviar yield. Therefore, the ability to accurately characterize the ploidy of white sturgeon (Acipenser transmontanus)is essential for both commercial and conservation aquaculture. This study compares nuclear volume and whole erythrocyte long-axis lengths obtained using Coulter counter and blood smears, respectively, from captive white sturgeon from populations originating in California and Idaho. We examine which method provides the most accurate, time efficient and cost-effective characterization of ploidy in this species. Results from Coulter counter and blood smears were compared to results from flow cytometry, the gold standard for genome size analysis. Previous work suggests that blood smears can distinguish between 8N (diploid)and 12N (triploid)sturgeon, but further analysis is required to see if this method can also be used to identify 10N fish and to provide robust evidence of its utility in 8N and 12N fish across populations. In this study, we demonstrated that the Coulter counter had 100% agreement with flow cytometry in ploidy assignment, while blood smears vary in their accuracy based on population. Blood smears showed a high degree of overlap in erythrocyte long-axis length between 8N and 10N individuals as well as some overlap between 10N and 12N individuals in the California fish, and a high degree of overlap between 8N and 12N individuals in the Idaho fish. Although blood smears are time-intensive and vary in their ploidy assignment accuracy, they are a low-cost technique and as such may have some utility for caviar farms attempting to identify 12N individuals in a small number of broodstock. By comparing the accuracy, efficiency and cost of these three methods, sturgeon farmers and conservation hatcheries will be able to choose the best method for their needs in determining the ploidy of their fish. We determined that Coulter counter is equally accurate to flow cytometry and is also the most time efficient method for ploidy determination in white sturgeon
Quantum Non-demolition Detection of Single Microwave Photons in a Circuit
Thorough control of quantum measurement is key to the development of quantum
information technologies. Many measurements are destructive, removing more
information from the system than they obtain. Quantum non-demolition (QND)
measurements allow repeated measurements that give the same eigenvalue. They
could be used for several quantum information processing tasks such as error
correction, preparation by measurement, and one-way quantum computing.
Achieving QND measurements of photons is especially challenging because the
detector must be completely transparent to the photons while still acquiring
information about them. Recent progress in manipulating microwave photons in
superconducting circuits has increased demand for a QND detector which operates
in the gigahertz frequency range. Here we demonstrate a QND detection scheme
which measures the number of photons inside a high quality-factor microwave
cavity on a chip. This scheme maps a photon number onto a qubit state in a
single-shot via qubit-photon logic gates. We verify the operation of the device
by analyzing the average correlations of repeated measurements, and show that
it is 90% QND. It differs from previously reported detectors because its
sensitivity is strongly selective to chosen photon number states. This scheme
could be used to monitor the state of a photon-based memory in a quantum
computer.Comment: 5 pages, 4 figures, includes supplementary materia
Non-L\'evy mobility patterns of Mexican Me'Phaa peasants searching for fuelwood
We measured mobility patterns that describe walking trajectories of
individual Me'Phaa peasants searching and collecting fuelwood in the forests of
"La Monta\~na de Guerrero" in Mexico. These one-day excursions typically follow
a mixed pattern of nearly-constant steps when individuals displace from their
homes towards potential collecting sites and a mixed pattern of steps of
different lengths when actually searching for fallen wood in the forest.
Displacements in the searching phase seem not to be compatible with L\'evy
flights described by power-laws with optimal scaling exponents. These findings
however can be interpreted in the light of deterministic searching on heavily
degraded landscapes where the interaction of the individuals with their scarce
environment produces alternative searching strategies than the expected L\'evy
flights. These results have important implications for future management and
restoration of degraded forests and the improvement of the ecological services
they may provide to their inhabitants.Comment: 15 pages, 4 figures. First version submitted to Human Ecology. The
final publication will be available at http://www.springerlink.co
Spinning Conformal Correlators
We develop the embedding formalism for conformal field theories, aimed at
doing computations with symmetric traceless operators of arbitrary spin. We use
an index-free notation where tensors are encoded by polynomials in auxiliary
polarization vectors. The efficiency of the formalism is demonstrated by
computing the tensor structures allowed in n-point conformal correlation
functions of tensors operators. Constraints due to tensor conservation also
take a simple form in this formalism. Finally, we obtain a perfect match
between the number of independent tensor structures of conformal correlators in
d dimensions and the number of independent structures in scattering amplitudes
of spinning particles in (d+1)-dimensional Minkowski space.Comment: 46 pages, 3 figures; V2: references added; V3: tiny misprint
corrected in (A.9
Distress, anxiety, and depression in cancer patients undergoing chemotherapy
BACKGROUND: Chemotherapy for cancer is an intense and cyclic treatment associated with number of side-effects. The present study evaluated the effect of chemotherapy on distress, anxiety and depression. PATIENTS AND METHODS: A total of 117 patients were evaluated by using distress inventory for cancer (DIC2) and hospital anxiety and depression scale (HADS). Majority of the patients were taking chemotherapy for solid tumors (52; 44.4%). RESULTS: The mean distress score was 24, 18 (15.38%) were found to have anxiety while 19 (16.23%) had depression. High social status was the only factor found to influence distress while female gender was the only factor found to influence depression in the present study. CONCLUSION: The study highlights high psychological morbidity of cancer patients and influence of gender on depression. Construct of distress as evaluated by DIC 2 may have a possible overlap with anxiety
Risks for Central Nervous System Diseases among Mobile Phone Subscribers: A Danish Retrospective Cohort Study
The aim of this study was to investigate a possible link between cellular telephone use and risks for various diseases of the central nervous system (CNS). We conducted a large nationwide cohort study of 420 095 persons whose first cellular telephone subscription was between 1982 and 1995, who were followed through 2003 for hospital contacts for a diagnosis of a CNS disorder. Standardized hospitalization ratios (SHRs) were derived by dividing the number of hospital contacts in the cohort by the number expected in the Danish population. The SHRs were increased by 10–20% for migraine and vertigo. No associations were seen for amyotrophic lateral sclerosis, multiple sclerosis or epilepsy in women. SHRs decreased by 30–40% were observed for dementia (Alzheimer disease, vascular and other dementia), Parkinson disease and epilepsy among men. In analyses restricted to subscribers of 10 years or more, the SHRs remained similarly increased for migraine and vertigo and similarly decreased for Alzheimer disease and other dementia and epilepsy (in men); the other SHRs were close to unity. In conclusion, the excesses of migraine and vertigo observed in this first study on cellular telephones and CNS disease deserve further attention. An interplay of a healthy cohort effect and reversed causation bias due to prodromal symptoms impedes detection of a possible association with dementia and Parkinson disease. Identification of the factors that result in a healthy cohort might be of interest for elucidation of the etiology of these diseases
Physics, Astrophysics and Cosmology with Gravitational Waves
Gravitational wave detectors are already operating at interesting sensitivity
levels, and they have an upgrade path that should result in secure detections
by 2014. We review the physics of gravitational waves, how they interact with
detectors (bars and interferometers), and how these detectors operate. We study
the most likely sources of gravitational waves and review the data analysis
methods that are used to extract their signals from detector noise. Then we
consider the consequences of gravitational wave detections and observations for
physics, astrophysics, and cosmology.Comment: 137 pages, 16 figures, Published version
<http://www.livingreviews.org/lrr-2009-2
Superconducting Nanocircuits for Topologically Protected Qubits
For successful realization of a quantum computer, its building blocks
(qubits) should be simultaneously scalable and sufficiently protected from
environmental noise. Recently, a novel approach to the protection of
superconducting qubits has been proposed. The idea is to prevent errors at the
"hardware" level, by building a fault-free (topologically protected) logical
qubit from "faulty" physical qubits with properly engineered interactions
between them. It has been predicted that the decoupling of a protected logical
qubit from local noises would grow exponentially with the number of physical
qubits. Here we report on the proof-of-concept experiments with a prototype
device which consists of twelve physical qubits made of nanoscale Josephson
junctions. We observed that due to properly tuned quantum fluctuations, this
qubit is protected against magnetic flux variations well beyond linear order,
in agreement with theoretical predictions. These results demonstrate the
feasibility of topologically protected superconducting qubits.Comment: 25 pages, 5 figure
Trait anxiety predicts disease-specific health status in early-stage breast cancer patients
The objectives of this study were to examine the differences in health status (HS) of women with breast cancer (BC) at different moments in time, and between women scoring high and not high on trait anxiety, and to identify possible predictors of HS 6 and 12 months after surgery. Patients (N = 223) completed a trait anxiety questionnaire before diagnosis. Women who received a diagnosis of BC completed a BC-specific HS questionnaire 1, 3, 6 and 12 months after surgery. ANCOVA for repeated measures and multiple regression analysis were used in the analyses. Women scoring high on trait anxiety had significant (P < .005) lower Body image, worse Future perspective and Sexual functioning, and more Side-effects than women who did not score high on trait anxiety. At 6 and 12 months after surgery, the same aspects of HS were predicted by higher trait anxiety scores. Higher scores on trait anxiety resulted in worse scores on four HS domains, indicating that there should be more attention for this group of patients, even before treatment start
- …