Integration of Assertive Community Treatment into a Residency Curriculum: The Resident\u27s Perspective

Assertive Community Treatment (ACT) is a service delivery system designed to provide long-term quality care to patients with chronic mental illnesses. A brief description of these programs is presented. These programs can provide valuable training experiences for psychiatric residents. The authors report the results of their survey of residents whose training included a rotation through these services

Hemorragia ocular intensa ocasionando cegueira em paciente com estigma falciforme que desenvolveu leptospirose. Relato de caso

This case report describes the findings of a 18 year-old black male from Bahia, a Northeastern state in Brazil, with the sickle cell trait, who developed bilateral hyphema and vitreous hemorrhage with blindness in the course of leptospirosis. The patient started to complain of blurred vision four days after the start of fever and muscular pain and approximately twelve hours after the introduction of penicillin. The severity of the leptospirosis in conjunction with sickle cell trait was considered to be the most likely explanation for this ocular complication.Este relato de caso descreve os achados em homem negro com 18 anos de idade, da Bahia, estado do nordeste do Brasil, com estigma falciforme que desenvolveu hifema bilateral e hemorragia vítrea com cegueira no curso de leptospirose. O paciente começou a se queixar de visão embaçada quatro dias após o início da febre e da dor muscular e aproximadamente 12 horas após o início da penicilina. A gravidade da leptospirose em conjunto com o estigma falciforme foi considerada a mais provável explicação para esta complicação ocular

Memória operatória em crianças surdas: estudo de alguns efeitos diferenciais

[Resumo] Este estudo procurou clarificar alguns problemas ou perturbações que as crianças surdas podem apresentar ao nível do funcionamento de alguns dos componentes da memória operatória (Baddeley e Hitch, 1974), bem como da atenção. Para avaliação da memória das crianças foram criadas provas informatizadas de memória para palavras, para números e para figuras. Para além disso foram também desenvolvidas duas provas de atenção: uma de atenção concentrada e outra de atenção distribuída. Os resultados serao analisados tendo em conta o grau de surdez das crianças e da escolaridade que possuem no momento de realização das provas

Transcriptome analysis of Taenia solium cysticerci using Open reading Frame ESTS (ORESTES)

<p>Abstract</p> <p>Background</p> <p>Human infection by the pork tapeworm <it>Taenia solium </it>affects more than 50 million people worldwide, particularly in underdeveloped and developing countries. Cysticercosis which arises from larval encystation can be life threatening and difficult to treat. Here, we investigate for the first time the transcriptome of the clinically relevant cysticerci larval form.</p> <p>Results</p> <p>Using Expressed Sequence Tags (ESTs) produced by the ORESTES method, a total of 1,520 high quality ESTs were generated from 20 ORESTES cDNA mini-libraries and its analysis revealed fragments of genes with promising applications including 51 ESTs matching antigens previously described in other species, as well as 113 sequences representing proteins with potential extracellular localization, with obvious applications for immune-diagnosis or vaccine development.</p> <p>Conclusion</p> <p>The set of sequences described here will contribute to deciphering the expression profile of this important parasite and will be informative for the genome assembly and annotation, as well as for studies of intra- and inter-specific sequence variability. Genes of interest for developing new diagnostic and therapeutic tools are described and discussed.</p

Development of biofunctional textiles by the application of resveratrol to cotton, bamboo and silk

The goal of this work was to create a new generation of greener fabrics made of natural materials. For that, resveratrol (Res), obtained from Polygonum cuspidatum extract and known to have antibacterial, antifungal, and anti-inflammatory activity, was applied by an exhaustion method to cotton, bamboo, and silk knit fabrics. The fabrics adsorption behavior was tested and the amount of Res adsorbed was determined by its decrease on the immersion solutions with time and measured by spectrophotometry at 350 nm. The maximum adsorption capacity was observed for silk and it was independent of pH conditions used (50.5 % at pH=7 and 58.3 % at pH=5 of the initial Res concentration). At acidic pH conditions, cotton adsorbed 51.2 % of Res and Bamboo adsorbed only 28.1 % in 15 min. However, neither cotton nor bamboo adsorbed Res at pH=7. The release behavior was also analyzed and the highest Res release was observed for cotton in alkaline sweat and urine mimic solutions. The lowest release was achieved by cotton in water (1.0 ng/ml). Moreover, no relation was found between the amounts of Res adsorbed or released and cell viability. In conclusion, this work shows that it is possible to obtain cotton, bamboo, and silk functionalized with resveratrol. The incorporating process here described is simple and silk-Res can be presented as a good combination

Ecotoxicological aspects related to the presence of pharmaceuticals in the aquatic environment

Pharmaceuticals are biologically active and persistent substances which have been recognized as a continuing threat to environmental stability. Chronic ecotoxicity data as well as information on the current distribution levels in different environmental compartments continue to be sparse and are focused on those therapeutic classes that are more frequently prescribed and consumed. Nevertheless, they indicate the negative impact that these chemical contaminants may have on living organisms, ecosystems and ultimately, public health. This article reviews the different contamination sources as well as fate and both acute and chronic effects on non-target organisms. An extensive review of existing data in the form of tables, encompassing many therapeutic classes is presented

Audit on the radiographers practice for CTPA performing in emergency department

ComputedTomography Pulmonary Angiography (CTPA) is a first line exam used to stratify the early risk of patients with Pulmonary embolism (PE) who is a common presentation to emergency department.The diagnosis of acute Pulmonary embolism (PE) is based on direct evidence of a thrombus in two projections, either as a filling defect or as amputation of a pulmonary arterial branch When performing CTPA, it is important for the radiographer to be aware of all aspects which can lead to an indeterminate CTPA or incorrect interpretation....info:eu-repo/semantics/publishedVersio

Vector competence for West Nile virus and St. Louis encephalitis virus (flavivirus) of three tick species of the genus Amblyomma (Acari: Ixodidae)

Many species of Amblyomma ticks are commonly found infesting wild birds in South America, where birds are important hosts for several arboviruses, such as West Nile virus (WNV) and St. Louis encephalitis virus (SLEV). In this study, WNV and SLEV transmission experiments were performed to evaluate the vector competence of three South American tick species: Amblyomma ovale, Amblyomma tigrinum, and Amblyomma tonelliae. Larval and nymphal ticks of each species were allowed to feed on chicks needle inoculated with WNV or SLEV. All three Amblyomma species acquired either WNV or SLEV through larval feeding, with infection rates varying from 3.1% to 100% for WNV and from 0% to 35.7% for SLEV in engorged larvae. Transstadial perpetuation of the viruses was demonstrated in the molted nymphs, with WNV infection rates varying from 0% to 33.7% and SLEV infection rates from 13.6% to 23.8%. Although nymphal ticks also acquired either virus through feeding, transstadial perpetuation to adult ticks was lower, with virus detection in only 3.2% of A. tigrinum and 11.5% of A. tonelliae unfed adult ticks. On the other hand, vector competence for nymphs (exposed to WNV or SLEV through larval feeding) and adult ticks (exposed to WNV or SLEV through larval or nymphal feeding) was null in all cases. Although our results indicate transstadial perpetuation of WNV or SLEV in the three tick species, the ticks were not competent to transmit these agents to susceptible hosts. The role of these ixodid tick species in the epidemiology of WNV and SLEV might be insignificant, even though at least A. ovale and A. tigrinum are frequent bird ticks in Latin America, so the virus could survive winter in the fed larvae. However, future studies are required to determine the implications that this could have, as well as analyze the vector competence of other common bird tick species in South America.Fil: Flores, Fernando Sebastián. Universidad Nacional de Córdoba. Facultad de Medicina; ArgentinaFil: Zanluca, Camila. Instituto Carlos Chagas, Curitiba;Fil: Guglielmone, Alberto Alejandro. Instituto Nacional de Tecnología Agropecuaria Eea, Rafaela; ArgentinaFil: Duarte dos Santos, Claudia N.. Instituto Carlos Chagas, Curitiba;Fil: Labruna, Marcelo B.. Universidade de Sao Paulo; BrasilFil: Diaz, Luis Adrian. Universidad Nacional de Córdoba. Facultad de Medicina; Argentina. Universidad Nacional de Córdoba; Argentin