Schwingungseigenschaften der Ossikel und der Cochlea und deren Bedeutung für unser Gehör

Zusammenfassung: Untersuchungen der Bewegungen von Trommelfell und Steigbügel belegen, dass in den höheren Frequenzen komplexe, räumliche Vibrationsmuster auftreten, bei denen sich die einzelnen Elemente in sehr unterschiedlichen räumlichen Richtungen und in sehr unterschiedlichen Phasenlagen bewegen. Am Steigbügel sind eine kolbenförmige Bewegung sowie eine Rotation um die kurze und lange Steigbügelachse zu unterscheiden. Im Gegensatz zu den kolbenförmigen Schwingungen führen Rotationsbewegungen nicht zu einer Nettovolumenverschiebung der cochleären Flüssigkeit in einem gewissen Abstand von der Fußplatte. Deshalb wird aufgrund der gängigen Theorie des Hörens angenommen, dass solche Kippbewegungen keinen Einfluss auf das Gehör haben. In einer Reihe von Studien wurde jedoch qualitativ gezeigt, dass auch Kippbewegungen zu cochleärer Aktivität führen können. Weitere Forschung ist notwendig, um diesen Effekt zu quantifiziere

Aberrierende A.carotis interna als Ursache eines pulssynchronen Tinnitus: Schwierige Diagnose in der MRT?

Zusammenfassung: Wir präsentieren einen Fall eines 43 jährigen Patienten mit einseitiger sensorineuraler Schwerhörigkeit und Zufallsbefund einer aberrierende A.carotis interna im linken Mittelohr, welche einen pulsierenden Tinnitus verursacht. Das aberrierende Gefäß war inital bei einer Magnetresonanztomographie (MRT) nicht zu sehen und konnte erst mittels Computertomographie und MR-Angiographie (MRA) nachgewiesen werden. Um den aberrierenden Verlauf einer A.carotis interna zu erkennen, ist häufig neben einer konventionellen MRT eine MRA nötig, um die Diagnose zu sichern und andere Differenzialdiagnosen auszuschließe

Following Gluonic World Lines to Find the QCD Coupling in the Infrared

Using a parametrization of the Wilson loop with the minimal-area law, we calculate the polarization operator of a valence gluon, which propagates in the confining background. This enables us to obtain the infrared freezing (i.e. finiteness) of the running strong coupling in the confinement phase, as well as in the deconfinement phase up to the temperature of dimensional reduction. The momentum scale defining the onset of freezing is found both analytically and numerically. The nonperturbative contribution to the thrust variable, originating from the freezing, makes the value of this variable closer to the experimental one.Comment: 25 pages, 5 figure

High-resolution UV spectrum of the benzene—N2 van der Waals complex

The rotationally resolved spectrum of the 610 band of the S1 ← S0 electronic transition of the benzene—N2 van der Waals complex has been recorded and 119 transitions assigned. The C6H6·N2 complex, produced in a pulsed molecular beam, was detected by mass-selected two-photon two-colour ionization employing a high-resolution (ΔνUV = 100 MHz, fwhm) pulsed-amplified cw laser for the resonant intermediate excitation. The observed rotational structure is that of a rigid symmetric top with weaker additional rotational transitions most likely arising from the free internal rotation of the N2 in the plane parallel to the benzene ring. The N2 is located parallel to the benzene ring at a distance of 3.50 Å; this decreases by 45 mÅ in the excited electronic state

The Quest for Antiinflammatory and Immunomodulatory Strategies in Heart Failure

Intensive research over the last 3 decades has unequivocally demonstrated the relevance of inflammation in heart failure (HF). Despite our current and ever increasing knowledge about inflammation, the clinical success of antiinflammatory and immunomodulatory therapies in HF is still limited. This review outlines the complexity and diversity of inflammation, its reciprocal interaction with HF, and addresses future perspectives, calling for immunomodulatory therapies that are specific for factors that activate the immune system without the risk of nonspecific immune suppression

The terroir of the finch: How spatial and temporal variation shapes phenotypic traits in Darwin\u27s finches

The term terroir is used in viticulture to emphasize how the biotic and abiotic characteristics of a local site influence grape physiology and thus the properties of wine. In ecology and evolution, such terroir (i.e., the effect of space or “site”) is expected to play an important role in shaping phenotypic traits. Just how important is the pure spatial effect of terroir (e.g., differences between sites that persist across years) in comparison to temporal variation (e.g., differences between years that persist across sites), and the interaction between space and time (e.g., differences between sites change across years)? We answer this question by analyzing beak and body traits of 4388 medium ground finches (Geospiza fortis) collected across 10 years at three locations in Galápagos. Analyses of variance indicated that phenotypic variation was mostly explained by site for beak size (η2 = 0.42) and body size (η2 = 0.43), with a smaller contribution for beak shape (η2 = 0.05) and body shape (η2 = 0.12), but still higher compared to year and site-by-year effects. As such, the effect of terroir seems to be very strong in Darwin\u27s finches, notwithstanding the oft-emphasized interannual variation. However, these results changed dramatically when we excluded data from Daphne Major, indicating that the strong effect of terroir was mostly driven by that particular population. These phenotypic results were largely paralleled in analyses of environmental variables (rainfall and vegetation indices) expected to shape terroir in this system. These findings affirm the evolutionary importance of terroir, while also revealing its dependence on other factors, such as geographical isolation

Non-standard interactions using the OPERA experiment

We investigate the implications of non-standard interactions on neutrino oscillations in the OPERA experiment. In particular, we study the non-standard interaction parameter $\epsilon_{\mu\tau}$. We show that the OPERA experiment has a unique opportunity to reduce the allowed region for this parameter compared with other experiments such as the MINOS experiment, mostly due to the higher neutrino energies in the CNGS beam compared to the NuMI beam. We find that OPERA is mainly sensitive to a combination of standard and non-standard parameters and that a resulting anti-resonance effect could suppress the expected number of events. Furthermore, we show that running OPERA for five years each with neutrinos and anti-neutrinos would help in resolving the degeneracy between the standard parameters and $\epsilon_{\mu\tau}$. This scenario is significantly better than the scenario with a simple doubling of the statistics by running with neutrinos for ten years.Comment: 15 pages, 5 figures, REVTeX

The role of matter density uncertainties in the analysis of future neutrino factory experiments

Matter density uncertainties can affect the measurements of the neutrino oscillation parameters at future neutrino factory experiments, such as the measurements of the mixing parameters $\theta_{13}$ and \deltacp. We compare different matter density uncertainty models and discuss the possibility to include the matter density uncertainties in a complete statistical analysis. Furthermore, we systematically study in which measurements and where in the parameter space matter density uncertainties are most relevant. We illustrate this discussion with examples that show the effects as functions of different magnitudes of the matter density uncertainties. We find that matter density uncertainties are especially relevant for large \stheta \gtrsim 10^{-3}. Within the KamLAND-allowed range, they are most relevant for the precision measurements of \stheta and \deltacp, but less relevant for ``binary'' measurements, such as for the sign of \ldm, the sensitivity to \stheta, or the sensitivity to maximal CP violation. In addition, we demonstrate that knowing the matter density along a specific baseline better than to about 1% precision means that all measurements will become almost independent of the matter density uncertainties.Comment: 21 pages, 7 figures, LaTeX. Final version to be published in Phys. Rev.

Effects of new physics in neutrino oscillations in matter

A new flavor changing electron neutrino interaction with matter would always dominate the nu_e oscillation probability at sufficiently high neutrino energies. Being suppressed by theta_{13}, the energy scale at which the new effect starts to be relevant may be within the reach of realistic experiments, where the peculiar dependence of the signal with energy could give rise to a clear signature in the nu_e --> nu_tau channel. The latter could be observed by means of a coarse large magnetized detector by exploiting tau --> mu decays. We discuss the possibility of identifying or constraining such effects with a high energy neutrino factory. We also comment on the model independent limits on them.Comment: 11 pages, 5 figure

Momentum-Resolved Tunneling into Fractional Quantum Hall Edges

Tunneling from a two-dimensional contact into quantum-Hall edges is considered theoretically for a case where the barrier is extended, uniform, and parallel to the edge. In contrast to previously realized tunneling geometries, details of the microscopic edge structure are exhibited directly in the voltage and magnetic-field dependence of the differential tunneling conductance. In particular, it is possible to measure the dispersion of the edge-magnetoplasmon mode, and the existence of additional, sometimes counterpropagating, edge-excitation branches could be detected.Comment: 4 pages, 3 figures, RevTex