835 research outputs found
Perceptual compensation for the effects of reverberation on consonant identification: Evidence from studies with monaural stimuli
Mounting evidence suggests that listeners perceptually compensate for the adverse effects of reverberation in rooms when listening to speech monaurally. However, it is not clear whether the underlying perceptual mechanism would be at all effective in the high levels of stimulus uncertainty that are present in everyday listening. Three experiments investigated monaural compensation with a consonant identification task in which listeners heard different speech on each trial. Consonant confusions frequently arose when a greater degree of reverberation was added to a test-word than to its surrounding context, but compensation became apparent in conditions where the context reverberation was increased to match that of the test-word; here, the confusions were largely resolved. A second experiment shows that information from the test-word itself can also effect compensation. Finally, the time course of compensation was examined by applying reverberation to a portion of the preceding context; consonant identification improves as this portion increases in duration. These findings indicate a monaural compensation mechanism that is likely to be effective in everyday listening, allowing listeners to recalibrate as their reverberant environment changes
A cohort study of the associations between udder conformation, milk somatic cell count, and lamb weight in suckler ewes
A cohort study of 67 suckler ewes from 1 farm was carried out from January to May 2010 to investigate associations between udder conformation, udder half milk somatic cell count (SCC), and lamb weight. Ewes and lambs were observed at lambing. Ewe health and teat condition and lamb health and weight were recorded on 4 to 5 further occasions at 14-d intervals. At each observation, a milk sample was collected from each udder half for somatic cell counting. Two weeks after lambing, ewe udder conformation and teat placement were scored. Low lamb weight was associated with ewe SCC >400,000 cells/mL (â0.73kg), a new teat lesion 14 d previously (â0.91kg), suboptimal teat position (â1.38kg), rearing in a multiple litter (â1.45kg), presence of diarrhea at the examination (â1.19kg), and rearing by a 9-yr-old ewe compared with a 6-yr-old ewe (â2.36kg). High lamb weight was associated with increasing lamb age (0.21kg/d), increasing birth weight (1.65kg/kg at birth), and increasing number of days the ewe was given supplementary feed before lambing (0.06kg/d). High udder half SCC was associated with pendulous udders (9.6% increase in SCC/cm of drop) and greater total cross-sectional area of the teats (7.2% increase of SCC/cm2). Low SCC were associated with a heavier mean litter weight (6.7% decrease in SCC/kg). Linear, quadratic, and cubic terms for days in lactation were also significant. We conclude that poor udder and teat conformation are associated with high levels of intramammary infection, as indicated by increased SCC and that both physical attributes of the udder and SCC are linked to lamb growth, suggesting that selection of suckler ewes with better udder and teat conformation would reduce intramammary infection and increase lamb growth rate
Exploratory assessment of the relationship between dairy intensification, gender and child nutrition among smallholder farmers in Buret and Kipkelion Districts, Kenya
Multi-stimulus linear negative expansion of a breathing M(O2CR)4-node MOF
The metalâorganic framework (Me2NH2)2[Cd(NO2BDC)2] (SHF-81) comprises flattened tetrahedral Cd(O2CR)42â nodes, in which Cd(II) centres are linked via NO2BDC2â ligands (2-nitrobenzene-1,4-dicarboxylate) to give a doubly interpenetrated anionic network, with charge balanced by two Me2NH2+ cations per Cd centre resident in the pores. The study establishes that this is a twinned α-quartz-type structure (trigonal, space group P3x21, x = 1 or 2), although very close to the higher symmetry ÎČ-quartz arrangement (hexagonal, P6x22, x = 2 or 4) in its as-synthesised solvated form [Cd(NO2BDC)2]·2DMF·0.5H2O (SHF-81-DMF). The activated MOF exhibits very little N2 uptake at 77 K, but shows significant CO2 uptake at 273â298 K with an isosteric enthalpy of adsorption (ÎHads) at zero coverage of â27.4 kJ molâ1 determined for the MOF directly activated from SHF-81-DMF. A series of in situ diffraction experiments, both single-crystal X-ray diffraction (SCXRD) and powder X-ray diffraction (PXRD), reveal that the MOF is flexible and exhibits breathing behaviour with observed changes as large as 12% in the a- and b-axes (|Îa|, |Îb| 0; Îc 0). The largest change in dimensions is observed during activation/desolvation from SHF-81-DMF to SHF-81 (Îa, Îb 0; ÎV < 0). Collectively the nine in situ diffraction experiments conducted suggest the breathing behaviour is continuous, although individual desolvation and adsorption experiments do not rule out the possibility of a gating or step at intermediate geometries that is coupled with continuous dynamic behaviour towards the extremities of the breathing amplitude
Statistical Determination of Bulk Flow Motions
We present here a new parameterization for the bulk motions of galaxies and
clusters (in the linear regime) that can be measured statistically from the
shape and amplitude of the two-dimensional two-point correlation function. We
further propose the one-dimensional velocity dispersion (v_p) of the bulk flow
as a complementary measure of redshift-space distortions, which is
model-independent and not dependent on the normalisation method. As a
demonstration, we have applied our new methodology to the C4 cluster catalogue
constructed from Data Release Three (DR3) of the Sloan Digital Sky Survey. We
find v_p=270^{+433}km/s (also consistent with v_p=0) for this cluster sample
(at z=0.1), which is in agreement with that predicted for a WMAP5-normalised
LCDM model (i.e., v_p(LCDM=203km/s). This measurement does not lend support to
recent claims of excessive bulk motions (\simeq1000 km/s) which appear in
conflict with LCDM, although our large statistical error cannot rule them out.
From the measured coherent evolution of v_p, we develop a technique to
re-construct the perturbed potential, as well as estimating the unbiased matter
density fluctuations and scale--independent bias.Comment: 8 pages, 5 figure
The complement system in neurodegenerative diseases
Complement is an important component of innate immune defence against pathogens and crucial for efficient immune complex disposal. These core protective activities are dependent in large part on properly regulated complement-mediated inflammation. Dysregulated complement activation, often driven by persistence of activating triggers, is a cause of pathological inflammation in numerous diseases, including neurological diseases. Increasingly, this has become apparent not only in well-recognized neuroinflammatory diseases like multiple sclerosis but also in neurodegenerative and neuropsychiatric diseases where inflammation was previously either ignored or dismissed as a secondary event. There is now a large and rapidly growing body of evidence implicating complement in neurological diseases that cannot be comprehensively addressed in a brief review. Here, we will focus on neurodegenerative diseases, including not only the âclassicalâ neurodegenerative diseases such as Alzheimerâs disease and Parkinsonâs disease, but also two other neurological diseases where neurodegeneration is a neglected feature and complement is implicated, namely, schizophrenia, a neurodevelopmental disorder with many mechanistic features of neurodegeneration, and multiple sclerosis, a demyelinating disorder where neurodegeneration is a major cause of progressive decline. We will discuss the evidence implicating complement as a driver of pathology in these diverse diseases and address briefly the potential and pitfalls of anti-complement drug therapy for neurodegenerative diseases
The dynamic centres of infrared-dark clouds and the formation of cores
High-mass stars have an enormous influence on the evolution of the interstellar medium in galaxies, so it is important that we understand how they form. We examine the central clumps within a sample of seven infrared-dark clouds (IRDCs) with a range of masses and morphologies. We use 1-pc-scale observations from the Northern Extended Millimeter Array (NOEMA) and the IRAM 30m telescope to trace dense cores with 2.8-mm continuum, and gas kinematics in C18O, HCO+, HNC, and N2H+ (J = 1â0). We supplement our continuum sample with six IRDCs observed at 2.9âmm with the Atacama Large Millimeter/submillimeter Array (ALMA), and examine the relationships between core- and clump-scale properties. We have developed a fully automated multiple-velocity component hyperfine line-fitting code called MWYDYN which we employ to trace the dense gas kinematics in N2H+ (1â0), revealing highly complex and dynamic clump interiors. We find that parsec-scale clump mass is the most important factor driving the evolution; more massive clumps are able to concentrate more mass into their most massive cores â with a log-normally distributed efficiency of around 9 perâcent â in addition to containing the most dynamic gas. Distributions of linewidths within the most massive cores are similar to the ambient gas, suggesting that they are not dynamically decoupled, but are similarly chaotic. A number of studies have previously suggested that clumps are globally collapsing; in such a scenario, the observed kinematics of clump centres would be the direct result of gravity-driven mass inflows that become ever more complex as the clumps evolve, which in turn leads to the chaotic mass growth of their core populations
Near infrared reflectance spectroscopy for the determination of free gossypol in cottonseed meal
Gossypol is a toxic polyphenolic compound produced by the pigment glands of the cotton
plant. The free gossypol content of cottonseed meal (CSM) is commonly determined by the
American Oil Chemistsâ Society (AOCS) wet chemistry method. The AOCS method, however,
laboratory-intensive, time-consuming, and therefore, not practical for quick field analyses.
To determine if the free gossypol content of CSM could be predicted by near infrared reflectance
spectroscopy (NIRS), CSM samples were collected from all over the world. All CSM samples
were ground and a portion of each analyzed for free gossypol by the AOCS procedure (reference
data) and by NIRS (reflectance data). Both reflectance and reference data were combined in
calibration. The coefficient of determination (r2) and standard error of prediction (SEP) were
used to assess the calibration accuracy. The r2 was 0.728, and the SEP was 0.034 for the
initial calibration that included samples from all over the world. However, the r2 and SEP
improved to 0.921 and 0.014, respectively, if the calibration was made using CSM samples
only from the United States. These results indicate that a general prediction equation can be
developed to predict the free gossypol content of CSM by NIRS. From a practical standpoint,
NIRS technology provides a method for quickly assessing whether a particular batch of CSM
has a free gossypol content low enough to be suitable for use in poultry diets.This research was supported in part by grant 05-635GA from the Georgian Cotton Commission, Perry, G
Observation of a Narrow Resonance of Mass 2.46 GeV/c^2 Decaying to D_s^*+ pi^0 and Confirmation of the D_sJ^* (2317) State
Using 13.5 inverse fb of e+e- annihilation data collected with the CLEO II
detector we have observed a narrow resonance in the Ds*+pi0 final state, with a
mass near 2.46 GeV. The search for such a state was motivated by the recent
discovery by the BaBar Collaboration of a narrow state at 2.32 GeV, the
DsJ*(2317)+ that decays to Ds+pi0. Reconstructing the Ds+pi0 and Ds*+pi0 final
states in CLEO data, we observe peaks in both of the corresponding
reconstructed mass difference distributions, dM(Dspi0)=M(Dspi0)-M(Ds) and
dM(Ds*pi0)=M(Ds*pi0)-M(Ds*), both of them at values near 350 MeV. We interpret
these peaks as signatures of two distinct states, the DsJ*(2317)+ plus a new
state, designated as the DsJ(2463)+. Because of the similar dM values, each of
these states represents a source of background for the other if photons are
lost, ignored or added. A quantitative accounting of these reflections confirms
that both states exist. We have measured the mean mass differences
= 350.0 +/- 1.2 [stat] +/- 1.0 [syst] MeV for the DsJ*(2317) state, and
= 351.2 +/- 1.7 [stat] +/- 1.0 [syst] MeV for the new DsJ(2463)+
state. We have also searched, but find no evidence, for decays of the two
states via the channels Ds*+gamma, Ds+gamma, and Ds+pi+pi-. The observations of
the two states at 2.32 and 2.46 GeV, in the Ds+pi0 and Ds*+pi0 decay channels
respectively, are consistent with their interpretations as (c anti-strange)
mesons with orbital angular momentum L=1, and spin-parities of 0+ and 1+.Comment: 16 pages postscript, also available through
http://w4.lns.cornell.edu/public/CLNS, version to be published in Physical
Review D; minor modifications and fixes to typographical errors, plus an
added section on production properties. The main results are unchanged; they
supersede those reported in hep-ex/030501
Measurement of the Charge Asymmetry in
We report on a search for a CP-violating asymmetry in the charmless hadronic
decay B -> K*(892)+- pi-+, using 9.12 fb^-1 of integrated luminosity produced
at \sqrt{s}=10.58 GeV and collected with the CLEO detector. We find A_{CP}(B ->
K*(892)+- pi-+) = 0.26+0.33-0.34(stat.)+0.10-0.08(syst.), giving an allowed
interval of [-0.31,0.78] at the 90% confidence level.Comment: 7 pages postscript, also available through
http://w4.lns.cornell.edu/public/CLNS, submitted to PR
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