Marital Status and Occupation versus Serum Total Cholesterol and HDL – Cholesterol Levels in Healthy Adults from Kano Metropolis, Nigeria

The influence of marital status and occupation on serum total cholesterol (TC) and high density lipoprotein cholesterol (HDL – CH) concentrations was studied in sixty one (61) adult male and female Hausa subjects aged 20 – 50 years. Irrespective of marital status and occupation, female subjects had higher mean serum TC and HDL – CH levels than male subjects. Married subjects of both sexes had higher mean serum TC and HDL – CH levels than their non – married counterparts. Male subjects (students) had significantly (

Phytotherapy as an alternative for the treatment of human papilloma virus infections in Nigeria: a review

Human papillomavirus (HPV) has been incriminated as the causal agent of cervical cancer which has been rated as the second most common cancers among women in developing countries and seventh most common cancers in the developed world. In spite of the fact that HPV has been the major cause of cervical cancer, the dilemma lies in finding a cost-effective therapy. Approximately 291 million women are infected with HPV worldwide, 32% of whom are infected with HPV16 or HPV18. The estimated prevalence of HPV in sub-Saharan Africa is 24% and 11.7% globally. There have been studies reporting specific HPV prevalence rates in some part of Nigeria, with 37% in Abuja, 10% in Port Harcourt, and 26.3% in Ibadan. In the Nigeria population, awareness of HPV infections is low, HPV vaccines are inadequate, and the cost of HPV vaccination per person is beyond what an average citizen can afford. It has been suggested that herbal therapy such as Echinacea therapy reduces HPV replication and enhances the immune system. Although there is yet no scientific proof of the efficacy of Echinacea therapy against HPV infections, future emphasis should be placed on scientific research into this alternative therapy. There is need for more studies on development of antiviral agents against HPV, with a prospect of easy accessibility and affordability in Nigeria.Keywords: Phytotherapy; HPV; Cervical cancer; Nigeri

Integrating the HFACS Framework and Fuzzy Cognitive Mapping for In-Flight Startle Causality Analysis

This paper discusses the challenge of modeling in-flight startle causality as a precursor to enabling the development of suitable mitigating flight training paradigms. The article presents an overview of aviation human factors and their depiction in fuzzy cognitive maps (FCMs), based on the Human Factors Analysis and Classification System (HFACS) framework. The approach exemplifies system modeling with agents (causal factors), which showcase the problem space's characteristics as fuzzy cognitive map elements (concepts). The FCM prototype enables four essential functions: explanatory, predictive, reflective, and strategic. This utility of fuzzy cognitive maps is due to their flexibility, objective representation, and effectiveness at capturing a broad understanding of a highly dynamic construct. Such dynamism is true of in-flight startle causality. On the other hand, FCMs can help to highlight potential distortions and limitations of use case representation to enhance future flight training paradigms

Hot press as a sustainable direct recycling technique of aluminium: mechanical properties and surface integrity

Meltless recycling technique has been utilized to overcome the lack of primary resources, focusing on reducing the usage of energy and materials. Hot press was proposed as a novel direct recycling technique which results in astoundingly low energy usage in contrast with conventional recycling. The aim of this study is to prove the technical feasibility of this approach by characterizing the recycled samples. For this purpose, AA6061 aluminium chips were recycled by utilizing hot press process under various operating temperature (Ts = 430, 480, and 530 °C) and holding times (ts = 60, 90, and 120 min). The maximum mechanical properties of recycled chip are Ultimate tensile strength (UTS) = 266.78 MPa, Elongation to failure (ETF) = 16.129%, while, for surface integrity of the chips, the calculated microhardness is 81.744 HV, exhibited at Ts = 530 °C and ts = 120 min. It is comparable to theoretical AA6061 T4-temper where maximum UTS and microhardness is increased up to 9.27% and 20.48%, respectively. As the desired mechanical properties of forgings can only be obtained by means of a final heat treatment, T5-temper, aging after forging process was employed. Heat treated recycled billet AA6061 (T5-temper) are considered comparable with as-received AA6061 T6, where the value of microhardness (98.649 HV) at 175 °C and 120 min of aging condition was revealed to be greater than 3.18%. Although it is quite early to put a base mainly on the observations in experimental settings, the potential for significant improvement offered by the direct recycling methods for production aluminium scrap can be clearly demonstrated. This overtures perspectives for industrial development of solid state recycling processes as environmentally benign alternatives of current melting based practices

Rapid Assessment of Polio Virus Antibodies Prevalence Amongst Children in Kano State, North West Nigeria

The completion of poliomyelitis eradication is a global health emergency which must be pursued with vigour. Kano state has remained one of the epicenters for polio virus outbreaks in northern Nigeria. There is paucity of information as it relates to polio antibody prevalence amongst children in the state. Periodic serologic assessment is needed to determine the quality and effectiveness of routine vaccination campaigns carried in the state to rapidly build immunity against poliovirus. Children were randomly selected throughout the state for the assessment between Sept. 2013 and Jan. 2014. Blood samples were collected from eighty children and tested for the presence of antibodies to the three poliovirus serotypes. Indirect ELISA was used to rapidly screen for the antibodies. Epi Info 3.5.4 version was used for the data analysis. Out of the samples collected, 61 (76.3%) had antibodies to all the serotypes. While 73 (91.3%), 66 (82.5%) and 72 (90%) had antibodies to virus serotypes 1, 2 and 3 respectively. Age of the children, number of doses the children had taken and educational level of the children’s fathers were statistically significant risk factors on the prevalence of poliovirus antibodies. Access to immunization services must be improved in urban and rural areas so as to effectively reach a large number of children in those places. Effective and high quality campaigns are needed so that every eligible child is reached. Greater focus on good mobilization is also needed to reach children in households in rural areas as well as in households with children whose fathers’ educational level was low.Keywords: Kano, Prevalence, Children and Polio-antibod

Growth performance, carcass characteristics and meat yield of Boer goats fed diets containing leaves and whole parts of Andrographis paniculata

The study was conducted to determine the effect of feeding diets containing Andrographis paniculata leaves (APL), whole Andrographis paniculata plant (APWP) and a control without Andrographis paniculata (AP0), on growth performance, carcass characteristics and meat yield of 24 intact Boer bucks. The results obtained indicated that inclusion of Andrographis paniculata significantly improved feed intake, weight gain, feed efficiency and live weight. The ratios of carcass to fat, lean to bone, lean to fat, and composition of meat were also improved. In addition, there were significant differences (p<0.05) between the dietary treatments in dressing percentage and chilling loss. Goats fed on AP0 (control) had significantly higher proportions of fat and bone, as well as thicker back fat than the supplemented animals (APL and APWP). Higher gut fill in animals fed Andrographis paniculata suggested slow rate of digestion, which could have improved utilization and absorption of nutrients by the animals. Goats fed Andrographis paniculata also produced higher meat yield and relatively lower fat contents (p<0.05)

Polypharmacy, potentially serious clinically relevant drug-drug interactions, and inappropriate medicines in elderly people with type 2 diabetes and their impact on quality of life

The aim of the study is to investigate the patterns of polypharmacy, clinical-relevant drug-drug interactions (DDIs), and potentially inappropriate medicines (PIMs), and whether polypharmacy, potential serious clinically-relevant DDIs, or PIMs can be associated with low quality of life (QoL) index scores of older adults with type 2 diabetes (T2D). A cross-sectional study was conducted using data of 670 elderly T2D sub-cohort from a nationwide pharmacy-based intensive monitoring study of inception cohort of T2D in Portugal. 72.09% were found on polypharmacy (≥5 medicines). Participants on polypharmacy were mostly females (P = .0115); more obese (P = .0131); have more comorbid conditions (P < .0001); more diabetes complications (P < .0001); and use more of glucose lowering drugs (P = .0326); insulin (P < .0001); chronic medicines (P < .0001); and have higher diabetes duration (P = .0088) than those without polypharmacy. 10.59% of the participants were found to have potential serious clinically relevant DDIs. The most frequent drug-combinations were angiotensin-converting enzyme (ACE) inhibitors with angiotensin-receptor blockers (ARBs), aspirin with Selective serotonin reuptake inhibitors (SSRIs), and clopidogrel with calcium channel blockers. PIMs are found in 36.11% of the participants. The most common PIMs were benzodiazepines, long-acting sulfonylureas, and iron overdose. The adjusted multivariate models show that Polypharmacy, PIMs, and potential serious clinically relevant DDIs were associated with lower QoL index scores (OR 1.80 95% CI 1.15-2.82), (OR 1.57 95% CI 1.07-2.28), and (OR 1.34 95% CI 0.73-2.48) respectively. The study shows that polypharmacy, potential serious clinical-relevant DDIs, and PIMs may correlate with risk of reduced health related QoL outcome of older adults with T2D.publishersversionpublishe

Massive subgaleal haematoma in a 5 year old child – A case report

Subgaleal haematoma (SH) is a collection of blood between the bony skull and the loose connective tissue. It is almost a diagnosis confined to the neonatal age group with very few occurring beyond the age. Presentation could be sudden or chronic as deterioration in the cardio pulmonary status,shock, skin changes, airway obstruction and neurological sequealae.While assisted delivery with birth trauma are recognized causal factorsin the neonate, trauma to the head and blood related disorders have been reported to be major causes in older children and adults. Usually, the Small SH resolves spontaneously while the massive ones require active management; often with neuro surgical intervention. It also needs identifying the cause so as to treat and prevent a recurrence. We present a case of massive SH in a 5 year old mentally subnormal child with seizure disorder with a favourable outcome

Oil Palm Mapping Over Peninsular Malaysia Using Google Earth Engine and Machine Learning Algorithms

Oil palm plays a pivotal role in the ecosystem, environment, economy and without proper monitoring, uncontrolled oil palm activities could contribute to deforestation that can cause high negative impacts on the environment and therefore, proper management and monitoring of the oil palm industry are necessary. Mapping the distribution of oil palm is crucial in order to manage and plan the sustainable operations of oil palm plantations. Remote sensing provides a means to detect and map oil palm from space effectively. Recent advances in cloud computing and big data allow rapid mapping to be performed over large a geographical scale. In this study, 30 m Landsat 8 data were processed using a cloud computing platform of Google Earth Engine (GEE) in order to classify oil palm land cover using non-parametric machine learning algorithms such as Support Vector Machine (SVM), Classification and Regression Tree (CART) and Random Forest (RF) for the first time over Peninsular Malaysia. The hyperparameters were tuned, and the overall accuracy produced by the SVM, CART and RF were 93.16%, 80.08% and 86.50% respectively. Overall, the SVM classified the 7 classes (water, built-up, bare soil, forest, oil palm, other vegetation and paddy) the best. However, RF extracted oil palm information better than the SVM. The algorithms were compared and the McNemar's test showed significant values for comparisons between SVM and CART and RF and CART. On the other hand, the performance of SVM and RF are considered equally effective. Despite the challenges in implementing machine learning optimisation using GEE over a large area, this paper shows the efficiency of GEE as a cloud-based free platform to perform bioresource distributions mapping such as oil palm over a large area in Peninsular Malaysia