10 research outputs found
The prevalence and risk factors of occult stress urinary incontinence in women undergoing genitourinary prolapse surgery
- Publication venue
- Faculty of Medicine, UKM Medical Centre
- Publication date
- 01/01/2016
- Field of study
De novo stress urinary incontinence (SUI) may occur in up to 80% of clinically continent women following genitourinary prolapse surgery. This had resulted in an increase in the rate of concurrent continence surgery during prolapse repair from 38% in 2001 to 47% in 2009 in the United States. To date, there is no local data available to estimate the prevalence of occult SUI (OSUI) among Malaysian women awaiting surgery. Therefore, this study was conducted to elicit the prevalence of occult SUI and its associated risks factors in patients awaiting prolapse surgery. We retrospectively studied the records of 296 consecutive women with significant pelvic organ prolapse awaiting reconstructive repair. All patients attended the Urogynaecology Unit in Hospital Kuala Lumpur Malaysia between October 2007 and September 2011. They had undergone standardized interviews, clinical examinations and urodynamic studies. During the urodynamic testings, all prolapses were reduced using ring pessaries to elicit OSUI. Primary outcome was the prevalence of OSUI with prolapse reduction to predict possibility of developing de novo SUI following prolapse surgery. Secondary outcome was the assessment of potential risk factors for OSUI. Among the 296 women studied, 121 (40.9%) were found to have OSUI. The risk factors associated with OSUI included age, BMI, numbers of SVD, recurrent UTI, reduction of urinary flow symptoms and grade 2 to 4 central compartment prolapses. We concluded that preoperative urodynamic testing with reduction of prolapse is useful to identify women with OSUI. This is important for preoperative counselling as well as planning for one step approach of prophylactic concomitant anti-incontinence procedures during prolapse surgery in order to avoid postoperative de novo SUI
The effect of rebound exercise and treadmill walking on the quality of life for patients with non-insulin-dependent type 2 diabetes
- Author
- AA Motala
- AE Carter
- AH Al-Shehri
- AL Dunn
- AM Jacobson
- AM Kriska
- AM Stys
- American Diabetes Association
- American Thoracic Society
- C Jenkinson
- EL GonzĂĄlez
- G Roglic
- J Hahl
- J Jensen
- JC Chan
- Jibril M. Nuhu
- JN Myers
- KJ McInnis
- M Javanbakht
- M Walker
- MA Testa
- ME Maruish
- MI Harris
- MJ Karvonen
- MM Engelgau
- NG Boule
- NJ Fortuin
- P Zimmet
- PO Lim
- R Kisan
- R KlevsgÄrd
- R Rubin
- RD Reid
- RR Rubin
- S Colagiuri
- S Wild
- Sonill S. Maharaj
- SQ Ardito
- SR Colberg
- SS Shapiro
- TA Bauer
- TW Rowland
- V Joshi
- WH Polonsky
- WH Polonsky
- WR Sukala
- WT Garvey
- Y Nakawatase
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Alterations in glycosaminoglycan concentration and sulfation during chondrocyte maturation
- Author
- A Boyd
- A Oldberg
- AH Reddi
- AL Arsenault
- AL Boskey
- APL Kwan
- AR Poole
- AR Poole
- B Bernard de
- B Caterson
- B Ecarot-Charrier
- BH Schofield
- BH Thorp
- C Farquharson
- C Riddell
- CC Chen
- D Heinegard
- DD Dziewiatkowski
- FP Reinholt
- GK Hunter
- GK Hunter
- H Mehmet
- H Muir
- J Appleton
- J Chayen
- J Dunham
- J Scherft
- JA Buckwalter
- JA Buckwalter
- JA Weatherell
- JC Pita
- JC Smith
- JE Scott
- JH Luft
- JM Sorrell
- JM Sorrell
- JP Pennypacker
- JR Couchman
- K Suzuki
- M Solursh
- M Takagi
- M Zanetti
- N Loveridge
- N Loveridge
- NL Shepard
- O Jibril
- OGP Isaksson
- P Bianco
- P Bianco
- PA Ealey
- PG Robey
- RD Campo
- RH Barckhaus
- RJ Midura
- RM Leach
- RW Orkin
- RW Orkin
- S Byers
- T Futami
- TE Hardingham
- WA Horton
- Y Matsui
- Y Sommarin
- Z Horne
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Site suitability evaluation of an old operating landfill using AHP and GIS techniques and integrated hydrogeological and geophysical surveys
- Author
- A Afzali
- A Aghanabati
- A Aghanabati
- A Al-Hanbali
- A Babalola
- A Beskese
- A Darvishzadeh
- A Elahi
- A Foroughian
- A Ishizaka
- A Motevalian
- Abdolreza Ghods
- AG Shetwan
- AH Davami
- AS Mahini
- ATW Chu
- B Feizizadeh
- B Mansouri
- C Bernstone
- C Daniel
- C Daniel
- CA Bana e Costa
- CK Singh
- CL Hwang
- EH Forman
- EM Martonne De
- EPA (U.S. Environmental Protection Agency)
- ESRI
- F Shams Fallah
- F Sobouti
- FL Xu
- G Khanlari
- G Nabatian
- G Tchobanoglous
- G Wang
- GA Kiker
- GA Mendoza
- IA Chandio
- Iman Monsef
- J Franek
- J Malczewski
- JD Azimi Jibril
- JK Ravalico
- KA Eldrandaly
- KS Gundogdu
- LD Hopkins
- M Ahmadi
- M Anane
- M Aruldoss
- M Eskandari
- M Eskandari
- M Eskandari
- M Masoudi
- M Moeinaddini
- M Moeinaddini
- M MutlutĂŒrk
- M Raghimi
- M Torabi-Kaveh
- M Uyan
- M Yazdani
- M Zadeh
- MA Abdoli
- Masoud Saatsaz
- MI YeĆilnacar
- Mostafa Rahmani
- MS Abessi
- MS Hassanvand
- N Alavi
- PV Gorsevski
- RR Yager
- S Bahrani
- S Leao
- S Opricovic
- S Zoras
- SM Monavari
- Statistical Center of Iran
- TD Kontos
- TD Kontos
- TL Nyerges
- TL Saaty
- TL Saaty
- TL Saaty
- TL Saaty
- TL Saaty
- TL Saaty
- TL Saaty
- TL Saaty
- TL Saaty
- USDA S
- V Akbari
- VF Nascimento
- VL Hauser
- Y Chen
- ZG Rahmat
- Ć Ćener
- Ć Ćener
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Newcastle disease in Nigeria: epizootiology and current knowledge of circulating genotypes
- Author
- A Czeglédi
- A Fusaro
- A Kammon
- A Panda
- A Samuel
- A Uthrakumar
- AA Adeyemo
- AA Owoade
- AE Salihu
- AEJ Okoh
- AG Ambali
- AG Balami
- AH Jibril
- AM Wakawa
- AM Wakawa
- AO Olabode
- C Abolnik
- C Terregino
- CC Fernandes
- CE Perroncito
- CJ Snoeck
- CJ Snoeck
- CJ Snoeck
- CK Ojeh
- CL Afonso
- D Kolakofsky
- DG Diel
- DI Hassan
- DJ Alexander
- DJ Alexander
- DK Byarugaba
- DO Oluwayelu
- DR Nawathe
- EC Okwor
- ES Haruna
- ES Haruna
- EW Aldous
- FC Kraneveld
- FD Adu
- FD Adu
- FF-X Briand
- G Cattoli
- GON Echeonwu
- H Liu
- H Liu
- HD Hill
- HM Mai
- HO Olabode
- I Shittu
- I Shittu
- I Shittu
- J Abraham-Oyiguh
- J Ibu
- J Lawal
- JA Nwanta
- JA Nwanta
- JO Okoye
- K Ganar
- K Majiyagbe
- K Tamura
- L Saâidu
- L Saâidu
- L Susta
- LW Macpherson
- MA Oyekunle
- MA Sadiq
- MF Ducatez
- MM Chellappa
- MM Radwan
- NA Oranusi
- NL Hines
- O Fatumbi
- O Leeuw de
- O Nwankiti
- O Onunkwo
- OA Fagbohun
- OF Maminiaina
- ON Ameji
- OO Fatunmbi
- OS Leeuw de
- P Solomon
- P Solomon
- PJ Miller
- PJ Miller
- PJ Miller
- R Fringe
- R Servan de Almeida
- RA Lamb
- RM Balarabe
- RS Almeida de
- S Anzaku
- S Borm Van
- S Hu
- S Xiao
- S-H Kim
- S-H Kim
- SA Anzaku
- SB Oladele
- SK Samal
- T Doyle
- T Fentie
- T Joannis
- T Manchang
- U Musa
- W Hassan
- YA Geidam
- Z Huang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Preparation of MgO for Removal of Dyes and Heavy Metal from Aqueous Solution: Facially Controlling the Morphology, Kinetic, Isotherms and Thermal Dynamic Investigations
- Author
- Al-Degs YS El-Barghouthi MI, El-Sheikh AH, Walker GM.
- Anantha RK Kota S.
- Ansari R Delavar AF.
- Banerjee S Chattopadhyaya MC.
- Chien HC.
- Dhaouadi H Touati HCF.
- Dotto GL Pinto AA.
- Freundlich HMF.
- Ghaedi M Rahimi M r, Ghaedi AM, Tyagi I, Agarwal S, Gupta VK.
- Gode F Pehlivan E.
- Goscianska J Pietrzak R.
- Guo Y Deng J, Zhu J, Zhou X, Bai R.
- Haldorai Y Shim J-J.
- Holkar CR Jadhav AJ, Pinjari DV, Mahamuni NM, Pandit AB.
- Hussin F Abnisa F, Issabayeva G, Aroua MK.
- Jibril M Poh LS, Evuti AM.
- Jïżœrup L.
- Kamari A Ngah WSW, Chong MY, Cheah ML.
- Kim Y-H Tuan VA, Park M-K, Lee C-H.
- Kumar N Reddy L, Parashar V, Ngila JC.
- Landaburu-Aguirre J Pongrïżœcz E, Perïżœmïżœki P, Keiski RL.
- Langmuir I.
- Mahmoud HR El-Molla SA, Saif M.
- Mahmoud HR Ibrahim SM, El-Molla SA.
- Malik PK.
- Malik PK.
- Mironyuk IF Gunïżœko VM, Povazhnyak MO, Zarko VI, Chelyadin VM, Leboda R, Skubiszewska-Zieba J, Janusz W.
- Mittal A Kurup L, Mittal J.
- Mittal A Mittal J, Kurup L.
- Mohamed RM Shawky A, Mkhalid I A.
- Mohsen-Nia M Montazeri P, Modarress H.
- Moussavi G Mahmoudi M.
- Rotte NK Yerramala S, Boniface J, Srikanth VVSS.
- Shao Y Wang X, Kang Y, Shu Y, Sun Q, Li L.
- Temkin MI.
- Venkatesha TG Viswanatha R, Arthoba Nayaka Y, Chethana BK.
- Vu A-T Jiang S, Ho K, Lee JB, Lee C-H.
- Vu A-T Jiang S, Kim Y-H, Lee C-H.
- Wang S Ariyanto E.
- Wawrzkiewicz M Hubicki Z.
- Yang X Li Y, Du Q, Sun J, Chen L, Hu S, Wang Z, Xia Y, Xia L.
- Publication venue
- 'Indian Society for Education and Environment'
- Publication date
- Field of study
Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS-CoV-2 pandemic.
- Author
- Aawsaj Y
- Abad Gurumeta A
- Abad-Motos A
- Abate E
- Abatini C
- Abbadessa F
- Abbas AM
- Abbassi-Ghadi N
- Abbott D
- Abbott T
- Abbott TEF
- Abd Elazeem HAS
- Abdalla M
- Abdallah M
- Abdelaal SA
- Abdeldayem H
- Abdelkarem MM
- Abdelkarim M
- Abdelmajeed A
- Abdelrahman A
- Abdelrahman S
- Abdelsamed A
- Abdou M
- Abdulkareem A
- Abdulwahed E
- Abdur-Rahman L
- Abel MK
- Abellan M
- Abosamak NE
- Abou Chaar MK
- Abou-Khalil J
- Abouassi A
- Aboulkassem H
- Abreu da Silva A
- Abu Za'nouneh FJ
- Abu J
- Abu-Nayla I
- Abubakar A
- Abukhalaf S
- Acebes Garcia F
- Achalandabaso Boira M
- Acher A
- Acrich E
- Adamina M
- Adamina M
- Adamoli L
- Addae-Boateng E
- Ademuyiwa AO
- Aderombi A
- Adeyeye A
- Adiamah A
- Adishesh M
- Agapov M
- Agarwal A
- Aggarwal A
- Aghayeva A
- Agilinko J
- Agnes A
- Agostini C
- Agoston P
- Agrawal A
- Agresta F
- Aguado H
- Aguzzoli L
- Ahad S
- Ahmadi N
- Ahmed NR
- Ahmeidat A
- Ahn JH
- Aiken T
- Aime A
- Ajlan A
- Akalin M
- Akaydin E
- Akeel N
- Akgor U
- Akhtar MA
- Akilli H
- Akin E
- Akkour K
- Akkulak M
- Akmenkalne L
- Al Abdallah M
- Al Abdel S
- Al Awwad S
- Al Habes H
- Al Maadany FS
- Al Raddadi R
- AL Sayed M
- Al-Habib A
- Al-Habsi R
- Al-Ishaq Z
- Al-Khayal K
- Al-Masri M
- Al-Mohammad A
- Al-mukhtar A
- Al-Najjar H
- Al-omishy H
- Al-Sarireh B
- Al-Tamimi Y
- Alaa S
- AlAamer O
- Aladeojebi A
- Alakaloko F
- Alam F
- Alam N
- Alam R
- Alameer E
- Alamri A
- Alamri A
- Alanbuki A
- Alatar A
- Alawneh F
- Alazawi D
- Albertsmeier M
- Albertsmeiers M
- Albi Martin B
- Alburakan A
- Alcaide Matas F
- Alconchel F
- Aldayri Z
- Aldecoa Ansorregui I
- Alderson D
- Aldokali N
- Aleksic L
- Alemanno G
- Alexoudi V
- Alfaro-Goldaracena A
- Alfieri S
- Alga A
- Alghamdi M
- Alhalal H
- Alhamed A
- Alharthi M
- Alharthi R
- Alhassan B
- Alhassan N
- Alhefdhi A
- Ali AK
- Ali M
- Ali MF
- Ali S
- Aliyeva Z
- Aljanadi F
- Aljiffry M
- Alkadeeki GZ
- Alkarak S
- Allemand C
- Allison J
- Almalik O
- Almasri M
- Almeciga A
- Almeida A
- Almeida AC
- Almeida JI
- Almgla N
- Almond M
- Almond M
- Alnumani T
- Alobeed O
- Alomair A
- Alonso de la Fuente N
- Alonso Poza A
- Alonso-Lamberti L
- Alotaibi N
- Alqannas M
- Alresaini F
- Alriyees L
- Alsaif A
- Alsaif F
- Alsalamah R
- Alsaraireh O
- Alselaim N
- Alser O
- Alshaar M
- Alshahrani M
- Alshammari S
- Alshareea E
- Alsharif F
- Alshaygy I
- Alshryda S
- Alsobhi S
- Althobaiti W
- Altintoprak F
- Alurralde C
- Alvarez E
- Alvarez MR
- Alyami M
- Alzamanan M
- Amaral MJ
- Ameerally P
- Amira G
- Amonkar S
- Amorim E
- Ampollini L
- Amrani L
- Anania G
- Anastasi A
- Anchuelo Latorre J
- Andaleeb U
- Andaya V
- Andrade AK
- Andrade R
- Andrijasevic S
- Aneke IA
- Ang K
- Angele M
- Angelo M
- Angelou D
- Angelou K
- Annamalai S
- Annessi V
- Ansarin M
- Anthoulakis C
- Antic A
- Antic S
- Antonakis P
- Antoniades K
- Antonopoulou MI
- Anula R
- Anwar S
- Anzak A
- Aoun S
- Aprile A
- Aquila F
- Aragon Achig EJ
- Aremu I
- Aremu M
- Aresu G
- Aribi N
- Aribi S
- Arican C
- Arif T
- Arigoni M
- Arikan AE
- Arkadopoulos N
- Arkha Y
- Armao T
- Armatura G
- Arminio A
- Arnaud AP
- Arrangoiz R
- Arrowsmith L
- Artigues E
- Arulanantham A
- Asaad P
- Ascensao J
- Ashcroft J
- Ashmore C
- Ashoush F
- ASiT AS
- Askari A
- Asqalan A
- Assaf M
- Assalaarachchi H
- Asti E
- Astreidis I
- Athanasakis E
- Athanasiou A
- Athayde Nemesio R
- Atherton R
- Athwal R
- Atici DS
- Atta R
- Attia D
- Augestad KM
- Australasian T
- Avci EK
- Avlund T
- Awad S
- Ayasra F
- Ayasra F
- Ayasra Y
- Aydin C
- Ayhan A
- Ayman A
- Ayorinde J
- Aytac E
- Ayub B
- Ayubi A
- Azam M
- Azamat IF
- Azevedo C
- Azevedo J
- Azevedo J
- Azevedo P
- Azizeldine MG
- Azizi A
- Azzam AY
- Baaij J
- Babar MS
- Baca B
- Bachler T
- Bacic G
- Bacon A
- Badalamenti G
- Badellino E
- Badra R
- Baena Sanfeliu E
- Baeza Pintado N
- Bagraith K
- Baia C
- Baia M
- Baiao JM
- Baietti AM
- Baig M
- Bailon M
- Bajomo O
- Baker A
- Baker C
- Baker O
- Bakmaz B
- Bakolas G
- Balabel M
- Balakrishnan A
- Balasubramaniam D
- Balasubramanian I
- Baldari L
- Baldi C
- Baldini E
- Balercia P
- Balik E
- Ballabio M
- Ballal M
- Ballouhey Q
- Baloyiannis I
- Bambina F
- Ban VS
- Bandara GBK
- Bandiera A
- Bandovas JP
- Banerjee A
- Bankhead-Kendall BK
- Bankhead-Kendall BK
- Banky B
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- Baptista VH
- Barabasz M
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- Barrett-Brown ZM
- Barrios O
- Barry C
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- Barry M
- Bartalucci B
- Bartolini I
- Bartolucci P
- Bascarevic V
- Basendowah M
- Bashir Y
- Bass G
- Bassi C
- Bates H
- Bath M
- Batistotti P
- Batjer HH
- Batstone M
- Batstone M
- Battista MJ
- Bauer M
- Baumber R
- Baxevanidou K
- Baxter K
- Bayazeed SA
- Bayhan Z
- Beamish A
- Beard D
- Beasley N
- Beatson K
- Becerra Garcia FC
- Bechri H
- Becker R
- Beech N
- Bekele D
- Bekheit M
- Belcher E
- Belia F
- Belkhadir ZH
- Bellacci A
- Bellanti L
- Belli A
- Bello J
- Bellora P
- Belluco C
- Beltramini GA
- Beltran de Heredia J
- Belvedere A
- Benavides Buleje JA
- Benkabbou A
- Bennetts J
- Benson O
- Benson RA
- Benson RA
- Bergamini C
- Bergeat D
- Bergonzani M
- Bernal-Sprekelsen JC
- Bernante P
- Bernardi D
- Bernasconi M
- Bernon M
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- Berselli M
- Bertelli G
- Bertoglio P
- Bertolani E
- Bertoli G
- Bescos C
- Beswick D
- Bettoni J
- Betz CS
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- Beyer K
- Beyrne C
- Bezede C
- Bhalla A
- Bhangu A
- Bhangu A
- Bhangu AA
- Bhangu AA
- Bhasin S
- Bhatti MI
- Biala M
- Bianchi MF
- Bianchini M
- Bianco F
- Bianco F
- Biasini M
- Biasoni D
- Bichoo R
- Biel JR
- Bigay K
- Bilgin IA
- Bille A
- Bin Nasser A
- Bin Traiki T
- Biondi A
- Bisagni P
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- Bissolotti G
- Blackwell L
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- Blanco-Colino R
- Blanco-Colino R
- Blas Laina JL
- Blatt A
- Blazer D
- Blazquez Martin A
- Boal M
- Bobinski M
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- Boddaert G
- Boddy A
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- Boettcher A
- Bogani G
- Bogdanovic I
- Bokhari A
- Boland M
- Bolster-van Eenennaam M
- Bolt J
- Bonavina G
- Bonavina L
- Bonci E
- Bond-Smith G
- Bondurri A
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- Borges F
- Borges N
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- Borgonovo G
- Bork U
- Borroni G
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- Bouche P
- Boucher S
- Bouliaris K
- Boulton A
- Bourke G
- Boussedra S
- Boutall A
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- Boutros M
- Boutros M
- Bowden J
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- Boyd-Carson H
- Boyle C
- Boyle T
- Bozanovic T
- Bozkirli B
- Bozkurt E
- Bozkurt MA
- Brachini G
- Bradshaw L
- Bradulskis S
- Bramis K
- Brana I
- Branquinho A
- Brar A
- Bratt D
- Bravo Infante R
- Breda D
- Breen KA
- Breheret R
- Breik O
- Bretherton C
- Brewer H
- Brian E
- Bright T
- Bristow R
- Brito da Silva F
- Brixton G
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- Brocklehurst M
- Bromage S
- Brooke-Smith M
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- Brunelli A
- Brunelli A
- Brunocilla E
- Brunt A
- Bruscino A
- Bruzzaniti P
- Buarque IL
- Budacan A
- Buddingh K
- Bueno Canones AD
- Buerba GA
- Bugra D
- Bulathsinhala S
- Bumbasirevic U
- Burahee A
- Burg S
- Burgan D
- Burgess C
- Burke J
- Burke J
- Burnside N
- Busch C
- Bussu F
- Buta M
- Butt U
- Butt W
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- Byrne M
- Bywater E
- Cabezudo Noguera SF
- Cadenelli P
- Cadwell-Sneath S
- Cagigal Ortega EP
- Cagigas Fernandez C
- Cahill J
- Caiado A
- Caimari B
- Caina Ruiz R
- Caird S
- Cairncross L
- Caja Vivancos P
- Cakmak G
- Calabro M
- Callanan D
- Calvo Espino P
- Camacho C
- Camillo' A
- Caminsky N
- Campagnaro T
- Campain N
- Campbell W
- Campisi G
- Canas-Martinez A
- Candiani M
- Candotti G
- Canhoto C
- Cano A
- Cano-Valderrama O
- Canonico G
- Canotilho R
- Cantalejo Diaz M
- Cao H
- Capelli P
- Capezzuoli L
- Capitan-Morales L
- Capizzi V
- Capoglu R
- Capolupo GT
- Carabias A
- Caram EL
- Carannante F
- Carcoforo P
- Cardoso N
- Cardoso P
- Caricato M
- Carrano FM
- Carrasco Prats M
- Carroll P
- Carta AG
- Carter J
- Caruana EJ
- Caruana EJ
- Caruana EJ
- Caruso J
- Carvello MM
- Casati M
- Casetti L
- Casiraghi T
- Cassinotti E
- Castano-Leon AM
- Castillejos-Molina RA
- Catala Bauset JC
- Catarzi L
- Cato LD
- Cavaleiro S
- Cavalle Busquets P
- Cayetano Paniagua L
- Cazador Labat M
- Cecchini L
- Cecconello I
- Cecire J
- Celebi F
- Celik H
- Cellerino P
- Cenciarelli S
- Ceranic M
- Ceretti PA
- Cervellera M
- Cervera I
- Ceyhan GO
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- Publication venue
- Br J Surg
- Publication date
- 11/11/2020
- Field of study
BACKGROUND: Surgical services are preparing to scale up in areas affected by COVID-19. This study aimed to evaluate the association between preoperative SARS-CoV-2 testing and postoperative pulmonary complications in patients undergoing elective cancer surgery. METHODS: This international cohort study included adult patients undergoing elective surgery for cancer in areas affected by SARS-CoV-2 up to 19 April 2020. Patients suspected of SARS-CoV-2 infection before operation were excluded. The primary outcome measure was postoperative pulmonary complications at 30 days after surgery. Preoperative testing strategies were adjusted for confounding using mixed-effects models. RESULTS: Of 8784 patients (432 hospitals, 53 countries), 2303 patients (26.2 per cent) underwent preoperative testing: 1458 (16.6 per cent) had a swab test, 521 (5.9 per cent) CT only, and 324 (3.7 per cent) swab and CT. Pulmonary complications occurred in 3.9 per cent, whereas SARS-CoV-2 infection was confirmed in 2.6 per cent. After risk adjustment, having at least one negative preoperative nasopharyngeal swab test (adjusted odds ratio 0.68, 95 per cent confidence interval 0.68 to 0.98; Pâ=â0.040) was associated with a lower rate of pulmonary complications. Swab testing was beneficial before major surgery and in areas with a high 14-day SARS-CoV-2 case notification rate, but not before minor surgery or in low-risk areas. To prevent one pulmonary complication, the number needed to swab test before major or minor surgery was 18 and 48 respectively in high-risk areas, and 73 and 387 in low-risk areas. CONCLUSION: Preoperative nasopharyngeal swab testing was beneficial before major surgery and in high SARS-CoV-2 risk areas. There was no proven benefit of swab testing before minor surgery in low-risk areas
Elective Cancer Surgery in COVID-19âFree Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study
- Author
- Aawsaj Y
- Abad Gurumeta A
- Abad-Motos A
- Abate E
- Abatini C
- Abbadessa F
- Abbas AM
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- Abbott D
- Abbott T
- Abbott Tom EF
- Abd Elazeem HAS
- Abdalla M
- Abdallah M
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- Abdel Jalil R
- Abdeldayem H
- Abdelkader Salama I
- Abdelkarem MM
- Abdelkarim M
- Abdelmajeed A
- Abdelrahman A
- Abdelrahman S
- Abdelsamed A
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- Abdulkareem A
- Abdulwahed E
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- Abosamak NE
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- on behalf of the COVIDSurg Collaborative
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- Yıldırım A
- Yildiz A
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- Yousof EA
- Youssef A
- Youssef M
- Yurttas C
- YĂĄnez C
- YĂŒksel E
- Zacharoulis D
- Zafar SN
- Zakai D
- Zakaria AD
- Zakaria R
- Zakaria Z
- Zambelli MF
- Zambon M
- Zamora L
- Zamvar V
- Zani S
- Zanotti S
- Zanus G
- Zapardiel I
- Zarabini AG
- Zegarac M
- ZeliÄ M
- Zeller N
- Zengin AK
- Zerbib P
- Zervas K
- Zese M
- Zhang H
- Zivanovic M
- Zivkovic M
- Zizzo M
- Zografos C
- Zonta S
- Zorrilla OrtĂșzar J
- Zourntou S
- Zouzoulas D
- Zubaidi A
- Zullo A
- Ăngelo M
- ĂlgĂ„ A
- ĂapoÄlu R
- Ăelebi F
- Ăolak E
- Ăfner D
- Ăhlberger L
- ĂÄĂŒcĂŒ H
- ĂberrĂŒck L
- Äoza I
- Ć imko K
- Ć ÄepanoviÄ V
- ĆœateckĂœ J
- ĐĐ°ĐŒĐ°Đ»ĐŸĐČ Đ
- Publication venue
- American Society of Clinical Oncology
- Publication date
- 01/01/2021
- Field of study
Enhanced infection prophylaxis reduces mortality in severely immunosuppressed HIV-infected adults and older children initiating antiretroviral therapy in Kenya, Malawi, Uganda and Zimbabwe: the REALITY trial
- Author
- Abach J
- Abdallah J
- Abdallah S
- Abdallah S
- Aberle-Grasse J
- Abimiku A
- Abishev A
- Abongomera G
- Aboud M
- Aboud M
- Abramovitz D
- Abrams E
- Abrams E
- Abrams E
- Abrams E
- Abravaya K
- Abreu L
- Achra A
- Adera F
- Adetokunboh O
- Adeyemi O
- Adeyemi O
- Adipo T
- Affolabi D
- Agegnehu D
- Agius P
- Agolory S
- Agot K
- Agot K
- Agovi A-A
- Aguiar P
- Aguilar-Martinez J
- Agutu C
- Ahmed M
- Ahmed R
- Ahmed S
- Ahmed S
- Ahmed S
- Aizire J
- Ajibola G
- Ajok S
- Albert-Hope C
- Alejos B
- Alexander G
- Alicea C
- Allen H
- Allen M
- Allen S
- Allen S
- Allen S
- Alloui C
- Altice F
- Altice F
- Amara R
- Ambani A
- Ambrose K
- Amico R
- Amin J
- Amin T
- Amole C
- Amoros I
- Anahtar M
- Ananworanich J
- Ananworanich J
- Ancuta P
- Andama A
- Anderegg N
- Anderson A
- Anderson A
- Anderson E
- Anderson J
- Anderson J
- Anderson S
- Andersson M
- Andrade A
- Andrew E
- Andrew P
- Andrew P
- Andrews L
- Angel J
- Angelidou K
- Anglaret X
- Anoma C
- Ansari A
- Apetrei C
- Apetrei C
- Apetrei C
- Apetrei C
- Apetrei C
- Apollon A
- Apondi E
- Aptekar S
- Ardiet D
- Arellano G
- Arenas-Pinto A
- Arhel N
- Armstrong D
- Arthos J
- Artz L
- Arunmanakul A
- Asari V
- Asege L
- Asiimwe S
- Asiimwe S
- Asiimwe S
- Asokan M
- Aspin C
- Athiambo M
- Atuhumuza E
- Atujuna M
- Audet C
- Auerbach J
- Auld A
- Aung P
- Aurpibul L
- Aurpibul L
- Avalos A
- Avihingsanon A
- Avihingsanon A
- Avihingsanon A
- Awori Q
- Awotwi E
- Ayala V
- Ayalew M
- Ayaya S
- Ayieko J
- Ayieko J
- Ayieko J
- Aylott A
- Azar M
- Azbel L
- Azizuyo B
- Babiker A
- Babikhina K
- Back D
- Badjé A
- Baeten J
- Baeten J
- Baeten J
- Baeten J
- Baeten J
- Baeten J
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- Baghazal A
- Bagley Z
- Bah-sow O
- Baijnath P
- Bailey R
- Bailey R
- Bajos N
- Bajracharya A
- Bajunirwe F
- Bakowska E
- Bakwalufu J
- Balestre E
- Balkan S
- Balzer L
- Bamba A
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- Banda K
- Bandason T
- Bangsberg
- Baral S
- Baral S
- Baral S
- Baral S
- Baral S
- Barasa M
- Barber M
- Barbour R
- Barde A
- Bardeguez A
- Barihuta T
- Barker C
- Barnabas R
- Barnes P
- Barnighausen T
- Baron D
- Barone M
- Barr D
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- Barrington C
- Barron P
- Baruwa E
- Basar M
- Bassett I
- Bassett J
- Bassett J
- Bastos F
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- Baum M
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- Bautista-Arredondo S
- Bautista-Arredondo S
- Bavinton B
- Bavinton B
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- Bazin B
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- Beckham S
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- Beletsky L
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- Boyes M
- Bozinoff N
- Bozzi G
- Bradley J
- Brahmbhatt H
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- Brewster-Lee D
- Brezak A
- Brigham F
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- Brill I
- Brill I
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- Brocca-Cofano E
- Brocca-Cofano E
- Brocca-Cofano E
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- Brooks-Pollock E
- Brothers J
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- Brown G
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- BrÀu N
- Bucek A
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- Bukenya D
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- Bulterys M
- Bulya N
- Bulya N
- Bunu A
- Burchett S
- Burgener A
- Burke S
- Burman W
- Burmeister S
- Burton R
- Burwitz B
- Busch M
- Busch M
- Busza J
- Bwakura-Dangarembizi M
- Bwakura-Dangarembizi M
- Bwana M
- Bygrave H
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- Byrd J
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- BĂ€rnighausen T
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- Capitant C
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- Carolus G
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- Chabeda S
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- Charoenying S
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- Chasanov
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- Chaudhury S
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- Chelbi-Alix M
- Chemhuru M
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- Cheng Z
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- Chidiac C
- Chigayo M
- Chihana NK
- Chikandiwa A
- Chikandiwa A
- Chikonda J
- Chileshe C
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- Zablotska I
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- Publication venue
- 'International AIDS Society'
- Publication date
- 01/01/2016
- Field of study
Meeting abstract FRAB0101LB from 21st International AIDS Conference 18â22 July 2016, Durban, South Africa.
Introduction: Mortality from infections is high in the first 6 months of antiretroviral therapy (ART) among HIVâinfected adults and children with advanced disease in subâSaharan Africa. Whether an enhanced package of infection prophylaxis at ART initiation would reduce mortality is unknown.
Methods:
The REALITY 2Ă2Ă2 factorial openâlabel trial (ISRCTN43622374) randomized ARTânaĂŻve HIVâinfected adults and children >5 years with CD4 <100 cells/mm3. This randomization compared initiating ART with enhanced prophylaxis (continuous cotrimoxazole plus 12 weeks isoniazid/pyridoxine (antiâtuberculosis) and fluconazole (antiâcryptococcal/candida), 5 days azithromycin (antiâbacterial/protozoal) and singleâdose albendazole (antiâhelminth)), versus standardâofâcare cotrimoxazole. Isoniazid/pyridoxine/cotrimoxazole was formulated as a scored fixedâdose combination. Two other randomizations investigated 12âweek adjunctive raltegravir or supplementary food. The primary endpoint was 24âweek mortality.
Results:
1805 eligible adults (n = 1733; 96.0%) and children/adolescents (n = 72; 4.0%) (median 36 years; 53.2% male) were randomized to enhanced (n = 906) or standard prophylaxis (n = 899) and followed for 48 weeks (3.8% lossâtoâfollowâup). Median baseline CD4 was 36 cells/mm3 (IQR: 16â62) but 47.3% were WHO Stage 1/2. 80 (8.9%) enhanced versus 108(12.2%) standard prophylaxis died before 24 weeks (adjusted hazard ratio (aHR) = 0.73 (95% CI: 0.54â0.97) p = 0.03; Figure 1) and 98(11.0%) versus 127(14.4%) respectively died before 48 weeks (aHR = 0.75 (0.58â0.98) p = 0.04), with no evidence of interaction with the two other randomizations (p > 0.8). Enhanced prophylaxis significantly reduced incidence of tuberculosis (p = 0.02), cryptococcal disease (p = 0.01), oral/oesophageal candidiasis (p = 0.02), deaths of unknown cause (p = 0.02) and (marginally) hospitalisations (p = 0.06) but not presumed severe bacterial infections (p = 0.38). Serious and grade 4 adverse events were marginally less common with enhanced prophylaxis (p = 0.06). CD4 increases and VL suppression were similar between groups (p > 0.2).
Conclusions:
Enhanced infection prophylaxis at ART initiation reduces early mortality by 25% among HIVâinfected adults and children with advanced disease. The pill burden did not adversely affect VL suppression. Policy makers should consider adopting and implementing this lowâcost broad infection prevention package which could save 3.3 lives for every 100 individuals treated