1,138 research outputs found
Recommended from our members
PREVENTING CORPORATE CRISES - STOCK-MARKET LOSSES AS A DETERRENT TO THE PRODUCTION OF HAZARDOUS PRODUCTS
Attitudes of Patients and Their Relatives Towards Artificial Intelligence in Neurosurgery
BACKGROUND: Artificial Intelligence (AI) may favorably support surgeons but may result in concern among patients and their relatives. OBJECTIVE: To evaluate attitudes of patients and their relatives towards the use of AI in neurosurgery. METHODS: In this two-stage cross-sectional survey, a qualitative survey was administered to a focus group of former patients to investigate their perception of AI and its role in neurosurgery. Five themes were identified and used to generate a case-based quantitative survey administered to inpatients and their relatives over a two-week period. Presented AI platforms were rated appropriate and acceptable using 5-point Likert scales. Demographic data was collected. A Chi Square test was performed to determine whether demographics influenced participants' attitudes. RESULTS: In the first stage, 20 participants responded. Five themes were identified: interpretation of imaging (4/20; 20%), operative planning (5/20; 25%), real-time alert of potential complications (10/20; 50%), partially autonomous surgery (6/20; 30%), fully autonomous surgery (3/20; 15%). In the second stage, 107 participants responded. The majority felt appropriate and acceptable to use AI for imaging interpretation (76.7%; 66.3%), operative planning (76.7%; 75.8%), real-time alert of potential complications (82.2%; 72.9%), and partially autonomous surgery (58%; 47.7%). Conversely, most did not feel that fully autonomous surgery was appropriate (27.1%) or acceptable (17.7%). Demographics did not have a significant influence on perception. CONCLUSIONS: The majority of patients and their relatives believed that AI has a role in neurosurgery and found it acceptable. Notable exceptions remain fully autonomous systems, with most wanting the neurosurgeon ultimately to remain in control
Resolution requirements for numerical simulations of transition
The resolution requirements for direct numerical simulations of transition to turbulence are investigated. A reliable resolution criterion is determined from the results of several detailed simulations of channel and boundary-layer transition
On duality symmetry in perturbative quantum theory
Non-compact symmetries of extended 4d supergravities involve duality
rotations of vectors and thus are not manifest off-shell invariances in
standard "second-order" formulation. To study how such symmetries are realised
in the quantum theory we consider examples in 2 dimensions where vector-vector
duality is replaced by scalar-scalar one. Using a "doubled" formulation, where
fields and their momenta are treated on an equal footing and the duality
becomes a manifest symmetry of the action (at the expense of Lorentz symmetry),
we argue that the corresponding on-shell quantum effective action or S-matrix
are duality symmetric as well as Lorentz invariant. The simplest case of
discrete Z_2 duality corresponds to a symmetry of the S-matrix under flipping
the sign of the negative-chirality scalars in 2 dimensions or phase rotations
of chiral (definite-helicity) parts of vectors in 4 dimensions. We also briefly
discuss some 4d models and comment on implications of our analysis for extended
supergravities.Comment: 21 pages, Latex v2: comments and references added v3: references and
minor comments adde
On duality symmetries of supergravity invariants
The role of duality symmetries in the construction of counterterms for
maximal supergravity theories is discussed in a field-theoretic context from
different points of view. These are: dimensional reduction, the question of
whether appropriate superspace measures exist and information about non-linear
invariants that can be gleaned from linearised ones. The former allows us to
prove that F-term counterterms cannot be E7(7)-invariant in D=4, N=8
supergravity or E6(6)-invariant in D=5 maximal supergravity. This is confirmed
by the two other methods which can also be applied to D=4 theories with fewer
supersymmetries and allow us to prove that N=6 supergravity is finite at three
and four loops and that N=5 supergravity is three-loop finite.Comment: Clarification of arguments and their consistency with higher
dimensional divergences added, e.g. we prove the 5D 4L non-renormalisation
theorem. The 4L N=6 divergence is also ruled out. References adde
Effect of base–acid properties of the mixtures of water with methanol on the solution enthalpy of selected cyclic ethers in this mixture at 298.15 K
The enthalpies of solution of cyclic ethers: 1,4-
dioxane, 12-crown-4 and 18-crown-6 in the mixture of
water and methanol have been measured within the whole
mole fraction range at T = 298.15 K. Based on the obtained
data, the effect of base–acid properties of water–
methanol mixtures on the solution enthalpy of cyclic ethers
in these mixtures has been analyzed. The solution enthalpy
of cyclic ethers depends on acid properties of water–
methanol mixtures in the range of high and medium water
contents in the mixture. Based on the analysis performed, it
can be assumed that in the mixtures of high methanol
contents, cyclic ethe
E11, generalised space-time and equations of motion in four dimensions
We construct the non-linear realisation of the semi-direct product of E11 and
its first fundamental representation at low levels in four dimensions. We
include the fields for gravity, the scalars and the gauge fields as well as the
duals of these fields. The generalised space-time, upon which the fields
depend, consists of the usual coordinates of four dimensional space-time and
Lorentz scalar coordinates which belong to the 56-dimensional representation of
E7. We demand that the equations of motion are first order in derivatives of
the generalised space-time and then show that they are essentially uniquely
determined by the properties of the E11 Kac-Moody algebra and its first
fundamental representation. The two lowest equations correctly describe the
equations of motion of the scalars and the gauge fields once one takes the
fields to depend only on the usual four dimensional space-time
Goltz syndrome (focal dermal hypoplasia) with unilateral ocular, cutaneous and skeletal features: case report
<p>Abstract</p> <p>Background</p> <p>Goltz syndrome or focal dermal hypoplasia (FDH) is an uncommon multisystem disorder. Herein, we report a typical case of FDH with unilateral ocular, cutaneous and skeletal features.</p> <p>Case Presentation</p> <p>a 4-year-old girl presented with microphthalmos and iris coloboma of the left eye, facial asymmetry, and a low-set protruding ear. Cutaneous changes included hypopigmented atrophic macules on the left side of the face, chest, abdomen and limbs. Characteristic lobster claw deformity of left hand and oligodactyly and syndactyly of left foot were present.</p> <p>Conclusions</p> <p>FDH usually affects both sides of the body. This case represents the unusual unilateral manifestation of the syndrome.</p
On the Importance of Countergradients for the Development of Retinotopy: Insights from a Generalised Gierer Model
During the development of the topographic map from vertebrate retina to superior colliculus (SC), EphA receptors are expressed in a gradient along the nasotemporal retinal axis. Their ligands, ephrin-As, are expressed in a gradient along the rostrocaudal axis of the SC. Countergradients of ephrin-As in the retina and EphAs in the SC are also expressed. Disruption of any of these gradients leads to mapping errors. Gierer's (1981) model, which uses well-matched pairs of gradients and countergradients to establish the mapping, can account for the formation of wild type maps, but not the double maps found in EphA knock-in experiments. I show that these maps can be explained by models, such as Gierer's (1983), which have gradients and no countergradients, together with a powerful compensatory mechanism that helps to distribute connections evenly over the target region. However, this type of model cannot explain mapping errors found when the countergradients are knocked out partially. I examine the relative importance of countergradients as against compensatory mechanisms by generalising Gierer's (1983) model so that the strength of compensation is adjustable. Either matching gradients and countergradients alone or poorly matching gradients and countergradients together with a strong compensatory mechanism are sufficient to establish an ordered mapping. With a weaker compensatory mechanism, gradients without countergradients lead to a poorer map, but the addition of countergradients improves the mapping. This model produces the double maps in simulated EphA knock-in experiments and a map consistent with the Math5 knock-out phenotype. Simulations of a set of phenotypes from the literature substantiate the finding that countergradients and compensation can be traded off against each other to give similar maps. I conclude that a successful model of retinotopy should contain countergradients and some form of compensation mechanism, but not in the strong form put forward by Gierer
The Sphaleron Rate in SU(N) Gauge Theory
The sphaleron rate is defined as the diffusion constant for topological
number NCS = int g^2 F Fdual/32 pi^2. It establishes the rate of equilibration
of axial light quark number in QCD and is of interest both in electroweak
baryogenesis and possibly in heavy ion collisions. We calculate the
weak-coupling behavior of the SU(3) sphaleron rate, as well as making the most
sensible extrapolation towards intermediate coupling which we can. We also
study the behavior of the sphaleron rate at weak coupling at large Nc.Comment: 18 pages with 3 figure
- …