2,767 research outputs found
Ambient Salinity and the Daily Variation of Circulating Prolactin in the Gulf Killifish Fundulus grandis
Gulf killifish were maintained in either 3â° or 35â° commercial sea salts on a LD 12:12 photoperiod regime and sampled by heart puncture at one of 6 different times of day. Maximum titers of circulating prolactin occurred at the same time of day (8h after light onset) in fish acclimated to either 3â° or 35â°. Fish acclimated to 3â° had an additional increase in serum prolactin (8h after light offset) not noted in 35â° acclimated fish
Effects of Thermocycles on Body Weight Gain and Gonadal Growth in the Goldfish, Carassius auratus
Goldfish subjected to increased temperatures at one of six different times of day had significant differences in weight gain and testicular growth depending on the time of treatment. Depending on the time of day the thermocycle was initiated, weight gain and testicular growth could be either stimulated, inhibited, or equal to that in fishes subjected to constant heat or constant cold. Heat applied during the last 4 h of darkness was particularly conducive to weight gain and testicular growth. The results of this study may have important implications for aquaculture
Temperature-Induced Phase Shift of Daily Rhythm of Serum Prolactin in Gulf Killifish
Daily variations in circulating levels of the pituitary hormone prolactin have been reported in several vertebrates, including fishes. In some animals, the 24-h rhythm changes seasonally with respect to the time of day that maximum and minimum prolactin levels occur. It has been hypothesised that this seasonal change in phase of prolactin rhythm is an important component of the mechanism controlling seasonality in vertebrates. Because water temperature is generally considered the principal environmental regulator of seasonal changes in reproduction and metabolism in many fishes, including the gulf killifish Fundulus grandis, we determined the daily rhythm of serum prolactin concentrations in fish held at temperatures that are stimulatory (20 °C) or inhibitory (28 °C) for reproductive development. We found that an increase in water temperature from 20° to 28 °C phase shifts the daily variation of serum prolactin with respect to the daily photoperiod in F. grandis
Long-term X-ray Variability Study of IC342 from XMM-Newton Observations
We presented the results of an analysis of four XMM-Newton observations of
the starburst galaxy IC342 taken over a four-year span from 2001 to 2005, with
an emphasis on investigating the long-term flux and spectral variability of the
X-ray point sources. We detected a total of 61 X-ray sources within 35'
30' of the galaxy down to a luminosity of (1-2)1037 erg s-1
depending on the local background. We found that 39 of the 61 detected sources
showed long-term variability, in which 26 of them were classified as X-ray
transients. We also found 19 sources exhibiting variations in hardness ratios
or undergoing spectral transitions among observations, and were identified as
spectral variables. In particular, 8 of the identified X-ray transients showed
spectral variability in addition to flux variability. The diverse patterns of
variability observed is indicative of a population of X-ray binaries. We used
X-ray colors, flux and spectral variability, and in some cases the optical or
radio counterparts to classify the detected X-ray sources into several stellar
populations. We identified a total of 11 foreground stars, 1 supersoft sources
(SSS), 3 quasisoft sources (QSS), and 2 supernova remnants (SNR). The
identified SSS/QSS are located near or on the spiral arms, associate with young
stellar populations; the 2 SNR are very close to the starburst nucleus where
current star formation activities are dominated. We also discovered a spectral
change in the nuclear source of IC342 for the first time by a series of X-ray
spectrum analysis.Comment: 45 pages, 6 figures accepted by Ap
Deterministic polarization chaos from a laser diode
Fifty years after the invention of the laser diode and fourty years after the
report of the butterfly effect - i.e. the unpredictability of deterministic
chaos, it is said that a laser diode behaves like a damped nonlinear
oscillator. Hence no chaos can be generated unless with additional forcing or
parameter modulation. Here we report the first counter-example of a
free-running laser diode generating chaos. The underlying physics is a
nonlinear coupling between two elliptically polarized modes in a
vertical-cavity surface-emitting laser. We identify chaos in experimental
time-series and show theoretically the bifurcations leading to single- and
double-scroll attractors with characteristics similar to Lorenz chaos. The
reported polarization chaos resembles at first sight a noise-driven mode
hopping but shows opposite statistical properties. Our findings open up new
research areas that combine the high speed performances of microcavity lasers
with controllable and integrated sources of optical chaos.Comment: 13 pages, 5 figure
Theoretical overview on high-energy emission in microquasars
Microquasar (MQ) jets are sites of particle acceleration and synchrotron
emission. Such synchrotron radiation has been detected coming from jet regions
of different spatial scales, which for the instruments at work nowadays appear
as compact radio cores, slightly resolved radio jets, or (very) extended
structures. Because of the presence of relativistic particles and dense photon,
magnetic and matter fields, these outflows are also the best candidates to
generate the very high-energy (VHE) gamma-rays detected coming from two of
these objects, LS 5039 and LS I +61 303, and may be contributing significantly
to the X-rays emitted from the MQ core. In addition, beside electromagnetic
radiation, jets at different scales are producing some amount of leptonic and
hadronic cosmic rays (CR), and evidences of neutrino production in these
objects may be eventually found. In this work, we review on the different
physical processes that may be at work in or related to MQ jets. The jet
regions capable to produce significant amounts of emission at different
wavelengths have been reduced to the jet base, the jet at scales of the order
of the size of the system orbital semi-major axis, the jet middle scales (the
resolved radio jets), and the jet termination point. The surroundings of the
jet could be sites of multiwavelegnth emission as well, deserving also an
insight. We focus on those scenarios, either hadronic or leptonic, in which it
seems more plausible to generate both photons from radio to VHE and high-energy
neutrinos. We briefly comment as well on the relevance of MQ as possible
contributors to the galactic CR in the GeV-PeV range.Comment: Astrophysics & Space Science, in press (invited talk in the
conference: The multimessenger approach to the high-energy gamma-ray
sources", Barcelona/Catalonia, in July 4-7); 10 pages, 6 figures, 2 tables
(one reference corrected
Self-reported adverse reactions in 4337 healthcare workers immunizations against novel H1N1 influenza
Purpose: The use of the 2009 H1N1 vaccine has generated much debate concerning safety issues among the general population and physicians. Therefore, we investigated the safety of an inactivated monovalent H1N1 pandemic influenza vaccine Methods: We focused on the H1N1 pandemic influenza vaccine Pandemrix(R) and applied a self reporting questionnaire in a population of healthcare workers (HCWs) and medical students at a major university hospital. Results: In total, 4337 individuals were vaccinated, consisting of 3808 HCWs and 529 medical students. The vaccination rate of the employees was higher than 40%.The majority of individuals were vaccinated in November 2009. In total, 291 of the 4337 vaccinations were reported to lead to one or more adverse reactions (6.7%). Local reactions were reported in 3.8%, myalgia and arthralgia in 3.7%, fatigue in 3.7%, headache in 3.1%. Conclusions: Our data together with available data from several national and international institutions points to a safe pandemic influenza vaccine
Spintronics: Fundamentals and applications
Spintronics, or spin electronics, involves the study of active control and
manipulation of spin degrees of freedom in solid-state systems. This article
reviews the current status of this subject, including both recent advances and
well-established results. The primary focus is on the basic physical principles
underlying the generation of carrier spin polarization, spin dynamics, and
spin-polarized transport in semiconductors and metals. Spin transport differs
from charge transport in that spin is a nonconserved quantity in solids due to
spin-orbit and hyperfine coupling. The authors discuss in detail spin
decoherence mechanisms in metals and semiconductors. Various theories of spin
injection and spin-polarized transport are applied to hybrid structures
relevant to spin-based devices and fundamental studies of materials properties.
Experimental work is reviewed with the emphasis on projected applications, in
which external electric and magnetic fields and illumination by light will be
used to control spin and charge dynamics to create new functionalities not
feasible or ineffective with conventional electronics.Comment: invited review, 36 figures, 900+ references; minor stylistic changes
from the published versio
An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics
For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic annotation data along with multi-platform molecular profiles of more than 11,000 human tumors across 33 different cancer types. TCGA clinical data contain key features representing the democratized nature of the data collection process. To ensure proper use of this large clinical dataset associated with genomic features, we developed a standardized dataset named the TCGA Pan-Cancer Clinical Data Resource (TCGA-CDR), which includes four major clinical outcome endpoints. In addition to detailing major challenges and statistical limitations encountered during the effort of integrating the acquired clinical data, we present a summary that includes endpoint usage recommendations for each cancer type. These TCGA-CDR findings appear to be consistent with cancer genomics studies independent of the TCGA effort and provide opportunities for investigating cancer biology using clinical correlates at an unprecedented scale. Analysis of clinicopathologic annotations for over 11,000 cancer patients in the TCGA program leads to the generation of TCGA Clinical Data Resource, which provides recommendations of clinical outcome endpoint usage for 33 cancer types
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