Origin of strange metallic phase in cuprate superconductors

The origin of strange metallic phase is shown to exist due to these two conditions---(i) the electrons are strongly interacting such that there are no band and Mott-Hubbard gaps, and (ii) the electronic energy levels are crossed in such a way that there is an electronic energy gap between two energy levels associated to two different wave functions. The theory is also exploited to explain (i) the upward- and downward-shifts in the $T$-linear resistivity curves, and (ii) the spectral weight transfer observed in the soft X-ray absorption spectroscopic measurements of the La-Sr-Cu-O Mott insulator.Comment: To be published in J. Supercond. Nov. Mag

The role of V5/MT+ in the control of catching movements: an rTMS study

Milner and Goodale [Milner, A. D., & Goodale, M. A. (1995). The visual brain in action. Oxford: Oxford University Press] described a model which distinguishes between two visual streams in the brain. It is claimed that the ventral stream serves object recognition (i.e. vision for perception), and the dorsal streams provides visual information for the guidance of action (i.e. vision for action). This model is supported by evidence from the domain of spatial vision, but it remains unclear how motion vision fits into that model. More specifically, it is unclear how the motion complex V5/MT contributes to vision for perception and vision for action. We addressed this question in an earlier study with the V5-lesioned patient LM [Schenk, T., Mai, N., Ditterich, J., & Zihl, J. (2000). Can a motion-blind patient reach for moving objects? European Journal of Neuroscience, 12, 3351–3360]. We found that she is not only impaired in perceptual tasks but also in catching, suggesting a role for V5/MT+ in vision for both perception and action. However, LM's lesion goes beyond V5/MT+ into more dorsal regions. It is thus possible, that the catching deficit was not produced by damage to V5/MT+ itself. In this case, one would expect that selective interference with V5/MT+ would have no effect on catching. In the present study we tested this prediction by applying rTMS over V5/MT+ of the left hemisphere while healthy subjects were either performing a catching or a reaching task. We found that V5-TMS reduced the speed of the catching but not the reaching response. These results confirm that V5/MT+ is not only involved in perceptual but also in visuomotor tasks

Intact automatic avoidance of obstacles in patients with visual form agnosia

In everyday life our reaching behaviour has to be guided not only by the location and properties of the target object, but also by the presence of potential obstacles in the workspace. Recent evidence from neglect and optic ataxia patients has suggested that this automatic obstacle avoidance is mediated by the dorsal, rather than the ventral, stream of visual processing. We tested this idea in two studies involving patients with visual form agnosia resulting from bilateral ventral-stream damage. In the first study, we asked patient DF to reach out and pick up a target object in the presence of obstacles placed at varying distances to the left or right of the target. We found that both DF and controls shifted their trajectories away from the potential obstacles and adjusted their grip aperture in such a way as to minimize risk of collision. In a second study, we asked DF and a second patient, SB, to either reach between, or to bisect the space between, two cylinders presented at varying locations. We found that both patients adjusted their reach trajectories to account for shifts in cylinder location in the reaching task, despite showing significantly worse performance than control subjects when asked to make a bisection judgement. Taken together, these data indicate that automatic obstacle avoidance behaviour is spared in our patients with visual form agnosia. We attribute their ability to the functional intactness of the dorsal stream of visual processing, and argue that the ventral stream plays no important role in automatic obstacle avoidance

Frequency Dependence of Magnetopolarizability of Mesoscopic Grains

We calculate average magnetopolarizability of an isolated metallic sample at frequency $\omega$ comparable to the mean level spacing $\Delta$. The frequency dependence of the magnetopolarizability is described by a universal function of $\omega/\Delta$.Comment: 3 pages, 1 figur

Equation of state and magnetic susceptibility of spin polarized isospin asymmetric nuclear matter

Properties of spin polarized isospin asymmetric nuclear matter are studied within the framework of the Brueckner--Hartree--Fock formalism. The single-particle potentials of neutrons and protons with spin up and down are determined for several values of the neutron and proton spin polarizations and the asymmetry parameter. It is found an almost linear and symmetric variation of the single-particle potentials as increasing these parameters. An analytic parametrization of the total energy per particle as a function of the asymmetry and spin polarizations is constructed. This parametrization is employed to compute the magnetic susceptibility of nuclear matter for several values of the asymmetry from neutron to symmetric matter. The results show no indication of a ferromagnetic transition at any density for any asymmetry of nuclear matter.Comment: 23 pages, 8 figures, 2 tables (submitted to Phys. Rev. C

Relic neutrino masses and the highest energy cosmic rays

We consider the possibility that a large fraction of the ultrahigh energy cosmic rays are decay products of Z bosons which were produced in the scattering of ultrahigh energy cosmic neutrinos on cosmological relic neutrinos. We compare the observed ultrahigh energy cosmic ray spectrum with the one predicted in the above Z-burst scenario and determine the required mass of the heaviest relic neutrino as well as the necessary ultrahigh energy cosmic neutrino flux via a maximum likelihood analysis. We show that the value of the neutrino mass obtained in this way is fairly robust against variations in presently unknown quantities, like the amount of neutrino clustering, the universal radio background, and the extragalactic magnetic field, within their anticipated uncertainties. Much stronger systematics arises from different possible assumptions about the diffuse background of ordinary cosmic rays from unresolved astrophysical sources. In the most plausible case that these ordinary cosmic rays are protons of extragalactic origin, one is lead to a required neutrino mass in the range 0.08 eV - 1.3 eV at the 68 % confidence level. This range narrows down considerably if a particular universal radio background is assumed, e.g. to 0.08 eV - 0.40 eV for a large one. The required flux of ultrahigh energy cosmic neutrinos near the resonant energy should be detected in the near future by AMANDA, RICE, and the Pierre Auger Observatory, otherwise the Z-burst scenario will be ruled out.Comment: 19 pages, 22 figures, REVTeX

Large-scale pharmacogenomic study of sulfonylureas and the QT, JT and QRS intervals: CHARGE Pharmacogenomics Working Group

Sulfonylureas, a commonly used class of medication used to treat type 2 diabetes, have been associated with an increased risk of cardiovascular disease. Their effects on QT interval duration and related electrocardiographic phenotypes are potential mechanisms for this adverse effect. In 11 ethnically diverse cohorts that included 71 857 European, African-American and Hispanic/Latino ancestry individuals with repeated measures of medication use and electrocardiogram (ECG) measurements, we conducted a pharmacogenomic genome-wide association study of sulfonylurea use and three ECG phenotypes: QT, JT and QRS intervals. In ancestry-specific meta-analyses, eight novel pharmacogenomic loci met the threshold for genome-wide significance (P<5 × 10−8), and a pharmacokinetic variant in CYP2C9 (rs1057910) that has been associated with sulfonylurea-related treatment effects and other adverse drug reactions in previous studies was replicated. Additional research is needed to replicate the novel findings and to understand their biological basis