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Structuring Data for Intelligent Predictive Maintenance in Asset Management
Predictive maintenance (PdM) within asset management improves savings in operational cost, productivity, and safety management capabilities. While PdM can be administered using various methods, growing interest in Arti cial Intelligence (AI) has lead to current state of the art PdM relying on machine learning (ML) technology. Like other tools used in PdM for asset management, standards for applying ML technology for PdM are required. This work introduces a standard of practice in regards to usage of asset data to develop ML analytic tools for PdM. It provides a standard method for ensuring asset data is in a form conducive to ML algorithms, and ensuring retention of asset information necessary for optimum PdM during the data transform. In the ML domain, it has been proven through research initiatives that the data structure used to train and test ML algorithms has a great impact on their performance and accuracy. Using poorly trained models for estimation due to improper data usage, can leave some AI-based PdM tools vulnerable to high rates of inaccurate estimations. Thus, leading to value loss during an asset's life cycle.This research was supported by
the Australian Government Research Training Program Scholarship,
American Australian Association Education Fund Fellowship, National
GEM Consortium, Sustain-Owner (Sustainable Design and
Management of Industrial Assets through Total Value and Cost of
Ownership), a project sponsored by the EU Framework Programme
Horizon 2020, MSCA-RISE-2014: Marie Sk lodowska-Curie Actions
Research and Innovation Staff Exchange (Rise) (grant agreement
number 645733 Sustain-owner H2020-MSCA-RISE-2014
SPH Simulations of Negative (Nodal) Superhumps: A Parametric Study
Negative superhumps in cataclysmic variable systems result when the accretion
disc is tilted with respect to the orbital plane. The line of nodes of the
tilted disc precesses slowly in the retrograde direction, resulting in a
photometric signal with a period slightly less than the orbital period. We use
the method of smoothed particle hydrodynamics to simulate a series of models of
differing mass ratio and effective viscosity to determine the retrograde
precession period and superhump period deficit as a function of
system mass ratio . We tabulate our results and present fits to both
and versus , as well as compare the
numerical results with those compiled from the literature of negative superhump
observations. One surprising is that while we find negative superhumps most
clearly in simulations with an accretion stream present, we also find evidence
for negative superhumps in simulations in which we shut off the mass transfer
stream completely, indicating that the origin of the photometric signal is more
complicated than previously believed.Comment: 14 pages, 15 figures. Accepted for publication in MNRA
Near-Perfect Synaptic Integration by Na(v)1.7 in Hypothalamic Neurons Regulates Body Weight
Neurons are well suited for computations on millisecond timescales, but some neuronal circuits set behavioral states over long time periods, such as those involved in energy homeostasis. We found that multiple types of hypothalamic neurons, including those that oppositely regulate body weight, are specialized as near-perfect synaptic integrators that summate inputs over extended timescales. Excitatory postsynaptic potentials (EPSPs) are greatly prolonged, outlasting the neuronal membrane time-constant up to 10-fold. This is due to the voltage-gated sodium channel Nav1.7 (Scn9a), previously associated with pain-sensation but not synaptic integration. Scn9a deletion in AGRP, POMC, or paraventricular hypothalamic neurons reduced EPSP duration, synaptic integration, and altered body weight in mice. In vivo whole-cell recordings in the hypothalamus confirmed near-perfect synaptic integration. These experiments show that integration of synaptic inputs over time by Nav1.7 is critical for body weight regulation and reveal a mechanism for synaptic control of circuits regulating long term homeostatic functions
Comparative Morphology of the Penis and Clitoris in Four Species of Moles (Talpidae).
The penile and clitoral anatomy of four species of Talpid moles (broad-footed, star-nosed, hairy-tailed, and Japanese shrew moles) were investigated to define penile and clitoral anatomy and to examine the relationship of the clitoral anatomy with the presence or absence of ovotestes. The ovotestis contains ovarian tissue and glandular tissue resembling fetal testicular tissue and can produce androgens. The ovotestis is present in star-nosed and hairy-tailed moles, but not in broad-footed and Japanese shrew moles. Using histology, three-dimensional reconstruction, and morphometric analysis, sexual dimorphism was examined with regard to a nine feature masculine trait score that included perineal appendage length (prepuce), anogenital distance, and presence/absence of bone. The presence/absence of ovotestes was discordant in all four mole species for sex differentiation features. For many sex differentiation features, discordance with ovotestes was observed in at least one mole species. The degree of concordance with ovotestes was highest for hairy-tailed moles and lowest for broad-footed moles. In relationship to phylogenetic clade, sex differentiation features also did not correlate with the similarity/divergence of the features and presence/absence of ovotestes. Hairy-tailed and Japanese shrew moles reside in separated clades, but they exhibit a high degree of congruence. Broad-footed and hairy-tailed moles reside within the same clade but had one of the lowest correlations in features and presence/absence of ovotestes. Thus, phylogenetic affinity and the presence/absence of ovotestes are poor predictors for most sex differentiation features within mole external genitalia
Can sacrificial feeding areas protect aquatic plants from herbivore grazing? Using behavioural ecology to inform wildlife management
Effective wildlife management is needed for conservation, economic and human well-being objectives. However, traditional population control methods are frequently ineffective, unpopular with stakeholders, may affect non-target species, and can be both expensive and impractical to implement. New methods which address these issues and offer effective wildlife management are required. We used an individual-based model to predict the efficacy of a sacrificial feeding area in preventing grazing damage by mute swans (Cygnus olor) to adjacent river vegetation of high conservation and economic value. The accuracy of model predictions was assessed by a comparison with observed field data, whilst prediction robustness was evaluated using a sensitivity analysis. We used repeated simulations to evaluate how the efficacy of the sacrificial feeding area was regulated by (i) food quantity, (ii) food quality, and (iii) the functional response of the forager. Our model gave accurate predictions of aquatic plant biomass, carrying capacity, swan mortality, swan foraging effort, and river use. Our model predicted that increased sacrificial feeding area food quantity and quality would prevent the depletion of aquatic plant biomass by swans. When the functional response for vegetation in the sacrificial feeding area was increased, the food quantity and quality in the sacrificial feeding area required to protect adjacent aquatic plants were reduced. Our study demonstrates how the insights of behavioural ecology can be used to inform wildlife management. The principles that underpin our model predictions are likely to be valid across a range of different resource-consumer interactions, emphasising the generality of our approach to the evaluation of strategies for resolving wildlife management problems
Surface modification of HVOF thermal sprayed WC–CoCr coatings by laser treatment
In this work the affects of laser characteristics on microstructure and microhardness of high velocity oxygen fuel sprayed (HVOF) WC–CoCr coatings were investigated. The coating was deposited with a Sulzer Metco WokaJet™-400 kerosene fuel and the laser surface treatments were applied using CO2 laser with 10.6 μm wavelength. Large variations in surface properties were produced from variation in the laser processing parameters. In total, four levels of peak power (100, 200, 300 and 350 W), four levels of spot diameter (0.2, 0.4, 0.6 and 1 mm) and three levels of pulse repetition frequency (PRF) were investigated. An initial set of tests were followed by a more detailed 33 factorial design of experiments. Pulse repetition frequency and duty cycle were set in order to maintain the same overlap in the x and y directions for the raster scanned sample spot impact dimensions. Overlaps of 30% were used in the initial tests and 10% in the more detailed trials. The results have shown that care must be taken to keep the irradiance at a relatively low level compared to uncoated surfaces. High irradiance can in this case result in rough and porous surfaces. Lower levels of irradiance are shown to provide more uniform microstructures, reduced porosity and increased microhardness
P04-10. Neutralization of Tier 1 and Tier 2 pseudoviruses by human anti-V3 monoclonal antibodies
Serendipitous Kepler observations of a background dwarf nova of SU UMa type
We have discovered a dwarf nova (DN) of type SU UMa in Kepler data which is
7.0 arcsec from the G-type exoplanet survey target KIC 4378554. The DN appears
as a background source in the pixel aperture of the foreground G star. We
extracted only the pixels where the DN is present and observed the source to
undergo five outbursts -- one a superoutburst -- over a timespan of 22 months.
The superoutburst was triggered by a normal outburst, a feature that has been
seen in all DNe superoutburst observed by Kepler. Superhumps during the super
outburst had a period of 1.842+/-0.004 h and we see a transition from
disc-dominated superhump signal to a mix of disc and accretion stream impact.
Predictions of the number of DNe present in Kepler data based on previously
published space densities vary from 0.3 to 258. An investigation of the
background pixels targets would lead to firmer constraints on the space density
of DN.Comment: Accepted for publication in MNRA
Regulatory role of CD8(+ )T lymphocytes in bone marrow eosinophilopoiesis
BACKGROUND: There is a growing body of evidence to suggest that CD8(+ )T lymphocytes contribute to local allergen-induced eosinophilic inflammation. Since bone marrow (BM) responses are intricately involved in the induction of airway eosinophilia, we hypothesized that CD8(+ )T lymphocytes, as well as CD4(+ )T lymphocytes, may be involved in this process. METHODS: Several approaches were utilized. Firstly, mice overexpressing interleukin-5 (IL-5) in CD3(+ )T lymphocytes (NJ.1638; CD3(IL-5+ )mice) were bred with gene knockout mice lacking either CD4(+ )T lymphocytes (CD4(-/-)) or CD8(+ )T lymphocytes (CD8(-/-)) to produce CD3(IL-5+ )knockout mice deficient in CD4(+ )T lymphocytes (CD3(IL-5+)/CD4(-/-)) and CD8(+ )T lymphocytes (CD3(IL-5+)/CD8(-/-)), respectively. Secondly, CD3(+), CD4(+ )and CD8(+ )T lymphocytes from naïve CD3(IL-5+ )and C57BL/6 mice were adoptively transferred to immunodeficient SCID-bg mice to determine their effect on BM eosinophilia. Thirdly, CD3(IL-5+), CD3(IL-5+)/CD8(-/- )and CD3(IL-5+)/CD4(-/- )mice were sensitized and allergen challenged. Bone marrow and blood samples were collected in all experiments. RESULTS: The number of BM eosinophils was significantly reduced in CD3(IL-5+)/CD8(-/- )mice compared to CD3(IL-5+ )mice and CD3(IL-5+)/CD4(-/- )mice. Serum IL-5 was significantly higher in CD3(IL-5+)/CD4(-/- )mice compared to CD3(IL-5+ )mice but there was no difference in serum IL-5 between CD3(IL-5+)/CD4(-/- )and CD3(IL-5+)/CD8(-/- )mice. Adoptive transfer of CD8(+), but not CD4(+ )T lymphocytes from naïve CD3(IL-5+ )and C57BL/6 mice restored BM eosinophilia in immunodeficient SCID-bg mice. Additionally, allergen challenged CD3(IL-5+)/CD8(-/- )mice developed lower numbers of BM eosinophils compared to CD3(IL-5+ )mice and CD3(IL-5+)/CD4(-/- )mice. CONCLUSION: This study shows that CD8(+ )T lymphocytes are intricately involved in the regulation of BM eosinophilopoiesis, both in non-sensitized as well as sensitized and allergen challenged mice
Accretion Discs with an Inner Spiral Density Wave
In Montgomery (2009a), we show that accretion discs in binary systems could
retrogradely precess by tidal torques like the Moon and the Sun on a tilted,
spinning, non-spherical Earth. In addition, we show that the state of matter
and the geometrical shape of the celestial object could significantly affect
the precessional value. For example, a Cataclysmic Variable (CV) Dwarf Novae
(DN) non-magnetic system that shows negative superhumps in its light curve can
be described by a retrogradely precessing, differentially rotating, tilted
disc. Because the disc is a fluid and because the gas stream overflows the
tilted disc and particles can migrate into inner disc annuli, coupled to the
disc could be a retrogradely precessing inner ring that is located near the
innermost annuli of the disc. However, numerical simulations by Bisikalo et al.
(2003, 2004) and this work show that an inner spiral density wave can be
generated instead of an inner ring. Therefore, we show that retrograde
precession in non-magnetic, spinning, tilted CV DN systems can equally be
described by a retrogradely precessing and differentially rotating disc with an
attached retrogradely precessing inner spiral density wave so long as the wave
appears at the same radius as the ring and within the plane of the tilted disc.
We find that the theoretical results generated in this work agree well with the
theoretical results presented in Montgomery (2009a) and thus with the numerical
simulations and select CV DN systems in Montgomery (2009b) that may have a main
sequence secondary. Therefore, pressure effects do need to be considered in CV
DN systems that exhibit negative superhumps if the accretion discs are tilted
and have an inner spiral density wave that is in the plane of the disc
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