190 research outputs found
An oscillating hydromagnetic non-Newtonian flow in a rotating system
AbstractAn exact solution of an oscillatory boundary layer flow bounded by two horizontal flat plates, one of which is oscillating in its own plane and the other at rest, is developed. The fluid and the plates are in a state of solid body rotation with constant angular velocity about the z-axis normal to the plates. The fluid is assumed to be second grade, incompressible, and electrically conducting. A uniform transverse magnetic field is applied. During the mathematical analysis, it is found that the steady part of the solution is identical to that of viscous fluid. The structure of the boundary layers is also discussed. Several known results of interest are found to follow as particular cases of the solution of the problem considered
Weighted Tradeoff between Spectral Efficiency and Energy Efficiency in Energy Harvesting Systems
This paper proposes a new power allocation scheme to jointly optimize energy efficiency (EE) and spectral efficiency (SE) of a point-to-point communication system in which the transmitter is equipped with fixed as well as energy harvesting batteries. Time switching protocol is used such that in each time frame the node either harvests energy or transmits information. Firstly, a multi-objective optimization problem which jointly optimizes EE and SE is formulated. An importance weight parameter is introduced to control the priority level between EE and SE. Secondly, the multi-objective problem is transformed into a single-objective optimization problem by using importance weight, and then solved through fractional programming. Using the Karush-Kuhn-Tucker conditions, the optimum power allocation scheme without input power constraint is developed. The ensuing solution is then generalized for system operation with average input power constraint. Closed-form expressions are derived and tested through simulations. Numerical results results are provided, and show the impact of the harvested power in improving the overall rate of the system. Also investigation is done to analyze the effect of system parameters on the achievable trade-off performance of the energy-harvesting based syste
Non-Newtonian effects in the peristaltic flow of a Maxwell fluid
We analyzed the effect of viscoelasticity on the dynamics of fluids in porous
media by studying the flow of a Maxwell fluid in a circular tube, in which the
flow is induced by a wave traveling on the tube wall. The present study
investigates novelties brought about into the classic peristaltic mechanism by
inclusion of non-Newtonian effects that are important, for example, for
hydrocarbons. This problem has numerous applications in various branches of
science, including stimulation of fluid flow in porous media under the effect
of elastic waves. We have found that in the extreme non-Newtonian regime there
is a possibility of a fluid flow in the direction {\it opposite} to the
propagation of the wave traveling on the tube wall.Comment: to Appear in Phys. Rev. E., 01 September 2001 issu
Wire coating analysis with Oldroyd 8-constant fluid by Optimal Homotopy Asymptotic Method
AbstractIn this study the wire coating in a pressure type die with the bath of Oldroyd 8-constant fluid with pressure gradient is investigated. The non-linear ordinary differential equation in dimensionless form is obtained, which is solved for the velocity profile using the Optimal Homotopy Asymptotic Method (OHAM). The effect of Dilatant constant α, the Psendoplastic constant β, and the pressure gradient on velocity distribution and shear stress is studied. Shear stress is examined under the effect of the viscosity parameter η0. Moreover, the volume flow rate and average velocity is carefully studied with changing the domain (thickness) of the polymer and varying the parameter α,β and the pressure gradient
Immunological considerations for schistosoma vaccine development: transitioning to endemic settings
Despite mass drug administration programmes with praziquantel, the prevalence of schistosomiasis remains high. A vaccine is urgently needed to control transmission of this debilitating disease. As some promising schistosomiasis vaccine candidates are moving through pre-clinical and clinical testing, we review the immunological challenges that these vaccine candidates may encounter in transitioning through the clinical trial phases in endemic settings. Prior exposure of the target population to schistosomes and other infections may impact vaccine response and efficacy and therefore requires considerable attention. Schistosomes are known for their potential to induce T-reg/IL-10 mediated immune suppression in populations which are chronically infected. Moreover, endemicity of schistosomiasis is focal whereby target and trial populations may exhibit several degrees of prior exposure as well as in utero exposure which may increase heterogeneity of vaccine responses. The age dependent distribution of exposure and development of acquired immunity, and general differences in the baseline immunological profile, adds to the complexity of selecting suitable trial populations. Similarly, prior or concurrent infections with other parasitic helminths, viral and bacterial infections, may alter immunological responses. Consequently, treatment of co-infections may benefit the immunogenicity of vaccines and may be considered despite logistical challenges. On the other hand, viral infections leave a life-long immunological imprint on the human host. Screening for serostatus may be needed to facilitate interpretation of vaccine responses. Co-delivery of schistosome vaccines with PZQ is attractive from a perspective of implementation but may complicate the immunogenicity of schistosomiasis vaccines. Several studies have reported PZQ treatment to induce both transient and long-term immuno-modulatory effects as a result of tegument destruction, worm killing and subsequent exposure of worm antigens to the host immune system. These in turn may augment or antagonize vaccine immunogenicity. Understanding the complex immunological interactions between vaccine, co-infections or prior exposure is essential in early stages of clinical development to facilitate phase 3 clinical trial design and implementation policies. Besides well-designed studies in different target populations using schistosome candidate vaccines or other vaccines as models, controlled human infections could also help identify markers of immune protection in populations with different disease and immunological backgrounds.Host-parasite interactio
Electro-osmotic flow of couple stress fluids in a microchannel propagated by peristalsis
A mathematical model is developed for electro-osmotic peristaltic pumping of a non-Newtonian liquid in a deformable micro-channel. Stokes’ couple stress fluid model is deployed to represent realistic working liquids. The Poisson-Boltzmann equation for electric potential distribution is implemented owing to the presence of an electrical double layer (EDL) in the micro-channel. Using long wavelength, lubrication theory and Debye-Huckel approximations, the linearized transformed dimensionless boundary value problem is solved analytically. The influence of electro-osmotic parameter (inversely proportional to Debye length), maximum electro-osmotic velocity (a function of external applied electrical field) and couple stress parameter on axial velocity, volumetric flow rate, pressure gradient, local wall shear stress and stream function distributions is evaluated in detail with the aid of graphs. The Newtonian fluid case is retrieved as a special case with vanishing couple stress effects. With increasing couple stress parameter there is a significant elevation in axial pressure gradient whereas the core axial velocity is reduced. An increase in electro-osmotic parameter induces both flow acceleration in the core region (around the channel centreline) and also enhances axial pressure gradient substantially. The study is relevant to simulation of novel smart bio-inspired space pumps, chromatography and medical microscale devices
Influence of scrotal bipartition on spermatogenesis yield and sertoli cell efficiency in sheep
Abstract With the objective to assess the effect of scrotal bipartition on spermatogenesis in sheep, the testes were used from 12 crossbred rams of sheep farms in the municipality of Patos, ParaĂba, Brazil, distributed into two groups: GI with six rams with scrotal bipartition, and GII with six rams without scrotal bipartition. The testicular biometry was measured and the testes were collected, fixed in Bouin and fragments were processed to obtain histological slides. The spermatogenesis yield and the Sertoli cell efficiency was estimated by counting the cells of the spermatogenetic line at stage one of the seminiferous epithelium cycle and the Sertoli cells. The results were submitted to analysis of variance with the ASSISTAT v.7.6 program and the mean values were compared by the Student-Newman-Keuls test (SNK) at 5% significance. The testicular biometric parameters did not show statistical difference (p>0.05) between the groups. The meiotic, spermatogenetic and Sertoli cell efficiency were higher in bipartitioned rams (p0.05) between GI and GII. The results indicated that there is superiority in the spermatogenetic parameters of bi-partitioned rams, suggesting that these sheep present, as reported in goats, indication of better reproductive indices
Right hemisphere dominance directly predicts both baseline V1 cortical excitability and the degree of top-down modulation exerted over low-level brain structures
© 2015 The Authors. Published by Elsevier. This is an open access article available under a Creative Commons licence.
The published version can be accessed at the following link on the publisher’s website: https://doi.org/10.1016/j.neuroscience.2015.10.045Right hemisphere dominance for visuo-spatial attention is characteristically observed in most right-handed individuals. This dominance has been attributed to both an anatomically larger right fronto-parietal network and the existence of asymmetric parietal interhemispheric connections. Previously it has been demonstrated that interhemispheric conflict, which induces left hemisphere inhibition, results in the modulation of both (i) the excitability of the early visual cortex (V1) and (ii) the brainstem-mediated vestibular–ocular reflex (VOR) via top-down control mechanisms. However to date, it remains unknown whether the degree of an individual’s right hemisphere dominance for visuospatial function can influence, (i) the baseline excitability of the visual cortex and (ii) the extent to which the right hemisphere can exert top-down modulation. We directly tested this by correlating line bisection error (or pseudoneglect), taken as a measure of right hemisphere dominance, with both (i) visual cortical excitability measured using phosphene perception elicited via single-pulse occipital trans-cranial magnetic stimulation (TMS) and (ii) the degree of trans-cranial direct current stimulation (tDCS)-mediated VOR suppression, following left hemisphere inhibition. We found that those individuals with greater right hemisphere dominance had a less excitable early visual cortex at baseline and demonstrated a greater degree of vestibular nystagmus suppression following left hemisphere cathodal tDCS. To conclude, our results provide the first demonstration that individual differences in right hemisphere dominance can directly predict both the baseline excitability of low-level brain structures and the degree of top-down modulation exerted over them
Materializing digital collecting: an extended view of digital materiality
If digital objects are abundant and ubiquitous, why should consumers pay for, much less collect them? The qualities of digital code present numerous challenges for collecting, yet digital collecting can and does occur. We explore the role of companies in constructing digital consumption objects that encourage and support collecting behaviours, identifying material configuration techniques that materialise these objects as elusive and authentic. Such techniques, we argue, may facilitate those pleasures of collecting otherwise absent in the digital realm. We extend theories of collecting by highlighting the role of objects and the companies that construct them in materialising digital collecting. More broadly, we extend theories of digital materiality by highlighting processes of digital material configuration that occur in the pre-objectification phase of materialisation, acknowledging the role of marketing and design in shaping the qualities exhibited by digital consumption objects and consequently related consumption behaviours and experiences
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